Drosophila melanogaster

34 known processes

Kdm4B (Dmel_CG33182)

Histone demethylase 4B

(Aliases: dJMJD2(2),dKDM4B,CG33182,Dmel\CG33182,CG4037)

Kdm4B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
columnar cuboidal epithelial cell development GO:0002066 249 0.076
cell death GO:0008219 279 0.059
Rat
wing disc morphogenesis GO:0007472 344 0.050
epithelial cell migration GO:0010631 148 0.049
death GO:0016265 284 0.047
Rat
dna packaging GO:0006323 91 0.046
establishment of localization in cell GO:0051649 402 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.045
organonitrogen compound metabolic process GO:1901564 318 0.043
response to external biotic stimulus GO:0043207 293 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.043
vesicle mediated transport GO:0016192 381 0.042
intracellular signal transduction GO:0035556 300 0.040
cellular catabolic process GO:0044248 372 0.040
negative regulation of gene expression GO:0010629 387 0.038
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.035
response to abiotic stimulus GO:0009628 341 0.035
positive regulation of response to stimulus GO:0048584 323 0.035
cellular protein modification process GO:0006464 438 0.035
appendage morphogenesis GO:0035107 397 0.035
defense response GO:0006952 300 0.034
appendage development GO:0048736 401 0.033
cell motility GO:0048870 251 0.032
phosphorylation GO:0016310 294 0.032
growth GO:0040007 359 0.032
response to other organism GO:0051707 293 0.031
endocytosis GO:0006897 310 0.031
organic substance catabolic process GO:1901575 308 0.031
imaginal disc derived appendage development GO:0048737 399 0.030
protein modification process GO:0036211 438 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.029
response to biotic stimulus GO:0009607 294 0.029
meiotic cell cycle process GO:1903046 132 0.029
catabolic process GO:0009056 409 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
dna conformation change GO:0071103 105 0.028
regulation of cell differentiation GO:0045595 302 0.027
Rat
cellular response to abiotic stimulus GO:0071214 58 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.025
epithelial cell development GO:0002064 274 0.025
ovarian follicle cell development GO:0030707 248 0.025
protein localization GO:0008104 284 0.024
phagocytosis GO:0006909 215 0.024
regulation of cell death GO:0010941 173 0.024
Rat
forebrain development GO:0030900 2 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
Rat Fly
immune response GO:0006955 246 0.023
chromatin organization GO:0006325 207 0.022
response to ionizing radiation GO:0010212 32 0.022
dna metabolic process GO:0006259 227 0.022
intracellular transport GO:0046907 228 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
small molecule metabolic process GO:0044281 305 0.022
positive regulation of signal transduction GO:0009967 223 0.022
regulation of protein metabolic process GO:0051246 256 0.022
proteolysis GO:0006508 192 0.021
ameboidal type cell migration GO:0001667 151 0.021
regulation of nervous system development GO:0051960 248 0.021
Rat
ras protein signal transduction GO:0007265 88 0.021
compound eye development GO:0048749 307 0.021
regulation of cell cycle GO:0051726 291 0.021
organic substance transport GO:0071702 257 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
gene silencing GO:0016458 138 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
negative regulation of developmental process GO:0051093 201 0.021
Rat
regulation of localization GO:0032879 275 0.020
programmed cell death GO:0012501 257 0.020
compound eye morphogenesis GO:0001745 249 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
Rat
carboxylic acid metabolic process GO:0019752 92 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
positive regulation of signaling GO:0023056 243 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
response to radiation GO:0009314 155 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of response to stress GO:0080134 200 0.019
body morphogenesis GO:0010171 2 0.019
sensory perception GO:0007600 196 0.019
response to bacterium GO:0009617 198 0.019
cellular amide metabolic process GO:0043603 80 0.019
cellular macromolecule localization GO:0070727 220 0.019
protein complex biogenesis GO:0070271 201 0.019
organelle fission GO:0048285 340 0.019
negative regulation of signal transduction GO:0009968 206 0.019
immune system process GO:0002376 347 0.019
epithelium migration GO:0090132 148 0.019
regulation of cellular component biogenesis GO:0044087 201 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
protein complex assembly GO:0006461 200 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
neurological system process GO:0050877 358 0.018
synapse organization GO:0050808 196 0.018
aromatic compound catabolic process GO:0019439 166 0.018
telencephalon development GO:0021537 2 0.018
spindle organization GO:0007051 253 0.017
single organism intracellular transport GO:1902582 207 0.017
tissue migration GO:0090130 155 0.017
alternative mrna splicing via spliceosome GO:0000380 60 0.017
response to lipopolysaccharide GO:0032496 4 0.017
regulation of catalytic activity GO:0050790 185 0.017
positive regulation of cell communication GO:0010647 250 0.017
cell proliferation GO:0008283 299 0.017
Human
negative regulation of signaling GO:0023057 219 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
Human
regulation of intracellular signal transduction GO:1902531 236 0.017
macromolecular complex assembly GO:0065003 256 0.017
cellular response to radiation GO:0071478 52 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
Human
regulation of cell cycle process GO:0010564 181 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
apoptotic process GO:0006915 159 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
chromatin assembly or disassembly GO:0006333 52 0.016
epithelial cell differentiation GO:0030855 322 0.016
defense response to other organism GO:0098542 225 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
eye development GO:0001654 323 0.016
oxoacid metabolic process GO:0043436 103 0.016
establishment of protein localization GO:0045184 163 0.016
nucleosome organization GO:0034728 59 0.016
response to organic substance GO:0010033 284 0.015
cell migration GO:0016477 238 0.015
chromatin assembly GO:0031497 48 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
peptidyl amino acid modification GO:0018193 105 0.015
gland morphogenesis GO:0022612 145 0.015
chemotaxis GO:0006935 249 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
pigment metabolic process GO:0042440 84 0.015
nucleotide metabolic process GO:0009117 161 0.015
heterocycle catabolic process GO:0046700 166 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
Human
ion transport GO:0006811 145 0.015
