Drosophila melanogaster

23 known processes

KLHL18 (Dmel_CG3571)

CG3571 gene product from transcript CG3571-RA

(Aliases: CG3571,dKLHL18,anon-WO0118547.179,Dmel\CG3571)

KLHL18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 206 0.330
cell cell signaling involved in cell fate commitment GO:0045168 210 0.175
regionalization GO:0003002 416 0.148
rna splicing GO:0008380 83 0.095
positive regulation of cellular biosynthetic process GO:0031328 316 0.089
positive regulation of biosynthetic process GO:0009891 316 0.080
mrna processing GO:0006397 104 0.079
regulation of cellular ketone metabolic process GO:0010565 3 0.078
imaginal disc derived wing morphogenesis GO:0007476 337 0.071
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.070
dorsal ventral pattern formation GO:0009953 133 0.068
negative regulation of gene expression GO:0010629 387 0.068
chromatin organization GO:0006325 207 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.062
negative regulation of biosynthetic process GO:0009890 277 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.060
positive regulation of rna metabolic process GO:0051254 271 0.059
negative regulation of cellular metabolic process GO:0031324 382 0.059
mrna splicing via spliceosome GO:0000398 73 0.058
regulation of rna splicing GO:0043484 69 0.057
appendage development GO:0048736 401 0.057
macromolecular complex assembly GO:0065003 256 0.055
mrna metabolic process GO:0016071 124 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.053
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.053
response to abiotic stimulus GO:0009628 341 0.051
neurological system process GO:0050877 358 0.051
cytoplasmic transport GO:0016482 130 0.050
endocytosis GO:0006897 310 0.049
Fly
single organism behavior GO:0044708 391 0.049
negative regulation of cell communication GO:0010648 223 0.048
regulation of cellular amine metabolic process GO:0033238 3 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.044
negative regulation of signaling GO:0023057 219 0.044
positive regulation of signaling GO:0023056 243 0.044
positive regulation of signal transduction GO:0009967 223 0.043
small molecule metabolic process GO:0044281 305 0.043
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.043
organic acid metabolic process GO:0006082 103 0.043
positive regulation of transcription dna templated GO:0045893 266 0.042
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
rna processing GO:0006396 147 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
negative regulation of signal transduction GO:0009968 206 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.039
cognition GO:0050890 141 0.039
regulation of mrna metabolic process GO:1903311 72 0.037
negative regulation of nucleic acid templated transcription GO:1903507 240 0.037
positive regulation of rna biosynthetic process GO:1902680 266 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
Fly
segmentation GO:0035282 207 0.037
organic substance transport GO:0071702 257 0.036
macromolecule catabolic process GO:0009057 161 0.036
programmed cell death GO:0012501 257 0.036
Fly
death GO:0016265 284 0.036
Fly
regulation of cell division GO:0051302 72 0.035
cellular protein modification process GO:0006464 438 0.034
Fly
amine metabolic process GO:0009308 12 0.034
response to organic substance GO:0010033 284 0.034
immune response GO:0006955 246 0.033
response to external biotic stimulus GO:0043207 293 0.033
carboxylic acid metabolic process GO:0019752 92 0.033
appendage morphogenesis GO:0035107 397 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
immune system process GO:0002376 347 0.033
negative regulation of rna metabolic process GO:0051253 251 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
regulation of immune system process GO:0002682 176 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
embryonic pattern specification GO:0009880 174 0.031
rna splicing via transesterification reactions GO:0000375 73 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
cellular amino acid metabolic process GO:0006520 61 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
cell motility GO:0048870 251 0.030
Fly
regulation of organelle organization GO:0033043 196 0.030
developmental maturation GO:0021700 172 0.030
organic substance catabolic process GO:1901575 308 0.029
cell maturation GO:0048469 144 0.028
protein localization GO:0008104 284 0.028
wing disc morphogenesis GO:0007472 344 0.028
exocrine system development GO:0035272 162 0.027
response to temperature stimulus GO:0009266 106 0.027
