Drosophila melanogaster

16 known processes

CG12753 (Dmel_CG12753)

CG12753 gene product from transcript CG12753-RB

(Aliases: Dmel\CG12753)

CG12753 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.294
cellular protein modification process GO:0006464 438 0.155
synaptic vesicle recycling GO:0036465 28 0.151
catabolic process GO:0009056 409 0.142
synapse organization GO:0050808 196 0.131
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.128
cellular catabolic process GO:0044248 372 0.099
protein modification process GO:0036211 438 0.099
vesicle mediated transport GO:0016192 381 0.097
transcription from rna polymerase ii promoter GO:0006366 368 0.096
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.095
positive regulation of gene expression GO:0010628 290 0.094
positive regulation of response to stimulus GO:0048584 323 0.092
synaptic vesicle localization GO:0097479 53 0.087
endocytosis GO:0006897 310 0.082
synaptic vesicle endocytosis GO:0048488 28 0.081
intracellular transport GO:0046907 228 0.080
axonogenesis GO:0007409 290 0.079
regulation of multicellular organismal development GO:2000026 414 0.074
positive regulation of macromolecule metabolic process GO:0010604 405 0.071
organic substance catabolic process GO:1901575 308 0.069
positive regulation of biosynthetic process GO:0009891 316 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.068
regulation of cellular catabolic process GO:0031329 157 0.067
single organism catabolic process GO:0044712 228 0.062
regulation of cell death GO:0010941 173 0.060
organelle fusion GO:0048284 46 0.059
regulation of organelle organization GO:0033043 196 0.057
regulation of cellular component biogenesis GO:0044087 201 0.056
regionalization GO:0003002 416 0.054
positive regulation of rna metabolic process GO:0051254 271 0.054
organophosphate metabolic process GO:0019637 195 0.054
regulation of catabolic process GO:0009894 170 0.052
cell death GO:0008219 279 0.051
imaginal disc derived appendage development GO:0048737 399 0.051
tissue morphogenesis GO:0048729 297 0.048
neuron projection guidance GO:0097485 241 0.048
regulation of cell differentiation GO:0045595 302 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.045
death GO:0016265 284 0.045
cellular protein catabolic process GO:0044257 83 0.045
regulation of anatomical structure size GO:0090066 163 0.045
growth GO:0040007 359 0.045
chemotaxis GO:0006935 249 0.045
negative regulation of response to stimulus GO:0048585 258 0.044
dna damage checkpoint GO:0000077 78 0.043
membrane fusion GO:0061025 42 0.043
neurotransmitter secretion GO:0007269 35 0.042
cellular response to starvation GO:0009267 61 0.041
dendrite morphogenesis GO:0048813 199 0.041
purine nucleotide catabolic process GO:0006195 109 0.041
endosome to lysosome transport GO:0008333 7 0.040
locomotory behavior GO:0007626 176 0.040
synaptic vesicle transport GO:0048489 50 0.039
ribonucleoside catabolic process GO:0042454 112 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.039
positive regulation of nucleic acid templated transcription GO:1903508 266 0.039
carboxylic acid metabolic process GO:0019752 92 0.038
positive regulation of signaling GO:0023056 243 0.038
leg disc morphogenesis GO:0007478 80 0.038
establishment of localization in cell GO:0051649 402 0.038
synapse assembly GO:0007416 143 0.038
epithelium migration GO:0090132 148 0.038
organic substance transport GO:0071702 257 0.038
protein modification by small protein conjugation or removal GO:0070647 106 0.037
carbohydrate derivative catabolic process GO:1901136 118 0.037
regulation of phosphate metabolic process GO:0019220 210 0.037
regulation of hydrolase activity GO:0051336 97 0.036
regulation of synapse structure and activity GO:0050803 128 0.036
regulation of cell cycle GO:0051726 291 0.036
vesicle localization GO:0051648 55 0.035
protein modification by small protein conjugation GO:0032446 79 0.035
positive regulation of nucleotide catabolic process GO:0030813 46 0.035
positive regulation of catalytic activity GO:0043085 118 0.034
nucleoside catabolic process GO:0009164 112 0.034
regulation of molecular function GO:0065009 217 0.033
regulation of synaptic transmission GO:0050804 69 0.033
axon development GO:0061564 297 0.033
dna integrity checkpoint GO:0031570 81 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
purine ribonucleoside catabolic process GO:0046130 112 0.032
response to organic substance GO:0010033 284 0.032
establishment of synaptic vesicle localization GO:0097480 50 0.032
