Drosophila melanogaster

122 known processes

Cep135 (Dmel_CG17081)

CG17081 gene product from transcript CG17081-RB

(Aliases: bld10,DCep135,CG17081,dbld10,Bld10p,Dmel\CG17081)

Cep135 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centriole replication GO:0007099 24 0.961
cilium organization GO:0044782 41 0.886
meiotic nuclear division GO:0007126 151 0.810
organelle assembly GO:0070925 198 0.786
centriole assembly GO:0098534 24 0.762
microtubule organizing center organization GO:0031023 168 0.730
sperm axoneme assembly GO:0007288 13 0.683
cilium morphogenesis GO:0060271 39 0.678
centrosome duplication GO:0051298 121 0.638
mitotic spindle organization GO:0007052 220 0.631
cilium assembly GO:0042384 38 0.627
asymmetric neuroblast division GO:0055059 33 0.626
spindle organization GO:0007051 253 0.531
cell projection assembly GO:0030031 94 0.494
microtubule bundle formation GO:0001578 27 0.421
male meiosis GO:0007140 52 0.361
centrosome organization GO:0051297 163 0.331
centrosome cycle GO:0007098 137 0.310
axoneme assembly GO:0035082 18 0.268
neuroblast division GO:0055057 35 0.198
cellular component assembly involved in morphogenesis GO:0010927 151 0.196
regulation of microtubule based process GO:0032886 49 0.189
male meiosis cytokinesis GO:0007112 26 0.154
sperm motility GO:0030317 12 0.152
centriole centriole cohesion GO:0010457 5 0.151
Human
spermatogenesis GO:0007283 200 0.146
sensory perception of mechanical stimulus GO:0050954 72 0.129
meiotic cell cycle GO:0051321 171 0.128
cell division GO:0051301 248 0.125
male gamete generation GO:0048232 201 0.120
meiotic cell cycle process GO:1903046 132 0.117
regulation of small gtpase mediated signal transduction GO:0051056 93 0.103
nuclear division GO:0000280 332 0.091
organophosphate metabolic process GO:0019637 195 0.090
ras protein signal transduction GO:0007265 88 0.087
neuronal stem cell division GO:0036445 35 0.086
protein localization GO:0008104 284 0.083
snrna metabolic process GO:0016073 14 0.081
cell maturation GO:0048469 144 0.073
centrosome separation GO:0051299 20 0.072
cellular macromolecule localization GO:0070727 220 0.072
small gtpase mediated signal transduction GO:0007264 88 0.071
spermatid differentiation GO:0048515 114 0.070
sensory perception GO:0007600 196 0.067
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.067
regulation of intracellular signal transduction GO:1902531 236 0.066
anterior posterior pattern specification GO:0009952 136 0.065
maintenance of location in cell GO:0051651 28 0.065
regionalization GO:0003002 416 0.062
regulation of cytoskeleton organization GO:0051493 89 0.061
microtubule anchoring GO:0034453 11 0.060
negative regulation of response to stimulus GO:0048585 258 0.058
embryonic pattern specification GO:0009880 174 0.057
cytoskeleton dependent cytokinesis GO:0061640 81 0.056
intracellular signal transduction GO:0035556 300 0.056
regulation of protein complex disassembly GO:0043244 29 0.053
negative regulation of synapse assembly GO:0051964 39 0.050
organelle fission GO:0048285 340 0.048
blastoderm segmentation GO:0007350 159 0.048
spindle assembly involved in mitosis GO:0090307 50 0.046
cellular protein localization GO:0034613 160 0.045
small molecule metabolic process GO:0044281 305 0.044
somatic stem cell division GO:0048103 37 0.044
axis specification GO:0009798 167 0.043
meiosis i GO:0007127 59 0.042
neurological system process GO:0050877 358 0.042
single organism membrane organization GO:0044802 93 0.042
regulation of cell cycle GO:0051726 291 0.041
asymmetric cell division GO:0008356 37 0.041
asymmetric stem cell division GO:0098722 49 0.041
cellular component disassembly GO:0022411 46 0.041
microtubule based movement GO:0007018 51 0.041
cell proliferation GO:0008283 299 0.040
response to organic substance GO:0010033 284 0.040
positive regulation of signaling GO:0023056 243 0.039
nucleotide metabolic process GO:0009117 161 0.038
organonitrogen compound metabolic process GO:1901564 318 0.038
nucleoside catabolic process GO:0009164 112 0.038
sister chromatid segregation GO:0000819 92 0.038
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.038
regulation of localization GO:0032879 275 0.037
stem cell division GO:0017145 69 0.036
endocytosis GO:0006897 310 0.035
regulation of cellular localization GO:0060341 136 0.035
maintenance of protein location in cell GO:0032507 26 0.035
segmentation GO:0035282 207 0.034
meiotic cytokinesis GO:0033206 33 0.034
negative regulation of protein depolymerization GO:1901880 23 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of ras protein signal transduction GO:0046578 93 0.033
regulation of immune response GO:0050776 118 0.033
response to temperature stimulus GO:0009266 106 0.032
organic substance catabolic process GO:1901575 308 0.032
positive regulation of cell communication GO:0010647 250 0.030
