Drosophila melanogaster

22 known processes

amd (Dmel_CG10501)

alpha methyl dopa-resistant

(Aliases: CG10501,l(2)37Bk,l(2)amd,l(2)amd alpha-methyldopa hypersensitive,l(2)amd[H],X04695,CG17345,fAMD,Dmel\CG10501)

amd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.123
imaginal disc derived appendage morphogenesis GO:0035114 395 0.118
appendage morphogenesis GO:0035107 397 0.103
epithelial cell differentiation GO:0030855 322 0.099
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.096
positive regulation of rna metabolic process GO:0051254 271 0.088
wing disc morphogenesis GO:0007472 344 0.087
single organism behavior GO:0044708 391 0.078
Fly
response to oxygen containing compound GO:1901700 200 0.069
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.066
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.066
regulation of multicellular organismal development GO:2000026 414 0.065
Fly
response to abiotic stimulus GO:0009628 341 0.063
Fly
appendage development GO:0048736 401 0.063
organonitrogen compound biosynthetic process GO:1901566 117 0.062
Fly
response to anesthetic GO:0072347 9 0.062
positive regulation of rna biosynthetic process GO:1902680 266 0.062
imaginal disc derived appendage development GO:0048737 399 0.057
carbohydrate derivative biosynthetic process GO:1901137 85 0.053
body morphogenesis GO:0010171 2 0.052
epithelial cell development GO:0002064 274 0.051
locomotory behavior GO:0007626 176 0.050
Fly
response to organic substance GO:0010033 284 0.050
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.047
carbohydrate derivative metabolic process GO:1901135 217 0.047
multicellular organismal aging GO:0010259 140 0.047
sulfur compound metabolic process GO:0006790 59 0.044
developmental growth GO:0048589 280 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
nucleotide metabolic process GO:0009117 161 0.042
death GO:0016265 284 0.040
transmembrane transport GO:0055085 139 0.039
small molecule metabolic process GO:0044281 305 0.039
Fly
single organism biosynthetic process GO:0044711 206 0.039
Fly
aging GO:0007568 143 0.039
oxoacid metabolic process GO:0043436 103 0.038
Fly
organonitrogen compound metabolic process GO:1901564 318 0.038
response to oxygen radical GO:0000305 3 0.037
regionalization GO:0003002 416 0.037
regulation of anatomical structure size GO:0090066 163 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.035
forebrain development GO:0030900 2 0.034
purine nucleoside metabolic process GO:0042278 127 0.034
positive regulation of transcription dna templated GO:0045893 266 0.034
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.032
ribonucleotide metabolic process GO:0009259 145 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
cellular response to uv GO:0034644 12 0.031
negative regulation of biosynthetic process GO:0009890 277 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.030
negative regulation of gene expression GO:0010629 387 0.030
cell migration GO:0016477 238 0.029
chorion containing eggshell formation GO:0007304 105 0.029
cell motility GO:0048870 251 0.029
wound healing GO:0042060 75 0.029
cellular response to chemical stimulus GO:0070887 199 0.029
metal ion transport GO:0030001 74 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
enzyme linked receptor protein signaling pathway GO:0007167 179 0.028
female meiotic division GO:0007143 70 0.028
extracellular structure organization GO:0043062 46 0.028
response to temperature stimulus GO:0009266 106 0.027
Fly
camera type eye development GO:0043010 4 0.027
response to alcohol GO:0097305 95 0.027
localization of cell GO:0051674 257 0.027
detection of abiotic stimulus GO:0009582 66 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.026
anatomical structure homeostasis GO:0060249 97 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
ion transmembrane transport GO:0034220 122 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
molting cycle chitin based cuticle GO:0007591 56 0.026
Fly
purine ribonucleoside metabolic process GO:0046128 127 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
response to external biotic stimulus GO:0043207 293 0.025
detection of stimulus GO:0051606 156 0.025
response to nitrogen compound GO:1901698 90 0.025
Fly
purine nucleotide metabolic process GO:0006163 146 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
lipid metabolic process GO:0006629 121 0.025
gland development GO:0048732 191 0.025
alditol phosphate metabolic process GO:0052646 2 0.024
eye photoreceptor cell differentiation GO:0001754 145 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
