Drosophila melanogaster

103 known processes

Nrx-1 (Dmel_CG7050)

Neurexin 1

(Aliases: dnrx,Nrx1,Dmel\CG7050,nrx,Nrx,dnrx-1,CG7050,CT21808)

Nrx-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 1.000
synapse organization GO:0050808 196 0.997
regulation of synaptic transmission GO:0050804 69 0.979
neuromuscular synaptic transmission GO:0007274 67 0.957
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.952
g protein coupled receptor signaling pathway GO:0007186 136 0.947
neuromuscular junction development GO:0007528 149 0.931
synaptic vesicle recycling GO:0036465 28 0.925
regulation of synapse organization GO:0050807 110 0.862
establishment of localization in cell GO:0051649 402 0.861
neuron neuron synaptic transmission GO:0007270 14 0.853
Mouse
regulation of synapse structure and activity GO:0050803 128 0.791
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.759
synaptic growth at neuromuscular junction GO:0051124 119 0.747
learning or memory GO:0007611 141 0.722
axonogenesis GO:0007409 290 0.711
Zebrafish
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.708
synaptic transmission glutamatergic GO:0035249 7 0.692
Mouse
single organism membrane fusion GO:0044801 42 0.689
associative learning GO:0008306 65 0.680
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.670
Mouse
regulation of multicellular organismal development GO:2000026 414 0.641
Mouse
synaptic vesicle exocytosis GO:0016079 16 0.636
developmental growth GO:0048589 280 0.628
positive regulation of synaptic transmission GO:0050806 15 0.613
regulation of neurotransmitter levels GO:0001505 38 0.588
Mouse
signal release GO:0023061 49 0.559
Mouse
establishment of vesicle localization GO:0051650 51 0.544
positive regulation of cellular component organization GO:0051130 156 0.542
growth GO:0040007 359 0.481
regulation of neuromuscular synaptic transmission GO:1900073 15 0.473
synapse assembly GO:0007416 143 0.461
cognition GO:0050890 141 0.453
synaptic vesicle endocytosis GO:0048488 28 0.448
regulation of neurotransmitter secretion GO:0046928 14 0.445
calcium ion homeostasis GO:0055074 23 0.410
cellular protein modification process GO:0006464 438 0.406
locomotory behavior GO:0007626 176 0.397
dendrite morphogenesis GO:0048813 199 0.363
single organism behavior GO:0044708 391 0.345
synaptic vesicle transport GO:0048489 50 0.343
regulation of synapse assembly GO:0051963 94 0.340
Mouse
cyclic purine nucleotide metabolic process GO:0052652 25 0.336
establishment of synaptic vesicle localization GO:0097480 50 0.325
rhythmic synaptic transmission GO:0060024 2 0.325
neurotransmitter transport GO:0006836 37 0.321
Mouse
neurotransmitter secretion GO:0007269 35 0.320
Mouse
metal ion homeostasis GO:0055065 44 0.319
regulation of terminal button organization GO:2000331 11 0.318
regulation of vesicle mediated transport GO:0060627 59 0.302
regulation of localization GO:0032879 275 0.298
positive regulation of neurotransmitter transport GO:0051590 2 0.284
membrane fusion GO:0061025 42 0.272
regulation of phosphate metabolic process GO:0019220 210 0.271
small molecule metabolic process GO:0044281 305 0.260
axon guidance GO:0007411 233 0.252
Zebrafish
negative regulation of developmental process GO:0051093 201 0.246
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.243
terminal button organization GO:0072553 19 0.242
regulation of cellular localization GO:0060341 136 0.236
adult locomotory behavior GO:0008344 76 0.234
regulation of tube size GO:0035150 46 0.228
regulation of synaptic transmission glutamatergic GO:0051966 5 0.228
Mouse
positive regulation of cellular component biogenesis GO:0044089 80 0.222
Mouse
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.209
ion transmembrane transport GO:0034220 122 0.205
Mouse
single organism membrane organization GO:0044802 93 0.202
cell growth GO:0016049 108 0.201
regulation of endocytosis GO:0030100 37 0.199
secretion GO:0046903 109 0.195
Mouse
positive regulation of neurotransmitter secretion GO:0001956 2 0.194
secretion by cell GO:0032940 101 0.190
Mouse
positive regulation of signaling GO:0023056 243 0.189
organelle fusion GO:0048284 46 0.187
cation homeostasis GO:0055080 51 0.186
positive regulation of secretion GO:0051047 22 0.183
regulation of cellular component biogenesis GO:0044087 201 0.181
Mouse
rhythmic excitation GO:0043179 1 0.180
regulation of secretion GO:0051046 44 0.177
Mouse
