Drosophila melanogaster

38 known processes

sano (Dmel_CG12758)

serrano

(Aliases: CG12758,Dmel\CG12758)

sano biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of a polarized epithelium GO:0001738 93 0.961
establishment of planar polarity GO:0001736 87 0.919
establishment of tissue polarity GO:0007164 87 0.915
imaginal disc derived wing hair organization GO:0035317 45 0.850
tissue morphogenesis GO:0048729 297 0.829
imaginal disc derived appendage development GO:0048737 399 0.721
morphogenesis of an epithelium GO:0002009 276 0.669
compound eye morphogenesis GO:0001745 249 0.633
non sensory hair organization GO:0035316 47 0.615
epithelial cell migration GO:0010631 148 0.575
imaginal disc derived wing morphogenesis GO:0007476 337 0.570
regulation of multicellular organismal development GO:2000026 414 0.470
wing disc morphogenesis GO:0007472 344 0.412
establishment of ommatidial planar polarity GO:0042067 49 0.407
regulation of tube size open tracheal system GO:0035151 43 0.387
regulation of establishment of planar polarity GO:0090175 22 0.383
epithelial cell differentiation GO:0030855 322 0.343
imaginal disc derived appendage morphogenesis GO:0035114 395 0.307
eye development GO:0001654 323 0.288
post embryonic appendage morphogenesis GO:0035120 385 0.257
regulation of tube architecture open tracheal system GO:0035152 68 0.256
epithelium migration GO:0090132 148 0.240
appendage morphogenesis GO:0035107 397 0.218
regulation of tube size GO:0035150 46 0.202
hair cell differentiation GO:0035315 47 0.190
embryonic development via the syncytial blastoderm GO:0001700 148 0.186
embryonic morphogenesis GO:0048598 206 0.170
regulation of tube length open tracheal system GO:0035159 24 0.167
regulation of cell differentiation GO:0045595 302 0.159
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.159
eye morphogenesis GO:0048592 260 0.158
eye photoreceptor cell differentiation GO:0001754 145 0.158
epidermal cell differentiation GO:0009913 51 0.157
detection of light stimulus GO:0009583 58 0.149
ameboidal type cell migration GO:0001667 151 0.141
localization of cell GO:0051674 257 0.134
negative regulation of gene expression GO:0010629 387 0.127
compound eye photoreceptor fate commitment GO:0001752 36 0.116
imaginal disc derived wing hair site selection GO:0035320 4 0.115
sensory organ morphogenesis GO:0090596 260 0.114
ommatidial rotation GO:0016318 20 0.109
embryo development ending in birth or egg hatching GO:0009792 152 0.107
response to external biotic stimulus GO:0043207 293 0.106
tracheal outgrowth open tracheal system GO:0007426 18 0.105
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.104
regulation of protein metabolic process GO:0051246 256 0.103
vesicle mediated transport GO:0016192 381 0.102
establishment or maintenance of cell polarity GO:0007163 167 0.100
growth GO:0040007 359 0.097
photoreceptor cell differentiation GO:0046530 170 0.097
posttranscriptional gene silencing by rna GO:0035194 45 0.097
epidermis development GO:0008544 65 0.094
respiratory system development GO:0060541 213 0.093
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.091
gland development GO:0048732 191 0.087
establishment of body hair or bristle planar orientation GO:0048104 6 0.086
regulation of catabolic process GO:0009894 170 0.084
cytoplasmic transport GO:0016482 130 0.082
regulation of anatomical structure morphogenesis GO:0022603 242 0.082
defense response to other organism GO:0098542 225 0.082
morphogenesis of embryonic epithelium GO:0016331 94 0.081
negative regulation of signal transduction GO:0009968 206 0.080
branching involved in open tracheal system development GO:0060446 45 0.080
ovarian follicle cell development GO:0030707 248 0.080
negative regulation of cell communication GO:0010648 223 0.079
cell migration GO:0016477 238 0.078
organ growth GO:0035265 56 0.076
regulation of anatomical structure size GO:0090066 163 0.072
establishment of epithelial cell apical basal polarity GO:0045198 10 0.072
regulation of protein modification process GO:0031399 112 0.072
open tracheal system development GO:0007424 204 0.068
chromosome segregation GO:0007059 157 0.068
regulation of protein phosphorylation GO:0001932 64 0.067
meiotic cell cycle GO:0051321 171 0.067
response to biotic stimulus GO:0009607 294 0.066
photoreceptor cell fate commitment GO:0046552 41 0.064
phosphorylation GO:0016310 294 0.064
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.064
positive regulation of macromolecule metabolic process GO:0010604 405 0.061
negative regulation of multicellular organismal process GO:0051241 142 0.060
catabolic process GO:0009056 409 0.059
spermatogenesis GO:0007283 200 0.059
protein modification process GO:0036211 438 0.057
compound eye development GO:0048749 307 0.057
wing and notum subfield formation GO:0035309 13 0.056
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.054
