Drosophila melanogaster

0 known processes

CG11221 (Dmel_CG11221)

CG11221 gene product from transcript CG11221-RA

(Aliases: Dmel\CG11221,PKN)

CG11221 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.097
organonitrogen compound metabolic process GO:1901564 318 0.074
cation transport GO:0006812 110 0.061
endocytosis GO:0006897 310 0.049
vesicle mediated transport GO:0016192 381 0.047
catabolic process GO:0009056 409 0.046
intracellular signal transduction GO:0035556 300 0.042
sensory perception of chemical stimulus GO:0007606 116 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.040
homeostatic process GO:0042592 199 0.040
regulation of phosphate metabolic process GO:0019220 210 0.039
eye development GO:0001654 323 0.039
carbohydrate derivative metabolic process GO:1901135 217 0.037
response to oxygen containing compound GO:1901700 200 0.037
negative regulation of cellular metabolic process GO:0031324 382 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
regulation of catalytic activity GO:0050790 185 0.036
single organism biosynthetic process GO:0044711 206 0.035
organophosphate metabolic process GO:0019637 195 0.035
neurological system process GO:0050877 358 0.035
response to ethanol GO:0045471 59 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
purine containing compound metabolic process GO:0072521 155 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.034
response to abiotic stimulus GO:0009628 341 0.033
macromolecular complex assembly GO:0065003 256 0.033
multi organism behavior GO:0051705 175 0.032
divalent inorganic cation homeostasis GO:0072507 29 0.032
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
actin filament based process GO:0030029 220 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
negative regulation of gene expression GO:0010629 387 0.031
cellular metal ion homeostasis GO:0006875 31 0.030
cellular catabolic process GO:0044248 372 0.030
phagocytosis GO:0006909 215 0.030
small molecule metabolic process GO:0044281 305 0.030
response to organic substance GO:0010033 284 0.030
ribonucleotide metabolic process GO:0009259 145 0.029
regulation of molecular function GO:0065009 217 0.029
metal ion homeostasis GO:0055065 44 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
regulation of nervous system development GO:0051960 248 0.028
positive regulation of biosynthetic process GO:0009891 316 0.028
chemical homeostasis GO:0048878 92 0.027
positive regulation of molecular function GO:0044093 136 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.027
actin cytoskeleton organization GO:0030036 206 0.027
cellular divalent inorganic cation homeostasis GO:0072503 23 0.027
protein heterooligomerization GO:0051291 4 0.027
detection of stimulus involved in sensory perception GO:0050906 92 0.027
cation homeostasis GO:0055080 51 0.027
regionalization GO:0003002 416 0.026
organic substance catabolic process GO:1901575 308 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.026
nucleotide metabolic process GO:0009117 161 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
transmembrane transport GO:0055085 139 0.026
compound eye development GO:0048749 307 0.026
regulation of immune system process GO:0002682 176 0.026
camera type eye development GO:0043010 4 0.026
response to alcohol GO:0097305 95 0.026
protein modification process GO:0036211 438 0.026
growth GO:0040007 359 0.025
positive regulation of signaling GO:0023056 243 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
cell proliferation GO:0008283 299 0.024
negative regulation of cell communication GO:0010648 223 0.024
negative regulation of response to stimulus GO:0048585 258 0.024
cellular ion homeostasis GO:0006873 39 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.023
protein complex assembly GO:0006461 200 0.023
negative regulation of signaling GO:0023057 219 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
cellular protein modification process GO:0006464 438 0.023
heterocycle catabolic process GO:0046700 166 0.023
neuropeptide signaling pathway GO:0007218 45 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
response to other organism GO:0051707 293 0.023
negative regulation of developmental process GO:0051093 201 0.023
cellular amine metabolic process GO:0044106 12 0.023
establishment of localization in cell GO:0051649 402 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
ion transport GO:0006811 145 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
aromatic compound catabolic process GO:0019439 166 0.022
cellular amino acid metabolic process GO:0006520 61 0.021
muscle structure development GO:0061061 224 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
cellular chemical homeostasis GO:0055082 40 0.021
amine metabolic process GO:0009308 12 0.021
positive regulation of cell communication GO:0010647 250 0.021
cell motility GO:0048870 251 0.021
protein localization GO:0008104 284 0.021
regulation of cellular component biogenesis GO:0044087 201 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.020
cellular homeostasis GO:0019725 80 0.020
lateral inhibition GO:0046331 206 0.020
regulation of organelle organization GO:0033043 196 0.020
response to organic cyclic compound GO:0014070 89 0.020
sensory perception GO:0007600 196 0.020
regulation of cellular localization GO:0060341 136 0.020
anatomical structure homeostasis GO:0060249 97 0.020
organic acid metabolic process GO:0006082 103 0.020
regulation of transport GO:0051049 181 0.020
purine nucleotide metabolic process GO:0006163 146 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
cyclic nucleotide biosynthetic process GO:0009190 25 0.019
regulation of response to stress GO:0080134 200 0.019
regulation of cell cycle GO:0051726 291 0.019
mitotic nuclear division GO:0007067 213 0.019
neuron recognition GO:0008038 101 0.019
