Drosophila melanogaster

0 known processes

Takl1 (Dmel_CG31421)

Tak1-like 1

(Aliases: anon-AE003732.1,CG31421,Dmel\CG31421,TAKL1)

Takl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.040
organonitrogen compound metabolic process GO:1901564 318 0.038
Fly
wing disc morphogenesis GO:0007472 344 0.038
Fly
appendage development GO:0048736 401 0.038
response to abiotic stimulus GO:0009628 341 0.037
organic acid metabolic process GO:0006082 103 0.036
vesicle mediated transport GO:0016192 381 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.035
catabolic process GO:0009056 409 0.035
Fly
appendage morphogenesis GO:0035107 397 0.034
xenobiotic catabolic process GO:0042178 1 0.034
imaginal disc derived appendage development GO:0048737 399 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
response to biotic stimulus GO:0009607 294 0.033
Fly
oxoacid metabolic process GO:0043436 103 0.032
endocytosis GO:0006897 310 0.031
response to external biotic stimulus GO:0043207 293 0.031
Fly
cellular catabolic process GO:0044248 372 0.030
Fly
carboxylic acid metabolic process GO:0019752 92 0.030
hormone catabolic process GO:0042447 3 0.030
response to organic substance GO:0010033 284 0.030
Mouse Fly
response to other organism GO:0051707 293 0.029
Fly
body morphogenesis GO:0010171 2 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
organic substance catabolic process GO:1901575 308 0.029
single organism behavior GO:0044708 391 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
Human Mouse Rat Worm Fly
benzene containing compound metabolic process GO:0042537 3 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
Human Mouse Rat Worm Fly
intracellular signal transduction GO:0035556 300 0.026
Human Mouse Rat Worm Fly
phagocytosis GO:0006909 215 0.026
regionalization GO:0003002 416 0.026
defense response GO:0006952 300 0.026
Worm Fly
positive regulation of cell communication GO:0010647 250 0.026
Human Mouse Rat Worm Fly
response to oxygen containing compound GO:1901700 200 0.026
Fly
protein modification process GO:0036211 438 0.026
Human Mouse Rat Worm Fly
eye development GO:0001654 323 0.026
Fly
response to lipopolysaccharide GO:0032496 4 0.026
Fly
lateral inhibition GO:0046331 206 0.026
homeostatic process GO:0042592 199 0.025
cellular protein modification process GO:0006464 438 0.025
Human Mouse Rat Worm Fly
steroid catabolic process GO:0006706 1 0.025
single organism catabolic process GO:0044712 228 0.025
regulation of multicellular organismal development GO:2000026 414 0.024
negative regulation of gene expression GO:0010629 387 0.024
establishment of localization in cell GO:0051649 402 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
Mouse
organelle fission GO:0048285 340 0.024
positive regulation of signaling GO:0023056 243 0.024
Human Mouse Rat Worm Fly
nuclear division GO:0000280 332 0.023
death GO:0016265 284 0.023
Mouse Fly
organic substance transport GO:0071702 257 0.023
camera type eye development GO:0043010 4 0.022
positive regulation of signal transduction GO:0009967 223 0.022
Human Mouse Rat Worm Fly
positive regulation of biosynthetic process GO:0009891 316 0.022
Fly
neurological system process GO:0050877 358 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
androgen metabolic process GO:0008209 1 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
cell death GO:0008219 279 0.022
Mouse Fly
negative regulation of response to stimulus GO:0048585 258 0.022
Mouse
single organism biosynthetic process GO:0044711 206 0.021
cellular response to ethanol GO:0071361 4 0.021
regulation of localization GO:0032879 275 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.021
amine metabolic process GO:0009308 12 0.021
compound eye development GO:0048749 307 0.021
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
Fly
phosphorylation GO:0016310 294 0.020
Human Mouse Rat Worm Fly
forebrain development GO:0030900 2 0.020
positive regulation of gene expression GO:0010628 290 0.020
estrogen metabolic process GO:0008210 1 0.020
programmed cell death GO:0012501 257 0.020
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
response to bacterium GO:0009617 198 0.020
Fly
proteolysis GO:0006508 192 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
Human Mouse Rat Worm Fly
gland development GO:0048732 191 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
Human Mouse Rat Worm Fly
cellular amine metabolic process GO:0044106 12 0.020
protein localization GO:0008104 284 0.019
Worm
compound eye morphogenesis GO:0001745 249 0.019
Fly
ion transport GO:0006811 145 0.019
regulation of response to stress GO:0080134 200 0.019
Human Mouse Fly
cellular response to chemical stimulus GO:0070887 199 0.019
Mouse Fly
cell proliferation GO:0008283 299 0.019
