Drosophila melanogaster

49 known processes

nab (Dmel_CG33545)

CG33545 gene product from transcript CG33545-RC

(Aliases: Nab,CG33545,l(2)SH3 143,l(3)SH21,Dmel\CG33545,dNAB,l(3)64Aj,l(3)SH143,dnab,CG15001,CG15000)

nab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.950
negative regulation of cellular biosynthetic process GO:0031327 277 0.843
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.802
positive regulation of rna metabolic process GO:0051254 271 0.800
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.788
positive regulation of rna biosynthetic process GO:1902680 266 0.774
positive regulation of transcription dna templated GO:0045893 266 0.761
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.717
negative regulation of rna metabolic process GO:0051253 251 0.679
striated muscle tissue development GO:0014706 27 0.659
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.624
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.576
positive regulation of biosynthetic process GO:0009891 316 0.570
negative regulation of nucleic acid templated transcription GO:1903507 240 0.568
negative regulation of gene expression GO:0010629 387 0.542
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.515
positive regulation of nucleic acid templated transcription GO:1903508 266 0.512
post embryonic appendage morphogenesis GO:0035120 385 0.499
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.492
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.457
negative regulation of rna biosynthetic process GO:1902679 240 0.445
negative regulation of biosynthetic process GO:0009890 277 0.413
muscle cell differentiation GO:0042692 103 0.407
leg disc morphogenesis GO:0007478 80 0.399
negative regulation of cellular metabolic process GO:0031324 382 0.398
cell proliferation GO:0008283 299 0.364
positive regulation of gene expression GO:0010628 290 0.333
imaginal disc derived appendage development GO:0048737 399 0.319
cell death GO:0008219 279 0.318
transcription from rna polymerase ii promoter GO:0006366 368 0.310
positive regulation of cellular biosynthetic process GO:0031328 316 0.294
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.290
muscle structure development GO:0061061 224 0.288
skeletal muscle organ development GO:0060538 48 0.261
locomotory behavior GO:0007626 176 0.250
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.249
muscle tissue development GO:0060537 30 0.236
leg disc development GO:0035218 92 0.202
myoblast proliferation GO:0051450 3 0.196
regulation of cell proliferation GO:0042127 163 0.181
neuron fate commitment GO:0048663 50 0.176
cell motility GO:0048870 251 0.175
negative regulation of neuron death GO:1901215 18 0.169
skeletal muscle tissue development GO:0007519 13 0.160
establishment of localization in cell GO:0051649 402 0.158
positive regulation of macromolecule metabolic process GO:0010604 405 0.152
imaginal disc derived leg morphogenesis GO:0007480 80 0.150
regulation of cell death GO:0010941 173 0.143
muscle tissue morphogenesis GO:0060415 2 0.140
imaginal disc derived appendage morphogenesis GO:0035114 395 0.139
muscle organ development GO:0007517 127 0.133
regulation of cell development GO:0060284 215 0.130
neuron death GO:0070997 27 0.123
eye photoreceptor cell differentiation GO:0001754 145 0.112
blastoderm segmentation GO:0007350 159 0.111
regulation of neuron death GO:1901214 26 0.111
neuroblast development GO:0014019 13 0.110
pigmentation GO:0043473 75 0.108
eye antennal disc development GO:0035214 60 0.108
appendage morphogenesis GO:0035107 397 0.107
appendage development GO:0048736 401 0.098
segmentation GO:0035282 207 0.094
chromatin modification GO:0016568 147 0.092
cell growth GO:0016049 108 0.092
connective tissue development GO:0061448 3 0.091
striated muscle cell differentiation GO:0051146 90 0.085
axonogenesis GO:0007409 290 0.082
antennal development GO:0007469 25 0.082
vesicle organization GO:0016050 44 0.080
regulation of catabolic process GO:0009894 170 0.076
vesicle mediated transport GO:0016192 381 0.076
regulation of cell fate commitment GO:0010453 29 0.075
camera type eye development GO:0043010 4 0.074
endocytosis GO:0006897 310 0.071
organelle localization GO:0051640 148 0.069
macromolecular complex assembly GO:0065003 256 0.068
