Drosophila melanogaster

174 known processes

Rbf (Dmel_CG7413)

Retinoblastoma-family protein

(Aliases: Rb1,Rbf1,rb,rbf1,pRb,dRBF,EG:34F3.3,Dmel\CG7413,FBF,Rb,RbF,RBF,RBF1,CG7413,rbf)

Rbf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.998
regulation of cell cycle g1 s phase transition GO:1902806 23 0.969
ovarian follicle cell development GO:0030707 248 0.961
cell cycle phase transition GO:0044770 140 0.949
chromosome organization GO:0051276 360 0.949
g1 s transition of mitotic cell cycle GO:0000082 31 0.929
apoptotic signaling pathway GO:0097190 27 0.912
defense response to other organism GO:0098542 225 0.907
regulation of nurse cell apoptotic process GO:0045477 9 0.906
response to abiotic stimulus GO:0009628 341 0.872
columnar cuboidal epithelial cell development GO:0002066 249 0.870
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.865
protein modification process GO:0036211 438 0.859
cellular response to dna damage stimulus GO:0006974 223 0.857
epithelial cell differentiation GO:0030855 322 0.854
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.853
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.847
eggshell chorion gene amplification GO:0007307 9 0.844
mitotic nuclear division GO:0007067 213 0.835
regulation of cell cycle process GO:0010564 181 0.826
regulation of mitotic cell cycle GO:0007346 190 0.822
positive regulation of macromolecule metabolic process GO:0010604 405 0.821
negative regulation of transcription dna templated GO:0045892 237 0.818
embryo development ending in birth or egg hatching GO:0009792 152 0.817
Worm
regulation of cell death GO:0010941 173 0.809
cell division GO:0051301 248 0.802
epithelial cell development GO:0002064 274 0.799
organelle fission GO:0048285 340 0.795
programmed cell death GO:0012501 257 0.792
cellular protein modification process GO:0006464 438 0.782
regulation of programmed cell death GO:0043067 152 0.782
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.781
negative regulation of biosynthetic process GO:0009890 277 0.772
regulation of dna metabolic process GO:0051052 34 0.769
morphogenesis of an epithelium GO:0002009 276 0.767
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.762
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.758
positive regulation of rna metabolic process GO:0051254 271 0.754
reproductive behavior GO:0019098 122 0.754
Worm
regulation of cell cycle GO:0051726 291 0.753
negative regulation of rna metabolic process GO:0051253 251 0.730
negative regulation of nucleic acid templated transcription GO:1903507 240 0.721
response to biotic stimulus GO:0009607 294 0.719
intrinsic apoptotic signaling pathway GO:0097193 16 0.713
chromosome segregation GO:0007059 157 0.709
cell proliferation GO:0008283 299 0.708
regulation of mitosis GO:0007088 56 0.700
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.676
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.666
death GO:0016265 284 0.665
dna amplification GO:0006277 11 0.655
cell cycle g1 s phase transition GO:0044843 31 0.641
nuclear division GO:0000280 332 0.641
positive regulation of cellular biosynthetic process GO:0031328 316 0.607
cell cycle dna replication GO:0044786 23 0.600
positive regulation of transcription dna templated GO:0045893 266 0.588
chromatin assembly GO:0031497 48 0.588
multicellular organismal reproductive behavior GO:0033057 110 0.578
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.575
negative regulation of gene expression GO:0010629 387 0.560
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.559
negative regulation of cellular biosynthetic process GO:0031327 277 0.549
regulation of multicellular organismal development GO:2000026 414 0.543
Worm
chromatin organization GO:0006325 207 0.522
negative regulation of apoptotic process GO:0043066 63 0.500
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.498
dna conformation change GO:0071103 105 0.484
tissue morphogenesis GO:0048729 297 0.461
positive regulation of nucleic acid templated transcription GO:1903508 266 0.456
apoptotic process GO:0006915 159 0.453
regulation of canonical wnt signaling pathway GO:0060828 15 0.450
regulation of mitotic cell cycle phase transition GO:1901990 130 0.443
protein complex biogenesis GO:0070271 201 0.435
dendrite morphogenesis GO:0048813 199 0.424
multi organism behavior GO:0051705 175 0.407
Worm