vesicle localization GO:0051648 55 0.176
divalent inorganic cation homeostasis GO:0072507 29 0.176
learning GO:0007612 75 0.176
negative regulation of synapse assembly GO:0051964 39 0.176
axon development GO:0061564 297 0.174
Zebrafish
purine containing compound metabolic process GO:0072521 155 0.164
organelle localization GO:0051640 148 0.164
positive regulation of nervous system development GO:0051962 69 0.161
Mouse
establishment of protein localization GO:0045184 163 0.161
Mouse
regulation of system process GO:0044057 36 0.152
negative regulation of growth GO:0045926 84 0.152
purine ribonucleotide biosynthetic process GO:0009152 28 0.151
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.150
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.150
neuron projection guidance GO:0097485 241 0.149
Zebrafish
regulation of organelle organization GO:0033043 196 0.149
single organism biosynthetic process GO:0044711 206 0.147
developmental maturation GO:0021700 172 0.146
Mouse
protein complex biogenesis GO:0070271 201 0.145
Mouse
regulation of synaptic vesicle endocytosis GO:1900242 7 0.141
taxis GO:0042330 304 0.141
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.140
regulation of growth GO:0040008 233 0.140
negative regulation of cellular component organization GO:0051129 108 0.135
Mouse
immune system process GO:0002376 347 0.134
regulation of synaptic vesicle exocytosis GO:2000300 3 0.133
regulation of synaptic plasticity GO:0048167 14 0.131
motor neuron axon guidance GO:0008045 58 0.130
Zebrafish
regulation of neurogenesis GO:0050767 158 0.128
organophosphate metabolic process GO:0019637 195 0.128
vesicle mediated transport GO:0016192 381 0.127
cellular macromolecule localization GO:0070727 220 0.126
Mouse
response to radiation GO:0009314 155 0.126
immune response GO:0006955 246 0.125
positive regulation of synapse assembly GO:0051965 29 0.125
Mouse
regulation of secretion by cell GO:1903530 39 0.124
Mouse
ribonucleotide metabolic process GO:0009259 145 0.122
negative regulation of biosynthetic process GO:0009890 277 0.121
chemotaxis GO:0006935 249 0.120
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 316 0.117
protein localization GO:0008104 284 0.115
Mouse
organic substance catabolic process GO:1901575 308 0.114
regulation of nervous system development GO:0051960 248 0.114
Mouse
ribose phosphate biosynthetic process GO:0046390 28 0.114
positive regulation of transport GO:0051050 92 0.113
positive regulation of cell communication GO:0010647 250 0.111
chemical homeostasis GO:0048878 92 0.111
Mouse
purine containing compound biosynthetic process GO:0072522 30 0.110
regulation of cell development GO:0060284 215 0.110
cation transport GO:0006812 110 0.109
Mouse
regulation of transport GO:0051049 181 0.108
cellular ion homeostasis GO:0006873 39 0.108
regulation of transmembrane transport GO:0034762 27 0.107
Mouse
positive regulation of synaptic vesicle recycling GO:1903423 4 0.106
single organismal cell cell adhesion GO:0016337 45 0.105
Mouse
positive regulation of cell migration GO:0030335 2 0.103
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.103
nucleobase containing small molecule metabolic process GO:0055086 174 0.103
cell maturation GO:0048469 144 0.102
Mouse
cellular catabolic process GO:0044248 372 0.101
cell death GO:0008219 279 0.101
ribonucleotide biosynthetic process GO:0009260 28 0.100
regulation of neurotransmitter transport GO:0051588 14 0.098
dendrite development GO:0016358 204 0.095
regulation of cell differentiation GO:0045595 302 0.095
membrane organization GO:0061024 112 0.094
negative regulation of nervous system development GO:0051961 92 0.093
divalent inorganic cation transport GO:0072511 30 0.092
Mouse
protein modification process GO:0036211 438 0.091
cell projection assembly GO:0030031 94 0.089
Mouse
catabolic process GO:0009056 409 0.088
cellular amino acid metabolic process GO:0006520 61 0.088
single organism intracellular transport GO:1902582 207 0.087
regulation of membrane potential GO:0042391 35 0.087
Mouse
response to nutrient levels GO:0031667 114 0.086
organonitrogen compound metabolic process GO:1901564 318 0.086
positive regulation of macromolecule metabolic process GO:0010604 405 0.086
protein transport GO:0015031 155 0.085
single organism cellular localization GO:1902580 180 0.084
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.083
social behavior GO:0035176 4 0.083
