Drosophila melanogaster

44 known processes

nero (Dmel_CG2245)

CG2245 gene product from transcript CG2245-RA

(Aliases: Dmel\CG2245,l(3)s1921,CG2245,DOHH)

nero biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
photoreceptor cell differentiation GO:0046530 170 0.285
compound eye photoreceptor development GO:0042051 78 0.243
establishment of localization in cell GO:0051649 402 0.197
eye photoreceptor cell differentiation GO:0001754 145 0.174
protein complex assembly GO:0006461 200 0.147
vesicle mediated transport GO:0016192 381 0.133
death GO:0016265 284 0.131
endocytosis GO:0006897 310 0.119
cellular protein localization GO:0034613 160 0.113
cellular macromolecule localization GO:0070727 220 0.113
single organism intracellular transport GO:1902582 207 0.112
rhabdomere development GO:0042052 38 0.110
compound eye photoreceptor cell differentiation GO:0001751 140 0.100
photoreceptor cell development GO:0042461 96 0.099
organonitrogen compound metabolic process GO:1901564 318 0.098
eye photoreceptor cell development GO:0042462 81 0.097
cell death GO:0008219 279 0.096
negative regulation of cellular metabolic process GO:0031324 382 0.093
single organism cellular localization GO:1902580 180 0.090
organic acid metabolic process GO:0006082 103 0.086
negative regulation of rna metabolic process GO:0051253 251 0.084
protein localization GO:0008104 284 0.082
compound eye development GO:0048749 307 0.079
programmed cell death GO:0012501 257 0.079
intracellular transport GO:0046907 228 0.078
cellular macromolecular complex assembly GO:0034622 153 0.075
protein hydroxylation GO:0018126 1 0.074
intracellular protein transport GO:0006886 104 0.074
regulation of localization GO:0032879 275 0.072
regulation of autophagy GO:0010506 62 0.071
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.069
rrna processing GO:0006364 3 0.068
regulation of transport GO:0051049 181 0.068
endomembrane system organization GO:0010256 119 0.065
catabolic process GO:0009056 409 0.063
cellular catabolic process GO:0044248 372 0.062
protein complex biogenesis GO:0070271 201 0.061
protein transport GO:0015031 155 0.061
oxoacid metabolic process GO:0043436 103 0.061
membrane biogenesis GO:0044091 8 0.058
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
compound eye morphogenesis GO:0001745 249 0.055
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.055
regulation of apoptotic process GO:0042981 130 0.053
cytoplasmic transport GO:0016482 130 0.053
regulation of cellular localization GO:0060341 136 0.052
carboxylic acid metabolic process GO:0019752 92 0.052
peptidyl proline hydroxylation GO:0019511 1 0.051
regulation of cellular catabolic process GO:0031329 157 0.051
regulation of cellular amine metabolic process GO:0033238 3 0.050
organic substance transport GO:0071702 257 0.050
small molecule metabolic process GO:0044281 305 0.046
cellular amino acid metabolic process GO:0006520 61 0.046
regulation of catabolic process GO:0009894 170 0.046
golgi to plasma membrane transport GO:0006893 8 0.044
regulation of cell death GO:0010941 173 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.044
regulation of vesicle mediated transport GO:0060627 59 0.043
response to abiotic stimulus GO:0009628 341 0.042
establishment of protein localization GO:0045184 163 0.042
cellular ketone metabolic process GO:0042180 24 0.041
single organism biosynthetic process GO:0044711 206 0.040
cation transport GO:0006812 110 0.039
response to external biotic stimulus GO:0043207 293 0.039
organelle assembly GO:0070925 198 0.038
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
positive regulation of signal transduction GO:0009967 223 0.037
negative regulation of rna biosynthetic process GO:1902679 240 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
amine metabolic process GO:0009308 12 0.037
cellular response to chemical stimulus GO:0070887 199 0.037
rna processing GO:0006396 147 0.037
organonitrogen compound biosynthetic process GO:1901566 117 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
positive regulation of cell communication GO:0010647 250 0.034
protein modification process GO:0036211 438 0.034
regulation of programmed cell death GO:0043067 152 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
eye morphogenesis GO:0048592 260 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
regulation of intracellular protein transport GO:0033157 46 0.032
body morphogenesis GO:0010171 2 0.032
eye development GO:0001654 323 0.032
autophagic vacuole assembly GO:0000045 2 0.031
golgi to plasma membrane protein transport GO:0043001 8 0.031
positive regulation of signaling GO:0023056 243 0.031
response to endogenous stimulus GO:0009719 119 0.031
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.030
response to oxygen containing compound GO:1901700 200 0.030
