Drosophila melanogaster

61 known processes

tral (Dmel_CG10686)

trailer hitch

(Aliases: Lsm15,CG10686,p70,p67,TRAL,LSm15,Scd6p,DmLSm15,BEST:GH08269,anon-WO02059370.24,anon-EST:Posey139,Tral,Dmel\CG10686,anon-WO0172774.89)

tral biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte axis specification GO:0007309 108 0.996
oocyte construction GO:0007308 112 0.995
oocyte development GO:0048599 124 0.994
oocyte differentiation GO:0009994 145 0.985
anterior posterior axis specification embryo GO:0008595 103 0.959
rna localization GO:0006403 115 0.952
embryonic pattern specification GO:0009880 174 0.945
oocyte anterior posterior axis specification GO:0007314 72 0.938
blastoderm segmentation GO:0007350 159 0.932
embryonic axis specification GO:0000578 107 0.920
anterior posterior axis specification GO:0009948 109 0.910
tripartite regional subdivision GO:0007351 103 0.909
anterior posterior pattern specification GO:0009952 136 0.899
pole plasm oskar mrna localization GO:0045451 46 0.887
positive regulation of gene expression GO:0010628 290 0.853
positive regulation of nucleic acid templated transcription GO:1903508 266 0.818
transcription from rna polymerase ii promoter GO:0006366 368 0.809
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.808
regionalization GO:0003002 416 0.773
chorion containing eggshell formation GO:0007304 105 0.739
germarium derived egg chamber formation GO:0007293 101 0.722
segmentation GO:0035282 207 0.711
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.702
positive regulation of biosynthetic process GO:0009891 316 0.697
pole plasm rna localization GO:0007316 52 0.696
pole plasm mrna localization GO:0019094 49 0.609
macromolecule catabolic process GO:0009057 161 0.601
protein complex assembly GO:0006461 200 0.595
positive regulation of rna biosynthetic process GO:1902680 266 0.591
eggshell formation GO:0030703 105 0.578
positive regulation of transcription dna templated GO:0045893 266 0.572
rna catabolic process GO:0006401 37 0.569
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.547
pole plasm assembly GO:0007315 61 0.536
intracellular mrna localization GO:0008298 66 0.534
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.514
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.492
cellular macromolecule catabolic process GO:0044265 136 0.490
actin cytoskeleton organization GO:0030036 206 0.488
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.486
positive regulation of rna metabolic process GO:0051254 271 0.482
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.482
developmental maturation GO:0021700 172 0.479
positive regulation of cellular biosynthetic process GO:0031328 316 0.439
mitotic dna integrity checkpoint GO:0044774 75 0.428
ribonucleoprotein complex biogenesis GO:0022613 31 0.428
Human
death GO:0016265 284 0.417
Worm
axis specification GO:0009798 167 0.396
mrna metabolic process GO:0016071 124 0.393
protein modification by small protein conjugation or removal GO:0070647 106 0.390
translation GO:0006412 69 0.387
nucleobase containing compound catabolic process GO:0034655 165 0.385
cellular macromolecular complex assembly GO:0034622 153 0.379
Human
negative regulation of biosynthetic process GO:0009890 277 0.374
macromolecular complex assembly GO:0065003 256 0.373
Human
oocyte microtubule cytoskeleton organization GO:0016325 35 0.369
cellular catabolic process GO:0044248 372 0.330
positive regulation of mrna processing GO:0050685 4 0.313
nuclear pore organization GO:0006999 1 0.303
negative regulation of multicellular organismal process GO:0051241 142 0.302
nuclear transcribed mrna catabolic process GO:0000956 24 0.301
negative regulation of gene expression GO:0010629 387 0.278
organic substance catabolic process GO:1901575 308 0.273
positive regulation of mrna metabolic process GO:1903313 5 0.269
maternal determination of anterior posterior axis embryo GO:0008358 74 0.267
regulation of mrna processing GO:0050684 71 0.253
cytoplasm organization GO:0007028 64 0.253
cellular response to abiotic stimulus GO:0071214 58 0.248
gene silencing GO:0016458 138 0.245
intracellular transport GO:0046907 228 0.226
embryo development ending in birth or egg hatching GO:0009792 152 0.223
Worm
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.213
establishment of localization in cell GO:0051649 402 0.211
protein modification process GO:0036211 438 0.211
negative regulation of translation GO:0017148 28 0.205