regulation of cell cycle phase transition GO:1901987 130 0.404
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.399
negative regulation of rna biosynthetic process GO:1902679 240 0.392
regulation of cell development GO:0060284 215 0.390
actomyosin contractile ring assembly GO:0000915 10 0.387
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.379
regulation of apoptotic process GO:0042981 130 0.374
regulation of cell proliferation GO:0042127 163 0.373
positive regulation of gene expression GO:0010628 290 0.357
protein localization to chromatin GO:0071168 3 0.356
regulation of cell differentiation GO:0045595 302 0.343
sensory organ precursor cell division GO:0045035 10 0.337
reproductive system development GO:0061458 74 0.326
spermatogenesis GO:0007283 200 0.319
cellular macromolecule localization GO:0070727 220 0.311
negative regulation of mitotic cell cycle GO:0045930 109 0.310
reproductive structure development GO:0048608 74 0.308
protein complex assembly GO:0006461 200 0.306
response to radiation GO:0009314 155 0.303
oocyte development GO:0048599 124 0.300
axon guidance GO:0007411 233 0.291
anterior posterior pattern specification GO:0009952 136 0.289
mitotic cell cycle phase transition GO:0044772 138 0.288
segmentation GO:0035282 207 0.285
positive regulation of programmed cell death GO:0043068 62 0.279
compound eye morphogenesis GO:0001745 249 0.276
eggshell formation GO:0030703 105 0.276
appendage morphogenesis GO:0035107 397 0.276
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.271
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.268
cell death GO:0008219 279 0.266
positive regulation of cell death GO:0010942 69 0.256
sex differentiation GO:0007548 81 0.255
intracellular transport GO:0046907 228 0.253
response to external biotic stimulus GO:0043207 293 0.251
negative regulation of programmed cell death GO:0043069 72 0.246
negative regulation of cell death GO:0060548 81 0.243
regulation of wnt signaling pathway GO:0030111 68 0.242
imaginal disc derived leg morphogenesis GO:0007480 80 0.241
eggshell chorion assembly GO:0007306 66 0.240
regulation of catalytic activity GO:0050790 185 0.233
Human
oocyte differentiation GO:0009994 145 0.232
digestive system development GO:0055123 149 0.229
Worm
wing disc morphogenesis GO:0007472 344 0.228
nuclear dna replication GO:0033260 1 0.219
regulation of gene expression epigenetic GO:0040029 128 0.219
regulation of cellular catabolic process GO:0031329 157 0.217
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.210
larval development GO:0002164 104 0.205
Worm
gonad development GO:0008406 50 0.188
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.187
leg disc morphogenesis GO:0007478 80 0.185
appendage development GO:0048736 401 0.185
response to light stimulus GO:0009416 124 0.183
cellular response to chemical stimulus GO:0070887 199 0.181
wnt signaling pathway GO:0016055 98 0.176
regulation of sister chromatid cohesion GO:0007063 2 0.176
positive regulation of nurse cell apoptotic process GO:0045850 5 0.174
developmental maturation GO:0021700 172 0.172
protein localization GO:0008104 284 0.168
nucleosome organization GO:0034728 59 0.167
germarium derived female germ line cyst formation GO:0030727 42 0.166
cell maturation GO:0048469 144 0.166
positive regulation of reproductive process GO:2000243 7 0.165
macromolecular complex assembly GO:0065003 256 0.164
developmental programmed cell death GO:0010623 138 0.162
vesicle mediated transport GO:0016192 381 0.162
positive regulation of biosynthetic process GO:0009891 316 0.161
regulation of molecular function GO:0065009 217 0.159
oocyte construction GO:0007308 112 0.156
single organism biosynthetic process GO:0044711 206 0.155
regulation of organelle organization GO:0033043 196 0.150
positive regulation of cell proliferation GO:0008284 47 0.147
cellular catabolic process GO:0044248 372 0.145
organic substance catabolic process GO:1901575 308 0.142
positive regulation of developmental process GO:0051094 143 0.140
Worm
positive regulation of apoptotic process GO:0043065 47 0.139
negative regulation of response to stimulus GO:0048585 258 0.139
peptidyl amino acid modification GO:0018193 105 0.139
immune system process GO:0002376 347 0.139
negative regulation of wnt signaling pathway GO:0030178 28 0.138
defense response to bacterium GO:0042742 178 0.136
response to other organism GO:0051707 293 0.135