meiotic cell cycle GO:0051321 171 0.015
amine metabolic process GO:0009308 12 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
Human
establishment or maintenance of cell polarity GO:0007163 167 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
protein transport GO:0015031 155 0.014
cytoplasmic transport GO:0016482 130 0.014
defense response to bacterium GO:0042742 178 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
regulation of apoptotic process GO:0042981 130 0.014
antimicrobial humoral response GO:0019730 99 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
axon guidance GO:0007411 233 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of rna splicing GO:0043484 69 0.014
chromosome organization GO:0051276 360 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
Human
regulation of catabolic process GO:0009894 170 0.014
organophosphate catabolic process GO:0046434 112 0.014
rna processing GO:0006396 147 0.014
protein ubiquitination GO:0016567 70 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
protein processing GO:0016485 68 0.014
rna localization GO:0006403 115 0.014
regulation of organelle organization GO:0033043 196 0.014
cellular amine metabolic process GO:0044106 12 0.014
macromolecule catabolic process GO:0009057 161 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
cell division GO:0051301 248 0.014
single organism biosynthetic process GO:0044711 206 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
mapk cascade GO:0000165 107 0.014
acylglycerol catabolic process GO:0046464 3 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
single organism behavior GO:0044708 391 0.013
regulation of growth GO:0040008 233 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
regulation of molecular function GO:0065009 217 0.013
anterior posterior pattern specification GO:0009952 136 0.013
organic acid metabolic process GO:0006082 103 0.013
innate immune response GO:0045087 144 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
exocrine system development GO:0035272 162 0.013
taxis GO:0042330 304 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of mrna metabolic process GO:1903311 72 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
Mouse
positive regulation of phosphorylation GO:0042327 87 0.013
border follicle cell migration GO:0007298 113 0.013
regulation of phosphorylation GO:0042325 147 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
Human
organophosphate metabolic process GO:0019637 195 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
histolysis GO:0007559 102 0.013
dendrite development GO:0016358 204 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
nucleotide catabolic process GO:0009166 109 0.012
regulation of cell proliferation GO:0042127 163 0.012
Human
regulation of transport GO:0051049 181 0.012
pyridine containing compound metabolic process GO:0072524 3 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
axis specification GO:0009798 167 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
Human
developmental growth GO:0048589 280 0.012
regionalization GO:0003002 416 0.012
protein maturation GO:0051604 71 0.012
regulation of programmed cell death GO:0043067 152 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
cellularization GO:0007349 90 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
axon development GO:0061564 297 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
segmentation GO:0035282 207 0.012
glycoprotein metabolic process GO:0009100 41 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
chromosome segregation GO:0007059 157 0.012
male gamete generation GO:0048232 201 0.012
response to organophosphorus GO:0046683 2 0.012
adult behavior GO:0030534 137 0.012
spermatogenesis GO:0007283 200 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
negative regulation of cell communication GO:0010648 223 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
mitotic spindle organization GO:0007052 220 0.012
muscle organ development GO:0007517 127 0.011
blastoderm segmentation GO:0007350 159 0.011
nucleoside metabolic process GO:0009116 127 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
microtubule organizing center organization GO:0031023 168 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
regulation of immune system process GO:0002682 176 0.011
sterol homeostasis GO:0055092 4 0.011
axonogenesis GO:0007409 290 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
nuclear transport GO:0051169 72 0.011
regulation of response to external stimulus GO:0032101 115 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
secretion by cell GO:0032940 101 0.011
mrna metabolic process GO:0016071 124 0.011
rna splicing GO:0008380 83 0.011
spermatid differentiation GO:0048515 114 0.011
nucleoside catabolic process GO:0009164 112 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
regulation of proteolysis GO:0030162 87 0.011
regulation of multi organism process GO:0043900 131 0.011
meiotic nuclear division GO:0007126 151 0.011
open tracheal system development GO:0007424 204 0.011
cation transport GO:0006812 110 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
embryonic pattern specification GO:0009880 174 0.011
intracellular protein transport GO:0006886 104 0.011
purine containing compound metabolic process GO:0072521 155 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
centrosome organization GO:0051297 163 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
salivary gland development GO:0007431 162 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
protein dna complex subunit organization GO:0071824 86 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
secretion GO:0046903 109 0.010
central nervous system development GO:0007417 201 0.010
Rat
salivary gland cell autophagic cell death GO:0035071 83 0.010
cellular protein catabolic process GO:0044257 83 0.010
peptide metabolic process GO:0006518 80 0.010
cellular response to ionizing radiation GO:0071479 15 0.010
mrna processing GO:0006397 104 0.010
modification dependent macromolecule catabolic process GO:0043632 79 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
notch signaling pathway GO:0007219 120 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
protein phosphorylation GO:0006468 169 0.010
regulation of mrna processing GO:0050684 71 0.010
single organism nuclear import GO:1902593 51 0.010
oocyte development GO:0048599 124 0.010
neuron projection guidance GO:0097485 241 0.010
positive regulation of transport GO:0051050 92 0.010
neuron recognition GO:0008038 101 0.010

Kdm4B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of metabolism DOID:0014667 0 0.016
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014
inherited metabolic disorder DOID:655 0 0.012