dorsal appendage formation GO:0046843 47 0.201
protein modification by small protein conjugation GO:0032446 79 0.195
regulation of intracellular transport GO:0032386 64 0.194
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.192
eggshell chorion assembly GO:0007306 66 0.186
regulation of meiosis GO:0040020 3 0.182
rna processing GO:0006396 147 0.180
posttranscriptional regulation of gene expression GO:0010608 145 0.180
catabolic process GO:0009056 409 0.179
negative regulation of cellular metabolic process GO:0031324 382 0.177
regulation of translation GO:0006417 56 0.176
ribonucleoprotein complex assembly GO:0022618 23 0.159
Human
regulation of synapse assembly GO:0051963 94 0.154
protein localization to nucleus GO:0034504 55 0.152
heterocycle catabolic process GO:0046700 166 0.152
positive regulation of macromolecule metabolic process GO:0010604 405 0.152
regulation of transport GO:0051049 181 0.150
ribonucleoprotein complex subunit organization GO:0071826 28 0.149
Human
organic cyclic compound catabolic process GO:1901361 168 0.149
cell maturation GO:0048469 144 0.146
gene silencing by rna GO:0031047 57 0.145
dorsal ventral axis specification GO:0009950 66 0.140
mitotic cell cycle checkpoint GO:0007093 88 0.140
cellular macromolecule localization GO:0070727 220 0.140
aromatic compound catabolic process GO:0019439 166 0.137
negative regulation of cellular biosynthetic process GO:0031327 277 0.137
mrna catabolic process GO:0006402 33 0.137
regulation of mrna metabolic process GO:1903311 72 0.132
posttranscriptional gene silencing GO:0016441 46 0.130
organic substance transport GO:0071702 257 0.122
regulation of cytoplasmic transport GO:1903649 47 0.120
cellular component assembly involved in morphogenesis GO:0010927 151 0.120
ncrna metabolic process GO:0034660 43 0.115
epithelial cell development GO:0002064 274 0.114
regulation of pole plasm oskar mrna localization GO:0007317 27 0.110
posttranscriptional gene silencing by rna GO:0035194 45 0.107
mrna processing GO:0006397 104 0.106
cellular protein modification process GO:0006464 438 0.105
dna damage checkpoint GO:0000077 78 0.104
cellular protein complex assembly GO:0043623 71 0.103
cellular nitrogen compound catabolic process GO:0044270 165 0.103
regulation of response to stress GO:0080134 200 0.096
response to other organism GO:0051707 293 0.092
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.089
organelle assembly GO:0070925 198 0.088
Human
regulation of mrna splicing via spliceosome GO:0048024 64 0.086
protein ubiquitination GO:0016567 70 0.083
regulation of cellular localization GO:0060341 136 0.081
protein complex biogenesis GO:0070271 201 0.081
cellular response to chemical stimulus GO:0070887 199 0.081
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.080
centrosome duplication GO:0051298 121 0.078
single organism intracellular transport GO:1902582 207 0.077
protein targeting to nucleus GO:0044744 51 0.076
body morphogenesis GO:0010171 2 0.076
carboxylic acid metabolic process GO:0019752 92 0.072
single organism nuclear import GO:1902593 51 0.072
ovarian follicle cell development GO:0030707 248 0.071
regulation of nucleocytoplasmic transport GO:0046822 35 0.070
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.067
regulation of localization GO:0032879 275 0.066
spindle elongation GO:0051231 83 0.065
single organism cellular localization GO:1902580 180 0.065
modification dependent macromolecule catabolic process GO:0043632 79 0.065
actin filament organization GO:0007015 126 0.065
regulation of gene expression epigenetic GO:0040029 128 0.064
chromatin organization GO:0006325 207 0.064
taxis GO:0042330 304 0.062
cell division GO:0051301 248 0.062
Worm
response to biotic stimulus GO:0009607 294 0.062
regulation of protein metabolic process GO:0051246 256 0.061
muscle structure development GO:0061061 224 0.060
regulation of multicellular organismal development GO:2000026 414 0.058
positive regulation of protein import into nucleus GO:0042307 21 0.057
actin filament based process GO:0030029 220 0.056
multi organism behavior GO:0051705 175 0.056
oocyte dorsal ventral axis specification GO:0007310 34 0.056
nucleobase containing compound transport GO:0015931 56 0.056
ncrna processing GO:0034470 30 0.056
nls bearing protein import into nucleus GO:0006607 5 0.055
chromosome condensation GO:0030261 41 0.050
tissue death GO:0016271 102 0.049
