Drosophila melanogaster

0 known processes

l(1)G0045 (Dmel_CG32763)

lethal (1) G0045

(Aliases: BcDNA:LD21623,CG32763,l(1)G0312,CG4129,Dmel\CG32763)

l(1)G0045 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.221
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.217
positive regulation of rna biosynthetic process GO:1902680 266 0.145
positive regulation of rna metabolic process GO:0051254 271 0.144
positive regulation of biosynthetic process GO:0009891 316 0.118
positive regulation of macromolecule metabolic process GO:0010604 405 0.112
positive regulation of nucleic acid templated transcription GO:1903508 266 0.106
transcription from rna polymerase ii promoter GO:0006366 368 0.105
organonitrogen compound metabolic process GO:1901564 318 0.096
posttranscriptional gene silencing by rna GO:0035194 45 0.096
negative regulation of gene expression GO:0010629 387 0.095
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.094
positive regulation of gene expression GO:0010628 290 0.091
death GO:0016265 284 0.087
positive regulation of transcription dna templated GO:0045893 266 0.082
positive regulation of cellular biosynthetic process GO:0031328 316 0.072
programmed cell death GO:0012501 257 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.063
appendage development GO:0048736 401 0.061
post embryonic appendage morphogenesis GO:0035120 385 0.061
developmental programmed cell death GO:0010623 138 0.060
cell death GO:0008219 279 0.059
gene silencing GO:0016458 138 0.056
appendage morphogenesis GO:0035107 397 0.054
regulation of cellular amine metabolic process GO:0033238 3 0.053
cell maturation GO:0048469 144 0.051
oxoacid metabolic process GO:0043436 103 0.048
wing disc morphogenesis GO:0007472 344 0.047
negative regulation of rna metabolic process GO:0051253 251 0.045
dna metabolic process GO:0006259 227 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
positive regulation of response to stimulus GO:0048584 323 0.042
negative regulation of biosynthetic process GO:0009890 277 0.042
cellular protein modification process GO:0006464 438 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
organic acid metabolic process GO:0006082 103 0.040
establishment of localization in cell GO:0051649 402 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
cellular amino acid metabolic process GO:0006520 61 0.040
response to biotic stimulus GO:0009607 294 0.040
small molecule metabolic process GO:0044281 305 0.039
regulation of multicellular organismal development GO:2000026 414 0.039
regulation of cell proliferation GO:0042127 163 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
negative regulation of transcription dna templated GO:0045892 237 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
regulation of cell cycle phase transition GO:1901987 130 0.037
gland development GO:0048732 191 0.037
regulation of cell death GO:0010941 173 0.037
male gamete generation GO:0048232 201 0.036
negative regulation of cellular metabolic process GO:0031324 382 0.036
histolysis GO:0007559 102 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.035
compound eye morphogenesis GO:0001745 249 0.035
spinal cord development GO:0021510 1 0.035
cellular ketone metabolic process GO:0042180 24 0.035
blastoderm segmentation GO:0007350 159 0.034
protein modification process GO:0036211 438 0.034
immune response GO:0006955 246 0.034
positive regulation of signal transduction GO:0009967 223 0.034
regulation of cellular catabolic process GO:0031329 157 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.033
response to glucose GO:0009749 2 0.033
posttranscriptional regulation of gene expression GO:0010608 145 0.033
cellular amine metabolic process GO:0044106 12 0.032
vesicle mediated transport GO:0016192 381 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
tissue death GO:0016271 102 0.032
microtubule based transport GO:0010970 42 0.032
stem cell differentiation GO:0048863 117 0.032
salivary gland development GO:0007431 162 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
sensory organ morphogenesis GO:0090596 260 0.032
peptide metabolic process GO:0006518 80 0.031
developmental maturation GO:0021700 172 0.031
regulation of protein metabolic process GO:0051246 256 0.031
forebrain development GO:0030900 2 0.031
regulation of cell cycle GO:0051726 291 0.031
cell proliferation GO:0008283 299 0.030
chemical homeostasis GO:0048878 92 0.029
camera type eye development GO:0043010 4 0.029
taxis GO:0042330 304 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
positive regulation of cell communication GO:0010647 250 0.029
cellular response to dna damage stimulus GO:0006974 223 0.028
peptidyl amino acid modification GO:0018193 105 0.028