snrna 3 end processing GO:0034472 14 0.029
endomembrane system organization GO:0010256 119 0.029
negative regulation of growth GO:0045926 84 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
mitotic cytokinesis GO:0000281 50 0.028
regulation of spindle organization GO:0090224 17 0.027
epithelial cell development GO:0002064 274 0.027
chromosome segregation GO:0007059 157 0.027
establishment of localization in cell GO:0051649 402 0.027
regulation of dendrite morphogenesis GO:0048814 28 0.027
localization of cell GO:0051674 257 0.027
cytokinesis GO:0000910 90 0.026
regulation of protein depolymerization GO:1901879 27 0.026
phosphorylation GO:0016310 294 0.026
neuron projection guidance GO:0097485 241 0.026
establishment of mitotic spindle localization GO:0040001 17 0.026
microtubule based transport GO:0010970 42 0.025
positive regulation of signal transduction GO:0009967 223 0.025
establishment of cell polarity GO:0030010 40 0.025
anterior posterior axis specification embryo GO:0008595 103 0.025
purine containing compound catabolic process GO:0072523 112 0.024
vesicle mediated transport GO:0016192 381 0.024
negative regulation of developmental growth GO:0048640 64 0.024
single organism cellular localization GO:1902580 180 0.024
membrane organization GO:0061024 112 0.024
neural precursor cell proliferation GO:0061351 75 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
actin filament based movement GO:0030048 26 0.024
negative regulation of intracellular signal transduction GO:1902532 57 0.023
alditol phosphate metabolic process GO:0052646 2 0.023
macromolecular complex disassembly GO:0032984 37 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
spindle stabilization GO:0043146 14 0.022
protein phosphorylation GO:0006468 169 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
signal transduction by phosphorylation GO:0023014 107 0.021
negative regulation of signal transduction GO:0009968 206 0.021
golgi organization GO:0007030 66 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
establishment of spindle orientation GO:0051294 18 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
negative regulation of protein complex disassembly GO:0043242 23 0.020
actomyosin contractile ring contraction GO:0000916 12 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
female meiotic division GO:0007143 70 0.020
developmental maturation GO:0021700 172 0.020
negative regulation of cell communication GO:0010648 223 0.020
regulation of growth GO:0040008 233 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
exocrine system development GO:0035272 162 0.019
protein complex localization GO:0031503 4 0.019
regulation of developmental growth GO:0048638 174 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
embryonic axis specification GO:0000578 107 0.019
mitotic spindle stabilization GO:0043148 6 0.019
contractile ring contraction GO:0036213 12 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
regulation of immune system process GO:0002682 176 0.018
maintenance of protein location GO:0045185 28 0.018
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.018
macromolecular complex assembly GO:0065003 256 0.018
maintenance of location GO:0051235 73 0.018
regulation of organelle organization GO:0033043 196 0.018
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.018
regulation of autophagy GO:0010506 62 0.018
nonmotile primary cilium assembly GO:0035058 8 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.017
synaptic transmission GO:0007268 288 0.017
negative regulation of signaling GO:0023057 219 0.017
regulation of transport GO:0051049 181 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.017
nucleotide catabolic process GO:0009166 109 0.017
negative regulation of developmental process GO:0051093 201 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
appendage development GO:0048736 401 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
rna localization GO:0006403 115 0.016
nucleus organization GO:0006997 45 0.016
regulation of intracellular transport GO:0032386 64 0.016
attachment of spindle microtubules to kinetochore GO:0008608 5 0.016
spindle localization GO:0051653 22 0.016
immune response activating signal transduction GO:0002757 2 0.016
cellular amine metabolic process GO:0044106 12 0.016
spindle assembly involved in female meiosis GO:0007056 14 0.016
maternal determination of anterior posterior axis embryo GO:0008358 74 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.015
organophosphate catabolic process GO:0046434 112 0.015
epithelial cell differentiation GO:0030855 322 0.015
mapk cascade GO:0000165 107 0.015
gastrulation GO:0007369 70 0.015
sensory perception of sound GO:0007605 56 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
organonitrogen compound catabolic process GO:1901565 128 0.014