epithelial cell differentiation GO:0030855 322 0.019
actin filament based process GO:0030029 220 0.019
sensory organ morphogenesis GO:0090596 260 0.019
Fly
connective tissue development GO:0061448 3 0.019
response to radiation GO:0009314 155 0.019
regulation of protein metabolic process GO:0051246 256 0.018
Human Mouse Rat Worm Fly
regulation of cell cycle GO:0051726 291 0.018
cellular ketone metabolic process GO:0042180 24 0.018
kidney development GO:0001822 3 0.018
sterol homeostasis GO:0055092 4 0.018
sensory perception of chemical stimulus GO:0007606 116 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
tissue morphogenesis GO:0048729 297 0.018
Mouse Fly
carbohydrate derivative metabolic process GO:1901135 217 0.017
negative regulation of cell communication GO:0010648 223 0.017
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
defense response to other organism GO:0098542 225 0.017
Fly
adult behavior GO:0030534 137 0.017
response to extracellular stimulus GO:0009991 116 0.017
regulation of molecular function GO:0065009 217 0.017
Human Mouse Rat Worm Fly
negative regulation of biosynthetic process GO:0009890 277 0.017
regulation of transport GO:0051049 181 0.017
negative regulation of developmental process GO:0051093 201 0.017
aromatic compound catabolic process GO:0019439 166 0.017
immune system process GO:0002376 347 0.017
Human Fly
response to organophosphorus GO:0046683 2 0.017
macromolecule catabolic process GO:0009057 161 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
Human Mouse Rat Worm Fly
response to monosaccharide GO:0034284 4 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
detection of stimulus GO:0051606 156 0.017
chaeta development GO:0022416 97 0.017
response to nutrient levels GO:0031667 114 0.017
epithelial cell development GO:0002064 274 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
eye morphogenesis GO:0048592 260 0.016
Fly
immune response GO:0006955 246 0.016
Human Fly
multi organism behavior GO:0051705 175 0.016
growth GO:0040007 359 0.016
response to starvation GO:0042594 97 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
mitotic nuclear division GO:0007067 213 0.016
developmental maturation GO:0021700 172 0.016
segmentation GO:0035282 207 0.016
developmental growth GO:0048589 280 0.016
macromolecular complex assembly GO:0065003 256 0.016
Mouse
negative regulation of signaling GO:0023057 219 0.016
Mouse
sensory perception of smell GO:0007608 80 0.016
developmental programmed cell death GO:0010623 138 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
Mouse Fly
negative regulation of signal transduction GO:0009968 206 0.016
Mouse
lipid metabolic process GO:0006629 121 0.016
response to hexose GO:0009746 3 0.016
intracellular transport GO:0046907 228 0.016
exocrine system development GO:0035272 162 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
taxis GO:0042330 304 0.016
regulation of catalytic activity GO:0050790 185 0.015
Human Mouse Rat Worm Fly
regulation of phosphorus metabolic process GO:0051174 210 0.015
Human Mouse Rat Worm Fly
chromosome organization GO:0051276 360 0.015
Human
sensory perception GO:0007600 196 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
organophosphate metabolic process GO:0019637 195 0.015
salivary gland development GO:0007431 162 0.015
defense response to bacterium GO:0042742 178 0.015
Fly
response to glucose GO:0009749 2 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
cellular macromolecule localization GO:0070727 220 0.015
regulation of cell differentiation GO:0045595 302 0.015
anatomical structure homeostasis GO:0060249 97 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
positive regulation of cell migration GO:0030335 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
localization of cell GO:0051674 257 0.015
neuropeptide signaling pathway GO:0007218 45 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
synaptic transmission GO:0007268 288 0.015
salivary gland morphogenesis GO:0007435 145 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
establishment of protein localization GO:0045184 163 0.014
l amino acid import GO:0043092 2 0.014
regulation of cell cycle process GO:0010564 181 0.014
actin cytoskeleton organization GO:0030036 206 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of cell death GO:0010941 173 0.014
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.014
tube morphogenesis GO:0035239 191 0.014
Mouse Worm
gene silencing GO:0016458 138 0.014
transmembrane transport GO:0055085 139 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
response to nitrogen compound GO:1901698 90 0.014
apoptotic process GO:0006915 159 0.014
Mouse Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
