Drosophila melanogaster

82 known processes

smg (Dmel_CG5263)

smaug

(Aliases: CG5263,Smg,anonD69,D69,anon-D69,SMG,Dmel\CG5263)

smg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle localization GO:0051640 148 0.246
organelle fission GO:0048285 340 0.135
cellular catabolic process GO:0044248 372 0.126
imaginal disc derived wing morphogenesis GO:0007476 337 0.124
cellularization GO:0007349 90 0.120
single organism intracellular transport GO:1902582 207 0.113
embryonic development via the syncytial blastoderm GO:0001700 148 0.108
regulation of synapse organization GO:0050807 110 0.104
regulation of protein metabolic process GO:0051246 256 0.096
taxis GO:0042330 304 0.096
imaginal disc derived appendage development GO:0048737 399 0.089
developmental growth GO:0048589 280 0.083
pole cell development GO:0007277 26 0.081
intracellular transport GO:0046907 228 0.074
cell cycle phase transition GO:0044770 140 0.072
positive regulation of macromolecule metabolic process GO:0010604 405 0.070
establishment of localization in cell GO:0051649 402 0.069
establishment of protein localization GO:0045184 163 0.068
nuclear division GO:0000280 332 0.068
positive regulation of cellular component organization GO:0051130 156 0.068
wing disc morphogenesis GO:0007472 344 0.067
meiotic cell cycle GO:0051321 171 0.065
establishment of organelle localization GO:0051656 122 0.064
nucleoside triphosphate metabolic process GO:0009141 120 0.064
catabolic process GO:0009056 409 0.063
female meiotic division GO:0007143 70 0.060
dna conformation change GO:0071103 105 0.058
purine containing compound metabolic process GO:0072521 155 0.057
embryo development ending in birth or egg hatching GO:0009792 152 0.056
regulation of catabolic process GO:0009894 170 0.053
protein transport GO:0015031 155 0.053
organic substance transport GO:0071702 257 0.051
ras protein signal transduction GO:0007265 88 0.049
dna metabolic process GO:0006259 227 0.048
glycosyl compound metabolic process GO:1901657 127 0.048
cellular response to dna damage stimulus GO:0006974 223 0.048
synapse assembly GO:0007416 143 0.047
small gtpase mediated signal transduction GO:0007264 88 0.046
regulation of developmental growth GO:0048638 174 0.046
response to radiation GO:0009314 155 0.045
sensory organ morphogenesis GO:0090596 260 0.044
aging GO:0007568 143 0.044
macromolecule catabolic process GO:0009057 161 0.044
vesicle mediated transport GO:0016192 381 0.044
response to extracellular stimulus GO:0009991 116 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
regulation of cell cycle GO:0051726 291 0.042
purine nucleoside triphosphate metabolic process GO:0009144 119 0.042
ribonucleoside catabolic process GO:0042454 112 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
organophosphate catabolic process GO:0046434 112 0.042
regulation of multicellular organismal development GO:2000026 414 0.041
purine containing compound catabolic process GO:0072523 112 0.041
chromosome segregation GO:0007059 157 0.041
purine ribonucleoside metabolic process GO:0046128 127 0.041
appendage morphogenesis GO:0035107 397 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
oocyte differentiation GO:0009994 145 0.039
localization of cell GO:0051674 257 0.039
multicellular organismal aging GO:0010259 140 0.039
nuclear migration GO:0007097 20 0.038
regulation of cellular catabolic process GO:0031329 157 0.038
positive regulation of cellular catabolic process GO:0031331 95 0.038
ribonucleoside metabolic process GO:0009119 127 0.037
single organism cellular localization GO:1902580 180 0.037
endocytosis GO:0006897 310 0.036
positive regulation of molecular function GO:0044093 136 0.036
regulation of organelle organization GO:0033043 196 0.036
synaptic growth at neuromuscular junction GO:0051124 119 0.036
determination of adult lifespan GO:0008340 137 0.035
purine ribonucleoside catabolic process GO:0046130 112 0.035
meiotic nuclear division GO:0007126 151 0.035
neutral lipid biosynthetic process GO:0046460 2 0.035
growth GO:0040007 359 0.034
response to organic substance GO:0010033 284 0.034
protein modification process GO:0036211 438 0.034
pole cell formation GO:0007279 19 0.034
regulation of synapse structure and activity GO:0050803 128 0.034
negative regulation of gene expression GO:0010629 387 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.032
multi multicellular organism process GO:0044706 123 0.032
ameboidal type cell migration GO:0001667 151 0.032
chromosome separation GO:0051304 42 0.031
endomembrane system organization GO:0010256 119 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
aromatic compound catabolic process GO:0019439 166 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
cell division GO:0051301 248 0.030
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.030