regulation of organ morphogenesis GO:2000027 78 0.054
endocytosis GO:0006897 310 0.053
dendrite self avoidance GO:0070593 8 0.053
positive regulation of response to stimulus GO:0048584 323 0.053
regulation of cell morphogenesis GO:0022604 163 0.051
organic acid metabolic process GO:0006082 103 0.051
eye photoreceptor cell fate commitment GO:0042706 37 0.051
neural retina development GO:0003407 4 0.050
protein phosphorylation GO:0006468 169 0.050
blastoderm segmentation GO:0007350 159 0.050
cuticle development GO:0042335 86 0.049
positive regulation of molecular function GO:0044093 136 0.049
organelle fission GO:0048285 340 0.049
cell motility GO:0048870 251 0.049
appendage development GO:0048736 401 0.048
phagocytosis GO:0006909 215 0.048
nuclear division GO:0000280 332 0.047
homeostatic process GO:0042592 199 0.047
compound eye photoreceptor cell differentiation GO:0001751 140 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.046
establishment of proximal distal cell polarity GO:0022606 4 0.046
anterior posterior pattern specification GO:0009952 136 0.045
r3 r4 cell fate commitment GO:0007464 10 0.045
tube morphogenesis GO:0035239 191 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.045
regulation of actin cytoskeleton organization GO:0032956 42 0.045
regionalization GO:0003002 416 0.045
skin development GO:0043588 65 0.044
microtubule based movement GO:0007018 51 0.044
erbb signaling pathway GO:0038127 58 0.043
response to other organism GO:0051707 293 0.043
actin polymerization or depolymerization GO:0008154 31 0.042
negative regulation of developmental process GO:0051093 201 0.041
positive regulation of protein metabolic process GO:0051247 128 0.039
developmental growth GO:0048589 280 0.039
equator specification GO:0045317 4 0.039
regulation of neurogenesis GO:0050767 158 0.039
imaginal disc derived wing vein specification GO:0007474 48 0.038
neurological system process GO:0050877 358 0.038
sensory perception GO:0007600 196 0.038
death GO:0016265 284 0.038
rna processing GO:0006396 147 0.038
regulation of dendrite morphogenesis GO:0048814 28 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.038
regulation of cardioblast differentiation GO:0051890 9 0.037
negative regulation of cell differentiation GO:0045596 143 0.037
regulation of tube diameter open tracheal system GO:0035158 11 0.037
regulation of phosphorylation GO:0042325 147 0.036
notch signaling pathway GO:0007219 120 0.036
immune response GO:0006955 246 0.036
defense response to bacterium GO:0042742 178 0.035
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.035
retina development in camera type eye GO:0060041 4 0.035
single organism behavior GO:0044708 391 0.035
regulation of embryonic development GO:0045995 68 0.034
anterior posterior axis specification embryo GO:0008595 103 0.034
regulation of growth GO:0040008 233 0.034
response to abiotic stimulus GO:0009628 341 0.034
negative regulation of signaling GO:0023057 219 0.034
regulation of cell development GO:0060284 215 0.033
photoreceptor cell development GO:0042461 96 0.033
detection of stimulus GO:0051606 156 0.033
microtubule organizing center organization GO:0031023 168 0.033
regulation of notch signaling pathway GO:0008593 100 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.032
tissue migration GO:0090130 155 0.032
organic substance catabolic process GO:1901575 308 0.032
response to radiation GO:0009314 155 0.032
eggshell chorion assembly GO:0007306 66 0.032
regulation of localization GO:0032879 275 0.031
convergent extension GO:0060026 2 0.031
endosomal transport GO:0016197 44 0.031
r3 r4 cell differentiation GO:0048056 12 0.031
single organism intracellular transport GO:1902582 207 0.031
cellular catabolic process GO:0044248 372 0.031
regulation of response to stress GO:0080134 200 0.031
single organism biosynthetic process GO:0044711 206 0.031
establishment of localization in cell GO:0051649 402 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.030
taxis GO:0042330 304 0.030
learning or memory GO:0007611 141 0.030
mitotic spindle organization GO:0007052 220 0.030
positive regulation of signal transduction GO:0009967 223 0.030
establishment of apical basal cell polarity GO:0035089 12 0.030
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.029
regulation of phosphate metabolic process GO:0019220 210 0.029
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.029
anterior posterior axis specification GO:0009948 109 0.029
ras protein signal transduction GO:0007265 88 0.029
oxoacid metabolic process GO:0043436 103 0.028
segmentation GO:0035282 207 0.028
regulation of wound healing GO:0061041 13 0.028
regulation of wnt signaling pathway GO:0030111 68 0.028
regulation of stress activated mapk cascade GO:0032872 41 0.028
intracellular signal transduction GO:0035556 300 0.028
male gamete generation GO:0048232 201 0.027
detection of external stimulus GO:0009581 66 0.026