oocyte anterior posterior axis specification GO:0007314 72 0.133
meiotic nuclear division GO:0007126 151 0.133
negative regulation of cell cycle process GO:0010948 109 0.132
development of primary sexual characteristics GO:0045137 50 0.130
axon development GO:0061564 297 0.130
muscle tissue development GO:0060537 30 0.128
regulation of cytoskeleton organization GO:0051493 89 0.128
eye development GO:0001654 323 0.120
protein modification by small protein conjugation or removal GO:0070647 106 0.119
negative regulation of signaling GO:0023057 219 0.118
regulation of cell division GO:0051302 72 0.117
chromatin assembly or disassembly GO:0006333 52 0.117
meiotic cell cycle GO:0051321 171 0.116
negative regulation of cell cycle phase transition GO:1901988 103 0.116
ribose phosphate metabolic process GO:0019693 145 0.116
negative regulation of cell cycle GO:0045786 116 0.116
negative regulation of dna replication GO:0008156 7 0.114
post embryonic appendage morphogenesis GO:0035120 385 0.112
regulation of localization GO:0032879 275 0.110
sensory organ morphogenesis GO:0090596 260 0.110
posttranscriptional gene silencing by rna GO:0035194 45 0.109
gene silencing GO:0016458 138 0.105
endocytosis GO:0006897 310 0.105
embryonic pattern specification GO:0009880 174 0.103
posttranscriptional gene silencing GO:0016441 46 0.102
chromatin modification GO:0016568 147 0.102
cellular protein localization GO:0034613 160 0.102
oocyte maturation GO:0001556 3 0.101
nucleocytoplasmic transport GO:0006913 72 0.100
dna integrity checkpoint GO:0031570 81 0.100
compound eye development GO:0048749 307 0.099
positive regulation of rna biosynthetic process GO:1902680 266 0.099
muscle organ development GO:0007517 127 0.099
regulation of nuclear division GO:0051783 58 0.097
regulation of kinase activity GO:0043549 53 0.097
Human
regulation of neurogenesis GO:0050767 158 0.094
response to oxygen containing compound GO:1901700 200 0.094
positive regulation of mitotic cell cycle GO:0045931 34 0.093
regulation of nervous system development GO:0051960 248 0.093
negative regulation of canonical wnt signaling pathway GO:0090090 6 0.093
immune response GO:0006955 246 0.092
positive regulation of protein metabolic process GO:0051247 128 0.092
negative regulation of cell differentiation GO:0045596 143 0.092
enzyme linked receptor protein signaling pathway GO:0007167 179 0.091
dna biosynthetic process GO:0071897 24 0.091
centrosome cycle GO:0007098 137 0.091
dna replication GO:0006260 48 0.088
pole plasm assembly GO:0007315 61 0.087
negative regulation of developmental process GO:0051093 201 0.084
Worm
equator specification GO:0045317 4 0.083
regulation of stem cell proliferation GO:0072091 40 0.083
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.082
lipid metabolic process GO:0006629 121 0.082
Human
genitalia development GO:0048806 26 0.082
organic substance transport GO:0071702 257 0.082
glial cell differentiation GO:0010001 35 0.080
appendage segmentation GO:0035285 26 0.080
negative regulation of gene expression epigenetic GO:0045814 77 0.079
eye morphogenesis GO:0048592 260 0.079
homeostatic process GO:0042592 199 0.078
regulation of chromosome segregation GO:0051983 32 0.077
regulation of cellular localization GO:0060341 136 0.077
organonitrogen compound metabolic process GO:1901564 318 0.077
regulation of growth GO:0040008 233 0.077
Worm
molting cycle chitin based cuticle GO:0007591 56 0.076
synaptic transmission GO:0007268 288 0.076
cell cycle checkpoint GO:0000075 95 0.074
notch signaling pathway GO:0007219 120 0.073
covalent chromatin modification GO:0016569 106 0.073
regulation of organ growth GO:0046620 42 0.072
growth GO:0040007 359 0.071
Worm
neuron projection guidance GO:0097485 241 0.070
methylation GO:0032259 47 0.069
positive regulation of cellular protein metabolic process GO:0032270 118 0.068
response to alcohol GO:0097305 95 0.068
catabolic process GO:0009056 409 0.068
gene silencing by rna GO:0031047 57 0.067
male gamete generation GO:0048232 201 0.067
negative regulation of cell proliferation GO:0008285 69 0.067
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.066
regulation of synaptic transmission GO:0050804 69 0.066
chorion containing eggshell formation GO:0007304 105 0.066
purine nucleotide metabolic process GO:0006163 146 0.065
histone modification GO:0016570 106 0.064