ovarian follicle cell development GO:0030707 248 0.024
sulfur compound biosynthetic process GO:0044272 16 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
cellular catabolic process GO:0044248 372 0.024
protein modification process GO:0036211 438 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
humoral immune response GO:0006959 117 0.023
response to other organism GO:0051707 293 0.023
meiotic cell cycle process GO:1903046 132 0.023
developmental pigmentation GO:0048066 68 0.023
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.023
regulation of cell cycle GO:0051726 291 0.023
phagocytosis GO:0006909 215 0.023
detection of light stimulus GO:0009583 58 0.022
vesicle mediated transport GO:0016192 381 0.022
positive regulation of gene expression GO:0010628 290 0.022
endocytosis GO:0006897 310 0.022
phosphate ion transport GO:0006817 4 0.022
regulation of cellular response to oxidative stress GO:1900407 4 0.022
immune system process GO:0002376 347 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
imaginal disc derived leg morphogenesis GO:0007480 80 0.021
determination of adult lifespan GO:0008340 137 0.021
inorganic ion transmembrane transport GO:0098660 73 0.021
retina development in camera type eye GO:0060041 4 0.021
cellular lipid metabolic process GO:0044255 83 0.021
cellular protein modification process GO:0006464 438 0.021
purine containing compound metabolic process GO:0072521 155 0.021
tissue morphogenesis GO:0048729 297 0.020
embryonic morphogenesis GO:0048598 206 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
response to wounding GO:0009611 94 0.020
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
Fly
growth GO:0040007 359 0.020
Fly
axon guidance GO:0007411 233 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
Fly
segmentation GO:0035282 207 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
biological adhesion GO:0022610 138 0.019
nucleoside metabolic process GO:0009116 127 0.019
anterior posterior axis specification GO:0009948 109 0.019
positive regulation of cell communication GO:0010647 250 0.019
intracellular protein transmembrane transport GO:0065002 4 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
organophosphate metabolic process GO:0019637 195 0.019
eggshell formation GO:0030703 105 0.019
negative regulation of developmental process GO:0051093 201 0.019
neuropeptide signaling pathway GO:0007218 45 0.019
respiratory system development GO:0060541 213 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
histolysis GO:0007559 102 0.018
chromatin modification GO:0016568 147 0.018
regulation of catalytic activity GO:0050790 185 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
regulation of immune system process GO:0002682 176 0.018
cation transmembrane transport GO:0098655 88 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
positive regulation of cell death GO:0010942 69 0.018
response to radiation GO:0009314 155 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
neuron projection guidance GO:0097485 241 0.018
extracellular matrix disassembly GO:0022617 4 0.018
female meiosis chromosome segregation GO:0016321 33 0.018
positive regulation of signaling GO:0023056 243 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
reactive oxygen species metabolic process GO:0072593 22 0.017
actin filament based process GO:0030029 220 0.017
dorsal ventral axis specification GO:0009950 66 0.017
cell death GO:0008219 279 0.017
chromosome separation GO:0051304 42 0.017
purine nucleoside biosynthetic process GO:0042451 3 0.017
detection of external stimulus GO:0009581 66 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
response to hypoxia GO:0001666 53 0.017
regulation of body fluid levels GO:0050878 14 0.017
regulation of cell cycle process GO:0010564 181 0.017
bmp signaling pathway GO:0030509 27 0.017
programmed cell death GO:0012501 257 0.016
ion transport GO:0006811 145 0.016
atp metabolic process GO:0046034 49 0.016
regulation of molecular function GO:0065009 217 0.016
synaptic transmission GO:0007268 288 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
cell division GO:0051301 248 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
torso signaling pathway GO:0008293 21 0.016
male gamete generation GO:0048232 201 0.016
chromosome organization GO:0051276 360 0.016
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
immune effector process GO:0002252 98 0.016
purine ribonucleotide biosynthetic process GO:0009152 28 0.016
axon development GO:0061564 297 0.016
