Drosophila melanogaster

41 known processes

ort (Dmel_CG7411)

ora transientless

(Aliases: HisCl,hisCl2,DmHisCl2,GluCI,Hist1,Ort,Dm-hclA,Dmel\CG7411,hclA,HisCI2,DMHisClalpha1,HisCl2,ora,CG7411)

ort biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.855
Fly
sensory perception GO:0007600 196 0.806
adult behavior GO:0030534 137 0.747
synaptic transmission GO:0007268 288 0.375
ion transmembrane transport GO:0034220 122 0.280
response to toxic substance GO:0009636 22 0.275
sensory perception of light stimulus GO:0050953 12 0.246
response to abiotic stimulus GO:0009628 341 0.193
ion transport GO:0006811 145 0.192
single organism behavior GO:0044708 391 0.181
cognition GO:0050890 141 0.149
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.137
developmental pigmentation GO:0048066 68 0.131
death GO:0016265 284 0.129
detection of stimulus GO:0051606 156 0.113
response to organic substance GO:0010033 284 0.110
oxoacid metabolic process GO:0043436 103 0.106
detection of external stimulus GO:0009581 66 0.101
response to oxygen containing compound GO:1901700 200 0.100
locomotory behavior GO:0007626 176 0.099
learning or memory GO:0007611 141 0.088
Fly
adult locomotory behavior GO:0008344 76 0.087
positive regulation of signaling GO:0023056 243 0.084
blood circulation GO:0008015 26 0.083
multi multicellular organism process GO:0044706 123 0.077
cellular ketone metabolic process GO:0042180 24 0.075
apoptotic process GO:0006915 159 0.075
small molecule metabolic process GO:0044281 305 0.074
intracellular signal transduction GO:0035556 300 0.070
sensory perception of smell GO:0007608 80 0.069
cation transport GO:0006812 110 0.066
cellular lipid metabolic process GO:0044255 83 0.065
sensory perception of chemical stimulus GO:0007606 116 0.065
response to light stimulus GO:0009416 124 0.064
purine ribonucleoside metabolic process GO:0046128 127 0.062
pigmentation GO:0043473 75 0.061
visual perception GO:0007601 9 0.060
eye morphogenesis GO:0048592 260 0.060
detection of abiotic stimulus GO:0009582 66 0.060
detection of light stimulus GO:0009583 58 0.059
photoreceptor cell differentiation GO:0046530 170 0.057
photoreceptor cell development GO:0042461 96 0.056
cellular response to chemical stimulus GO:0070887 199 0.055
oxidation reduction process GO:0055114 123 0.055
positive regulation of cell communication GO:0010647 250 0.052
anion homeostasis GO:0055081 3 0.052
organic hydroxy compound metabolic process GO:1901615 83 0.052
thermotaxis GO:0043052 16 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
detection of visible light GO:0009584 38 0.049
regulation of localization GO:0032879 275 0.048
metal ion transport GO:0030001 74 0.048
cell death GO:0008219 279 0.047
positive regulation of catabolic process GO:0009896 105 0.046
cellular cation homeostasis GO:0030003 38 0.045
catabolic process GO:0009056 409 0.045
amine metabolic process GO:0009308 12 0.043
g protein coupled receptor signaling pathway GO:0007186 136 0.043
response to organophosphorus GO:0046683 2 0.042
programmed cell death GO:0012501 257 0.042
purine nucleotide metabolic process GO:0006163 146 0.040
cuticle development GO:0042335 86 0.040
endocytosis GO:0006897 310 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
organic substance catabolic process GO:1901575 308 0.038
regulation of intracellular signal transduction GO:1902531 236 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
transmembrane transport GO:0055085 139 0.037
response to temperature stimulus GO:0009266 106 0.037
purine nucleoside triphosphate catabolic process GO:0009146 108 0.036
cation transmembrane transport GO:0098655 88 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.034
cellular response to carbohydrate stimulus GO:0071322 4 0.034
aromatic compound catabolic process GO:0019439 166 0.034
chemotaxis GO:0006935 249 0.033
organonitrogen compound metabolic process GO:1901564 318 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.031
regulation of cell differentiation GO:0045595 302 0.031
regulation of apoptotic process GO:0042981 130 0.030
defense response GO:0006952 300 0.030
dna metabolic process GO:0006259 227 0.030
single organism biosynthetic process GO:0044711 206 0.030
taxis GO:0042330 304 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.030
divalent metal ion transport GO:0070838 26 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