cholesterol homeostasis GO:0042632 3 0.014
open tracheal system development GO:0007424 204 0.014
polyol biosynthetic process GO:0046173 3 0.014
regulation of catabolic process GO:0009894 170 0.014
Fly
protein transport GO:0015031 155 0.014
l glutamate import GO:0051938 1 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
cell division GO:0051301 248 0.014
Worm
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
Human Mouse Rat Worm Fly
locomotory behavior GO:0007626 176 0.014
regulation of organelle organization GO:0033043 196 0.014
ras protein signal transduction GO:0007265 88 0.014
response to organic cyclic compound GO:0014070 89 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
respiratory system development GO:0060541 213 0.014
response to light stimulus GO:0009416 124 0.014
spindle organization GO:0007051 253 0.014
response to endogenous stimulus GO:0009719 119 0.014
Mouse
regulation of programmed cell death GO:0043067 152 0.014
Mouse
regulation of cellular catabolic process GO:0031329 157 0.014
Fly
cation transport GO:0006812 110 0.014
chromosome segregation GO:0007059 157 0.013
cell motility GO:0048870 251 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
Human Mouse Rat Worm Fly
mitotic cell cycle phase transition GO:0044772 138 0.013
response to alcohol GO:0097305 95 0.013
gland morphogenesis GO:0022612 145 0.013
tube development GO:0035295 244 0.013
Mouse Worm
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
protein phosphorylation GO:0006468 169 0.013
Human Mouse Rat Worm Fly
positive regulation of molecular function GO:0044093 136 0.013
Human Mouse Rat Worm Fly
limb development GO:0060173 1 0.013
regulation of developmental growth GO:0048638 174 0.013
telencephalon development GO:0021537 2 0.013
hindbrain development GO:0030902 2 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
ovarian follicle cell development GO:0030707 248 0.013
tissue death GO:0016271 102 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
Human Mouse Rat Worm Fly
ethanolamine containing compound metabolic process GO:0042439 4 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
regulation of immune system process GO:0002682 176 0.013
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.013
positive regulation of cell motility GO:2000147 3 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
endomembrane system organization GO:0010256 119 0.013
regulation of cellular localization GO:0060341 136 0.013
histolysis GO:0007559 102 0.013
axis specification GO:0009798 167 0.013
embryonic pattern specification GO:0009880 174 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
cell cycle phase transition GO:0044770 140 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
Fly
cellular homeostasis GO:0019725 80 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of cellular response to stress GO:0080135 89 0.013
Human Mouse Fly
central nervous system development GO:0007417 201 0.013
chromatin organization GO:0006325 207 0.013
Human
mesenchymal cell differentiation GO:0048762 1 0.013
regulation of cell development GO:0060284 215 0.013
response to temperature stimulus GO:0009266 106 0.012
male gamete generation GO:0048232 201 0.012
ion transmembrane transport GO:0034220 122 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
aggressive behavior GO:0002118 63 0.012
chemotaxis GO:0006935 249 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
Human Mouse Rat Worm Fly
response to copper ion GO:0046688 4 0.012
camera type eye morphogenesis GO:0048593 2 0.012
salivary gland histolysis GO:0035070 88 0.012
protein complex biogenesis GO:0070271 201 0.012
Mouse
regulation of anatomical structure size GO:0090066 163 0.012
multicellular organismal aging GO:0010259 140 0.012
regulation of nervous system development GO:0051960 248 0.012
cellular response to organic substance GO:0071310 132 0.012
Mouse Fly
embryonic morphogenesis GO:0048598 206 0.012
Mouse Worm Fly
cytoplasmic transport GO:0016482 130 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
Human Mouse Rat Worm Fly
autophagic cell death GO:0048102 83 0.012
dna metabolic process GO:0006259 227 0.012
protein complex assembly GO:0006461 200 0.012
Mouse
purine nucleotide metabolic process GO:0006163 146 0.012
rna processing GO:0006396 147 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
Fly
spermatogenesis GO:0007283 200 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
photoreceptor cell development GO:0042461 96 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
Fly
mitotic spindle organization GO:0007052 220 0.012
regulation of multi organism process GO:0043900 131 0.012
Fly
digestive tract development GO:0048565 149 0.012
Worm
salivary gland cell autophagic cell death GO:0035071 83 0.012