regulation of actin filament length GO:0030832 27 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
regulation of protein serine threonine kinase activity GO:0071900 25 0.026
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
defense response GO:0006952 300 0.026
regulation of developmental growth GO:0048638 174 0.026
cellular protein modification process GO:0006464 438 0.026
axon guidance GO:0007411 233 0.026
imaginal disc growth GO:0007446 37 0.026
axis specification GO:0009798 167 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
establishment of monopolar cell polarity GO:0061162 15 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
locomotory behavior GO:0007626 176 0.025
proteolysis GO:0006508 192 0.025
response to light stimulus GO:0009416 124 0.024
developmental growth involved in morphogenesis GO:0060560 65 0.024
epidermal growth factor receptor signaling pathway GO:0007173 58 0.024
dendrite morphogenesis GO:0048813 199 0.024
myotube cell development GO:0014904 3 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
cell cell adhesion GO:0098609 26 0.024
carboxylic acid metabolic process GO:0019752 92 0.023
rhythmic process GO:0048511 106 0.023
reproductive structure development GO:0048608 74 0.023
positive regulation of cellular protein metabolic process GO:0032270 118 0.023
cell cell junction organization GO:0045216 55 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
cell cell adhesion mediated by cadherin GO:0044331 6 0.023
larval development GO:0002164 104 0.023
eggshell formation GO:0030703 105 0.023
positive regulation of proteolysis GO:0045862 52 0.023
regulation of organ growth GO:0046620 42 0.022
neuropeptide signaling pathway GO:0007218 45 0.022
smoothened signaling pathway GO:0007224 49 0.022
immune system process GO:0002376 347 0.022
epithelial cell development GO:0002064 274 0.022
stem cell differentiation GO:0048863 117 0.022
response to organic substance GO:0010033 284 0.022
protein complex assembly GO:0006461 200 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
positive regulation of phosphorylation GO:0042327 87 0.021
eye photoreceptor cell development GO:0042462 81 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
protein complex biogenesis GO:0070271 201 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
positive regulation of mapk cascade GO:0043410 63 0.021
learning GO:0007612 75 0.021
chromosome organization GO:0051276 360 0.020
wnt signaling pathway GO:0016055 98 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
positive regulation of signaling GO:0023056 243 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
spindle organization GO:0007051 253 0.020
sister chromatid segregation GO:0000819 92 0.020
nucleus localization GO:0051647 34 0.020
dorsal appendage formation GO:0046843 47 0.019
macromolecule catabolic process GO:0009057 161 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
intracellular transport GO:0046907 228 0.018
cellular protein localization GO:0034613 160 0.018
cognition GO:0050890 141 0.018
protein catabolic process GO:0030163 101 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
establishment of nucleus localization GO:0040023 26 0.018
cardiac cell fate commitment GO:0060911 17 0.018
renal filtration cell differentiation GO:0061318 12 0.018
response to oxygen containing compound GO:1901700 200 0.018
digestive system development GO:0055123 149 0.017
regulation of imaginal disc growth GO:0045570 26 0.017
non canonical wnt signaling pathway GO:0035567 8 0.017
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.017
gene silencing GO:0016458 138 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.017
regulation of actin polymerization or depolymerization GO:0008064 27 0.017
mitotic nuclear division GO:0007067 213 0.017
chemotaxis GO:0006935 249 0.017
tripartite regional subdivision GO:0007351 103 0.017
actin filament polymerization GO:0030041 27 0.017
sex differentiation GO:0007548 81 0.016
regulation of jnk cascade GO:0046328 40 0.016
cell fate commitment involved in pattern specification GO:0060581 31 0.016
regulation of catalytic activity GO:0050790 185 0.016
branch fusion open tracheal system GO:0035147 17 0.016
regulation of cell cell adhesion GO:0022407 21 0.016
regulation of protein polymerization GO:0032271 28 0.016
protein maturation GO:0051604 71 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
innate immune response activating signal transduction GO:0002758 2 0.016
cell adhesion GO:0007155 136 0.016
developmental programmed cell death GO:0010623 138 0.015
epithelial cell type specification open tracheal system GO:0035153 11 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
detection of abiotic stimulus GO:0009582 66 0.015
response to lipopolysaccharide GO:0032496 4 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
muscle organ development GO:0007517 127 0.015
skeletal muscle fiber development GO:0048741 3 0.015
