Drosophila melanogaster

37 known processes

VhaAC39 (Dmel_CG2934)

Vacuolar H[+]-ATPase C39 subunit

(Aliases: Dmel\CG2934,Vhaac39,CG2934,anon-EST:GressD5,vhaAC39,V-ATPase)

VhaAC39 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ph reduction GO:0045851 7 0.975
regulation of ph GO:0006885 7 0.963
regulation of cellular ph GO:0030641 7 0.936
intracellular ph reduction GO:0051452 7 0.764
monovalent inorganic cation homeostasis GO:0055067 7 0.590
vacuolar acidification GO:0007035 4 0.559
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.538
epithelial cell differentiation GO:0030855 322 0.493
Zebrafish
sensory perception of mechanical stimulus GO:0050954 72 0.463
cation homeostasis GO:0055080 51 0.457
tube development GO:0035295 244 0.393
Zebrafish
tissue morphogenesis GO:0048729 297 0.370
Zebrafish
regulation of cell differentiation GO:0045595 302 0.352
embryonic morphogenesis GO:0048598 206 0.340
Zebrafish
morphogenesis of an epithelium GO:0002009 276 0.303
Zebrafish
sensory perception of sound GO:0007605 56 0.289
epithelial cell development GO:0002064 274 0.250
camera type eye development GO:0043010 4 0.229
Zebrafish
chemical homeostasis GO:0048878 92 0.224
heterocycle catabolic process GO:0046700 166 0.222
growth GO:0040007 359 0.218
positive regulation of macromolecule metabolic process GO:0010604 405 0.198
organic acid metabolic process GO:0006082 103 0.198
epidermis development GO:0008544 65 0.187
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 242 0.177
negative regulation of biosynthetic process GO:0009890 277 0.177
ribonucleoside metabolic process GO:0009119 127 0.177
developmental maturation GO:0021700 172 0.177
cell maturation GO:0048469 144 0.164
retina development in camera type eye GO:0060041 4 0.164
Zebrafish
digestive system development GO:0055123 149 0.153
oxoacid metabolic process GO:0043436 103 0.150
localization of cell GO:0051674 257 0.142
cellular component assembly involved in morphogenesis GO:0010927 151 0.138
Zebrafish
single organism catabolic process GO:0044712 228 0.137
regulation of notch signaling pathway GO:0008593 100 0.129
reactive oxygen species metabolic process GO:0072593 22 0.128
homeostatic process GO:0042592 199 0.124
regionalization GO:0003002 416 0.123
Zebrafish
developmental growth GO:0048589 280 0.123
cellular macromolecule localization GO:0070727 220 0.120
carboxylic acid metabolic process GO:0019752 92 0.119
establishment of planar polarity GO:0001736 87 0.114
purine ribonucleoside catabolic process GO:0046130 112 0.111
body morphogenesis GO:0010171 2 0.111
single organism intracellular transport GO:1902582 207 0.110
actin filament based process GO:0030029 220 0.106
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.104
single organismal cell cell adhesion GO:0016337 45 0.103
organonitrogen compound metabolic process GO:1901564 318 0.103
regulation of molecular function GO:0065009 217 0.103
ameboidal type cell migration GO:0001667 151 0.101
regulation of multicellular organismal development GO:2000026 414 0.100
positive regulation of cellular biosynthetic process GO:0031328 316 0.100
negative regulation of cellular metabolic process GO:0031324 382 0.098
purine ribonucleoside metabolic process GO:0046128 127 0.097
response to abiotic stimulus GO:0009628 341 0.097
axis specification GO:0009798 167 0.096
Zebrafish
cell motility GO:0048870 251 0.095
intracellular transport GO:0046907 228 0.094
biological adhesion GO:0022610 138 0.092
regulation of protein metabolic process GO:0051246 256 0.091
notch signaling pathway GO:0007219 120 0.091
cell migration GO:0016477 238 0.090
positive regulation of catalytic activity GO:0043085 118 0.088
muscle cell differentiation GO:0042692 103 0.082
establishment of tissue polarity GO:0007164 87 0.081
regulation of phosphorus metabolic process GO:0051174 210 0.080
cellular protein localization GO:0034613 160 0.079
striated muscle cell differentiation GO:0051146 90 0.079
negative regulation of cellular biosynthetic process GO:0031327 277 0.076
regulation of hormone levels GO:0010817 40 0.075
actin cytoskeleton organization GO:0030036 206 0.074
negative regulation of cell differentiation GO:0045596 143 0.073
cellular chemical homeostasis GO:0055082 40 0.072
regulation of growth GO:0040008 233 0.070