establishment of vesicle localization GO:0051650 51 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
lipid modification GO:0030258 24 0.032
regulation of programmed cell death GO:0043067 152 0.032
cellular macromolecule catabolic process GO:0044265 136 0.031
purine containing compound catabolic process GO:0072523 112 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
protein ubiquitination GO:0016567 70 0.031
single organism intracellular transport GO:1902582 207 0.031
ameboidal type cell migration GO:0001667 151 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
cell division GO:0051301 248 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.030
purine ribonucleoside metabolic process GO:0046128 127 0.030
taxis GO:0042330 304 0.029
positive regulation of signal transduction GO:0009967 223 0.029
g protein coupled receptor signaling pathway GO:0007186 136 0.029
ribonucleoside metabolic process GO:0009119 127 0.029
notch signaling pathway GO:0007219 120 0.029
proteasomal protein catabolic process GO:0010498 59 0.028
cation transport GO:0006812 110 0.028
modification dependent protein catabolic process GO:0019941 78 0.028
positive regulation of transcription dna templated GO:0045893 266 0.028
organophosphate catabolic process GO:0046434 112 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
immune system process GO:0002376 347 0.027
protein phosphorylation GO:0006468 169 0.027
regulation of neuron differentiation GO:0045664 103 0.027
establishment of organelle localization GO:0051656 122 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
regulation of multi organism process GO:0043900 131 0.027
intracellular signal transduction GO:0035556 300 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.027
positive regulation of hydrolase activity GO:0051345 78 0.026
chromosome organization GO:0051276 360 0.026
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
ribonucleoside triphosphate catabolic process GO:0009203 108 0.026
protein complex biogenesis GO:0070271 201 0.026
positive regulation of cell communication GO:0010647 250 0.025
oxoacid metabolic process GO:0043436 103 0.025
camera type eye development GO:0043010 4 0.025
autophagy GO:0006914 108 0.025
stem cell development GO:0048864 79 0.025
purine containing compound metabolic process GO:0072521 155 0.025
macromolecule catabolic process GO:0009057 161 0.024
compound eye development GO:0048749 307 0.024
negative regulation of signal transduction GO:0009968 206 0.024
macroautophagy GO:0016236 42 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
proteolysis GO:0006508 192 0.024
regulation of neurogenesis GO:0050767 158 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
tube development GO:0035295 244 0.023
gtp catabolic process GO:0006184 72 0.023
organelle localization GO:0051640 148 0.023
regulation of localization GO:0032879 275 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
protein complex assembly GO:0006461 200 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.023
positive regulation of cell death GO:0010942 69 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
phosphorylation GO:0016310 294 0.022
homeostatic process GO:0042592 199 0.022
cellular response to extracellular stimulus GO:0031668 64 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
single organism behavior GO:0044708 391 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
regulation of cell development GO:0060284 215 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
developmental growth GO:0048589 280 0.021
vesicle organization GO:0016050 44 0.021
regulation of catalytic activity GO:0050790 185 0.021
organic acid metabolic process GO:0006082 103 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
regulation of neurotransmitter levels GO:0001505 38 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
ras protein signal transduction GO:0007265 88 0.021
regulation of protein complex assembly GO:0043254 42 0.021
response to oxidative stress GO:0006979 86 0.021
positive regulation of cellular component organization GO:0051130 156 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
small molecule metabolic process GO:0044281 305 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
regulation of synapse organization GO:0050807 110 0.020
positive regulation of proteolysis GO:0045862 52 0.020
regulation of protein metabolic process GO:0051246 256 0.020
regulation of response to external stimulus GO:0032101 115 0.020
axon guidance GO:0007411 233 0.020
