Drosophila melanogaster

28 known processes

kcc (Dmel_CG5594)

kazachoc

(Aliases: Line J,Dmel\CG5594,CK01510,E(sda)J,BEST:CK01510,CG5594,l(2)60A-C,CG2768)

kcc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to mechanical stimulus GO:0009612 28 0.984
response to abiotic stimulus GO:0009628 341 0.622
single organism behavior GO:0044708 391 0.597
dendrite morphogenesis GO:0048813 199 0.575
mechanosensory behavior GO:0007638 12 0.563
ribonucleoside monophosphate catabolic process GO:0009158 39 0.282
g protein coupled receptor signaling pathway GO:0007186 136 0.260
vesicle mediated transport GO:0016192 381 0.214
synaptic transmission GO:0007268 288 0.211
regulation of multicellular organismal development GO:2000026 414 0.207
neurological system process GO:0050877 358 0.206
adult locomotory behavior GO:0008344 76 0.200
synaptic vesicle transport GO:0048489 50 0.200
regulation of cell development GO:0060284 215 0.197
cellular response to extracellular stimulus GO:0031668 64 0.196
cation transport GO:0006812 110 0.177
rhythmic excitation GO:0043179 1 0.177
locomotory behavior GO:0007626 176 0.172
cell maturation GO:0048469 144 0.168
ion transport GO:0006811 145 0.159
cation transmembrane transport GO:0098655 88 0.153
response to starvation GO:0042594 97 0.152
regulation of membrane potential GO:0042391 35 0.150
neuron neuron synaptic transmission GO:0007270 14 0.145
dendrite development GO:0016358 204 0.141
endocytosis GO:0006897 310 0.139
inorganic cation transmembrane transport GO:0098662 61 0.137
synaptic vesicle localization GO:0097479 53 0.132
developmental maturation GO:0021700 172 0.127
regulation of response to stress GO:0080134 200 0.124
establishment of synaptic vesicle localization GO:0097480 50 0.121
response to nutrient levels GO:0031667 114 0.116
positive regulation of cell communication GO:0010647 250 0.115
cell proliferation GO:0008283 299 0.113
organonitrogen compound metabolic process GO:1901564 318 0.111
adult behavior GO:0030534 137 0.105
ribonucleotide metabolic process GO:0009259 145 0.102
neuroblast proliferation GO:0007405 74 0.100
regulation of neurogenesis GO:0050767 158 0.097
synaptic vesicle recycling GO:0036465 28 0.096
phagocytosis GO:0006909 215 0.095
synaptic transmission glutamatergic GO:0035249 7 0.093
metal ion transport GO:0030001 74 0.092
positive regulation of signal transduction GO:0009967 223 0.089
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.086
regulation of anatomical structure morphogenesis GO:0022603 242 0.084
nucleoside triphosphate metabolic process GO:0009141 120 0.079
purine nucleoside monophosphate metabolic process GO:0009126 50 0.078
synaptic vesicle endocytosis GO:0048488 28 0.074
positive regulation of signaling GO:0023056 243 0.069
transmembrane transport GO:0055085 139 0.069
cellular response to external stimulus GO:0071496 66 0.069
synaptic vesicle priming GO:0016082 1 0.067
nucleoside triphosphate catabolic process GO:0009143 108 0.067
regulation of dendrite morphogenesis GO:0048814 28 0.064
dorsal ventral pattern formation GO:0009953 133 0.064
regulation of response to external stimulus GO:0032101 115 0.061
regulation of synaptic transmission glutamatergic GO:0051966 5 0.061
aromatic compound catabolic process GO:0019439 166 0.059
renal system process GO:0003014 12 0.058
microtubule based transport GO:0010970 42 0.058
neuroblast division GO:0055057 35 0.058
cellular response to nutrient levels GO:0031669 62 0.058
intracellular signal transduction GO:0035556 300 0.058
positive regulation of dendrite morphogenesis GO:0050775 9 0.057
positive regulation of response to stimulus GO:0048584 323 0.056
social behavior GO:0035176 4 0.055
signal transduction by phosphorylation GO:0023014 107 0.055
autophagic vacuole assembly GO:0000045 2 0.054
organic cyclic compound catabolic process GO:1901361 168 0.054
nucleoside monophosphate metabolic process GO:0009123 52 0.054
mating GO:0007618 120 0.053
cellular response to starvation GO:0009267 61 0.051
negative regulation of molecular function GO:0044092 51 0.051
catabolic process GO:0009056 409 0.050
cognition GO:0050890 141 0.050
mapk cascade GO:0000165 107 0.049
regulation of localization GO:0032879 275 0.049
vesicle localization GO:0051648 55 0.049
chorion containing eggshell formation GO:0007304 105 0.049
organelle fusion GO:0048284 46 0.049
cell death GO:0008219 279 0.047
nucleoside phosphate metabolic process GO:0006753 162 0.047
neuron maturation GO:0042551 31 0.047
phosphorylation GO:0016310 294 0.047
macromolecular complex assembly GO:0065003 256 0.047
intraspecies interaction between organisms GO:0051703 4 0.046
rhythmic synaptic transmission GO:0060024 2 0.046
ion transmembrane transport GO:0034220 122 0.046
negative regulation of cellular metabolic process GO:0031324 382 0.045
positive regulation of cell differentiation GO:0045597 64 0.045
negative regulation of protein metabolic process GO:0051248 85 0.045