response to monosaccharide GO:0034284 4 0.028
autophagic cell death GO:0048102 83 0.027
response to external biotic stimulus GO:0043207 293 0.026
cellularization GO:0007349 90 0.026
central nervous system development GO:0007417 201 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
head development GO:0060322 135 0.026
cell projection assembly GO:0030031 94 0.025
actin filament based process GO:0030029 220 0.025
regulation of cellular component size GO:0032535 98 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
proteolysis GO:0006508 192 0.025
spermatogenesis GO:0007283 200 0.025
body morphogenesis GO:0010171 2 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
organelle fission GO:0048285 340 0.025
positive regulation of wnt signaling pathway GO:0030177 25 0.025
regionalization GO:0003002 416 0.024
telencephalon development GO:0021537 2 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
response to abiotic stimulus GO:0009628 341 0.024
growth GO:0040007 359 0.024
negative regulation of mitotic cell cycle GO:0045930 109 0.024
meiotic cell cycle process GO:1903046 132 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
cellular protein catabolic process GO:0044257 83 0.024
salivary gland cell autophagic cell death GO:0035071 83 0.024
embryonic pattern specification GO:0009880 174 0.024
morphogenesis of an epithelium GO:0002009 276 0.023
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
metal ion transport GO:0030001 74 0.023
response to lipopolysaccharide GO:0032496 4 0.023
single organism biosynthetic process GO:0044711 206 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
phagocytosis GO:0006909 215 0.022
positive regulation of signaling GO:0023056 243 0.022
regulation of programmed cell death GO:0043067 152 0.022
regulation of epithelial cell proliferation GO:0050678 4 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
response to other organism GO:0051707 293 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
exocrine system development GO:0035272 162 0.021
peptidyl lysine modification GO:0018205 57 0.021
photoreceptor cell differentiation GO:0046530 170 0.021
mitotic cell cycle phase transition GO:0044772 138 0.021
chromatin modification GO:0016568 147 0.021
response to hexose GO:0009746 3 0.020
eye morphogenesis GO:0048592 260 0.020
cellular response to biotic stimulus GO:0071216 4 0.020
negative regulation of cell death GO:0060548 81 0.020
nuclear division GO:0000280 332 0.020
regulation of cell cycle process GO:0010564 181 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
cytoskeleton dependent intracellular transport GO:0030705 44 0.020
learning or memory GO:0007611 141 0.020
kidney development GO:0001822 3 0.020
dorsal ventral pattern formation GO:0009953 133 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
oocyte construction GO:0007308 112 0.019
stem cell development GO:0048864 79 0.019
protein transmembrane transport GO:0071806 4 0.019
salivary gland histolysis GO:0035070 88 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
kidney morphogenesis GO:0060993 3 0.019
molting cycle chitin based cuticle GO:0007591 56 0.019
mating GO:0007618 120 0.019
organelle localization GO:0051640 148 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
negative regulation of signal transduction GO:0009968 206 0.019
salivary gland morphogenesis GO:0007435 145 0.019
digestive tract development GO:0048565 149 0.019
innate immune response activating signal transduction GO:0002758 2 0.019
limb morphogenesis GO:0035108 1 0.018
defense response GO:0006952 300 0.018
transmembrane transport GO:0055085 139 0.018
stem cell maintenance GO:0019827 67 0.018
mesenchymal cell differentiation GO:0048762 1 0.018
mrna metabolic process GO:0016071 124 0.018
reproductive behavior GO:0019098 122 0.018
regulation of catabolic process GO:0009894 170 0.018
positive regulation of cell death GO:0010942 69 0.018
mitotic cell cycle embryonic GO:0045448 38 0.018
compound eye development GO:0048749 307 0.018
endocytosis GO:0006897 310 0.017
instar larval development GO:0002168 55 0.017
regulation of immune response GO:0050776 118 0.017
photoreceptor cell axon guidance GO:0072499 23 0.017
positive regulation of molecular function GO:0044093 136 0.017
neuron remodeling GO:0016322 29 0.017
immune system process GO:0002376 347 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
tripartite regional subdivision GO:0007351 103 0.017
covalent chromatin modification GO:0016569 106 0.017
photoreceptor cell development GO:0042461 96 0.017
response to wounding GO:0009611 94 0.017
gene silencing by rna GO:0031047 57 0.017
sensory perception of smell GO:0007608 80 0.017