nucleus organization GO:0006997 45 0.030
rna catabolic process GO:0006401 37 0.030
negative regulation of gene expression GO:0010629 387 0.029
negative regulation of cell death GO:0060548 81 0.029
negative regulation of biosynthetic process GO:0009890 277 0.029
positive regulation of transport GO:0051050 92 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
striated muscle cell differentiation GO:0051146 90 0.029
secretion by cell GO:0032940 101 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
cellular amine metabolic process GO:0044106 12 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
single organism membrane organization GO:0044802 93 0.028
ncrna metabolic process GO:0034660 43 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
macromolecular complex assembly GO:0065003 256 0.027
carbohydrate derivative biosynthetic process GO:1901137 85 0.027
regulation of molecular function GO:0065009 217 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
cellular component assembly involved in morphogenesis GO:0010927 151 0.026
wing disc morphogenesis GO:0007472 344 0.026
chromosome organization GO:0051276 360 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.025
nucleocytoplasmic transport GO:0006913 72 0.025
macroautophagy GO:0016236 42 0.025
ncrna processing GO:0034470 30 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
lipid modification GO:0030258 24 0.025
autophagy GO:0006914 108 0.024
regulation of cytoplasmic transport GO:1903649 47 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
sensory organ morphogenesis GO:0090596 260 0.023
regulation of protein localization GO:0032880 76 0.023
regulation of cellular response to stress GO:0080135 89 0.022
response to organic substance GO:0010033 284 0.022
response to other organism GO:0051707 293 0.022
response to extracellular stimulus GO:0009991 116 0.022
regulation of multi organism process GO:0043900 131 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
apoptotic process GO:0006915 159 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
actin filament based process GO:0030029 220 0.022
phagocytosis GO:0006909 215 0.021
locomotory behavior GO:0007626 176 0.021
cellular protein complex assembly GO:0043623 71 0.020
phosphorylation GO:0016310 294 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
response to nutrient levels GO:0031667 114 0.020
regulation of catalytic activity GO:0050790 185 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
regulation of phosphate metabolic process GO:0019220 210 0.019
macromolecule catabolic process GO:0009057 161 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
regulation of establishment of protein localization GO:0070201 61 0.019
organophosphate biosynthetic process GO:0090407 46 0.019
nuclear transport GO:0051169 72 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
centrosome organization GO:0051297 163 0.019
organic cyclic compound catabolic process GO:1901361 168 0.018
actin cytoskeleton organization GO:0030036 206 0.018
male meiosis GO:0007140 52 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of protein transport GO:0051223 57 0.018
cellular response to nutrient levels GO:0031669 62 0.018
ion transmembrane transport GO:0034220 122 0.018
protein localization to organelle GO:0033365 82 0.018
cation transmembrane transport GO:0098655 88 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
regulation of protein metabolic process GO:0051246 256 0.018
respiratory system development GO:0060541 213 0.017
chromatin organization GO:0006325 207 0.017
cellular response to heat GO:0034605 24 0.017
establishment of organelle localization GO:0051656 122 0.017
response to hypoxia GO:0001666 53 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
regulation of intracellular transport GO:0032386 64 0.017
microtubule organizing center organization GO:0031023 168 0.017
muscle structure development GO:0061061 224 0.017
response to organonitrogen compound GO:0010243 75 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
larval midgut histolysis GO:0035069 22 0.017
response to nitrogen compound GO:1901698 90 0.016
oocyte differentiation GO:0009994 145 0.016
developmental maturation GO:0021700 172 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
epithelium migration GO:0090132 148 0.016
regulation of immune system process GO:0002682 176 0.015
inorganic cation transmembrane transport GO:0098662 61 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
response to heat GO:0009408 63 0.015
lipid biosynthetic process GO:0008610 46 0.015
regulation of phosphorylation GO:0042325 147 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
response to organophosphorus GO:0046683 2 0.015
organic substance catabolic process GO:1901575 308 0.015