leg disc development GO:0035218 92 0.064
imaginal disc derived appendage morphogenesis GO:0035114 395 0.064
protein catabolic process GO:0030163 101 0.063
membrane organization GO:0061024 112 0.063
multi organism reproductive behavior GO:0044705 121 0.062
Worm
dendrite development GO:0016358 204 0.061
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.061
purine containing compound catabolic process GO:0072523 112 0.061
negative regulation of neuroblast proliferation GO:0007406 27 0.061
proteolysis GO:0006508 192 0.060
positive regulation of catalytic activity GO:0043085 118 0.060
cellular macromolecular complex assembly GO:0034622 153 0.059
mitotic g2 m transition checkpoint GO:0044818 70 0.059
peptidyl lysine modification GO:0018205 57 0.058
dna packaging GO:0006323 91 0.058
regulation of transport GO:0051049 181 0.057
regulation of mitotic sister chromatid segregation GO:0033047 28 0.057
positive regulation of multicellular organismal process GO:0051240 143 0.057
Worm
regulation of developmental growth GO:0048638 174 0.056
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.056
posttranscriptional regulation of gene expression GO:0010608 145 0.056
cytokinesis GO:0000910 90 0.056
epidermis development GO:0008544 65 0.055
stem cell proliferation GO:0072089 88 0.055
protein targeting to nucleus GO:0044744 51 0.053
regulation of transferase activity GO:0051338 58 0.053
Human
germarium derived egg chamber formation GO:0007293 101 0.053
chromosome separation GO:0051304 42 0.052
organophosphate metabolic process GO:0019637 195 0.051
nucleus organization GO:0006997 45 0.051
modification dependent macromolecule catabolic process GO:0043632 79 0.050
photoreceptor cell differentiation GO:0046530 170 0.050
cellular nitrogen compound catabolic process GO:0044270 165 0.050
cellular response to ethanol GO:0071361 4 0.049
regulation of reproductive process GO:2000241 54 0.048
purine containing compound metabolic process GO:0072521 155 0.048
eye photoreceptor cell fate commitment GO:0042706 37 0.047
nuclear transport GO:0051169 72 0.047
limb morphogenesis GO:0035108 1 0.046
chromatin silencing GO:0006342 76 0.046
single organism cellular localization GO:1902580 180 0.046
modification dependent protein catabolic process GO:0019941 78 0.046
rna localization GO:0006403 115 0.044
digestive tract development GO:0048565 149 0.044
Worm
organophosphate biosynthetic process GO:0090407 46 0.044
protein transport GO:0015031 155 0.044
cellular response to sterol depletion GO:0071501 3 0.043
meiotic cell cycle process GO:1903046 132 0.043
organ growth GO:0035265 56 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
Human
oocyte microtubule cytoskeleton organization GO:0016325 35 0.043
blastoderm segmentation GO:0007350 159 0.043
purine ribonucleotide metabolic process GO:0009150 145 0.042
negative regulation of cell communication GO:0010648 223 0.042
regulation of cell morphogenesis GO:0022604 163 0.042
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.042
female germ line cyst formation GO:0048135 42 0.041
g2 m transition of mitotic cell cycle GO:0000086 19 0.041
defense response to gram negative bacterium GO:0050829 94 0.041
apoptotic process involved in development GO:1902742 20 0.041
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.040
imaginal disc derived leg segmentation GO:0036011 26 0.040
regulation of epithelial cell differentiation GO:0030856 4 0.040
response to organic substance GO:0010033 284 0.040
ubiquitin dependent protein catabolic process GO:0006511 78 0.040
nucleotide metabolic process GO:0009117 161 0.039
imaginal disc derived wing morphogenesis GO:0007476 337 0.039
single organism intracellular transport GO:1902582 207 0.039
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.038
positive regulation of cellular catabolic process GO:0031331 95 0.038
positive regulation of protein deacetylation GO:0090312 2 0.038
regulation of apoptotic signaling pathway GO:2001233 10 0.038
dorsal closure GO:0007391 79 0.037
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 5 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
stem cell maintenance GO:0019827 67 0.036
axis specification GO:0009798 167 0.036
protein phosphorylation GO:0006468 169 0.036
regulation of immune system process GO:0002682 176 0.036
regulation of anatomical structure morphogenesis GO:0022603 242 0.036