axon guidance GO:0007411 233 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
multi organism behavior GO:0051705 175 0.017
amine metabolic process GO:0009308 12 0.017
convergent extension involved in gastrulation GO:0060027 2 0.017
axis specification GO:0009798 167 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
actomyosin structure organization GO:0031032 56 0.017
spermatid development GO:0007286 98 0.017
chromosome segregation GO:0007059 157 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
regulation of gene expression epigenetic GO:0040029 128 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
response to bacterium GO:0009617 198 0.016
establishment of protein localization GO:0045184 163 0.016
negative regulation of programmed cell death GO:0043069 72 0.016
organic substance catabolic process GO:1901575 308 0.016
neuron maturation GO:0042551 31 0.016
regulation of defense response GO:0031347 102 0.016
regulation of protein modification process GO:0031399 112 0.016
cation homeostasis GO:0055080 51 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
digestive tract morphogenesis GO:0048546 127 0.016
regulation of transcription regulatory region dna binding GO:2000677 3 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
intracellular transport GO:0046907 228 0.016
vesicle localization GO:0051648 55 0.016
mitotic sister chromatid segregation GO:0000070 87 0.016
immune response activating signal transduction GO:0002757 2 0.016
cellular catabolic process GO:0044248 372 0.016
chemotaxis GO:0006935 249 0.015
cation transport GO:0006812 110 0.015
respiratory system development GO:0060541 213 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
segmentation GO:0035282 207 0.015
neuron projection guidance GO:0097485 241 0.015
dorsal ventral axis specification GO:0009950 66 0.015
mitotic spindle organization GO:0007052 220 0.015
regulation of apoptotic process GO:0042981 130 0.015
centrosome organization GO:0051297 163 0.015
regulation of immune system process GO:0002682 176 0.015
mesenchymal cell development GO:0014031 1 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.015
response to ecdysone GO:0035075 34 0.015
smoothened signaling pathway GO:0007224 49 0.015
embryonic axis specification GO:0000578 107 0.015
eye development GO:0001654 323 0.015
rna processing GO:0006396 147 0.015
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.014
sterol homeostasis GO:0055092 4 0.014
protein localization GO:0008104 284 0.014
wnt signaling pathway GO:0016055 98 0.014
cilium morphogenesis GO:0060271 39 0.014
tube morphogenesis GO:0035239 191 0.014
mrna processing GO:0006397 104 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
spermatid differentiation GO:0048515 114 0.014
localization of cell GO:0051674 257 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
cell cycle phase transition GO:0044770 140 0.014
single organism intracellular transport GO:1902582 207 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
gland morphogenesis GO:0022612 145 0.014
nucleotide metabolic process GO:0009117 161 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
intracellular signal transduction GO:0035556 300 0.014
cell division GO:0051301 248 0.014
homeostatic process GO:0042592 199 0.014
catabolic process GO:0009056 409 0.014
dna integrity checkpoint GO:0031570 81 0.014
regulation of molecular function GO:0065009 217 0.014
locomotory behavior GO:0007626 176 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
alternative mrna splicing via spliceosome GO:0000380 60 0.014
activation of innate immune response GO:0002218 4 0.013
hindgut morphogenesis GO:0007442 58 0.013
innate immune response GO:0045087 144 0.013
cellular homeostasis GO:0019725 80 0.013
regulation of catalytic activity GO:0050790 185 0.013
developmental growth GO:0048589 280 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
spindle elongation GO:0051231 83 0.013
protein catabolic process GO:0030163 101 0.013
epithelial cell differentiation GO:0030855 322 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
microtubule based movement GO:0007018 51 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
cell fate specification GO:0001708 71 0.013
multi organism reproductive behavior GO:0044705 121 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
positive regulation of cell migration GO:0030335 2 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
protein transport GO:0015031 155 0.013
regulation of response to stress GO:0080134 200 0.013
macromolecule methylation GO:0043414 45 0.013
oocyte development GO:0048599 124 0.013
positive regulation of apoptotic process GO:0043065 47 0.012
macromolecule catabolic process GO:0009057 161 0.012
