Drosophila melanogaster

174 known processes

kto (Dmel_CG8491)

kohtalo

(Aliases: dTrap230,Srb8/KTO/TRAP230,siren1,Trap230,Dmel\CG8491,CG8491,med12/kto,dTRAP230,Med12,MED12,Kto,SRB8,Kto/Med12)

kto biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.940
imaginal disc derived appendage morphogenesis GO:0035114 395 0.901
positive regulation of biosynthetic process GO:0009891 316 0.886
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.836
Mouse
sex comb development GO:0045498 8 0.774
leg disc development GO:0035218 92 0.773
imaginal disc derived leg morphogenesis GO:0007480 80 0.693
positive regulation of rna metabolic process GO:0051254 271 0.623
Mouse
leg disc morphogenesis GO:0007478 80 0.621
regulation of multicellular organismal development GO:2000026 414 0.617
positive regulation of cellular biosynthetic process GO:0031328 316 0.597
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.592
Mouse
cell cycle phase transition GO:0044770 140 0.585
negative regulation of cellular biosynthetic process GO:0031327 277 0.575
neuroblast proliferation GO:0007405 74 0.548
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.541
mitotic cell cycle phase transition GO:0044772 138 0.485
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.475
negative regulation of nucleic acid templated transcription GO:1903507 240 0.448
immune system process GO:0002376 347 0.433
programmed cell death GO:0012501 257 0.419
negative regulation of rna biosynthetic process GO:1902679 240 0.419
appendage development GO:0048736 401 0.411
post embryonic appendage morphogenesis GO:0035120 385 0.407
transcription from rna polymerase ii promoter GO:0006366 368 0.397
appendage morphogenesis GO:0035107 397 0.396
catabolic process GO:0009056 409 0.389
regulation of nervous system development GO:0051960 248 0.389
regulation of cell cycle process GO:0010564 181 0.379
cellular protein modification process GO:0006464 438 0.365
response to alcohol GO:0097305 95 0.347
negative regulation of transcription dna templated GO:0045892 237 0.345
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.334
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.327
mitotic g2 dna damage checkpoint GO:0007095 69 0.319
imaginal disc derived leg segmentation GO:0036011 26 0.314
regulation of cell cycle phase transition GO:1901987 130 0.311
developmental programmed cell death GO:0010623 138 0.305
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.303
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.297
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.291
cell proliferation GO:0008283 299 0.288
positive regulation of nucleic acid templated transcription GO:1903508 266 0.285
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.275
Mouse
regulation of neurogenesis GO:0050767 158 0.275
body morphogenesis GO:0010171 2 0.268
neural precursor cell proliferation GO:0061351 75 0.262
mitotic dna integrity checkpoint GO:0044774 75 0.253
regulation of stem cell proliferation GO:0072091 40 0.246
nucleobase containing compound catabolic process GO:0034655 165 0.243
stem cell proliferation GO:0072089 88 0.243
cellular catabolic process GO:0044248 372 0.236
negative regulation of stem cell proliferation GO:2000647 30 0.234
negative regulation of gene expression GO:0010629 387 0.215
negative regulation of neural precursor cell proliferation GO:2000178 27 0.214
cellular macromolecule catabolic process GO:0044265 136 0.212
negative regulation of cell cycle phase transition GO:1901988 103 0.210
regulation of mitotic cell cycle phase transition GO:1901990 130 0.205
negative regulation of developmental process GO:0051093 201 0.204
nuclear division GO:0000280 332 0.204
negative regulation of cell differentiation GO:0045596 143 0.203
tissue death GO:0016271 102 0.197
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.191
mitotic dna damage checkpoint GO:0044773 74 0.188
mitotic nuclear division GO:0007067 213 0.186
aromatic compound catabolic process GO:0019439 166 0.183
organic substance catabolic process GO:1901575 308 0.178
regulation of cell development GO:0060284 215 0.176
retina development in camera type eye GO:0060041 4 0.170
imaginal disc derived wing morphogenesis GO:0007476 337 0.167
regionalization GO:0003002 416 0.167
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.164
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.163
positive regulation of rna biosynthetic process GO:1902680 266 0.161
Mouse
camera type eye development GO:0043010 4 0.158
negative regulation of rna metabolic process GO:0051253 251 0.152
imaginal disc pattern formation GO:0007447 91 0.151
larval midgut histolysis GO:0035069 22 0.150
molting cycle GO:0042303 56 0.149