regulation of response to stress GO:0080134 200 0.016
tissue death GO:0016271 102 0.016
cell junction assembly GO:0034329 42 0.016
regulation of developmental growth GO:0048638 174 0.015
positive regulation of lipid storage GO:0010884 4 0.015
ribonucleoside biosynthetic process GO:0042455 3 0.015
tripartite regional subdivision GO:0007351 103 0.015
antimicrobial humoral response GO:0019730 99 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.015
response to endogenous stimulus GO:0009719 119 0.015
Fly
spermatogenesis GO:0007283 200 0.015
organelle fission GO:0048285 340 0.015
leg disc development GO:0035218 92 0.015
embryonic pattern specification GO:0009880 174 0.015
dna double strand break processing GO:0000729 3 0.015
catabolic process GO:0009056 409 0.015
purine ribonucleoside biosynthetic process GO:0046129 3 0.015
chaeta development GO:0022416 97 0.015
glycoprotein metabolic process GO:0009100 41 0.015
imaginal disc pattern formation GO:0007447 91 0.015
camera type eye morphogenesis GO:0048593 2 0.015
chromatin organization GO:0006325 207 0.015
steroid catabolic process GO:0006706 1 0.015
anion homeostasis GO:0055081 3 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
wing disc pattern formation GO:0035222 66 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.014
salivary gland histolysis GO:0035070 88 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
pigmentation GO:0043473 75 0.014
Fly
positive regulation of programmed cell death GO:0043068 62 0.014
immune response GO:0006955 246 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
aromatic compound catabolic process GO:0019439 166 0.014
response to lipopolysaccharide GO:0032496 4 0.014
oocyte maturation GO:0001556 3 0.014
response to copper ion GO:0046688 4 0.014
covalent chromatin modification GO:0016569 106 0.014
phototransduction GO:0007602 52 0.014
mrna metabolic process GO:0016071 124 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
autophagic cell death GO:0048102 83 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of transport GO:0051049 181 0.014
regulation of cell death GO:0010941 173 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
carbohydrate metabolic process GO:0005975 82 0.014
cuticle development GO:0042335 86 0.013
hindgut morphogenesis GO:0007442 58 0.013
meiotic cell cycle GO:0051321 171 0.013
macromolecule catabolic process GO:0009057 161 0.013
regulation of response to oxidative stress GO:1902882 4 0.013
gliogenesis GO:0042063 80 0.013
dna damage checkpoint GO:0000077 78 0.013
meiosis i GO:0007127 59 0.013
mitotic nuclear division GO:0007067 213 0.013
wnt signaling pathway GO:0016055 98 0.013
response to organic cyclic compound GO:0014070 89 0.013
Fly
cellular modified amino acid metabolic process GO:0006575 45 0.013
cell cell junction organization GO:0045216 55 0.013
cellular ketone metabolic process GO:0042180 24 0.013
germ cell migration GO:0008354 43 0.013
anterior posterior pattern specification GO:0009952 136 0.013
nuclear division GO:0000280 332 0.013
glycoprotein biosynthetic process GO:0009101 41 0.013
cell aging GO:0007569 2 0.013
neuroblast proliferation GO:0007405 74 0.013
regulation of mitosis GO:0007088 56 0.013
open tracheal system development GO:0007424 204 0.013
cell proliferation GO:0008283 299 0.013
cell cycle phase transition GO:0044770 140 0.013
water homeostasis GO:0030104 3 0.013
establishment of localization in cell GO:0051649 402 0.013
single organism membrane organization GO:0044802 93 0.013
cellular amine metabolic process GO:0044106 12 0.013
Fly
regulation of growth GO:0040008 233 0.013
mitotic cell cycle embryonic GO:0045448 38 0.013
response to oxidative stress GO:0006979 86 0.012
regulation of cell projection organization GO:0031344 92 0.012
organic acid metabolic process GO:0006082 103 0.012
Fly
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
response to ethanol GO:0045471 59 0.012
organic substance transport GO:0071702 257 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
chemotaxis GO:0006935 249 0.012
toxin metabolic process GO:0009404 2 0.012
developmental programmed cell death GO:0010623 138 0.012
response to oxygen levels GO:0070482 59 0.012
cellular response to ionizing radiation GO:0071479 15 0.012
stem cell differentiation GO:0048863 117 0.012
chromosome segregation GO:0007059 157 0.012
chaeta morphogenesis GO:0008407 42 0.012
meiotic nuclear division GO:0007126 151 0.012
connective tissue development GO:0061448 3 0.012
regulation of organelle organization GO:0033043 196 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