Human
purine ribonucleotide metabolic process GO:0009150 145 0.082
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.080
organic substance transport GO:0071702 257 0.080
regulation of developmental pigmentation GO:0048070 24 0.079
positive regulation of phosphorus metabolic process GO:0010562 139 0.079
phosphorylation GO:0016310 294 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.079
cell proliferation GO:0008283 299 0.078
regulation of exocytosis GO:0017157 6 0.078
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.078
endomembrane system organization GO:0010256 119 0.077
Mouse
maintenance of presynaptic active zone structure GO:0048790 8 0.077
developmental pigmentation GO:0048066 68 0.076
positive regulation of secretion by cell GO:1903532 20 0.075
filopodium assembly GO:0046847 33 0.075
Mouse
exocytosis GO:0006887 28 0.074
neuron maturation GO:0042551 31 0.073
Mouse
cellular ketone metabolic process GO:0042180 24 0.073
response to inorganic substance GO:0010035 44 0.073
inositol lipid mediated signaling GO:0048017 4 0.073
cytosolic calcium ion homeostasis GO:0051480 11 0.072
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.071
regulation of necrotic cell death GO:0010939 1 0.071
feeding behavior GO:0007631 50 0.071
negative regulation of cell communication GO:0010648 223 0.071
negative regulation of signaling GO:0023057 219 0.071
localization of cell GO:0051674 257 0.070
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.070
cellular protein localization GO:0034613 160 0.069
Mouse
regulation of protein metabolic process GO:0051246 256 0.069
positive regulation of exocytosis GO:0045921 4 0.069
phosphatidylinositol mediated signaling GO:0048015 4 0.068
cellular metal ion homeostasis GO:0006875 31 0.068
detection of light stimulus GO:0009583 58 0.068
response to starvation GO:0042594 97 0.068
positive regulation of multicellular organismal process GO:0051240 143 0.067
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.067
developmental programmed cell death GO:0010623 138 0.067
negative regulation of homeostatic process GO:0032845 2 0.067
single organism catabolic process GO:0044712 228 0.067
regulation of molecular function GO:0065009 217 0.066
Mouse
ion transport GO:0006811 145 0.066
Mouse
homeostatic process GO:0042592 199 0.065
Mouse
forebrain development GO:0030900 2 0.065
cell migration GO:0016477 238 0.065
regulation of sequestering of calcium ion GO:0051282 3 0.065
sensory perception of chemical stimulus GO:0007606 116 0.064
cellular cation homeostasis GO:0030003 38 0.064
cellular homeostasis GO:0019725 80 0.063
Mouse
regulation of protein phosphorylation GO:0001932 64 0.062
conditioned taste aversion GO:0001661 3 0.061
establishment of organelle localization GO:0051656 122 0.061
segmentation GO:0035282 207 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.060
sensory perception GO:0007600 196 0.060
carboxylic acid metabolic process GO:0019752 92 0.059
regulation of filopodium assembly GO:0051489 24 0.058
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.057
muscle contraction GO:0006936 13 0.057
developmental growth involved in morphogenesis GO:0060560 65 0.057
negative regulation of cellular metabolic process GO:0031324 382 0.057
cell adhesion GO:0007155 136 0.056
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 119 0.056
regulation of ion transport GO:0043269 39 0.056
Mouse
tube development GO:0035295 244 0.056
regulation of glutamate receptor signaling pathway GO:1900449 1 0.055
Mouse
glycosyl compound metabolic process GO:1901657 127 0.055
transcription from rna polymerase ii promoter GO:0006366 368 0.055
membrane depolarization GO:0051899 4 0.055
Mouse
calcium ion transport GO:0006816 24 0.055
Mouse
signal transduction by phosphorylation GO:0023014 107 0.055
multi organism behavior GO:0051705 175 0.054
Human
vesicle organization GO:0016050 44 0.054
regulation of protein kinase activity GO:0045859 51 0.054
dopamine receptor signaling pathway GO:0007212 4 0.053
regulation of reproductive process GO:2000241 54 0.053
visual learning GO:0008542 4 0.052
synaptic vesicle localization GO:0097479 53 0.052
regulation of phosphorylation GO:0042325 147 0.051
regulation of epithelial cell proliferation GO:0050678 4 0.051
regulation of synaptic vesicle transport GO:1902803 10 0.051
regulation of transferase activity GO:0051338 58 0.051
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.051
