Drosophila melanogaster

80 known processes

Set2 (Dmel_CG1716)

CG1716 gene product from transcript CG1716-RA

(Aliases: dSet2,dHypb,set2,CG1716,Dmel\CG1716,Hypb)

Set2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification process GO:0036211 438 0.331
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.300
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.299
body morphogenesis GO:0010171 2 0.257
negative regulation of rna biosynthetic process GO:1902679 240 0.241
positive regulation of macromolecule metabolic process GO:0010604 405 0.188
centrosome cycle GO:0007098 137 0.141
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.139
mrna metabolic process GO:0016071 124 0.129
cellular protein modification process GO:0006464 438 0.127
transcription from rna polymerase ii promoter GO:0006366 368 0.124
Human
rna catabolic process GO:0006401 37 0.122
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.117
growth GO:0040007 359 0.116
regulation of notch signaling pathway GO:0008593 100 0.106
cell cycle phase transition GO:0044770 140 0.100
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.095
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.085
positive regulation of cellular biosynthetic process GO:0031328 316 0.082
mitotic g2 dna damage checkpoint GO:0007095 69 0.081
regulation of cell cycle GO:0051726 291 0.074
positive regulation of transcription dna templated GO:0045893 266 0.072
negative regulation of response to stimulus GO:0048585 258 0.068
vesicle mediated transport GO:0016192 381 0.067
positive regulation of rna biosynthetic process GO:1902680 266 0.067
positive regulation of biosynthetic process GO:0009891 316 0.066
negative regulation of developmental process GO:0051093 201 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.059
neuron projection guidance GO:0097485 241 0.058
negative regulation of rna metabolic process GO:0051253 251 0.056
negative regulation of cell differentiation GO:0045596 143 0.055
centrosome organization GO:0051297 163 0.053
chromosome organization GO:0051276 360 0.051
neural precursor cell proliferation GO:0061351 75 0.051
negative regulation of transcription dna templated GO:0045892 237 0.050
regionalization GO:0003002 416 0.049
positive regulation of cell communication GO:0010647 250 0.048
negative regulation of gene expression GO:0010629 387 0.048
negative regulation of notch signaling pathway GO:0045746 41 0.048
larval development GO:0002164 104 0.047
positive regulation of nucleic acid templated transcription GO:1903508 266 0.045
microtubule organizing center organization GO:0031023 168 0.042
response to biotic stimulus GO:0009607 294 0.042
negative regulation of signal transduction GO:0009968 206 0.041
regulation of mitotic cell cycle GO:0007346 190 0.039
endocytosis GO:0006897 310 0.039
negative regulation of cellular biosynthetic process GO:0031327 277 0.039
organelle localization GO:0051640 148 0.038
response to external biotic stimulus GO:0043207 293 0.036
stem cell proliferation GO:0072089 88 0.036
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.035
mitotic cell cycle checkpoint GO:0007093 88 0.035
dna integrity checkpoint GO:0031570 81 0.035
regulation of cell cycle phase transition GO:1901987 130 0.035
neurological system process GO:0050877 358 0.034
negative regulation of cell cycle process GO:0010948 109 0.033
regulation of cellular protein metabolic process GO:0032268 243 0.031
positive regulation of developmental growth GO:0048639 62 0.031
regulation of catalytic activity GO:0050790 185 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
negative regulation of cell cycle GO:0045786 116 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.029
notch signaling pathway GO:0007219 120 0.029
protein phosphorylation GO:0006468 169 0.028
regulation of phosphorylation GO:0042325 147 0.027
mrna processing GO:0006397 104 0.027
chromatin organization GO:0006325 207 0.026
positive regulation of rna metabolic process GO:0051254 271 0.026
determination of adult lifespan GO:0008340 137 0.026
mitotic dna integrity checkpoint GO:0044774 75 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
neuroblast proliferation GO:0007405 74 0.025
negative regulation of cell cycle phase transition GO:1901988 103 0.025
oocyte differentiation GO:0009994 145 0.024
cell cycle checkpoint GO:0000075 95 0.024
imaginal disc growth GO:0007446 37 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
regulation of protein modification process GO:0031399 112 0.023
regulation of cellular response to stress GO:0080135 89 0.023
phagocytosis GO:0006909 215 0.023
chromatin modification GO:0016568 147 0.023
regulation of mitotic cell cycle phase transition GO:1901990 130 0.023
establishment of organelle localization GO:0051656 122 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
modification dependent macromolecule catabolic process GO:0043632 79 0.021
appendage development GO:0048736 401 0.021
negative regulation of signaling GO:0023057 219 0.020
actin filament based process GO:0030029 220 0.020
nucleus organization GO:0006997 45 0.020
peptidyl proline modification GO:0018208 3 0.020
regulation of molecular function GO:0065009 217 0.020
g2 dna damage checkpoint GO:0031572 69 0.020
imaginal disc derived appendage development GO:0048737 399 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
connective tissue development GO:0061448 3 0.018
taxis GO:0042330 304 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.018
regulation of developmental growth GO:0048638 174 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.018
positive regulation of signaling GO:0023056 243 0.018
regulation of protein metabolic process GO:0051246 256 0.017
positive regulation of gene expression GO:0010628 290 0.017
regulation of protein serine threonine kinase activity GO:0071900 25 0.017
cellular catabolic process GO:0044248 372 0.017
regulation of multicellular organismal development GO:2000026 414 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.016
appendage morphogenesis GO:0035107 397 0.016
regulation of protein phosphorylation GO:0001932 64 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Mouse
catabolic process GO:0009056 409 0.016
regulation of purine nucleotide catabolic process GO:0033121 48 0.016
regulation of chromosome organization GO:0033044 64 0.016
response to oxidative stress GO:0006979 86 0.015
immune system process GO:0002376 347 0.015
male gamete generation GO:0048232 201 0.015
regulation of cell cycle process GO:0010564 181 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
negative regulation of translation GO:0017148 28 0.014
epithelial cell development GO:0002064 274 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.013
positive regulation of protein modification process GO:0031401 58 0.013
response to other organism GO:0051707 293 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
regulation of neural precursor cell proliferation GO:2000177 35 0.013
segmentation GO:0035282 207 0.013
organic substance catabolic process GO:1901575 308 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
translation GO:0006412 69 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cellular macromolecule catabolic process GO:0044265 136 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
chemotaxis GO:0006935 249 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
tissue morphogenesis GO:0048729 297 0.012
Mouse
response to organic substance GO:0010033 284 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
macromolecule catabolic process GO:0009057 161 0.011
endomembrane system organization GO:0010256 119 0.011
positive regulation of growth GO:0045927 75 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
mrna catabolic process GO:0006402 33 0.011
centrosome duplication GO:0051298 121 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
positive regulation of molecular function GO:0044093 136 0.011
blastoderm segmentation GO:0007350 159 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
negative regulation of neuron apoptotic process GO:0043524 14 0.010
nucleotide metabolic process GO:0009117 161 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010

Set2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.014