cellular component assembly involved in morphogenesis GO:0010927 151 0.036
mitotic sister chromatid segregation GO:0000070 87 0.036
dna damage checkpoint GO:0000077 78 0.035
regulation of cellular component biogenesis GO:0044087 201 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
regulation of notch signaling pathway GO:0008593 100 0.035
germ line cyst formation GO:0048134 44 0.034
sister chromatid segregation GO:0000819 92 0.034
spermatid development GO:0007286 98 0.034
dna replication initiation GO:0006270 6 0.033
negative regulation of notch signaling pathway GO:0045746 41 0.033
single organism catabolic process GO:0044712 228 0.033
germarium derived oocyte fate determination GO:0007294 26 0.033
axonogenesis GO:0007409 290 0.033
regulation of cell growth GO:0001558 43 0.032
regulation of cellular protein metabolic process GO:0032268 243 0.032
protein import into nucleus GO:0006606 51 0.032
regulation of mitotic sister chromatid separation GO:0010965 28 0.032
positive regulation of molecular function GO:0044093 136 0.032
defense response GO:0006952 300 0.032
regulation of neural precursor cell proliferation GO:2000177 35 0.031
oocyte axis specification GO:0007309 108 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
secretion by cell GO:0032940 101 0.030
negative regulation of meiotic cell cycle GO:0051447 2 0.030
cellular response to organic substance GO:0071310 132 0.030
response to ionizing radiation GO:0010212 32 0.030
mitotic dna integrity checkpoint GO:0044774 75 0.030
cell growth GO:0016049 108 0.030
response to inorganic substance GO:0010035 44 0.030
nucleosome assembly GO:0006334 35 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.030
phagocytosis GO:0006909 215 0.030
positive regulation of signal transduction GO:0009967 223 0.030
nucleoside triphosphate catabolic process GO:0009143 108 0.029
muscle structure development GO:0061061 224 0.029
mitotic spindle organization GO:0007052 220 0.029
positive regulation of protein modification process GO:0031401 58 0.029
cell motility GO:0048870 251 0.029
regulation of sister chromatid segregation GO:0033045 28 0.028
protein alkylation GO:0008213 43 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
Human
striated muscle tissue development GO:0014706 27 0.028
positive regulation of cell cycle phase transition GO:1901989 20 0.028
ribonucleotide metabolic process GO:0009259 145 0.027
dna recombination GO:0006310 32 0.027
negative regulation of immune system process GO:0002683 50 0.027
protein localization to organelle GO:0033365 82 0.027
camera type eye morphogenesis GO:0048593 2 0.027
regulation of protein modification process GO:0031399 112 0.027
body morphogenesis GO:0010171 2 0.027
Worm
anatomical structure homeostasis GO:0060249 97 0.027
regulation of innate immune response GO:0045088 71 0.027
proteasomal protein catabolic process GO:0010498 59 0.026
gonad morphogenesis GO:0035262 7 0.026
positive regulation of signaling GO:0023056 243 0.026
regulation of cellular response to stress GO:0080135 89 0.026
response to bacterium GO:0009617 198 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 1 0.026
negative regulation of stem cell proliferation GO:2000647 30 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
stem cell differentiation GO:0048863 117 0.025
canonical wnt signaling pathway GO:0060070 21 0.025
embryonic organ development GO:0048568 50 0.024
Worm
response to temperature stimulus GO:0009266 106 0.024
protein localization to nucleus GO:0034504 55 0.024
cellular response to endogenous stimulus GO:0071495 80 0.024
metaphase anaphase transition of cell cycle GO:0044784 28 0.024
developmental growth GO:0048589 280 0.024
Worm
chromatin remodeling GO:0006338 72 0.024
camera type eye development GO:0043010 4 0.024
macromolecule catabolic process GO:0009057 161 0.024
anterior posterior axis specification GO:0009948 109 0.024
negative regulation of growth GO:0045926 84 0.023
positive regulation of cell cycle process GO:0090068 28 0.023
positive regulation of cell development GO:0010720 61 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
pole plasm mrna localization GO:0019094 49 0.023
purine nucleotide catabolic process GO:0006195 109 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
regulation of protein phosphorylation GO:0001932 64 0.022
embryonic morphogenesis GO:0048598 206 0.022
Worm
intracellular signal transduction GO:0035556 300 0.022