cellular amino acid metabolic process GO:0006520 61 0.068
intracellular signal transduction GO:0035556 300 0.066
cellular nitrogen compound catabolic process GO:0044270 165 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.065
regulation of intracellular ph GO:0051453 7 0.064
response to organic substance GO:0010033 284 0.063
regulation of protein modification process GO:0031399 112 0.062
muscle structure development GO:0061061 224 0.060
blood circulation GO:0008015 26 0.060
small molecule metabolic process GO:0044281 305 0.059
ovarian follicle cell development GO:0030707 248 0.059
dorsal ventral pattern formation GO:0009953 133 0.058
establishment or maintenance of cell polarity GO:0007163 167 0.057
membrane organization GO:0061024 112 0.057
inorganic ion transmembrane transport GO:0098660 73 0.056
positive regulation of signaling GO:0023056 243 0.056
ribonucleoside triphosphate catabolic process GO:0009203 108 0.056
monovalent inorganic cation transport GO:0015672 40 0.055
purine nucleoside metabolic process GO:0042278 127 0.055
reproductive system development GO:0061458 74 0.054
ovarian follicle cell migration GO:0007297 121 0.052
nucleoside catabolic process GO:0009164 112 0.051
cell adhesion GO:0007155 136 0.050
purine nucleotide catabolic process GO:0006195 109 0.049
head development GO:0060322 135 0.049
Rat
protein modification process GO:0036211 438 0.049
tube morphogenesis GO:0035239 191 0.049
Zebrafish
stem cell differentiation GO:0048863 117 0.048
wing disc morphogenesis GO:0007472 344 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.048
cell proliferation GO:0008283 299 0.047
organic substance catabolic process GO:1901575 308 0.046
regulation of cellular ketone metabolic process GO:0010565 3 0.046
neurological system process GO:0050877 358 0.044
purine ribonucleotide metabolic process GO:0009150 145 0.044
cell cell junction organization GO:0045216 55 0.042
nucleoside triphosphate catabolic process GO:0009143 108 0.042
regulation of cell development GO:0060284 215 0.042
regulation of cell cycle GO:0051726 291 0.041
ribonucleoside catabolic process GO:0042454 112 0.041
purine containing compound catabolic process GO:0072523 112 0.041
death GO:0016265 284 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.040
neural precursor cell proliferation GO:0061351 75 0.040
purine ribonucleotide catabolic process GO:0009154 109 0.040
hair cell differentiation GO:0035315 47 0.039
Zebrafish
regulation of hydrolase activity GO:0051336 97 0.039
endosomal transport GO:0016197 44 0.039
negative regulation of nervous system development GO:0051961 92 0.038
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.038
neuron recognition GO:0008038 101 0.038
single organism cell adhesion GO:0098602 47 0.037
germarium derived egg chamber formation GO:0007293 101 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.036
nucleoside triphosphate metabolic process GO:0009141 120 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
guanosine containing compound catabolic process GO:1901069 74 0.035
cellular cation homeostasis GO:0030003 38 0.035
positive regulation of cell communication GO:0010647 250 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
glycosyl compound catabolic process GO:1901658 112 0.034
catabolic process GO:0009056 409 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of nucleotide catabolic process GO:0030811 48 0.033
cellular catabolic process GO:0044248 372 0.033
gastrulation with mouth forming first GO:0001703 36 0.033
aromatic compound catabolic process GO:0019439 166 0.033
asymmetric protein localization GO:0008105 33 0.033
epithelial cell migration GO:0010631 148 0.031
organophosphate catabolic process GO:0046434 112 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
appendage development GO:0048736 401 0.030
nucleoside metabolic process GO:0009116 127 0.030
positive regulation of developmental process GO:0051094 143 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
eggshell formation GO:0030703 105 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
open tracheal system development GO:0007424 204 0.029
ribonucleotide catabolic process GO:0009261 109 0.029
respiratory system development GO:0060541 213 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.027
protein transport GO:0015031 155 0.027