cytoplasm organization GO:0007028 64 0.015
single organism cell adhesion GO:0098602 47 0.015
response to hormone GO:0009725 45 0.015
polarized epithelial cell differentiation GO:0030859 10 0.015
gene silencing by rna GO:0031047 57 0.015
detection of visible light GO:0009584 38 0.015
positive regulation of protein kinase activity GO:0045860 25 0.015
lipid localization GO:0010876 54 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
protein ubiquitination GO:0016567 70 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
cell death GO:0008219 279 0.014
establishment of cell polarity GO:0030010 40 0.014
maintenance of location GO:0051235 73 0.014
oocyte axis specification GO:0007309 108 0.014
positive regulation of immune system process GO:0002684 68 0.014
immune effector process GO:0002252 98 0.014
regulation of mapk cascade GO:0043408 92 0.014
motor neuron axon guidance GO:0008045 58 0.014
positive regulation of catabolic process GO:0009896 105 0.014
neuron fate commitment GO:0048663 50 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.013
positive regulation of transport GO:0051050 92 0.013
compound eye photoreceptor development GO:0042051 78 0.013
cardiocyte differentiation GO:0035051 29 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
regulation of transport GO:0051049 181 0.013
apoptotic process GO:0006915 159 0.013
axonal fasciculation GO:0007413 12 0.013
chitin based cuticle development GO:0040003 49 0.013
formation of anatomical boundary GO:0048859 37 0.013
notch receptor processing GO:0007220 13 0.013
positive regulation of cell communication GO:0010647 250 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
embryonic axis specification GO:0000578 107 0.013
long term memory GO:0007616 62 0.013
monocarboxylic acid metabolic process GO:0032787 29 0.013
axis elongation GO:0003401 3 0.012
dorsal closure GO:0007391 79 0.012
chaeta development GO:0022416 97 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of nervous system development GO:0051960 248 0.012
positive regulation of cellular protein catabolic process GO:1903364 24 0.012
instar larval development GO:0002168 55 0.012
establishment of mitotic spindle localization GO:0040001 17 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
mapk cascade GO:0000165 107 0.012
convergent extension involved in gastrulation GO:0060027 2 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
negative regulation of imaginal disc growth GO:0045571 8 0.012
nephrocyte diaphragm assembly GO:0036059 3 0.012
positive regulation of developmental process GO:0051094 143 0.012
positive regulation of protein modification process GO:0031401 58 0.012
cellular macromolecule localization GO:0070727 220 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
response to bacterium GO:0009617 198 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
establishment of body hair planar orientation GO:0048105 1 0.012
regulation of cellular component size GO:0032535 98 0.011
regulation of smoothened signaling pathway GO:0008589 28 0.011
jnk cascade GO:0007254 50 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
innate immune response GO:0045087 144 0.011
muscle fiber development GO:0048747 12 0.011
regulation of cell adhesion GO:0030155 27 0.011
developmental induction GO:0031128 3 0.011
regulation of tube diameter GO:0035296 14 0.011
fertilization GO:0009566 26 0.011
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.011
cell recognition GO:0008037 102 0.011
regulation of cell death GO:0010941 173 0.011
establishment of epithelial cell polarity GO:0090162 13 0.011
macromolecular complex assembly GO:0065003 256 0.011
oocyte construction GO:0007308 112 0.011
action potential GO:0001508 13 0.011
epithelial tube formation GO:0072175 7 0.011
regulation of actin filament polymerization GO:0030833 25 0.011
ensheathment of neurons GO:0007272 10 0.011
energy taxis GO:0009453 21 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
protein processing GO:0016485 68 0.011
actin cytoskeleton organization GO:0030036 206 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.010
establishment of protein localization GO:0045184 163 0.010
programmed cell death GO:0012501 257 0.010
response to alcohol GO:0097305 95 0.010
presynaptic membrane organization GO:0097090 4 0.010
exocrine system development GO:0035272 162 0.010
neuroblast differentiation GO:0014016 29 0.010
negative regulation of cell fate commitment GO:0010454 17 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
regulation of mrna processing GO:0050684 71 0.010
regulation of molecular function GO:0065009 217 0.010
lipid modification GO:0030258 24 0.010
axon ensheathment GO:0008366 10 0.010
extracellular matrix disassembly GO:0022617 4 0.010
phototransduction GO:0007602 52 0.010

sano disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.012
disease of metabolism DOID:0014667 0 0.011
eye and adnexa disease DOID:1492 0 0.011