macromolecular complex assembly GO:0065003 256 0.020
eye development GO:0001654 323 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
dendrite development GO:0016358 204 0.020
purine nucleoside metabolic process GO:0042278 127 0.019
appendage morphogenesis GO:0035107 397 0.019
heterocycle catabolic process GO:0046700 166 0.019
regulation of response to stress GO:0080134 200 0.019
negative regulation of gene expression GO:0010629 387 0.019
branching morphogenesis of an epithelial tube GO:0048754 45 0.019
maintenance of location GO:0051235 73 0.019
cytoplasmic transport GO:0016482 130 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
gtp metabolic process GO:0046039 72 0.019
cell cycle checkpoint GO:0000075 95 0.019
spinal cord development GO:0021510 1 0.019
regulation of nucleotide metabolic process GO:0006140 62 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
positive regulation of programmed cell death GO:0043068 62 0.018
regulation of purine nucleotide catabolic process GO:0033121 48 0.018
leg disc development GO:0035218 92 0.018
mesenchymal cell development GO:0014031 1 0.018
endosomal transport GO:0016197 44 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
segmentation GO:0035282 207 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
retina development in camera type eye GO:0060041 4 0.018
negative regulation of cell communication GO:0010648 223 0.018
posttranscriptional gene silencing by rna GO:0035194 45 0.018
neuromuscular junction development GO:0007528 149 0.017
adult locomotory behavior GO:0008344 76 0.017
guanosine containing compound catabolic process GO:1901069 74 0.017
nuclear division GO:0000280 332 0.017
nucleotide catabolic process GO:0009166 109 0.017
protein catabolic process GO:0030163 101 0.017
ion transport GO:0006811 145 0.017
metal ion homeostasis GO:0055065 44 0.017
imaginal disc pattern formation GO:0007447 91 0.017
peptidyl amino acid modification GO:0018193 105 0.017
positive regulation of catabolic process GO:0009896 105 0.017
positive regulation of nucleotide metabolic process GO:0045981 55 0.017
cellular response to oxidative stress GO:0034599 28 0.017
response to abiotic stimulus GO:0009628 341 0.017
regulation of cellular response to oxidative stress GO:1900407 4 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
aromatic compound catabolic process GO:0019439 166 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
regulation of nucleotide catabolic process GO:0030811 48 0.016
response to starvation GO:0042594 97 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
connective tissue development GO:0061448 3 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
regulation of neuron death GO:1901214 26 0.016
oxidation reduction process GO:0055114 123 0.016
protein localization GO:0008104 284 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
regulation of cell proliferation GO:0042127 163 0.016
eye morphogenesis GO:0048592 260 0.016
developmental cell growth GO:0048588 52 0.016
ribonucleotide catabolic process GO:0009261 109 0.015
multicellular organismal aging GO:0010259 140 0.015
metal ion transport GO:0030001 74 0.015
cellular lipid metabolic process GO:0044255 83 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
cytokinesis GO:0000910 90 0.015
sensory perception of smell GO:0007608 80 0.015
regulation of lipid transport GO:0032368 3 0.015
tube morphogenesis GO:0035239 191 0.015
forebrain development GO:0030900 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
appendage development GO:0048736 401 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of response to oxidative stress GO:1902882 4 0.015
signal release GO:0023061 49 0.015
pupal development GO:0035209 11 0.015
chromatin remodeling GO:0006338 72 0.014
mushroom body development GO:0016319 70 0.014
regulation of cellular response to stress GO:0080135 89 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
regulation of proteolysis GO:0030162 87 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
limb development GO:0060173 1 0.014
negative regulation of signaling GO:0023057 219 0.014
negative regulation of neurogenesis GO:0050768 53 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
compound eye photoreceptor development GO:0042051 78 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
body morphogenesis GO:0010171 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 47 0.014
positive regulation of molecular function GO:0044093 136 0.014
regulation of endocytosis GO:0030100 37 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