gland development GO:0048732 191 0.067
secretion by cell GO:0032940 101 0.066
actin filament based process GO:0030029 220 0.064
salivary gland morphogenesis GO:0007435 145 0.061
regulation of hydrolase activity GO:0051336 97 0.061
regulation of molecular function GO:0065009 217 0.061
body morphogenesis GO:0010171 2 0.060
embryo development ending in birth or egg hatching GO:0009792 152 0.060
synaptic transmission GO:0007268 288 0.059
mesenchymal cell development GO:0014031 1 0.058
negative regulation of developmental process GO:0051093 201 0.058
cell migration GO:0016477 238 0.057
organic substance transport GO:0071702 257 0.056
axon development GO:0061564 297 0.056
localization of cell GO:0051674 257 0.056
death GO:0016265 284 0.055
adult locomotory behavior GO:0008344 76 0.053
single organism carbohydrate metabolic process GO:0044723 72 0.053
cell fate determination GO:0001709 91 0.053
tube development GO:0035295 244 0.052
embryonic pattern specification GO:0009880 174 0.051
salivary gland development GO:0007431 162 0.051
positive regulation of molecular function GO:0044093 136 0.049
spinal cord development GO:0021510 1 0.049
protein modification process GO:0036211 438 0.048
regulation of programmed cell death GO:0043067 152 0.048
catabolic process GO:0009056 409 0.047
negative regulation of cellular catabolic process GO:0031330 34 0.047
dendrite guidance GO:0070983 21 0.047
developmental growth GO:0048589 280 0.047
regulation of multicellular organismal development GO:2000026 414 0.047
purine ribonucleotide metabolic process GO:0009150 145 0.046
neuron maturation GO:0042551 31 0.044
compound eye photoreceptor cell differentiation GO:0001751 140 0.044
neuroblast differentiation GO:0014016 29 0.043
signal release GO:0023061 49 0.043
regulation of hormone levels GO:0010817 40 0.043
eye antennal disc morphogenesis GO:0007455 34 0.042
small molecule metabolic process GO:0044281 305 0.041
establishment of organelle localization GO:0051656 122 0.041
growth GO:0040007 359 0.041
tissue morphogenesis GO:0048729 297 0.040
programmed cell death GO:0012501 257 0.040
hair cell differentiation GO:0035315 47 0.039
negative regulation of response to stimulus GO:0048585 258 0.039
carbohydrate metabolic process GO:0005975 82 0.038
regulation of cellular catabolic process GO:0031329 157 0.038
regulation of apoptotic process GO:0042981 130 0.038
neuron fate specification GO:0048665 12 0.037
regulation of system process GO:0044057 36 0.037
non sensory hair organization GO:0035316 47 0.037
regulation of anatomical structure size GO:0090066 163 0.037
dendrite morphogenesis GO:0048813 199 0.036
wound healing GO:0042060 75 0.035
stem cell differentiation GO:0048863 117 0.034
formation of anatomical boundary GO:0048859 37 0.034
cellular macromolecule localization GO:0070727 220 0.034
sex differentiation GO:0007548 81 0.033
circulatory system development GO:0072359 82 0.033
compound eye development GO:0048749 307 0.033
muscle organ morphogenesis GO:0048644 7 0.032
cellular macromolecular complex assembly GO:0034622 153 0.032
cardiovascular system development GO:0072358 82 0.032
somatic muscle development GO:0007525 66 0.032
regulation of cell fate specification GO:0042659 27 0.031
mushroom body development GO:0016319 70 0.031
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.031
organic substance catabolic process GO:1901575 308 0.031
larval development GO:0002164 104 0.031
cell junction organization GO:0034330 57 0.031
neuron projection guidance GO:0097485 241 0.031
defense response GO:0006952 300 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.030
response to ketone GO:1901654 34 0.030
ameboidal type cell migration GO:0001667 151 0.030
embryonic axis specification GO:0000578 107 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
chromatin organization GO:0006325 207 0.029
immune response GO:0006955 246 0.029
flight behavior GO:0007629 26 0.028
regulation of ras gtpase activity GO:0032318 38 0.027
glycosyl compound catabolic process GO:1901658 112 0.027
phagocytosis GO:0006909 215 0.027
response to external biotic stimulus GO:0043207 293 0.026
cellular response to carbohydrate stimulus GO:0071322 4 0.026
chromosome organization GO:0051276 360 0.026
dopamine biosynthetic process GO:0042416 3 0.026