protein modification process GO:0036211 438 0.027
Fly
cellular catabolic process GO:0044248 372 0.027
chromosome organization GO:0051276 360 0.026
Fly
regulation of mrna processing GO:0050684 71 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
camera type eye development GO:0043010 4 0.026
axis specification GO:0009798 167 0.026
positive regulation of cell communication GO:0010647 250 0.026
phagocytosis GO:0006909 215 0.026
Fly
regulation of mrna splicing via spliceosome GO:0048024 64 0.025
cellular ketone metabolic process GO:0042180 24 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.025
localization of cell GO:0051674 257 0.025
Fly
regulation of multicellular organismal development GO:2000026 414 0.025
muscle structure development GO:0061061 224 0.025
vesicle mediated transport GO:0016192 381 0.024
Fly
cellular amine metabolic process GO:0044106 12 0.024
cell division GO:0051301 248 0.024
single organism cellular localization GO:1902580 180 0.024
protein acetylation GO:0006473 39 0.024
blastoderm segmentation GO:0007350 159 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
response to biotic stimulus GO:0009607 294 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
negative regulation of response to stimulus GO:0048585 258 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
Fly
epithelial cell differentiation GO:0030855 322 0.022
Fly
single organism catabolic process GO:0044712 228 0.022
stem cell development GO:0048864 79 0.022
protein acylation GO:0043543 42 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
organelle fission GO:0048285 340 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
response to heat GO:0009408 63 0.021
aromatic compound catabolic process GO:0019439 166 0.021
catabolic process GO:0009056 409 0.020
defense response to other organism GO:0098542 225 0.020
anterior posterior axis specification GO:0009948 109 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
multicellular organismal aging GO:0010259 140 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
tube morphogenesis GO:0035239 191 0.019
mrna cis splicing via spliceosome GO:0045292 1 0.019
tripartite regional subdivision GO:0007351 103 0.019
salivary gland development GO:0007431 162 0.019
regulation of proteolysis GO:0030162 87 0.019
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
regulation of multi organism process GO:0043900 131 0.019
cytokinesis GO:0000910 90 0.019
rna localization GO:0006403 115 0.019
secondary metabolic process GO:0019748 75 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
imaginal disc pattern formation GO:0007447 91 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
ovarian follicle cell development GO:0030707 248 0.018
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
synaptic transmission GO:0007268 288 0.018
Fly
regulation of cell cycle GO:0051726 291 0.018
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.017
Fly
regulation of meiosis GO:0040020 3 0.017
intracellular transport GO:0046907 228 0.017
cellular macromolecule localization GO:0070727 220 0.017
defense response to bacterium GO:0042742 178 0.017
cell proliferation GO:0008283 299 0.017
regulation of localization GO:0032879 275 0.017
response to other organism GO:0051707 293 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
regulation of molecular function GO:0065009 217 0.016
Fly
defense response GO:0006952 300 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
wing disc pattern formation GO:0035222 66 0.016
cellular response to organic substance GO:0071310 132 0.016
regulation of protein metabolic process GO:0051246 256 0.016
Fly
regulation of catabolic process GO:0009894 170 0.016
humoral immune response GO:0006959 117 0.016
cell death GO:0008219 279 0.016
Fly
gland morphogenesis GO:0022612 145 0.016
cellular protein catabolic process GO:0044257 83 0.015
learning or memory GO:0007611 141 0.015
regulation of mapk cascade GO:0043408 92 0.015
chromosome separation GO:0051304 42 0.015
response to radiation GO:0009314 155 0.015
chromatin remodeling GO:0006338 72 0.015
mitotic nuclear division GO:0007067 213 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
homeostatic process GO:0042592 199 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
mrna catabolic process GO:0006402 33 0.014
tissue death GO:0016271 102 0.014
single organism biosynthetic process GO:0044711 206 0.014
stem cell differentiation GO:0048863 117 0.014
endodermal cell differentiation GO:0035987 3 0.014
wnt signaling pathway GO:0016055 98 0.014