single organism membrane organization GO:0044802 93 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
organelle membrane fusion GO:0090174 16 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
phagocytosis GO:0006909 215 0.013
positive regulation of lipid storage GO:0010884 4 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
bmp signaling pathway GO:0030509 27 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
amine metabolic process GO:0009308 12 0.013
water homeostasis GO:0030104 3 0.013
regulation of cell projection organization GO:0031344 92 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
response to lipopolysaccharide GO:0032496 4 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
telencephalon development GO:0021537 2 0.013
mapk cascade GO:0000165 107 0.013
neurotransmitter transport GO:0006836 37 0.013
cell proliferation GO:0008283 299 0.013
negative regulation of notch signaling pathway GO:0045746 41 0.013
endomembrane system organization GO:0010256 119 0.013
cellular response to organic substance GO:0071310 132 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
cellular response to nutrient levels GO:0031669 62 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
cellular response to reactive oxygen species GO:0034614 14 0.012
epithelial cell migration GO:0010631 148 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
response to organic cyclic compound GO:0014070 89 0.012
chemical homeostasis GO:0048878 92 0.012
single organism membrane fusion GO:0044801 42 0.012
regulation of nervous system development GO:0051960 248 0.012
peptidyl lysine modification GO:0018205 57 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
organelle fission GO:0048285 340 0.012
defense response to bacterium GO:0042742 178 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
regulation of growth GO:0040008 233 0.012
single organism cellular localization GO:1902580 180 0.012
response to endogenous stimulus GO:0009719 119 0.012
response to oxygen containing compound GO:1901700 200 0.012
microtubule based movement GO:0007018 51 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
cellular homeostasis GO:0019725 80 0.012
regulation of phosphorylation GO:0042325 147 0.011
cellular protein complex assembly GO:0043623 71 0.011
erbb signaling pathway GO:0038127 58 0.011
positive regulation of jun kinase activity GO:0043507 4 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
head development GO:0060322 135 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.011
response to extracellular stimulus GO:0009991 116 0.011
protein processing GO:0016485 68 0.011
regulation of synapse assembly GO:0051963 94 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
programmed cell death GO:0012501 257 0.011
muscle organ development GO:0007517 127 0.011
polyol biosynthetic process GO:0046173 3 0.011
regulation of gtpase activity GO:0043087 44 0.011
gene silencing by rna GO:0031047 57 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.011
regulation of lipid storage GO:0010883 22 0.011
covalent chromatin modification GO:0016569 106 0.011
wing disc pattern formation GO:0035222 66 0.011
lateral inhibition GO:0046331 206 0.011
negative regulation of bmp signaling pathway GO:0030514 12 0.011
cell growth GO:0016049 108 0.011
protein targeting GO:0006605 64 0.011
dephosphorylation GO:0016311 51 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
response to other organism GO:0051707 293 0.011
autophagic vacuole fusion GO:0000046 15 0.010
zymogen activation GO:0031638 20 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
gliogenesis GO:0042063 80 0.010
eye pigment granule organization GO:0008057 12 0.010
multicellular organismal homeostasis GO:0048871 41 0.010
regulation of apoptotic process GO:0042981 130 0.010
chromatin organization GO:0006325 207 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
response to biotic stimulus GO:0009607 294 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
anion homeostasis GO:0055081 3 0.010
regulation of transport GO:0051049 181 0.010
nicotinamide nucleotide metabolic process GO:0046496 2 0.010
myotube cell development GO:0014904 3 0.010
chromosome segregation GO:0007059 157 0.010

CG12753 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
cardiovascular system disease DOID:1287 0 0.086
hypertension DOID:10763 0 0.046
artery disease DOID:0050828 0 0.046
vascular disease DOID:178 0 0.046
essential hypertension DOID:10825 0 0.013
nervous system disease DOID:863 0 0.012