immune response regulating signaling pathway GO:0002764 2 0.029
immune system process GO:0002376 347 0.029
positive regulation of signal transduction GO:0009967 223 0.028
cellular catabolic process GO:0044248 372 0.028
negative regulation of cell communication GO:0010648 223 0.028
Fly
regulation of epithelial cell proliferation GO:0050678 4 0.027
organophosphate metabolic process GO:0019637 195 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
lipid metabolic process GO:0006629 121 0.027
vitamin biosynthetic process GO:0009110 1 0.027
regulation of cell death GO:0010941 173 0.026
isoprenoid metabolic process GO:0006720 8 0.026
purine containing compound catabolic process GO:0072523 112 0.026
fat soluble vitamin metabolic process GO:0006775 1 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
negative regulation of signaling GO:0023057 219 0.026
Fly
neuromuscular junction development GO:0007528 149 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
neuron recognition GO:0008038 101 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
regulation of secretion by cell GO:1903530 39 0.025
regulation of cellular component biogenesis GO:0044087 201 0.024
growth GO:0040007 359 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
positive regulation of nucleoside metabolic process GO:0045979 47 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
eye development GO:0001654 323 0.024
nucleoside metabolic process GO:0009116 127 0.023
membrane depolarization GO:0051899 4 0.023
vesicle mediated transport GO:0016192 381 0.023
regulation of catabolic process GO:0009894 170 0.023
compound eye photoreceptor development GO:0042051 78 0.022
sleep GO:0030431 49 0.022
Fly
establishment of localization in cell GO:0051649 402 0.022
terpenoid metabolic process GO:0006721 7 0.021
regulation of multi organism process GO:0043900 131 0.021
immune response activating signal transduction GO:0002757 2 0.021
fat soluble vitamin biosynthetic process GO:0042362 1 0.021
cellular response to organonitrogen compound GO:0071417 36 0.021
signal release GO:0023061 49 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
cellular response to insulin stimulus GO:0032869 28 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
negative regulation of gene expression GO:0010629 387 0.020
negative regulation of developmental process GO:0051093 201 0.020
purine nucleoside metabolic process GO:0042278 127 0.020
immune response GO:0006955 246 0.020
developmental growth GO:0048589 280 0.020
regulation of anatomical structure size GO:0090066 163 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
positive regulation of gene expression GO:0010628 290 0.020
response to radiation GO:0009314 155 0.019
sensory perception of sound GO:0007605 56 0.019
gene silencing GO:0016458 138 0.019
compound eye development GO:0048749 307 0.019
regulation of retinal cell programmed cell death GO:0046668 18 0.019
response to heat GO:0009408 63 0.019
regulation of hormone levels GO:0010817 40 0.019
regulation of synaptic transmission GO:0050804 69 0.019
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
male courtship behavior veined wing vibration GO:0016545 21 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
vitamin metabolic process GO:0006766 2 0.019
calcium ion transport GO:0006816 24 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
positive regulation of developmental growth GO:0048639 62 0.018
salivary gland morphogenesis GO:0007435 145 0.018
nucleoside phosphate biosynthetic process GO:1901293 34 0.018
cellular response to growth factor stimulus GO:0071363 30 0.018
organic acid metabolic process GO:0006082 103 0.018
dorsal ventral axis specification GO:0009950 66 0.017
nucleotide metabolic process GO:0009117 161 0.017
response to other organism GO:0051707 293 0.017
response to insulin GO:0032868 29 0.017
response to lipopolysaccharide GO:0032496 4 0.017
camera type eye morphogenesis GO:0048593 2 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
heterocycle catabolic process GO:0046700 166 0.017
light induced release of internally sequestered calcium ion GO:0008377 1 0.017
compound eye retinal cell programmed cell death GO:0046667 23 0.017
negative regulation of signal transduction GO:0009968 206 0.016
organophosphate catabolic process GO:0046434 112 0.016