monovalent inorganic cation transport GO:0015672 40 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.045
chromatin organization GO:0006325 207 0.044
somatic muscle development GO:0007525 66 0.044
potassium ion transport GO:0006813 20 0.043
single organism membrane organization GO:0044802 93 0.042
cellular nitrogen compound catabolic process GO:0044270 165 0.042
regulation of cellular response to stress GO:0080135 89 0.041
regulation of cellular component biogenesis GO:0044087 201 0.040
death GO:0016265 284 0.039
cellular catabolic process GO:0044248 372 0.039
spermatogenesis GO:0007283 200 0.039
establishment of vesicle localization GO:0051650 51 0.039
cellular homeostasis GO:0019725 80 0.038
nucleoside metabolic process GO:0009116 127 0.038
posttranscriptional gene silencing by rna GO:0035194 45 0.038
response to extracellular stimulus GO:0009991 116 0.037
cellular macromolecular complex assembly GO:0034622 153 0.036
outflow tract morphogenesis GO:0003151 4 0.036
axon cargo transport GO:0008088 29 0.036
telencephalon development GO:0021537 2 0.036
cellular response to dna damage stimulus GO:0006974 223 0.036
regulation of mapk cascade GO:0043408 92 0.035
response to nitrogen compound GO:1901698 90 0.035
response to hypoxia GO:0001666 53 0.035
positive regulation of developmental process GO:0051094 143 0.035
response to organic substance GO:0010033 284 0.035
purine ribonucleoside metabolic process GO:0046128 127 0.034
anatomical structure homeostasis GO:0060249 97 0.034
response to organic cyclic compound GO:0014070 89 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
atp biosynthetic process GO:0006754 2 0.034
synapse organization GO:0050808 196 0.033
signal release GO:0023061 49 0.033
regulation of protein metabolic process GO:0051246 256 0.033
ribonucleoside triphosphate metabolic process GO:0009199 119 0.033
peptide metabolic process GO:0006518 80 0.033
carboxylic acid metabolic process GO:0019752 92 0.032
protein complex biogenesis GO:0070271 201 0.032
cellular protein modification process GO:0006464 438 0.032
regulation of cell cycle GO:0051726 291 0.032
microtubule based movement GO:0007018 51 0.032
epidermis development GO:0008544 65 0.032
regulation of cell death GO:0010941 173 0.031
response to toxic substance GO:0009636 22 0.031
membrane organization GO:0061024 112 0.031
purine nucleoside triphosphate catabolic process GO:0009146 108 0.030
axis specification GO:0009798 167 0.030
protein localization GO:0008104 284 0.030
neuromuscular synaptic transmission GO:0007274 67 0.030
positive regulation of intracellular signal transduction GO:1902533 116 0.030
apoptotic process GO:0006915 159 0.030
autophagy GO:0006914 108 0.029
developmental growth GO:0048589 280 0.029
rna localization GO:0006403 115 0.029
regulation of synaptic transmission GO:0050804 69 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
ribonucleoside monophosphate metabolic process GO:0009161 51 0.029
golgi organization GO:0007030 66 0.028
cellular amide metabolic process GO:0043603 80 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
mating behavior GO:0007617 106 0.027
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.027
regulation of neuromuscular synaptic transmission GO:1900073 15 0.027
secretion by cell GO:0032940 101 0.027
positive regulation of cell development GO:0010720 61 0.027
membrane depolarization GO:0051899 4 0.027
stem cell proliferation GO:0072089 88 0.027
ribonucleotide catabolic process GO:0009261 109 0.026
regulation of ion transmembrane transport GO:0034765 27 0.026
programmed cell death GO:0012501 257 0.026
cellular protein complex assembly GO:0043623 71 0.026
regulation of apoptotic process GO:0042981 130 0.026
l glutamate import GO:0051938 1 0.026
protein modification process GO:0036211 438 0.025
protein complex assembly GO:0006461 200 0.025
mrna metabolic process GO:0016071 124 0.025
establishment of localization in cell GO:0051649 402 0.025
male gamete generation GO:0048232 201 0.025
vesicle organization GO:0016050 44 0.024
establishment of protein localization GO:0045184 163 0.024
ribonucleoside metabolic process GO:0009119 127 0.024
positive regulation of gene expression GO:0010628 290 0.024
negative regulation of programmed cell death GO:0043069 72 0.024
circadian rhythm GO:0007623 105 0.024
morphogenesis of an epithelium GO:0002009 276 0.024
negative regulation of cell cycle GO:0045786 116 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.023
response to light stimulus GO:0009416 124 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
regulation of synaptic activity GO:0060025 9 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.023
glial cell differentiation GO:0010001 35 0.023
neurotransmitter secretion GO:0007269 35 0.023
tissue morphogenesis GO:0048729 297 0.023
regulation of organelle organization GO:0033043 196 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
lipid biosynthetic process GO:0008610 46 0.022