regulation of axonogenesis GO:0050770 32 0.051
oocyte differentiation GO:0009994 145 0.050
carbohydrate derivative catabolic process GO:1901136 118 0.050
response to ketone GO:1901654 34 0.050
response to ethanol GO:0045471 59 0.050
negative regulation of rna biosynthetic process GO:1902679 240 0.050
regulation of neuron differentiation GO:0045664 103 0.049
carbohydrate derivative biosynthetic process GO:1901137 85 0.049
positive regulation of mapk cascade GO:0043410 63 0.048
response to organic cyclic compound GO:0014070 89 0.048
pigmentation GO:0043473 75 0.048
regulation of anatomical structure size GO:0090066 163 0.048
purine ribonucleoside metabolic process GO:0046128 127 0.048
autophagy GO:0006914 108 0.048
response to external biotic stimulus GO:0043207 293 0.048
organic acid metabolic process GO:0006082 103 0.047
memory GO:0007613 94 0.047
blood circulation GO:0008015 26 0.047
purine ribonucleoside catabolic process GO:0046130 112 0.046
purine nucleotide metabolic process GO:0006163 146 0.046
nucleoside phosphate biosynthetic process GO:1901293 34 0.046
purine nucleotide catabolic process GO:0006195 109 0.046
enzyme linked receptor protein signaling pathway GO:0007167 179 0.046
regulation of catalytic activity GO:0050790 185 0.046
protein phosphorylation GO:0006468 169 0.046
cell junction organization GO:0034330 57 0.046
positive regulation of response to stimulus GO:0048584 323 0.045
cellular response to chemical stimulus GO:0070887 199 0.045
Mouse
single organism cell adhesion GO:0098602 47 0.044
Mouse
synaptic vesicle priming GO:0016082 1 0.044
regulation of olfactory learning GO:0090328 8 0.044
regulation of cell size GO:0008361 63 0.044
oxoacid metabolic process GO:0043436 103 0.044
positive regulation of developmental growth GO:0048639 62 0.044
regulation of cell cycle phase transition GO:1901987 130 0.043
negative regulation of neural precursor cell proliferation GO:2000178 27 0.043
muscle system process GO:0003012 21 0.043
response to oxidative stress GO:0006979 86 0.043
positive regulation of cell motility GO:2000147 3 0.043
nucleobase containing compound catabolic process GO:0034655 165 0.043
positive regulation of cell death GO:0010942 69 0.042
regulation of cell morphogenesis GO:0022604 163 0.042
regulation of protein modification process GO:0031399 112 0.042
positive regulation of phosphate metabolic process GO:0045937 139 0.042
larval behavior GO:0030537 42 0.042
developmental cell growth GO:0048588 52 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.041
cellular divalent inorganic cation homeostasis GO:0072503 23 0.041
response to temperature stimulus GO:0009266 106 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.041
ion homeostasis GO:0050801 55 0.041
negative regulation of response to stimulus GO:0048585 258 0.041
Mouse
nucleotide biosynthetic process GO:0009165 34 0.041
myotube differentiation GO:0014902 46 0.041
positive regulation of cell development GO:0010720 61 0.041
positive regulation of molecular function GO:0044093 136 0.041
neurotransmitter metabolic process GO:0042133 2 0.041
ribonucleoside triphosphate metabolic process GO:0009199 119 0.040
glial cell differentiation GO:0010001 35 0.040
positive regulation of axon guidance GO:1902669 1 0.040
neuron projection extension GO:1990138 32 0.040
open tracheal system development GO:0007424 204 0.040
regulation of protein serine threonine kinase activity GO:0071900 25 0.039
olfactory learning GO:0008355 56 0.039
negative regulation of signal transduction GO:0009968 206 0.039
intracellular transport GO:0046907 228 0.039
regulation of cell proliferation GO:0042127 163 0.039
response to hydrogen peroxide GO:0042542 11 0.039
cellular lipid metabolic process GO:0044255 83 0.039
regulation of neuronal synaptic plasticity GO:0048168 8 0.039
positive regulation of behavior GO:0048520 19 0.038
divalent metal ion transport GO:0070838 26 0.038
Mouse
amine metabolic process GO:0009308 12 0.038
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.038
actin cytoskeleton organization GO:0030036 206 0.038
cyclic nucleotide metabolic process GO:0009187 28 0.037
negative regulation of autophagy GO:0010507 16 0.037
lipid metabolic process GO:0006629 121 0.037
organonitrogen compound biosynthetic process GO:1901566 117 0.037
dopamine biosynthetic process GO:0042416 3 0.037
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.037