negative regulation of nervous system development GO:0051961 92 0.026
phenol containing compound biosynthetic process GO:0046189 6 0.026
response to extracellular stimulus GO:0009991 116 0.025
compound eye morphogenesis GO:0001745 249 0.025
organic acid metabolic process GO:0006082 103 0.025
regulation of secretion GO:0051046 44 0.025
exocrine system development GO:0035272 162 0.025
ovulation GO:0030728 4 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
cellular protein localization GO:0034613 160 0.024
response to hormone GO:0009725 45 0.023
regulation of catalytic activity GO:0050790 185 0.023
regulation of cell cycle GO:0051726 291 0.023
regeneration GO:0031099 16 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
stem cell division GO:0017145 69 0.023
stem cell development GO:0048864 79 0.023
cytoplasmic transport GO:0016482 130 0.022
catecholamine biosynthetic process GO:0042423 3 0.022
cellular homeostasis GO:0019725 80 0.022
protein transport GO:0015031 155 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
positive regulation of catabolic process GO:0009896 105 0.022
homeostatic process GO:0042592 199 0.022
organophosphate metabolic process GO:0019637 195 0.021
cell cycle arrest GO:0007050 4 0.021
synaptic vesicle localization GO:0097479 53 0.021
regulation of organelle organization GO:0033043 196 0.021
ribonucleotide catabolic process GO:0009261 109 0.020
intracellular transport GO:0046907 228 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
regulation of neuron projection development GO:0010975 69 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
myotube cell development GO:0014904 3 0.020
segment polarity determination GO:0007367 25 0.020
central nervous system development GO:0007417 201 0.020
negative regulation of growth GO:0045926 84 0.020
defense response to gram negative bacterium GO:0050829 94 0.019
tube morphogenesis GO:0035239 191 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
regulation of muscle cell differentiation GO:0051147 8 0.019
hormone secretion GO:0046879 7 0.019
eye development GO:0001654 323 0.019
regulation of muscle organ development GO:0048634 13 0.019
cellular response to mechanical stimulus GO:0071260 2 0.019
regulation of neuron differentiation GO:0045664 103 0.019
dendrite development GO:0016358 204 0.018
cellular response to organic cyclic compound GO:0071407 32 0.018
regulation of r7 cell differentiation GO:0045676 15 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
chemotaxis GO:0006935 249 0.018
somatic stem cell division GO:0048103 37 0.018
negative regulation of neuron apoptotic process GO:0043524 14 0.018
muscle cell fate commitment GO:0042693 14 0.018
catechol containing compound biosynthetic process GO:0009713 3 0.018
wing disc morphogenesis GO:0007472 344 0.017
tissue death GO:0016271 102 0.017
striated muscle cell development GO:0055002 50 0.017
regulation of neurogenesis GO:0050767 158 0.017
endomembrane system organization GO:0010256 119 0.017
brain development GO:0007420 120 0.017
regulation of multi organism process GO:0043900 131 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
actin filament organization GO:0007015 126 0.017
antennal morphogenesis GO:0048800 14 0.017
regulation of striated muscle tissue development GO:0016202 5 0.017
notch signaling pathway GO:0007219 120 0.017
salivary gland histolysis GO:0035070 88 0.016
response to monosaccharide GO:0034284 4 0.016
axon guidance GO:0007411 233 0.016
carbohydrate biosynthetic process GO:0016051 17 0.016
gtp metabolic process GO:0046039 72 0.016
oxidation reduction process GO:0055114 123 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
adult behavior GO:0030534 137 0.016
regulation of immune system process GO:0002682 176 0.016
secretion GO:0046903 109 0.015
single organism catabolic process GO:0044712 228 0.015
regulation of immune response GO:0050776 118 0.015
macromolecule catabolic process GO:0009057 161 0.015
chaeta development GO:0022416 97 0.015
cellular protein complex assembly GO:0043623 71 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
neurological system process GO:0050877 358 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
dorsal ventral axis specification GO:0009950 66 0.015
cellular amide metabolic process GO:0043603 80 0.014