regulation of developmental growth GO:0048638 174 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
homeostatic process GO:0042592 199 0.022
response to other organism GO:0051707 293 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.021
regulation of programmed cell death GO:0043067 152 0.021
negative regulation of cell death GO:0060548 81 0.021
growth GO:0040007 359 0.021
small molecule metabolic process GO:0044281 305 0.021
organic substance catabolic process GO:1901575 308 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
sensory perception of sound GO:0007605 56 0.021
regulation of mitotic cell cycle GO:0007346 190 0.020
secretion GO:0046903 109 0.020
gliogenesis GO:0042063 80 0.020
reproductive behavior GO:0019098 122 0.020
regulation of cell proliferation GO:0042127 163 0.020
single organism biosynthetic process GO:0044711 206 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
pole plasm assembly GO:0007315 61 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
macroautophagy GO:0016236 42 0.020
regionalization GO:0003002 416 0.019
startle response GO:0001964 16 0.019
protein phosphorylation GO:0006468 169 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.019
regulation of phosphorylation GO:0042325 147 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
lateral inhibition GO:0046331 206 0.019
sleep GO:0030431 49 0.019
regulation of response to dna damage stimulus GO:2001020 23 0.018
segmentation GO:0035282 207 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
response to organonitrogen compound GO:0010243 75 0.018
regulation of response to biotic stimulus GO:0002831 63 0.018
gravitaxis GO:0042332 26 0.018
ventral cord development GO:0007419 16 0.018
response to wounding GO:0009611 94 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
regulation of cell cycle process GO:0010564 181 0.018
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.018
regulation of map kinase activity GO:0043405 17 0.017
regulation of multi organism process GO:0043900 131 0.017
regulation of chromosome organization GO:0033044 64 0.017
aging GO:0007568 143 0.017
kidney development GO:0001822 3 0.017
head development GO:0060322 135 0.017
forebrain development GO:0030900 2 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
cellular lipid metabolic process GO:0044255 83 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
cell division GO:0051301 248 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
response to lipopolysaccharide GO:0032496 4 0.016
response to glucose GO:0009749 2 0.016
regulation of cell division GO:0051302 72 0.016
positive regulation of protein modification process GO:0031401 58 0.016
proteolysis GO:0006508 192 0.016
regulation of immune system process GO:0002682 176 0.016
positive regulation of cytoskeleton organization GO:0051495 21 0.016
organic acid metabolic process GO:0006082 103 0.016
negative regulation of gene expression GO:0010629 387 0.016
response to decreased oxygen levels GO:0036293 58 0.016
nitrogen compound transport GO:0071705 85 0.016
anion transmembrane transport GO:0098656 26 0.016
response to oxygen levels GO:0070482 59 0.016
chromatin assembly GO:0031497 48 0.016
heterocycle catabolic process GO:0046700 166 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
chromatin remodeling GO:0006338 72 0.015
cellularization GO:0007349 90 0.015
atp metabolic process GO:0046034 49 0.015
cytoplasm organization GO:0007028 64 0.015
cellular response to organic substance GO:0071310 132 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
regulation of neurotransmitter levels GO:0001505 38 0.015
nucleoside catabolic process GO:0009164 112 0.015
oocyte axis specification GO:0007309 108 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
single organism intracellular transport GO:1902582 207 0.015
regulation of transport GO:0051049 181 0.015
oxoacid metabolic process GO:0043436 103 0.015
striated muscle myosin thick filament assembly GO:0071688 3 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
chromosome organization GO:0051276 360 0.015
intracellular mrna localization GO:0008298 66 0.015
response to endogenous stimulus GO:0009719 119 0.014
regulation of catalytic activity GO:0050790 185 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
glial cell development GO:0021782 27 0.014
open tracheal system development GO:0007424 204 0.014
purine containing compound metabolic process GO:0072521 155 0.014
positive regulation of axonogenesis GO:0050772 2 0.014
negative regulation of catalytic activity GO:0043086 42 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
single organism membrane fusion GO:0044801 42 0.014
spermatid differentiation GO:0048515 114 0.014
terpenoid metabolic process GO:0006721 7 0.014
negative regulation of signal transduction GO:0009968 206 0.014
cellular response to monosaccharide stimulus GO:0071326 2 0.014
defense response GO:0006952 300 0.014
ribose phosphate metabolic process GO:0019693 145 0.013