regulation of cell shape GO:0008360 113 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
negative regulation of cellular response to oxidative stress GO:1900408 1 0.012
cellular homeostasis GO:0019725 80 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
telencephalon development GO:0021537 2 0.012
developmental maturation GO:0021700 172 0.012
Fly
response to nutrient levels GO:0031667 114 0.012
regulation of developmental pigmentation GO:0048070 24 0.012
Fly
regulation of response to external stimulus GO:0032101 115 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
hindgut development GO:0061525 58 0.012
primary amino compound biosynthetic process GO:1901162 2 0.012
Fly
cellular response to dna damage stimulus GO:0006974 223 0.012
organic substance catabolic process GO:1901575 308 0.012
protein transmembrane transport GO:0071806 4 0.012
molting cycle process GO:0022404 29 0.012
Fly
apoptotic process GO:0006915 159 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
rna processing GO:0006396 147 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
axis specification GO:0009798 167 0.011
regulation of meiosis GO:0040020 3 0.011
blastoderm segmentation GO:0007350 159 0.011
leg disc morphogenesis GO:0007478 80 0.011
oxidation reduction process GO:0055114 123 0.011
positive regulation of transport GO:0051050 92 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
cation transport GO:0006812 110 0.011
ras protein signal transduction GO:0007265 88 0.011
glycosyl compound biosynthetic process GO:1901659 3 0.011
adult chitin containing cuticle pigmentation GO:0048085 16 0.011
Fly
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
negative regulation of cell communication GO:0010648 223 0.011
digestive tract development GO:0048565 149 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
endomembrane system organization GO:0010256 119 0.011
nucleoside biosynthetic process GO:0009163 3 0.011
regulation of tube length open tracheal system GO:0035159 24 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
positive regulation of signal transduction GO:0009967 223 0.011
behavioral response to pain GO:0048266 3 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
defense response to other organism GO:0098542 225 0.011
amine metabolic process GO:0009308 12 0.011
Fly
positive regulation of atp catabolic process GO:1903291 3 0.011
aggressive behavior GO:0002118 63 0.011
rna localization GO:0006403 115 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
positive regulation of cell motility GO:2000147 3 0.011
autophagy GO:0006914 108 0.011
oocyte differentiation GO:0009994 145 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
glutathione metabolic process GO:0006749 37 0.011
regulation of tube size open tracheal system GO:0035151 43 0.011
single organism catabolic process GO:0044712 228 0.011
response to heat GO:0009408 63 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
response to organonitrogen compound GO:0010243 75 0.010
Fly
cuticle pigmentation GO:0048067 22 0.010
Fly
dna integrity checkpoint GO:0031570 81 0.010
positive regulation of response to external stimulus GO:0032103 44 0.010
eye development GO:0001654 323 0.010
myotube cell development GO:0014904 3 0.010
multi organism behavior GO:0051705 175 0.010
Fly
response to monosaccharide GO:0034284 4 0.010
positive regulation of mitotic cell cycle GO:0045931 34 0.010
sensory perception of mechanical stimulus GO:0050954 72 0.010
regulation of stem cell proliferation GO:0072091 40 0.010
compound eye development GO:0048749 307 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
cell fate specification GO:0001708 71 0.010
response to bacterium GO:0009617 198 0.010
mrna processing GO:0006397 104 0.010
mitochondrion organization GO:0007005 65 0.010
response to extracellular stimulus GO:0009991 116 0.010
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
synapse organization GO:0050808 196 0.010
mitotic g2 m transition checkpoint GO:0044818 70 0.010
chitin based cuticle development GO:0040003 49 0.010
response to decreased oxygen levels GO:0036293 58 0.010
tissue migration GO:0090130 155 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
positive regulation of cell migration GO:0030335 2 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
defense response GO:0006952 300 0.010
regulation of programmed cell death GO:0043067 152 0.010

amd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.017
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.011
nervous system disease DOID:863 0 0.011