membrane organization GO:0061024 112 0.015
establishment of protein localization to plasma membrane GO:0090002 9 0.015
regulation of cell development GO:0060284 215 0.015
protein import into nucleus GO:0006606 51 0.015
histolysis GO:0007559 102 0.014
muscle cell differentiation GO:0042692 103 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
negative regulation of developmental process GO:0051093 201 0.014
regulation of response to external stimulus GO:0032101 115 0.014
monovalent inorganic cation transport GO:0015672 40 0.014
regulation of reproductive process GO:2000241 54 0.014
pheromone biosynthetic process GO:0042811 3 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
regulation of nucleotide metabolic process GO:0006140 62 0.014
post golgi vesicle mediated transport GO:0006892 11 0.014
localization of cell GO:0051674 257 0.014
connective tissue development GO:0061448 3 0.014
single organism behavior GO:0044708 391 0.014
open tracheal system development GO:0007424 204 0.014
proteolysis GO:0006508 192 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
peptidyl proline modification GO:0018208 3 0.014
regulation of protein catabolic process GO:0042176 55 0.013
positive regulation of protein transport GO:0051222 37 0.013
ion transport GO:0006811 145 0.013
response to organic cyclic compound GO:0014070 89 0.013
positive regulation of catabolic process GO:0009896 105 0.013
notch signaling pathway GO:0007219 120 0.013
inorganic ion transmembrane transport GO:0098660 73 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
organelle localization GO:0051640 148 0.013
protein localization to plasma membrane GO:0072659 13 0.013
mitotic spindle organization GO:0007052 220 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
regulation of cell differentiation GO:0045595 302 0.012
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
epithelial cell migration GO:0010631 148 0.012
nucleobase containing compound transport GO:0015931 56 0.012
protein localization to nucleus GO:0034504 55 0.012
regulation of cell projection organization GO:0031344 92 0.012
oxidation reduction process GO:0055114 123 0.012
protein modification by small protein removal GO:0070646 28 0.012
regulation of macroautophagy GO:0016241 15 0.012
phosphatidylinositol phosphorylation GO:0046854 10 0.012
golgi vesicle transport GO:0048193 27 0.012
regulation of protein phosphorylation GO:0001932 64 0.012
regulation of protein deacetylation GO:0090311 2 0.011
protein catabolic process GO:0030163 101 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
mrna metabolic process GO:0016071 124 0.011
nuclear pore organization GO:0006999 1 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
cellular response to starvation GO:0009267 61 0.011
smoothened signaling pathway GO:0007224 49 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of cell cycle process GO:0010564 181 0.011
spinal cord development GO:0021510 1 0.011
immune system process GO:0002376 347 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
development of primary sexual characteristics GO:0045137 50 0.011
regulation of transferase activity GO:0051338 58 0.011
mating behavior GO:0007617 106 0.011
response to starvation GO:0042594 97 0.011
positive regulation of intracellular protein transport GO:0090316 30 0.011
neurological system process GO:0050877 358 0.011
growth GO:0040007 359 0.011
regionalization GO:0003002 416 0.011
protein targeting GO:0006605 64 0.011
chorion containing eggshell formation GO:0007304 105 0.011
regulation of cell proliferation GO:0042127 163 0.011
tissue death GO:0016271 102 0.011
protein dna complex subunit organization GO:0071824 86 0.011
establishment of rna localization GO:0051236 47 0.011
protein targeting to nucleus GO:0044744 51 0.011
response to biotic stimulus GO:0009607 294 0.011
response to fungus GO:0009620 50 0.010
single organism nuclear import GO:1902593 51 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
ribonucleoprotein complex biogenesis GO:0022613 31 0.010
negative regulation of cell communication GO:0010648 223 0.010
aromatic compound catabolic process GO:0019439 166 0.010
positive regulation of gene expression GO:0010628 290 0.010
purine containing compound metabolic process GO:0072521 155 0.010
rna 3 end processing GO:0031123 45 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
organophosphate metabolic process GO:0019637 195 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
chaeta development GO:0022416 97 0.010
neuromuscular synaptic transmission GO:0007274 67 0.010
positive regulation of cell death GO:0010942 69 0.010
protein maturation GO:0051604 71 0.010
ameboidal type cell migration GO:0001667 151 0.010

nero disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
central nervous system disease DOID:331 0 0.011