activation of cysteine type endopeptidase activity GO:0097202 17 0.013
atp catabolic process GO:0006200 38 0.013
endomembrane system organization GO:0010256 119 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
single organism catabolic process GO:0044712 228 0.013
regulation of microtubule based process GO:0032886 49 0.013
nuclear division GO:0000280 332 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
bmp signaling pathway GO:0030509 27 0.013
sodium ion transport GO:0006814 22 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
ensheathment of neurons GO:0007272 10 0.013
nucleotide metabolic process GO:0009117 161 0.013
positive regulation of catabolic process GO:0009896 105 0.013
response to biotic stimulus GO:0009607 294 0.013
organophosphate catabolic process GO:0046434 112 0.013
positive regulation of cell motility GO:2000147 3 0.013
spinal cord development GO:0021510 1 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
positive regulation of neuromuscular synaptic transmission GO:1900075 4 0.013
central complex development GO:0048036 9 0.012
divalent inorganic cation transport GO:0072511 30 0.012
neuronal action potential GO:0019228 10 0.012
microtubule bundle formation GO:0001578 27 0.012
chromatin assembly or disassembly GO:0006333 52 0.012
macromolecule catabolic process GO:0009057 161 0.012
purine containing compound catabolic process GO:0072523 112 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
somatic stem cell division GO:0048103 37 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
memory GO:0007613 94 0.012
calcium ion homeostasis GO:0055074 23 0.012
skin development GO:0043588 65 0.012
regulation of synaptic vesicle exocytosis GO:2000300 3 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.012
cell migration GO:0016477 238 0.012
hyperosmotic response GO:0006972 1 0.012
negative regulation of signaling GO:0023057 219 0.012
sensory organ morphogenesis GO:0090596 260 0.012
positive regulation of neurotransmitter secretion GO:0001956 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
isoprenoid metabolic process GO:0006720 8 0.011
regulation of dendrite development GO:0050773 37 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
detection of chemical stimulus GO:0009593 93 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of cell shape GO:0008360 113 0.011
establishment of planar polarity GO:0001736 87 0.011
nucleobase containing compound transport GO:0015931 56 0.011
regulation of transmembrane transport GO:0034762 27 0.011
epithelial cell differentiation GO:0030855 322 0.011
regulation of protein modification process GO:0031399 112 0.011
cellular divalent inorganic cation homeostasis GO:0072503 23 0.011
neuron remodeling GO:0016322 29 0.011
regulation of hydrolase activity GO:0051336 97 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
developmental programmed cell death GO:0010623 138 0.011
regulation of cell differentiation GO:0045595 302 0.011
body morphogenesis GO:0010171 2 0.011
axon ensheathment GO:0008366 10 0.011
positive regulation of transport GO:0051050 92 0.011
regulation of cell projection organization GO:0031344 92 0.011
regulation of proteolysis GO:0030162 87 0.011
regulation of protein serine threonine kinase activity GO:0071900 25 0.011
retina development in camera type eye GO:0060041 4 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
positive regulation of response to external stimulus GO:0032103 44 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
response to radiation GO:0009314 155 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.010
protein complex disassembly GO:0043241 36 0.010
gene silencing by mirna GO:0035195 22 0.010
response to external biotic stimulus GO:0043207 293 0.010
apoptotic signaling pathway GO:0097190 27 0.010
cellular macromolecule localization GO:0070727 220 0.010
sperm individualization GO:0007291 48 0.010
action potential GO:0001508 13 0.010
cellular amine metabolic process GO:0044106 12 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
terminal button organization GO:0072553 19 0.010
epithelial cell development GO:0002064 274 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
multi organism reproductive behavior GO:0044705 121 0.010
brain morphogenesis GO:0048854 16 0.010
positive chemotaxis GO:0050918 4 0.010
regulation of heterochromatin assembly GO:0031445 8 0.010
neurotransmitter transport GO:0006836 37 0.010

kcc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.116
renal tubular transport disease DOID:447 0 0.116
bartter disease DOID:445 0 0.116
kidney disease DOID:557 0 0.116
urinary system disease DOID:18 0 0.116
diabetes mellitus DOID:9351 0 0.024
type 2 diabetes mellitus DOID:9352 0 0.024
disease of metabolism DOID:0014667 0 0.024
carbohydrate metabolism disease DOID:0050013 0 0.024
glucose metabolism disease DOID:4194 0 0.024
acquired metabolic disease DOID:0060158 0 0.024
nervous system disease DOID:863 0 0.023