regulation of cell proliferation GO:0042127 163 0.019
digestive tract development GO:0048565 149 0.019
tube morphogenesis GO:0035239 191 0.019
cellular cation homeostasis GO:0030003 38 0.019
response to external biotic stimulus GO:0043207 293 0.018
kidney development GO:0001822 3 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
purine containing compound biosynthetic process GO:0072522 30 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
axis specification GO:0009798 167 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
organic substance transport GO:0071702 257 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
ion homeostasis GO:0050801 55 0.018
cellular response to organic substance GO:0071310 132 0.017
response to lipopolysaccharide GO:0032496 4 0.017
forebrain development GO:0030900 2 0.017
divalent inorganic cation transport GO:0072511 30 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
regulation of anatomical structure size GO:0090066 163 0.017
single organism behavior GO:0044708 391 0.017
regulation of neurogenesis GO:0050767 158 0.017
nuclear division GO:0000280 332 0.017
embryonic axis specification GO:0000578 107 0.017
chemotaxis GO:0006935 249 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
phenol containing compound metabolic process GO:0018958 57 0.017
secretion GO:0046903 109 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
connective tissue development GO:0061448 3 0.017
defense response GO:0006952 300 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
response to radiation GO:0009314 155 0.017
response to extracellular stimulus GO:0009991 116 0.017
phosphorylation GO:0016310 294 0.016
ras protein signal transduction GO:0007265 88 0.016
positive regulation of cell motility GO:2000147 3 0.016
oxoacid metabolic process GO:0043436 103 0.016
positive regulation of signal transduction GO:0009967 223 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
organelle fission GO:0048285 340 0.016
regulation of protein metabolic process GO:0051246 256 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
negative regulation of signal transduction GO:0009968 206 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
appendage morphogenesis GO:0035107 397 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
cell migration GO:0016477 238 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
sensory perception of smell GO:0007608 80 0.016
adult behavior GO:0030534 137 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
apoptotic process GO:0006915 159 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
embryonic pattern specification GO:0009880 174 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
wing disc morphogenesis GO:0007472 344 0.015
salt aversion GO:0035199 3 0.015
developmental maturation GO:0021700 172 0.015
response to biotic stimulus GO:0009607 294 0.015
epithelial cell migration GO:0010631 148 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
regulation of multi organism process GO:0043900 131 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
positive regulation of cell migration GO:0030335 2 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.015
regulation of defense response GO:0031347 102 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
spindle organization GO:0007051 253 0.015
positive regulation of gene expression GO:0010628 290 0.015
axonogenesis GO:0007409 290 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
body morphogenesis GO:0010171 2 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of cell differentiation GO:0045595 302 0.015
tissue morphogenesis GO:0048729 297 0.015
digestive system development GO:0055123 149 0.015
feeding behavior GO:0007631 50 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
regulation of programmed cell death GO:0043067 152 0.015
response to oxidative stress GO:0006979 86 0.015
associative learning GO:0008306 65 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
dendrite morphogenesis GO:0048813 199 0.014
death GO:0016265 284 0.014
regulation of synaptic transmission GO:0050804 69 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.014
response to endogenous stimulus GO:0009719 119 0.014
regulation of growth GO:0040008 233 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
appendage development GO:0048736 401 0.014
gastrulation GO:0007369 70 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
cell death GO:0008219 279 0.014
regulation of cell development GO:0060284 215 0.014
acid secretion GO:0046717 1 0.014
actin filament organization GO:0007015 126 0.014
protein transport GO:0015031 155 0.014
endomembrane system organization GO:0010256 119 0.014
single organism catabolic process GO:0044712 228 0.014
regulation of apoptotic process GO:0042981 130 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
mapk cascade GO:0000165 107 0.014
tripartite regional subdivision GO:0007351 103 0.014
response to nitrogen compound GO:1901698 90 0.014
segmentation GO:0035282 207 0.014
regulation of catabolic process GO:0009894 170 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of mapk cascade GO:0043408 92 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
metal ion transport GO:0030001 74 0.013
positive regulation of immune system process GO:0002684 68 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
anion homeostasis GO:0055081 3 0.013
regulation of cell death GO:0010941 173 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
single organism cellular localization GO:1902580 180 0.013
regulation of neuron differentiation GO:0045664 103 0.013
cation transmembrane transport GO:0098655 88 0.013
positive regulation of nucleotide metabolic process GO:0045981 55 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