regulation of cell proliferation GO:0042127 163 0.027
digestive tract morphogenesis GO:0048546 127 0.027
immune system process GO:0002376 347 0.026
tissue migration GO:0090130 155 0.026
regulation of organ morphogenesis GO:2000027 78 0.026
regulation of cell cycle process GO:0010564 181 0.026
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
regulation of catabolic process GO:0009894 170 0.026
regulation of mapk cascade GO:0043408 92 0.025
regulation of catalytic activity GO:0050790 185 0.025
positive regulation of cell motility GO:2000147 3 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
nephron development GO:0072006 3 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
cellular homeostasis GO:0019725 80 0.025
positive regulation of signal transduction GO:0009967 223 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.025
embryonic pattern specification GO:0009880 174 0.024
cell cell junction assembly GO:0007043 38 0.024
ion homeostasis GO:0050801 55 0.024
phosphorylation GO:0016310 294 0.024
negative regulation of cell development GO:0010721 62 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
peptide metabolic process GO:0006518 80 0.022
regulation of nervous system development GO:0051960 248 0.022
single organism biosynthetic process GO:0044711 206 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
mitotic spindle organization GO:0007052 220 0.022
signal transduction by phosphorylation GO:0023014 107 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
oocyte development GO:0048599 124 0.021
chorion containing eggshell formation GO:0007304 105 0.021
negative regulation of molecular function GO:0044092 51 0.021
spindle organization GO:0007051 253 0.021
developmental growth involved in morphogenesis GO:0060560 65 0.021
ion transmembrane transport GO:0034220 122 0.021
establishment of localization in cell GO:0051649 402 0.021
carbohydrate metabolic process GO:0005975 82 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
striated muscle cell development GO:0055002 50 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
nucleotide metabolic process GO:0009117 161 0.020
cellular carbohydrate catabolic process GO:0044275 2 0.020
purine containing compound metabolic process GO:0072521 155 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
epidermal cell differentiation GO:0009913 51 0.019
Zebrafish
nucleotide catabolic process GO:0009166 109 0.019
organic substance transport GO:0071702 257 0.019
positive regulation of multicellular organism growth GO:0040018 21 0.019
border follicle cell migration GO:0007298 113 0.019
positive regulation of molecular function GO:0044093 136 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
Zebrafish
appendage morphogenesis GO:0035107 397 0.019
negative regulation of developmental process GO:0051093 201 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
hormone metabolic process GO:0042445 33 0.018
eggshell chorion assembly GO:0007306 66 0.018
forebrain development GO:0030900 2 0.018
dorsal appendage formation GO:0046843 47 0.018
protein maturation GO:0051604 71 0.018
response to biotic stimulus GO:0009607 294 0.018
development of primary sexual characteristics GO:0045137 50 0.018
wing disc dorsal ventral pattern formation GO:0048190 47 0.017
metal ion homeostasis GO:0055065 44 0.017
inorganic cation transmembrane transport GO:0098662 61 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
oocyte construction GO:0007308 112 0.017
gland development GO:0048732 191 0.017
multicellular organismal homeostasis GO:0048871 41 0.017
cellular polysaccharide metabolic process GO:0044264 11 0.017
skin development GO:0043588 65 0.017
Zebrafish
positive regulation of biosynthetic process GO:0009891 316 0.016
dephosphorylation GO:0016311 51 0.016
ion transport GO:0006811 145 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
kidney development GO:0001822 3 0.016
Zebrafish
imaginal disc derived appendage development GO:0048737 399 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
circulatory system process GO:0003013 37 0.016
negative regulation of gene expression GO:0010629 387 0.015
regulation of cell projection organization GO:0031344 92 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
myotube differentiation GO:0014902 46 0.015
cation transport GO:0006812 110 0.015