organophosphate catabolic process GO:0046434 112 0.037
hindgut morphogenesis GO:0007442 58 0.036
transmembrane transport GO:0055085 139 0.036
Mouse
pigment metabolic process GO:0042440 84 0.036
ameboidal type cell migration GO:0001667 151 0.036
regulation of synaptic activity GO:0060025 9 0.036
intracellular protein transport GO:0006886 104 0.036
purine nucleoside catabolic process GO:0006152 112 0.035
phenol containing compound metabolic process GO:0018958 57 0.035
cellular calcium ion homeostasis GO:0006874 21 0.035
negative regulation of cellular protein metabolic process GO:0032269 85 0.034
macromolecular complex assembly GO:0065003 256 0.034
Mouse
negative regulation of developmental growth GO:0048640 64 0.034
glycosyl compound catabolic process GO:1901658 112 0.034
positive regulation of nucleotide metabolic process GO:0045981 55 0.034
positive regulation of neuromuscular synaptic transmission GO:1900075 4 0.034
metal ion transport GO:0030001 74 0.033
Mouse
aging GO:0007568 143 0.033
cation transmembrane transport GO:0098655 88 0.033
Mouse
intracellular signal transduction GO:0035556 300 0.033
gtp metabolic process GO:0046039 72 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
nucleoside phosphate catabolic process GO:1901292 110 0.033
sensory organ morphogenesis GO:0090596 260 0.032
response to other organism GO:0051707 293 0.032
body morphogenesis GO:0010171 2 0.032
cellular amine metabolic process GO:0044106 12 0.032
regulation of gtp catabolic process GO:0033124 44 0.032
regulation of cell maturation GO:1903429 27 0.032
compound eye development GO:0048749 307 0.032
detection of visible light GO:0009584 38 0.032
regulation of actin filament based process GO:0032970 42 0.032
regionalization GO:0003002 416 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.032
cyclic nucleotide biosynthetic process GO:0009190 25 0.031
cellular chemical homeostasis GO:0055082 40 0.031
Mouse
programmed cell death GO:0012501 257 0.031
negative regulation of gene expression GO:0010629 387 0.031
regulation of developmental growth GO:0048638 174 0.031
response to light stimulus GO:0009416 124 0.031
axon extension GO:0048675 32 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
histone modification GO:0016570 106 0.031
ribonucleoside catabolic process GO:0042454 112 0.031
regulation of protein localization GO:0032880 76 0.030
Mouse
nucleotide metabolic process GO:0009117 161 0.030
response to organic substance GO:0010033 284 0.030
Mouse
positive regulation of developmental process GO:0051094 143 0.030
Mouse
long term memory GO:0007616 62 0.030
anterograde synaptic vesicle transport GO:0048490 3 0.030
synaptic transmission gabaergic GO:0051932 1 0.029
regulation of bmp signaling pathway GO:0030510 23 0.029
camera type eye morphogenesis GO:0048593 2 0.029
positive regulation of phosphorylation GO:0042327 87 0.029
regulation of behavior GO:0050795 75 0.029
Mouse
cellular protein complex assembly GO:0043623 71 0.028
positive regulation of nucleotide biosynthetic process GO:0030810 10 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
camera type eye development GO:0043010 4 0.028
cell recognition GO:0008037 102 0.028
positive regulation of signal transduction GO:0009967 223 0.028
embryonic pattern specification GO:0009880 174 0.028
aromatic compound catabolic process GO:0019439 166 0.028
rhythmic process GO:0048511 106 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
neuron recognition GO:0008038 101 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.028
blastoderm segmentation GO:0007350 159 0.028
positive regulation of cell differentiation GO:0045597 64 0.027
mitochondrion organization GO:0007005 65 0.027
regulation of cell death GO:0010941 173 0.027
pathway restricted smad protein phosphorylation GO:0060389 1 0.027
short term memory GO:0007614 19 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
cortical cytoskeleton organization GO:0030865 29 0.027
digestive tract development GO:0048565 149 0.027
rho protein signal transduction GO:0007266 14 0.027
brain development GO:0007420 120 0.027
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
muscle organ development GO:0007517 127 0.027
eye development GO:0001654 323 0.027
organophosphate biosynthetic process GO:0090407 46 0.026
anatomical structure homeostasis GO:0060249 97 0.026
camp metabolic process GO:0046058 19 0.026