snrna processing GO:0016180 14 0.148
negative regulation of neuroblast proliferation GO:0007406 27 0.147
dendrite development GO:0016358 204 0.144
wing disc pattern formation GO:0035222 66 0.142
positive regulation of programmed cell death GO:0043068 62 0.140
anterior posterior pattern specification GO:0009952 136 0.138
Mouse
negative regulation of mitotic cell cycle GO:0045930 109 0.133
protein modification by small protein conjugation or removal GO:0070647 106 0.133
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.132
negative regulation of biosynthetic process GO:0009890 277 0.123
negative regulation of cell cycle process GO:0010948 109 0.116
kidney epithelium development GO:0072073 3 0.115
g2 dna damage checkpoint GO:0031572 69 0.110
protein ubiquitination GO:0016567 70 0.109
regulation of cellular component biogenesis GO:0044087 201 0.109
cellular response to dna damage stimulus GO:0006974 223 0.107
regulation of apoptotic process GO:0042981 130 0.107
blastoderm segmentation GO:0007350 159 0.105
regulation of neuroblast proliferation GO:1902692 34 0.105
appendage segmentation GO:0035285 26 0.103
negative regulation of cell proliferation GO:0008285 69 0.102
macromolecule catabolic process GO:0009057 161 0.102
organelle fission GO:0048285 340 0.101
morphogenesis of an epithelium GO:0002009 276 0.099
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.098
protein modification process GO:0036211 438 0.097
intracellular signal transduction GO:0035556 300 0.096
regulation of cell proliferation GO:0042127 163 0.096
positive regulation of gene expression GO:0010628 290 0.089
Mouse
response to oxygen containing compound GO:1901700 200 0.089
exocrine system development GO:0035272 162 0.088
positive regulation of cell death GO:0010942 69 0.086
hematopoietic or lymphoid organ development GO:0048534 57 0.084
sensory organ morphogenesis GO:0090596 260 0.081
rna catabolic process GO:0006401 37 0.081
cellular nitrogen compound catabolic process GO:0044270 165 0.080
regulation of molecular function GO:0065009 217 0.080
regulation of cell differentiation GO:0045595 302 0.080
death GO:0016265 284 0.079
growth GO:0040007 359 0.077
Mouse
apoptotic process GO:0006915 159 0.077
heterocycle catabolic process GO:0046700 166 0.076
imaginal disc derived appendage development GO:0048737 399 0.075
segmentation GO:0035282 207 0.073
positive regulation of signal transduction GO:0009967 223 0.073
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.073
regulation of cell cycle GO:0051726 291 0.073
endocytosis GO:0006897 310 0.072
dna metabolic process GO:0006259 227 0.072
positive regulation of catalytic activity GO:0043085 118 0.072
chaeta development GO:0022416 97 0.071
cell death GO:0008219 279 0.070
small molecule metabolic process GO:0044281 305 0.070
negative regulation of multicellular organismal process GO:0051241 142 0.070
snrna metabolic process GO:0016073 14 0.068
compound eye development GO:0048749 307 0.068
positive regulation of macromolecule metabolic process GO:0010604 405 0.067
Mouse
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.067
regulation of intracellular signal transduction GO:1902531 236 0.065
salivary gland morphogenesis GO:0007435 145 0.064
regulation of cell death GO:0010941 173 0.063
dendrite morphogenesis GO:0048813 199 0.063
mitotic cell cycle checkpoint GO:0007093 88 0.062
regulation of immune system process GO:0002682 176 0.062
histolysis GO:0007559 102 0.061
cell cycle checkpoint GO:0000075 95 0.061
positive regulation of cellular component organization GO:0051130 156 0.061
regulation of mitotic cell cycle GO:0007346 190 0.059
oxoacid metabolic process GO:0043436 103 0.059
response to radiation GO:0009314 155 0.059
dna integrity checkpoint GO:0031570 81 0.058
proteolysis GO:0006508 192 0.057
meiotic cell cycle GO:0051321 171 0.057
positive regulation of response to stimulus GO:0048584 323 0.057
regulation of neuron death GO:1901214 26 0.056
salivary gland cell autophagic cell death GO:0035071 83 0.056
organonitrogen compound metabolic process GO:1901564 318 0.056
kidney development GO:0001822 3 0.056
response to sterol GO:0036314 34 0.054
camera type eye morphogenesis GO:0048593 2 0.054
regulation of nuclear division GO:0051783 58 0.053
organic acid metabolic process GO:0006082 103 0.053
apoptotic signaling pathway GO:0097190 27 0.052
gonad development GO:0008406 50 0.051
response to organic substance GO:0010033 284 0.051
protein phosphorylation GO:0006468 169 0.051
regulation of multi organism process GO:0043900 131 0.051
neurological system process GO:0050877 358 0.050
wing disc morphogenesis GO:0007472 344 0.050
chromosome organization GO:0051276 360 0.049
negative regulation of cell cycle GO:0045786 116 0.048