positive regulation of immune response GO:0050778 63 0.014
embryonic axis specification GO:0000578 107 0.014
regulation of cell cycle process GO:0010564 181 0.014
regulation of protein catabolic process GO:0042176 55 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
larval development GO:0002164 104 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
connective tissue development GO:0061448 3 0.014
response to bacterium GO:0009617 198 0.014
regulation of cell differentiation GO:0045595 302 0.014
regulation of nuclear division GO:0051783 58 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
regulation of chromosome organization GO:0033044 64 0.014
cell projection assembly GO:0030031 94 0.014
regulation of translation GO:0006417 56 0.013
molting cycle GO:0042303 56 0.013
protein targeting GO:0006605 64 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of response to external stimulus GO:0032101 115 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
sensory organ morphogenesis GO:0090596 260 0.013
regulation of mitosis GO:0007088 56 0.013
internal peptidyl lysine acetylation GO:0018393 38 0.013
body morphogenesis GO:0010171 2 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
salivary gland morphogenesis GO:0007435 145 0.013
retina development in camera type eye GO:0060041 4 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
chromatin modification GO:0016568 147 0.013
regulation of cell proliferation GO:0042127 163 0.013
antimicrobial humoral response GO:0019730 99 0.012
chromosome segregation GO:0007059 157 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of cellular localization GO:0060341 136 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
regulation of cell development GO:0060284 215 0.012
dephosphorylation GO:0016311 51 0.012
regulation of chromatin organization GO:1902275 32 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
regulation of immune response GO:0050776 118 0.012
apoptotic process GO:0006915 159 0.012
Fly
spermatogenesis GO:0007283 200 0.012
Fly
determination of adult lifespan GO:0008340 137 0.012
establishment of protein localization GO:0045184 163 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
pigment metabolic process GO:0042440 84 0.012
establishment of rna localization GO:0051236 47 0.012
response to endogenous stimulus GO:0009719 119 0.012
negative regulation of immune system process GO:0002683 50 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
ameboidal type cell migration GO:0001667 151 0.012
Fly
single organism intracellular transport GO:1902582 207 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.011
response to wounding GO:0009611 94 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
cell cycle arrest GO:0007050 4 0.011
rna transport GO:0050658 46 0.011
regulation of response to stress GO:0080134 200 0.011
establishment of localization in cell GO:0051649 402 0.011
forebrain development GO:0030900 2 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
protein catabolic process GO:0030163 101 0.011
anatomical structure homeostasis GO:0060249 97 0.011
regulation of intracellular transport GO:0032386 64 0.011
nucleobase containing compound transport GO:0015931 56 0.011
taxis GO:0042330 304 0.011
mapk cascade GO:0000165 107 0.011
internal protein amino acid acetylation GO:0006475 38 0.011
telencephalon development GO:0021537 2 0.011
chemotaxis GO:0006935 249 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
oxoacid metabolic process GO:0043436 103 0.011
histolysis GO:0007559 102 0.011
negative regulation of developmental process GO:0051093 201 0.011
tube development GO:0035295 244 0.011
organic cyclic compound catabolic process GO:1901361 168 0.010
nuclear transport GO:0051169 72 0.010
intracellular signal transduction GO:0035556 300 0.010
protein complex biogenesis GO:0070271 201 0.010
protein transport GO:0015031 155 0.010
spinal cord development GO:0021510 1 0.010
autophagic cell death GO:0048102 83 0.010
eye development GO:0001654 323 0.010
limb development GO:0060173 1 0.010
positive regulation of programmed cell death GO:0043068 62 0.010
Fly
epithelial cell development GO:0002064 274 0.010
Fly
positive regulation of protein metabolic process GO:0051247 128 0.010
Fly
dna templated transcription elongation GO:0006354 18 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
intracellular protein transport GO:0006886 104 0.010
sulfur compound metabolic process GO:0006790 59 0.010

KLHL18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
disease of cellular proliferation DOID:14566 0 0.015