amine metabolic process GO:0009308 12 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
purine nucleoside monophosphate catabolic process GO:0009128 38 0.014
pole cell formation GO:0007279 19 0.014
protein modification process GO:0036211 438 0.014
cell cycle arrest GO:0007050 4 0.014
wing disc morphogenesis GO:0007472 344 0.014
developmental programmed cell death GO:0010623 138 0.014
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.014
single organism catabolic process GO:0044712 228 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
actin filament organization GO:0007015 126 0.014
regulation of mapk cascade GO:0043408 92 0.014
response to bacterium GO:0009617 198 0.014
microtubule polymerization GO:0046785 15 0.014
photoreceptor cell development GO:0042461 96 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
purine nucleoside metabolic process GO:0042278 127 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
cytokinetic process GO:0032506 27 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
oocyte development GO:0048599 124 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
chromosome organization GO:0051276 360 0.013
response to heat GO:0009408 63 0.013
chromosome condensation GO:0030261 41 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
male meiosis chromosome segregation GO:0007060 10 0.013
carbohydrate metabolic process GO:0005975 82 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.013
nucleoside metabolic process GO:0009116 127 0.013
pigmentation GO:0043473 75 0.013
dorsal closure GO:0007391 79 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
nuclear pore organization GO:0006999 1 0.013
regulation of cellular component size GO:0032535 98 0.013
establishment of mitotic spindle orientation GO:0000132 13 0.013
cell motility GO:0048870 251 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
nicotinamide nucleotide metabolic process GO:0046496 2 0.013
mitotic cell cycle embryonic GO:0045448 38 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
cellular protein modification process GO:0006464 438 0.012
cellular protein complex disassembly GO:0043624 35 0.012
mitotic nuclear division GO:0007067 213 0.012
defense response to other organism GO:0098542 225 0.012
spermatid development GO:0007286 98 0.012
phagocytosis GO:0006909 215 0.012
tissue death GO:0016271 102 0.012
cell fate determination GO:0001709 91 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
histolysis GO:0007559 102 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
negative regulation of nervous system development GO:0051961 92 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
protein complex assembly GO:0006461 200 0.011
defense response GO:0006952 300 0.011
ncrna 3 end processing GO:0043628 17 0.011
negative regulation of cytoskeleton organization GO:0051494 30 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
catabolic process GO:0009056 409 0.011
circadian behavior GO:0048512 76 0.011
metaphase plate congression GO:0051310 19 0.011
protein localization to cytoskeleton GO:0044380 2 0.011
body morphogenesis GO:0010171 2 0.011
salivary gland development GO:0007431 162 0.011
aromatic compound catabolic process GO:0019439 166 0.011
macromolecule catabolic process GO:0009057 161 0.011
cellular catabolic process GO:0044248 372 0.011
intracellular mrna localization GO:0008298 66 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
asymmetric protein localization GO:0008105 33 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
appendage morphogenesis GO:0035107 397 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
axon development GO:0061564 297 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
negative regulation of microtubule depolymerization GO:0007026 21 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
photoreceptor cell axon guidance GO:0072499 23 0.011
taxis GO:0042330 304 0.011
atp metabolic process GO:0046034 49 0.010
response to starvation GO:0042594 97 0.010
positive regulation of gene expression GO:0010628 290 0.010
rna processing GO:0006396 147 0.010
axon guidance GO:0007411 233 0.010
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
cytokinetic cell separation GO:0000920 1 0.010
regulation of catabolic process GO:0009894 170 0.010
wound healing GO:0042060 75 0.010
spindle assembly involved in meiosis GO:0090306 20 0.010
actin mediated cell contraction GO:0070252 21 0.010
snrna processing GO:0016180 14 0.010
regulation of locomotion GO:0040012 42 0.010

Cep135 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
cardiovascular system disease DOID:1287 0 0.037
nervous system disease DOID:863 0 0.037
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
disease of cellular proliferation DOID:14566 0 0.017
congenital nervous system abnormality DOID:2490 0 0.014
physical disorder DOID:0080015 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014