regulation of chromosome organization GO:0033044 64 0.048
induction of programmed cell death by ecdysone GO:0035078 12 0.047
regulation of cellular catabolic process GO:0031329 157 0.047
embryonic pattern specification GO:0009880 174 0.046
regulation of programmed cell death GO:0043067 152 0.046
negative regulation of neurogenesis GO:0050768 53 0.044
mitotic g2 m transition checkpoint GO:0044818 70 0.044
positive regulation of molecular function GO:0044093 136 0.044
regulation of catalytic activity GO:0050790 185 0.044
tripartite regional subdivision GO:0007351 103 0.044
response to biotic stimulus GO:0009607 294 0.043
single organism catabolic process GO:0044712 228 0.043
regulation of neuron differentiation GO:0045664 103 0.043
phosphorylation GO:0016310 294 0.043
embryonic axis specification GO:0000578 107 0.042
chromatin modification GO:0016568 147 0.042
negative regulation of apoptotic process GO:0043066 63 0.042
response to extracellular stimulus GO:0009991 116 0.042
respiratory system development GO:0060541 213 0.042
negative regulation of cell death GO:0060548 81 0.041
chromatin remodeling GO:0006338 72 0.041
histone modification GO:0016570 106 0.040
negative regulation of programmed cell death GO:0043069 72 0.040
g1 s transition of mitotic cell cycle GO:0000082 31 0.040
ras protein signal transduction GO:0007265 88 0.039
response to nutrient levels GO:0031667 114 0.038
dna damage checkpoint GO:0000077 78 0.038
response to ecdysone GO:0035075 34 0.037
regulation of reproductive process GO:2000241 54 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.036
taxis GO:0042330 304 0.036
response to light stimulus GO:0009416 124 0.035
positive regulation of protein metabolic process GO:0051247 128 0.035
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
covalent chromatin modification GO:0016569 106 0.034
cellular response to radiation GO:0071478 52 0.034
dna templated transcription initiation GO:0006352 25 0.034
atp dependent chromatin remodeling GO:0043044 22 0.034
negative regulation of nervous system development GO:0051961 92 0.034
wing disc dorsal ventral pattern formation GO:0048190 47 0.033
autophagic cell death GO:0048102 83 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
Mouse
eye antennal disc development GO:0035214 60 0.032
regulation of gene expression epigenetic GO:0040029 128 0.032
cell division GO:0051301 248 0.032
autophagy GO:0006914 108 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
positive regulation of signaling GO:0023056 243 0.031
negative regulation of neuron death GO:1901215 18 0.031
muscle structure development GO:0061061 224 0.031
snrna 3 end processing GO:0034472 14 0.031
developmental pigmentation GO:0048066 68 0.030
regulation of ras protein signal transduction GO:0046578 93 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
developmental maturation GO:0021700 172 0.029
molting cycle chitin based cuticle GO:0007591 56 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
ncrna metabolic process GO:0034660 43 0.028
regulation of phosphorylation GO:0042325 147 0.028
lipid metabolic process GO:0006629 121 0.028
dna repair GO:0006281 54 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.027
axon development GO:0061564 297 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
tissue morphogenesis GO:0048729 297 0.027
Mouse
response to external biotic stimulus GO:0043207 293 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
eye development GO:0001654 323 0.027
reproductive behavior GO:0019098 122 0.026
peptidyl lysine modification GO:0018205 57 0.026
phagocytosis GO:0006909 215 0.026
regulation of synapse organization GO:0050807 110 0.026
neuron projection guidance GO:0097485 241 0.026
protein complex assembly GO:0006461 200 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.026
regulation of mitosis GO:0007088 56 0.026
organophosphate metabolic process GO:0019637 195 0.025
chromosome segregation GO:0007059 157 0.025
gland morphogenesis GO:0022612 145 0.025
development of primary sexual characteristics GO:0045137 50 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
negative regulation of cell development GO:0010721 62 0.025
regulation of nucleotide metabolic process GO:0006140 62 0.025
intrinsic apoptotic signaling pathway GO:0097193 16 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
larval development GO:0002164 104 0.024
ribose phosphate metabolic process GO:0019693 145 0.024
multi multicellular organism process GO:0044706 123 0.024
ncrna 3 end processing GO:0043628 17 0.024
cellular response to organic substance GO:0071310 132 0.024
response to ketone GO:1901654 34 0.024
mrna catabolic process GO:0006402 33 0.024