appendage morphogenesis GO:0035107 397 0.048
regulation of cell cycle GO:0051726 291 0.047
nuclear envelope organization GO:0006998 7 0.047
centrosome organization GO:0051297 163 0.046
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.046
neurological system process GO:0050877 358 0.044
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.044
response to organic substance GO:0010033 284 0.044
mitotic spindle organization GO:0007052 220 0.044
Worm
dorsal ventral pattern formation GO:0009953 133 0.043
sex differentiation GO:0007548 81 0.043
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.043
mitotic cell cycle phase transition GO:0044772 138 0.042
centrosome cycle GO:0007098 137 0.042
g2 dna damage checkpoint GO:0031572 69 0.042
development of primary sexual characteristics GO:0045137 50 0.042
response to organonitrogen compound GO:0010243 75 0.041
rna transport GO:0050658 46 0.041
negative regulation of developmental process GO:0051093 201 0.040
regulation of phosphatase activity GO:0010921 3 0.040
modification dependent protein catabolic process GO:0019941 78 0.039
establishment of rna localization GO:0051236 47 0.039
regulation of cell cycle phase transition GO:1901987 130 0.038
response to oxygen containing compound GO:1901700 200 0.037
rrna processing GO:0006364 3 0.037
protein import GO:0017038 55 0.036
meiotic cell cycle GO:0051321 171 0.036
response to external biotic stimulus GO:0043207 293 0.035
regulation of mitotic cell cycle GO:0007346 190 0.035
protein import into nucleus GO:0006606 51 0.034
meiotic chromosome segregation GO:0045132 59 0.034
striated muscle cell development GO:0055002 50 0.034
microtubule organizing center organization GO:0031023 168 0.034
chaeta development GO:0022416 97 0.034
regulation of multi organism process GO:0043900 131 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.033
epithelial cell differentiation GO:0030855 322 0.032
programmed cell death GO:0012501 257 0.032
Worm
negative regulation of oskar mrna translation GO:0007319 5 0.032
maintenance of location GO:0051235 73 0.029
positive regulation of developmental process GO:0051094 143 0.029
oxoacid metabolic process GO:0043436 103 0.029
humoral immune response GO:0006959 117 0.028
protein localization GO:0008104 284 0.028
regulation of oocyte development GO:0060281 27 0.028
negative regulation of cell cycle phase transition GO:1901988 103 0.028
negative regulation of protein metabolic process GO:0051248 85 0.028
developmental programmed cell death GO:0010623 138 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
regulation of embryonic development GO:0045995 68 0.027
reproductive system development GO:0061458 74 0.027
mitotic spindle elongation GO:0000022 81 0.027
regulation of cell shape GO:0008360 113 0.027
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.026
negative regulation of transposition GO:0010529 12 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
cellular protein localization GO:0034613 160 0.025
nucleocytoplasmic transport GO:0006913 72 0.025
neuron projection guidance GO:0097485 241 0.025
nuclear import GO:0051170 51 0.025
covalent chromatin modification GO:0016569 106 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.024
cellular protein catabolic process GO:0044257 83 0.024
dna metabolic process GO:0006259 227 0.024
regulation of response to external stimulus GO:0032101 115 0.024
learning or memory GO:0007611 141 0.024
histone lysine demethylation GO:0070076 6 0.024
negative regulation of signal transduction GO:0009968 206 0.023
regulation of protein import into nucleus GO:0042306 28 0.023
positive regulation of cell proliferation GO:0008284 47 0.023
organic acid metabolic process GO:0006082 103 0.023
negative regulation of transcription dna templated GO:0045892 237 0.022
single organism behavior GO:0044708 391 0.022
muscle system process GO:0003012 21 0.022
wing disc morphogenesis GO:0007472 344 0.022
regulation of meiotic cell cycle GO:0051445 9 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
cell death GO:0008219 279 0.021
Worm
intracellular signal transduction GO:0035556 300 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.021
vesicle mediated transport GO:0016192 381 0.021
regulation of actin filament based process GO:0032970 42 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
cell cycle phase transition GO:0044770 140 0.020
regulation of transposition GO:0010528 13 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