meiotic cell cycle phase transition GO:0044771 4 0.022
embryonic development via the syncytial blastoderm GO:0001700 148 0.022
ribonucleoprotein complex subunit organization GO:0071826 28 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
Worm
positive regulation of cell differentiation GO:0045597 64 0.021
regulation of defense response to virus by host GO:0050691 10 0.021
striated muscle cell differentiation GO:0051146 90 0.021
regulation of protein metabolic process GO:0051246 256 0.021
positive regulation of catabolic process GO:0009896 105 0.021
single organism nuclear import GO:1902593 51 0.021
periodic partitioning GO:0007365 29 0.021
cellular lipid metabolic process GO:0044255 83 0.021
Human
spindle organization GO:0007051 253 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
stem cell fate determination GO:0048867 15 0.021
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.020
positive regulation of apoptotic signaling pathway GO:2001235 4 0.020
negative regulation of dendrite morphogenesis GO:0050774 2 0.020
stem cell development GO:0048864 79 0.020
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.020
ribonucleoside catabolic process GO:0042454 112 0.020
regionalization GO:0003002 416 0.019
multi multicellular organism process GO:0044706 123 0.019
Worm
cellular response to hypoxia GO:0071456 28 0.019
pole plasm rna localization GO:0007316 52 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
connective tissue development GO:0061448 3 0.019
embryonic digestive tract development GO:0048566 5 0.019
Worm
purine ribonucleotide catabolic process GO:0009154 109 0.019
dna methylation GO:0006306 4 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
regulation of protein localization GO:0032880 76 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
nucleoside catabolic process GO:0009164 112 0.019
pigmentation GO:0043473 75 0.018
cellular protein catabolic process GO:0044257 83 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
internal peptidyl lysine acetylation GO:0018393 38 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
negative regulation of imaginal disc growth GO:0045571 8 0.018
peptidyl lysine methylation GO:0018022 16 0.018
negative regulation of transferase activity GO:0051348 18 0.018
compound eye photoreceptor development GO:0042051 78 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
negative regulation of signal transduction GO:0009968 206 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
regulation of multi organism process GO:0043900 131 0.017
protein methylation GO:0006479 43 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of multi organism process GO:0043902 40 0.017
regulation of imaginal disc growth GO:0045570 26 0.017
regulation of phosphatase activity GO:0010921 3 0.017
molting cycle process GO:0022404 29 0.017
positive regulation of proteolysis GO:0045862 52 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
determination of adult lifespan GO:0008340 137 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
dna endoreduplication GO:0042023 22 0.017
cell migration GO:0016477 238 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
negative regulation of dna metabolic process GO:0051053 12 0.016
regulation of dendrite development GO:0050773 37 0.016
establishment of localization in cell GO:0051649 402 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.016
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
small molecule metabolic process GO:0044281 305 0.016
cell fate determination GO:0001709 91 0.016
dsrna fragmentation GO:0031050 15 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.016
production of small rna involved in gene silencing by rna GO:0070918 15 0.016
taxis GO:0042330 304 0.015
glial cell fate determination GO:0007403 3 0.015
regulation of microtubule based process GO:0032886 49 0.015
fatty acid homeostasis GO:0055089 2 0.015
organophosphate catabolic process GO:0046434 112 0.015
eye photoreceptor cell development GO:0042462 81 0.015
centrosome organization GO:0051297 163 0.015
ion transport GO:0006811 145 0.015
regulation of gtp catabolic process GO:0033124 44 0.015

Rbf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.328
cancer DOID:162 0 0.210
organ system cancer DOID:0050686 0 0.210
musculoskeletal system cancer DOID:0060100 0 0.018
connective tissue cancer DOID:201 0 0.018