dorsal closure GO:0007391 79 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
regulation of organelle organization GO:0033043 196 0.012
actin filament organization GO:0007015 126 0.012
striated muscle cell development GO:0055002 50 0.012
transition metal ion homeostasis GO:0055076 17 0.012
positive regulation of proteolysis GO:0045862 52 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
negative regulation of developmental process GO:0051093 201 0.012
organophosphate metabolic process GO:0019637 195 0.012
brain development GO:0007420 120 0.012
single organism behavior GO:0044708 391 0.012
ion transport GO:0006811 145 0.012
antimicrobial humoral response GO:0019730 99 0.012
axon cargo transport GO:0008088 29 0.012
sister chromatid segregation GO:0000819 92 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
endoderm formation GO:0001706 3 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.012
metal ion homeostasis GO:0055065 44 0.012
molting cycle process GO:0022404 29 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
cognition GO:0050890 141 0.012
cellular macromolecule localization GO:0070727 220 0.012
muscle structure development GO:0061061 224 0.012
neurological system process GO:0050877 358 0.012
anterior posterior axis specification GO:0009948 109 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
regulation of peptidase activity GO:0052547 39 0.012
axonogenesis GO:0007409 290 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
cellular protein localization GO:0034613 160 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
response to sterol GO:0036314 34 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
hindbrain development GO:0030902 2 0.012
protein hydroxylation GO:0018126 1 0.012
regulation of cell cycle g1 s phase transition GO:1902806 23 0.012
limb development GO:0060173 1 0.011
regulation of mrna processing GO:0050684 71 0.011
nephron epithelium morphogenesis GO:0072088 3 0.011
chromatin organization GO:0006325 207 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
embryonic morphogenesis GO:0048598 206 0.011
notch signaling pathway GO:0007219 120 0.011
muscle organ development GO:0007517 127 0.011
regulation of localization GO:0032879 275 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
positive regulation of cell motility GO:2000147 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
response to organic substance GO:0010033 284 0.011
organic substance transport GO:0071702 257 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
rhabdomere development GO:0042052 38 0.011
rna localization GO:0006403 115 0.011
cellular response to organic substance GO:0071310 132 0.011
regulation of cellular response to stress GO:0080135 89 0.011
regulation of anatomical structure size GO:0090066 163 0.011
oocyte axis specification GO:0007309 108 0.011
cellular response to radiation GO:0071478 52 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
cellular chemical homeostasis GO:0055082 40 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
dna replication GO:0006260 48 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
leg disc morphogenesis GO:0007478 80 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
establishment of vesicle localization GO:0051650 51 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
synaptic vesicle transport GO:0048489 50 0.011
response to organophosphorus GO:0046683 2 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
tor signaling GO:0031929 32 0.010
cellular amide metabolic process GO:0043603 80 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
skeletal muscle fiber development GO:0048741 3 0.010
regulation of gene silencing GO:0060968 63 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
actin cytoskeleton organization GO:0030036 206 0.010
regulation of embryonic cell shape GO:0016476 30 0.010
translation GO:0006412 69 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
rna interference GO:0016246 27 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
heterocycle catabolic process GO:0046700 166 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
synaptic vesicle localization GO:0097479 53 0.010
positive regulation of catabolic process GO:0009896 105 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
cell cycle dna replication GO:0044786 23 0.010
chromatin silencing GO:0006342 76 0.010
regulation of meiosis GO:0040020 3 0.010
negative regulation of organelle organization GO:0010639 56 0.010
dendrite morphogenesis GO:0048813 199 0.010
immune response regulating signaling pathway GO:0002764 2 0.010

l(1)G0045 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
cardiovascular system disease DOID:1287 0 0.014
nervous system disease DOID:863 0 0.014