lipid metabolic process GO:0006629 121 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
regulation of rna splicing GO:0043484 69 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
alternative mrna splicing via spliceosome GO:0000380 60 0.020
tissue morphogenesis GO:0048729 297 0.020
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.020
wound healing GO:0042060 75 0.019
protein catabolic process GO:0030163 101 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
response to abiotic stimulus GO:0009628 341 0.019
protein polyubiquitination GO:0000209 11 0.019
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
positive regulation of signaling GO:0023056 243 0.018
mitotic cell cycle embryonic GO:0045448 38 0.018
phagocytosis GO:0006909 215 0.018
dna conformation change GO:0071103 105 0.018
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
regulation of transcription factor import into nucleus GO:0042990 22 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
chromosome organization GO:0051276 360 0.017
genitalia development GO:0048806 26 0.017
morphogenesis of an epithelium GO:0002009 276 0.016
nuclear transport GO:0051169 72 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
chromatin modification GO:0016568 147 0.016
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.016
rna splicing GO:0008380 83 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
mitotic dna damage checkpoint GO:0044773 74 0.015
rna interference GO:0016246 27 0.015
synapse assembly GO:0007416 143 0.015
protein targeting GO:0006605 64 0.015
cytoplasmic mrna processing body assembly GO:0033962 10 0.015
Human
gonad development GO:0008406 50 0.015
response to endogenous stimulus GO:0009719 119 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
regulation of organelle organization GO:0033043 196 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.014
response to nitrogen compound GO:1901698 90 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
nucleic acid transport GO:0050657 46 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
reproductive structure development GO:0048608 74 0.014
antimicrobial humoral response GO:0019730 99 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
germ line cyst formation GO:0048134 44 0.013
dna packaging GO:0006323 91 0.013
transposition rna mediated GO:0032197 3 0.013
positive regulation of transport GO:0051050 92 0.013
regulation of protein export from nucleus GO:0046825 3 0.012
proteolysis GO:0006508 192 0.012
regulation of oskar mrna translation GO:0046011 8 0.012
multi organism reproductive behavior GO:0044705 121 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
maintenance of protein location in cell GO:0032507 26 0.012
regulation of protein complex assembly GO:0043254 42 0.012
stem cell development GO:0048864 79 0.012
axon choice point recognition GO:0016198 26 0.012
germarium derived oocyte fate determination GO:0007294 26 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
establishment of protein localization GO:0045184 163 0.012
cellular response to radiation GO:0071478 52 0.011
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
negative regulation of cell cycle GO:0045786 116 0.011
germarium derived oocyte differentiation GO:0030706 29 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
histone h3 k9 modification GO:0061647 12 0.011
response to temperature stimulus GO:0009266 106 0.011
long term memory GO:0007616 62 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
defense response GO:0006952 300 0.011
establishment of ommatidial planar polarity GO:0042067 49 0.011
regulation of cell differentiation GO:0045595 302 0.011
cellular response to light stimulus GO:0071482 37 0.010
female germ line cyst formation GO:0048135 42 0.010
head development GO:0060322 135 0.010
positive regulation of cell cycle GO:0045787 43 0.010
growth GO:0040007 359 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
peptide metabolic process GO:0006518 80 0.010
muscle cell differentiation GO:0042692 103 0.010
regulation of actin filament polymerization GO:0030833 25 0.010
meiotic nuclear division GO:0007126 151 0.010
meiotic chromosome condensation GO:0010032 3 0.010
regulation of cellular response to stress GO:0080135 89 0.010

tral disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
benign neoplasm DOID:0060072 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014