tube development GO:0035295 244 0.023
Mouse
regulation of system process GO:0044057 36 0.023
epithelial tube morphogenesis GO:0060562 88 0.023
Mouse
peptidyl amino acid modification GO:0018193 105 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.023
regulation of neural precursor cell proliferation GO:2000177 35 0.023
regulation of chromosome segregation GO:0051983 32 0.022
axonogenesis GO:0007409 290 0.022
response to oxidative stress GO:0006979 86 0.022
muscle cell differentiation GO:0042692 103 0.022
vesicle localization GO:0051648 55 0.022
specification of organ identity GO:0010092 3 0.022
amine metabolic process GO:0009308 12 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
reproductive structure development GO:0048608 74 0.022
triglyceride biosynthetic process GO:0019432 2 0.022
apoptotic process involved in morphogenesis GO:0060561 3 0.022
gene silencing by rna GO:0031047 57 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
induction of programmed cell death GO:0012502 12 0.021
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
pigmentation GO:0043473 75 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
cellular response to extracellular stimulus GO:0031668 64 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
Mouse
malpighian tubule development GO:0072002 64 0.020
cellular protein catabolic process GO:0044257 83 0.020
brain development GO:0007420 120 0.020
regulation of purine nucleotide metabolic process GO:1900542 62 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
cellular amine metabolic process GO:0044106 12 0.020
regulation of embryonic development GO:0045995 68 0.019
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.019
nucleotide metabolic process GO:0009117 161 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.018
phosphorylation of rna polymerase ii c terminal domain GO:0070816 1 0.018
axon guidance GO:0007411 233 0.018
regulation of hydrolase activity GO:0051336 97 0.018
positive regulation of wnt signaling pathway GO:0030177 25 0.018
posttranscriptional gene silencing GO:0016441 46 0.018
negative regulation of signal transduction GO:0009968 206 0.018
connective tissue development GO:0061448 3 0.018
pigment metabolic process GO:0042440 84 0.018
heart development GO:0007507 82 0.018
Mouse
molting cycle process GO:0022404 29 0.018
embryonic hemopoiesis GO:0035162 26 0.018
positive regulation of multi organism process GO:0043902 40 0.018
chromatin organization GO:0006325 207 0.018
purine nucleoside catabolic process GO:0006152 112 0.017
cellular ketone metabolic process GO:0042180 24 0.017
forebrain development GO:0030900 2 0.017
regulation of chromatin organization GO:1902275 32 0.017
regulation of organelle organization GO:0033043 196 0.017
regulation of proteolysis GO:0030162 87 0.017
regulation of growth GO:0040008 233 0.017
head development GO:0060322 135 0.017
induction of programmed cell death by hormones GO:0035081 12 0.017
internal protein amino acid acetylation GO:0006475 38 0.017
salivary gland development GO:0007431 162 0.017
regulation of protein modification process GO:0031399 112 0.017
gland development GO:0048732 191 0.017
neuron apoptotic process GO:0051402 17 0.017
mrna splicing via spliceosome GO:0000398 73 0.017
salivary gland histolysis GO:0035070 88 0.017
immune system development GO:0002520 57 0.017
cell type specific apoptotic process GO:0097285 38 0.017
kidney morphogenesis GO:0060993 3 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
mapk cascade GO:0000165 107 0.017
sex differentiation GO:0007548 81 0.016
response to lipid GO:0033993 38 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of protein metabolic process GO:0051246 256 0.016
retina morphogenesis in camera type eye GO:0060042 2 0.016
sensory perception GO:0007600 196 0.016
mitotic sister chromatid segregation GO:0000070 87 0.016
regulation of vesicle mediated transport GO:0060627 59 0.016
regulation of cell projection organization GO:0031344 92 0.016
morphogenesis of follicular epithelium GO:0016333 36 0.016
neuron death GO:0070997 27 0.016
gtp catabolic process GO:0006184 72 0.016
cellular response to external stimulus GO:0071496 66 0.015
zymogen activation GO:0031638 20 0.015
cellular component disassembly GO:0022411 46 0.015
negative regulation of chromosome segregation GO:0051985 14 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
epithelial cell differentiation GO:0030855 322 0.015
response to virus GO:0009615 28 0.015
protein catabolic process GO:0030163 101 0.015
hemopoiesis GO:0030097 46 0.015
regulation of endopeptidase activity GO:0052548 36 0.015
defense response to other organism GO:0098542 225 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