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
peptidyl amino acid modification GO:0018193 105 0.026
macromolecule catabolic process GO:0009057 161 0.026
vesicle fusion GO:0006906 19 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
regulation of immune system process GO:0002682 176 0.026
morphogenesis of an epithelium GO:0002009 276 0.025
neuron cell cell adhesion GO:0007158 1 0.025
Mouse
stem cell division GO:0017145 69 0.025
death GO:0016265 284 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
regulation of ion transmembrane transport GO:0034765 27 0.025
Mouse
protein targeting GO:0006605 64 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
response to bacterium GO:0009617 198 0.024
mitochondrial fusion GO:0008053 7 0.024
regulation of cell projection assembly GO:0060491 30 0.024
Mouse
cellular nitrogen compound catabolic process GO:0044270 165 0.024
nucleoside catabolic process GO:0009164 112 0.024
detection of external stimulus GO:0009581 66 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
positive regulation of gtp catabolic process GO:0033126 43 0.023
detection of stimulus GO:0051606 156 0.023
regulation of feeding behavior GO:0060259 16 0.023
protein catabolic process GO:0030163 101 0.023
regulation of cellular component size GO:0032535 98 0.023
inorganic cation transmembrane transport GO:0098662 61 0.023
Mouse
eye morphogenesis GO:0048592 260 0.023
endocytosis GO:0006897 310 0.023
negative regulation of synaptic transmission GO:0050805 12 0.023
protein heterooligomerization GO:0051291 4 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
phagocytosis GO:0006909 215 0.022
molting cycle chitin based cuticle GO:0007591 56 0.022
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.022
response to abiotic stimulus GO:0009628 341 0.022
Human
bmp signaling pathway GO:0030509 27 0.022
regulation of actin cytoskeleton organization GO:0032956 42 0.022
protein kinase a signaling GO:0010737 2 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
cellular response to organic substance GO:0071310 132 0.021
Mouse
inorganic ion transmembrane transport GO:0098660 73 0.021
Mouse
response to extracellular stimulus GO:0009991 116 0.021
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.021
membrane biogenesis GO:0044091 8 0.021
maternal determination of anterior posterior axis embryo GO:0008358 74 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of protein complex assembly GO:0043254 42 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
negative regulation of cell development GO:0010721 62 0.020
telencephalon development GO:0021537 2 0.020
defense response GO:0006952 300 0.020
negative regulation of cellular response to oxidative stress GO:1900408 1 0.020
cytosolic calcium ion transport GO:0060401 2 0.020
negative regulation of peptide secretion GO:0002792 1 0.020
regulation of cellular response to growth factor stimulus GO:0090287 13 0.020
actin mediated cell contraction GO:0070252 21 0.020
positive regulation of immune system process GO:0002684 68 0.020
actin filament based process GO:0030029 220 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
gland development GO:0048732 191 0.019
hindbrain development GO:0030902 2 0.019
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
positive regulation of gene expression GO:0010628 290 0.019
epidermal growth factor receptor signaling pathway GO:0007173 58 0.019
response to wounding GO:0009611 94 0.019
purine ribonucleotide catabolic process GO:0009154 109 0.019
regulation of catabolic process GO:0009894 170 0.019
regulation of mapk cascade GO:0043408 92 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
circulatory system process GO:0003013 37 0.019
anterior posterior axis specification GO:0009948 109 0.019
regulation of intracellular transport GO:0032386 64 0.019
positive regulation of growth GO:0045927 75 0.019
positive regulation of cgmp metabolic process GO:0030825 1 0.019
regulation of lyase activity GO:0051339 14 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
cytoskeletal matrix organization at active zone GO:0048789 5 0.019
extracellular structure organization GO:0043062 46 0.019

Nrx-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.368
cancer DOID:162 0 0.041
disease of cellular proliferation DOID:14566 0 0.041
organ system cancer DOID:0050686 0 0.041
cardiovascular system disease DOID:1287 0 0.041
nervous system disease DOID:863 0 0.025