gland morphogenesis GO:0022612 145 0.014
immune system development GO:0002520 57 0.014
positive regulation of transport GO:0051050 92 0.014
kidney development GO:0001822 3 0.014
nephron development GO:0072006 3 0.014
sensory perception of pain GO:0019233 4 0.014
response to wounding GO:0009611 94 0.014
stem cell proliferation GO:0072089 88 0.014
rna localization GO:0006403 115 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
cellular chemical homeostasis GO:0055082 40 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
regulation of cell growth GO:0001558 43 0.014
single organism biosynthetic process GO:0044711 206 0.014
positive regulation of signal transduction GO:0009967 223 0.013
negative regulation of signaling GO:0023057 219 0.013
peptide metabolic process GO:0006518 80 0.013
nucleotide metabolic process GO:0009117 161 0.013
sensory organ morphogenesis GO:0090596 260 0.013
cell type specific apoptotic process GO:0097285 38 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
neural retina development GO:0003407 4 0.013
digestive tract development GO:0048565 149 0.013
cell maturation GO:0048469 144 0.013
cardiocyte differentiation GO:0035051 29 0.013
heart development GO:0007507 82 0.013
immune system process GO:0002376 347 0.012
regulation of nervous system development GO:0051960 248 0.012
retinal cone cell differentiation GO:0042670 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.012
vesicle localization GO:0051648 55 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
neuron apoptotic process GO:0051402 17 0.012
response to lipid GO:0033993 38 0.012
formation of organ boundary GO:0010160 30 0.012
cellular catabolic process GO:0044248 372 0.012
negative regulation of molecular function GO:0044092 51 0.012
neuron remodeling GO:0016322 29 0.012
instar larval development GO:0002168 55 0.012
response to fibroblast growth factor GO:0071774 10 0.012
skeletal muscle fiber development GO:0048741 3 0.012
regulation of cell cycle process GO:0010564 181 0.012
motor neuron axon guidance GO:0008045 58 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
kidney epithelium development GO:0072073 3 0.011
response to alcohol GO:0097305 95 0.011
kidney morphogenesis GO:0060993 3 0.011
eye morphogenesis GO:0048592 260 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of cell differentiation GO:0045595 302 0.011
regulation of secretion by cell GO:1903530 39 0.011
protein localization GO:0008104 284 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
hindbrain development GO:0030902 2 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
establishment of protein localization GO:0045184 163 0.011
negative regulation of developmental growth GO:0048640 64 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
apoptotic process GO:0006915 159 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
negative regulation of cell communication GO:0010648 223 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
embryonic heart tube development GO:0035050 22 0.011
single organism behavior GO:0044708 391 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
regulation of transport GO:0051049 181 0.010
actin filament based movement GO:0030048 26 0.010
protein catabolic process GO:0030163 101 0.010
anterior posterior axis specification GO:0009948 109 0.010
reproductive structure development GO:0048608 74 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
positive regulation of developmental process GO:0051094 143 0.010
anterior posterior pattern specification GO:0009952 136 0.010
multicellular organismal signaling GO:0035637 12 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
positive regulation of protein transport GO:0051222 37 0.010
imaginal disc derived wing hair organization GO:0035317 45 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010

nab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.180
disease of cellular proliferation DOID:14566 0 0.180
organ system cancer DOID:0050686 0 0.104
kidney disease DOID:557 0 0.042
disease of anatomical entity DOID:7 0 0.042
urinary system disease DOID:18 0 0.042
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013
diabetes mellitus DOID:9351 0 0.012
type 2 diabetes mellitus DOID:9352 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012