anion homeostasis GO:0055081 3 0.012
carbohydrate metabolic process GO:0005975 82 0.012
multi multicellular organism process GO:0044706 123 0.012
aging GO:0007568 143 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
single organism cellular localization GO:1902580 180 0.012
monocarboxylic acid transport GO:0015718 3 0.012
cellular protein localization GO:0034613 160 0.012
immune response activating signal transduction GO:0002757 2 0.012
pigmentation GO:0043473 75 0.012
ameboidal type cell migration GO:0001667 151 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
purine containing compound metabolic process GO:0072521 155 0.012
regulation of proteolysis GO:0030162 87 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
nephron tubule development GO:0072080 3 0.011
positive regulation of catabolic process GO:0009896 105 0.011
synapse organization GO:0050808 196 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
mesenchymal cell development GO:0014031 1 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
innate immune response GO:0045087 144 0.011
digestive system development GO:0055123 149 0.011
Worm
cell migration GO:0016477 238 0.011
positive regulation of lipid storage GO:0010884 4 0.011
actin filament organization GO:0007015 126 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
Fly
regulation of apoptotic process GO:0042981 130 0.011
Mouse
defense response to gram negative bacterium GO:0050829 94 0.011
Fly
blastoderm segmentation GO:0007350 159 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
Human Mouse Rat
vitamin biosynthetic process GO:0009110 1 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
Human Mouse Rat Worm Fly
regulation of immune response GO:0050776 118 0.011
Human Fly
limb morphogenesis GO:0035108 1 0.011
cuticle development GO:0042335 86 0.011
axon development GO:0061564 297 0.011
cation transmembrane transport GO:0098655 88 0.011
regulation of mapk cascade GO:0043408 92 0.011
Human Mouse Rat Worm Fly
mapk cascade GO:0000165 107 0.011
Human Mouse Rat Worm Fly
meiotic cell cycle GO:0051321 171 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
dendrite development GO:0016358 204 0.011
regulation of lipid transport GO:0032368 3 0.011
peptidyl amino acid modification GO:0018193 105 0.011
Human
regulation of phosphorylation GO:0042325 147 0.011
Human Mouse Rat Worm Fly
dendrite morphogenesis GO:0048813 199 0.011
detection of external stimulus GO:0009581 66 0.011
humoral immune response GO:0006959 117 0.011
Fly
chemical homeostasis GO:0048878 92 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
developmental pigmentation GO:0048066 68 0.011
protein catabolic process GO:0030163 101 0.011
secretion GO:0046903 109 0.011
cell adhesion GO:0007155 136 0.011
regulation of hydrolase activity GO:0051336 97 0.011
neuron projection guidance GO:0097485 241 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
biological adhesion GO:0022610 138 0.011
regulation of cell proliferation GO:0042127 163 0.011
leg disc development GO:0035218 92 0.011
regulation of response to external stimulus GO:0032101 115 0.011
Fly
imaginal disc pattern formation GO:0007447 91 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
cell recognition GO:0008037 102 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
cell maturation GO:0048469 144 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
nitrogen compound transport GO:0071705 85 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
acylglycerol catabolic process GO:0046464 3 0.010
rna localization GO:0006403 115 0.010
organelle assembly GO:0070925 198 0.010
autophagy GO:0006914 108 0.010
Fly
metal ion transport GO:0030001 74 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
determination of adult lifespan GO:0008340 137 0.010
leg disc morphogenesis GO:0007478 80 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
negative regulation of cell cycle GO:0045786 116 0.010
protein processing GO:0016485 68 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
notch signaling pathway GO:0007219 120 0.010
cell cycle checkpoint GO:0000075 95 0.010
axon guidance GO:0007411 233 0.010
axonogenesis GO:0007409 290 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
wnt signaling pathway GO:0016055 98 0.010

Takl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.014
cardiovascular system disease DOID:1287 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
diabetes mellitus DOID:9351 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
urinary system disease DOID:18 0 0.011
type 2 diabetes mellitus DOID:9352 0 0.011
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010
eye and adnexa disease DOID:1492 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
eye disease DOID:5614 0 0.010