rna processing GO:0006396 147 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
regulation of response to external stimulus GO:0032101 115 0.013
cellular calcium ion homeostasis GO:0006874 21 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
response to monosaccharide GO:0034284 4 0.013
muscle organ development GO:0007517 127 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
response to lipid GO:0033993 38 0.013
response to alkaloid GO:0043279 26 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
store operated calcium entry GO:0002115 3 0.013
sensory perception of pain GO:0019233 4 0.013
nucleoside catabolic process GO:0009164 112 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
anterior posterior axis specification GO:0009948 109 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
chromosome organization GO:0051276 360 0.013
retina development in camera type eye GO:0060041 4 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
epithelial cell differentiation GO:0030855 322 0.013
dna metabolic process GO:0006259 227 0.012
cell division GO:0051301 248 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
digestive tract morphogenesis GO:0048546 127 0.012
programmed cell death GO:0012501 257 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
cytosolic calcium ion homeostasis GO:0051480 11 0.012
ameboidal type cell migration GO:0001667 151 0.012
protein complex biogenesis GO:0070271 201 0.012
dendrite development GO:0016358 204 0.012
nephron development GO:0072006 3 0.012
positive regulation of catabolic process GO:0009896 105 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
single organism intracellular transport GO:1902582 207 0.012
cellular ketone metabolic process GO:0042180 24 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of localization GO:0032879 275 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
regulation of membrane potential GO:0042391 35 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
cyclic purine nucleotide metabolic process GO:0052652 25 0.012
cellular macromolecule localization GO:0070727 220 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
synapse organization GO:0050808 196 0.012
regulation of immune response GO:0050776 118 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
embryonic morphogenesis GO:0048598 206 0.012
secretion by cell GO:0032940 101 0.012
positive regulation of cellular component organization GO:0051130 156 0.011
central nervous system development GO:0007417 201 0.011
rna localization GO:0006403 115 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
mitotic spindle organization GO:0007052 220 0.011
epithelium migration GO:0090132 148 0.011
hindbrain development GO:0030902 2 0.011
anterior posterior pattern specification GO:0009952 136 0.011
monocarboxylic acid transport GO:0015718 3 0.011
negative regulation of insulin secretion GO:0046676 1 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
response to bacterium GO:0009617 198 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
axon development GO:0061564 297 0.011
regulation of developmental growth GO:0048638 174 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
developmental growth GO:0048589 280 0.011
establishment of protein localization GO:0045184 163 0.011
calcium ion homeostasis GO:0055074 23 0.011
spermatogenesis GO:0007283 200 0.011
tissue migration GO:0090130 155 0.011
proteolysis GO:0006508 192 0.011
stem cell proliferation GO:0072089 88 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
neuromuscular synaptic transmission GO:0007274 67 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
aggressive behavior GO:0002118 63 0.011
hindgut morphogenesis GO:0007442 58 0.011
immune response activating signal transduction GO:0002757 2 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
ion transmembrane transport GO:0034220 122 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
response to organophosphorus GO:0046683 2 0.011
stem cell differentiation GO:0048863 117 0.011
multi multicellular organism process GO:0044706 123 0.011
response to ketone GO:1901654 34 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
response to organonitrogen compound GO:0010243 75 0.011
cognition GO:0050890 141 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
positive regulation of immune response GO:0050778 63 0.011
sensory organ morphogenesis GO:0090596 260 0.011
response to light stimulus GO:0009416 124 0.011
positive regulation of cell death GO:0010942 69 0.011
steroid catabolic process GO:0006706 1 0.011
oocyte axis specification GO:0007309 108 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
purine containing compound catabolic process GO:0072523 112 0.010
telencephalon development GO:0021537 2 0.010
regulation of innate immune response GO:0045088 71 0.010
taxis GO:0042330 304 0.010
ribose phosphate biosynthetic process GO:0046390 28 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
nucleoside metabolic process GO:0009116 127 0.010
ribonucleotide biosynthetic process GO:0009260 28 0.010
protein phosphorylation GO:0006468 169 0.010
multi organism reproductive behavior GO:0044705 121 0.010
imaginal disc pattern formation GO:0007447 91 0.010
vitamin biosynthetic process GO:0009110 1 0.010
regulation of phosphorylation GO:0042325 147 0.010
immune effector process GO:0002252 98 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
nucleotide biosynthetic process GO:0009165 34 0.010
eye morphogenesis GO:0048592 260 0.010
response to temperature stimulus GO:0009266 106 0.010
locomotory behavior GO:0007626 176 0.010

CG11221 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
cardiovascular system disease DOID:1287 0 0.019
musculoskeletal system disease DOID:17 0 0.018
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
connective tissue disease DOID:65 0 0.011