positive regulation of gtp catabolic process GO:0033126 43 0.015
protein phosphorylation GO:0006468 169 0.015
oocyte axis specification GO:0007309 108 0.015
cell recognition GO:0008037 102 0.015
carboxylic acid catabolic process GO:0046395 16 0.015
response to lipopolysaccharide GO:0032496 4 0.015
cellular ketone metabolic process GO:0042180 24 0.014
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.014
mesoderm development GO:0007498 78 0.014
hindbrain development GO:0030902 2 0.014
cellular response to organic substance GO:0071310 132 0.014
cell aging GO:0007569 2 0.014
telencephalon development GO:0021537 2 0.014
anterior posterior pattern specification GO:0009952 136 0.014
establishment of body hair or bristle planar orientation GO:0048104 6 0.014
cuticle development GO:0042335 86 0.014
cellular carbohydrate metabolic process GO:0044262 22 0.014
very long chain fatty acid catabolic process GO:0042760 2 0.014
heart process GO:0003015 37 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
gastrulation GO:0007369 70 0.013
negative regulation of signaling GO:0023057 219 0.013
establishment of protein localization GO:0045184 163 0.013
immune response GO:0006955 246 0.013
response to decreased oxygen levels GO:0036293 58 0.013
response to external biotic stimulus GO:0043207 293 0.013
stem cell development GO:0048864 79 0.013
protein localization GO:0008104 284 0.013
oocyte differentiation GO:0009994 145 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
proteolysis GO:0006508 192 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
cellularization GO:0007349 90 0.013
mitotic nuclear division GO:0007067 213 0.013
cellular ion homeostasis GO:0006873 39 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
wound healing GO:0042060 75 0.013
regulation of phosphorylation GO:0042325 147 0.013
positive regulation of transport GO:0051050 92 0.012
gtp catabolic process GO:0006184 72 0.012
macromolecular complex disassembly GO:0032984 37 0.012
gonad development GO:0008406 50 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
rna localization GO:0006403 115 0.012
apoptotic process GO:0006915 159 0.012
nephron tubule morphogenesis GO:0072078 3 0.012
cellular protein modification process GO:0006464 438 0.012
wnt signaling pathway GO:0016055 98 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
positive regulation of cell size GO:0045793 21 0.012
skeletal muscle organ development GO:0060538 48 0.012
embryonic organ development GO:0048568 50 0.012
Zebrafish
kidney morphogenesis GO:0060993 3 0.012
lipid modification GO:0030258 24 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
morphogenesis of a branching structure GO:0001763 45 0.011
smoothened signaling pathway GO:0007224 49 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
regulation of neural precursor cell proliferation GO:2000177 35 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
renal tubule development GO:0061326 64 0.011
imaginal disc growth GO:0007446 37 0.011
phagocytosis GO:0006909 215 0.011
protein complex biogenesis GO:0070271 201 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
regulation of proteolysis GO:0030162 87 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
reproductive structure development GO:0048608 74 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
immune system development GO:0002520 57 0.011
cell junction organization GO:0034330 57 0.010
heart contraction GO:0060047 26 0.010
anion transport GO:0006820 41 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
sex differentiation GO:0007548 81 0.010
positive regulation of notch signaling pathway GO:0045747 34 0.010
membrane fusion GO:0061025 42 0.010
hemopoiesis GO:0030097 46 0.010
activation of cysteine type endopeptidase activity GO:0097202 17 0.010
dendrite development GO:0016358 204 0.010
positive regulation of viral process GO:0048524 2 0.010
estrogen metabolic process GO:0008210 1 0.010

VhaAC39 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.101
renal tubular transport disease DOID:447 0 0.063
kidney disease DOID:557 0 0.063
urinary system disease DOID:18 0 0.063
auditory system disease DOID:2742 0 0.030
sensory system disease DOID:0050155 0 0.030
nervous system disease DOID:863 0 0.030
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010