organ growth GO:0035265 56 0.015
nephron epithelium development GO:0072009 3 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
macromolecular complex assembly GO:0065003 256 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
negative regulation of cell communication GO:0010648 223 0.015
imaginal disc derived wing vein specification GO:0007474 48 0.015
reproductive system development GO:0061458 74 0.015
purine containing compound metabolic process GO:0072521 155 0.014
branching morphogenesis of an epithelial tube GO:0048754 45 0.014
anatomical structure homeostasis GO:0060249 97 0.014
negative regulation of neuron apoptotic process GO:0043524 14 0.014
eye photoreceptor cell fate commitment GO:0042706 37 0.014
histone exchange GO:0043486 21 0.014
phosphatidylinositol mediated signaling GO:0048015 4 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
positive regulation of protein modification process GO:0031401 58 0.014
renal system development GO:0072001 72 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
cellular amide metabolic process GO:0043603 80 0.014
oocyte differentiation GO:0009994 145 0.014
protein dna complex subunit organization GO:0071824 86 0.014
rna processing GO:0006396 147 0.013
response to other organism GO:0051707 293 0.013
regulation of developmental growth GO:0048638 174 0.013
protein targeting to nucleus GO:0044744 51 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of cell growth GO:0001558 43 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
sister chromatid segregation GO:0000819 92 0.013
open tracheal system development GO:0007424 204 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
protein maturation GO:0051604 71 0.013
somatic stem cell division GO:0048103 37 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
regulation of embryonic pattern specification GO:1902875 27 0.013
modification dependent protein catabolic process GO:0019941 78 0.012
gene silencing GO:0016458 138 0.012
cellular lipid metabolic process GO:0044255 83 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.012
sensory perception of mechanical stimulus GO:0050954 72 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
equator specification GO:0045317 4 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of defense response to bacterium GO:1900424 30 0.012
response to uv GO:0009411 24 0.012
intracellular receptor signaling pathway GO:0030522 19 0.012
regulation of sister chromatid cohesion GO:0007063 2 0.012
regulation of mitotic sister chromatid separation GO:0010965 28 0.012
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.012
chromatin silencing GO:0006342 76 0.012
regulation of nurse cell apoptotic process GO:0045477 9 0.012
nuclear transcribed mrna catabolic process GO:0000956 24 0.012
macromolecule deacylation GO:0098732 11 0.012
regulation of neuron apoptotic process GO:0043523 16 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
regulation of gtpase activity GO:0043087 44 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
jak stat cascade GO:0007259 49 0.011
peptidyl threonine modification GO:0018210 3 0.011
positive regulation of developmental process GO:0051094 143 0.011
optic placode formation GO:0001743 4 0.011
maintenance of location in cell GO:0051651 28 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
positive regulation of organ growth GO:0046622 12 0.011
regulation of localization GO:0032879 275 0.011
establishment of localization in cell GO:0051649 402 0.011
response to abiotic stimulus GO:0009628 341 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
erk1 and erk2 cascade GO:0070371 39 0.011
response to heat GO:0009408 63 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
regulation of humoral immune response GO:0002920 51 0.010
positive regulation of cell communication GO:0010647 250 0.010
protein localization GO:0008104 284 0.010
spermatogenesis GO:0007283 200 0.010
regulation of nucleoside metabolic process GO:0009118 50 0.010
embryonic morphogenesis GO:0048598 206 0.010
Mouse
positive regulation of cellular component biogenesis GO:0044089 80 0.010
cellular response to uv GO:0034644 12 0.010
positive regulation of transferase activity GO:0051347 26 0.010
macromolecular complex disassembly GO:0032984 37 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
metaphase anaphase transition of cell cycle GO:0044784 28 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010
memory GO:0007613 94 0.010
imaginal disc growth GO:0007446 37 0.010

kto disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.035
disease of anatomical entity DOID:7 0 0.032
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.028
nervous system disease DOID:863 0 0.018