regulation of response to stress GO:0080134 200 0.016
double strand break repair GO:0006302 26 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
homeostatic process GO:0042592 199 0.016
hormone metabolic process GO:0042445 33 0.016
cell recognition GO:0008037 102 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
purine containing compound metabolic process GO:0072521 155 0.015
circadian behavior GO:0048512 76 0.015
Fly
meiotic chromosome segregation GO:0045132 59 0.015
detection of stimulus involved in sensory perception GO:0050906 92 0.015
lipid biosynthetic process GO:0008610 46 0.015
cellular amine metabolic process GO:0044106 12 0.015
positive regulation of immune response GO:0050778 63 0.015
regulation of immune system process GO:0002682 176 0.015
regulation of behavior GO:0050795 75 0.015
Fly
carbohydrate derivative catabolic process GO:1901136 118 0.014
response to endogenous stimulus GO:0009719 119 0.014
small molecule biosynthetic process GO:0044283 37 0.014
larval development GO:0002164 104 0.014
retina development in camera type eye GO:0060041 4 0.014
connective tissue development GO:0061448 3 0.014
regulation of insulin receptor signaling pathway GO:0046626 17 0.014
cell adhesion GO:0007155 136 0.014
reproductive behavior GO:0019098 122 0.014
anatomical structure homeostasis GO:0060249 97 0.014
cellular aldehyde metabolic process GO:0006081 10 0.014
regulation of cell development GO:0060284 215 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of phosphatase activity GO:0010921 3 0.014
anion transport GO:0006820 41 0.014
cellular response to decreased oxygen levels GO:0036294 30 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
regulation of hydrolase activity GO:0051336 97 0.013
regulation of protein metabolic process GO:0051246 256 0.013
regulation of membrane potential GO:0042391 35 0.013
response to alcohol GO:0097305 95 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
organelle assembly GO:0070925 198 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
rho protein signal transduction GO:0007266 14 0.013
intrinsic apoptotic signaling pathway GO:0097193 16 0.012
negative regulation of cell death GO:0060548 81 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
nucleotide catabolic process GO:0009166 109 0.012
insulin receptor signaling pathway GO:0008286 25 0.012
regulation of catalytic activity GO:0050790 185 0.012
cellular response to radiation GO:0071478 52 0.012
protein complex biogenesis GO:0070271 201 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.012
regulation of cell cycle GO:0051726 291 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
rhodopsin mediated signaling pathway GO:0016056 21 0.012
insecticide catabolic process GO:0046701 1 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of phosphorylation GO:0042325 147 0.012
male courtship behavior veined wing generated song production GO:0045433 20 0.012
eye photoreceptor cell development GO:0042462 81 0.011
meiotic cell cycle process GO:1903046 132 0.011
multicellular organismal aging GO:0010259 140 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
immune system development GO:0002520 57 0.011
regulation of cellular response to stress GO:0080135 89 0.011
nucleoside catabolic process GO:0009164 112 0.011
phagocytosis GO:0006909 215 0.011
forebrain development GO:0030900 2 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
maintenance of location GO:0051235 73 0.011
organic hydroxy compound biosynthetic process GO:1901617 21 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
oocyte maturation GO:0001556 3 0.011
secretion by cell GO:0032940 101 0.011
cell migration GO:0016477 238 0.010
regulation of system process GO:0044057 36 0.010
Fly
purine nucleotide catabolic process GO:0006195 109 0.010
response to organonitrogen compound GO:0010243 75 0.010
adaptation of rhodopsin mediated signaling GO:0016062 3 0.010
response to ethanol GO:0045471 59 0.010
response to inorganic substance GO:0010035 44 0.010
digestive tract morphogenesis GO:0048546 127 0.010
positive regulation of response to biotic stimulus GO:0002833 31 0.010

ort disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.063
disease of anatomical entity DOID:7 0 0.063
vascular disease DOID:178 0 0.063
cardiovascular system disease DOID:1287 0 0.063
hypertension DOID:10763 0 0.013