response to abiotic stimulus GO:0009628 341 0.030
oocyte axis specification GO:0007309 108 0.029
gene silencing by rna GO:0031047 57 0.029
proteolysis GO:0006508 192 0.029
nucleotide metabolic process GO:0009117 161 0.029
rho protein signal transduction GO:0007266 14 0.029
cellular macromolecule catabolic process GO:0044265 136 0.028
organic substance catabolic process GO:1901575 308 0.028
body morphogenesis GO:0010171 2 0.028
regulation of cellular component biogenesis GO:0044087 201 0.028
intracellular protein transport GO:0006886 104 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
cellular protein modification process GO:0006464 438 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
oocyte construction GO:0007308 112 0.028
nucleoside catabolic process GO:0009164 112 0.028
tissue migration GO:0090130 155 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
cellular macromolecule localization GO:0070727 220 0.027
organophosphate metabolic process GO:0019637 195 0.027
actin filament based process GO:0030029 220 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
regulation of molecular function GO:0065009 217 0.027
meiotic chromosome segregation GO:0045132 59 0.026
regulation of transport GO:0051049 181 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
border follicle cell migration GO:0007298 113 0.026
immune system process GO:0002376 347 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
cytoplasmic transport GO:0016482 130 0.026
pole plasm rna localization GO:0007316 52 0.026
positive regulation of protein metabolic process GO:0051247 128 0.026
chromosome organization GO:0051276 360 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
regulation of synapse assembly GO:0051963 94 0.025
nucleotide catabolic process GO:0009166 109 0.025
mitotic nuclear division GO:0007067 213 0.025
centrosome duplication GO:0051298 121 0.025
female meiosis chromosome segregation GO:0016321 33 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
nucleoside triphosphate catabolic process GO:0009143 108 0.025
nucleoside metabolic process GO:0009116 127 0.024
small molecule metabolic process GO:0044281 305 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
chemotaxis GO:0006935 249 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
regulation of cell differentiation GO:0045595 302 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
regulation of growth GO:0040008 233 0.023
positive regulation of catabolic process GO:0009896 105 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
nuclear import GO:0051170 51 0.022
guanosine containing compound catabolic process GO:1901069 74 0.022
positive regulation of nucleotide catabolic process GO:0030813 46 0.022
chromatin remodeling GO:0006338 72 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
dna packaging GO:0006323 91 0.022
response to endogenous stimulus GO:0009719 119 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
regulation of response to stress GO:0080134 200 0.022
sister chromatid segregation GO:0000819 92 0.022
positive regulation of gtpase activity GO:0043547 43 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
regulation of localization GO:0032879 275 0.021
protein secretion GO:0009306 45 0.021
protein complex biogenesis GO:0070271 201 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
phosphorylation GO:0016310 294 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
regulation of protein localization GO:0032880 76 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
regulation of catalytic activity GO:0050790 185 0.020
response to starvation GO:0042594 97 0.020
regulation of embryonic development GO:0045995 68 0.020
gtp catabolic process GO:0006184 72 0.020
actin cytoskeleton organization GO:0030036 206 0.020
response to oxygen containing compound GO:1901700 200 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
neuromuscular junction development GO:0007528 149 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
heterocycle catabolic process GO:0046700 166 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
homeostatic process GO:0042592 199 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
response to nutrient levels GO:0031667 114 0.019
rna localization GO:0006403 115 0.019
germ line stem cell division GO:0042078 25 0.018
photoreceptor cell development GO:0042461 96 0.018
cell migration GO:0016477 238 0.018
regulation of nucleotide metabolic process GO:0006140 62 0.018
dorsal ventral axis specification GO:0009950 66 0.018
macromolecular complex assembly GO:0065003 256 0.018
protein targeting GO:0006605 64 0.018
actin filament organization GO:0007015 126 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
oocyte development GO:0048599 124 0.018
negative regulation of signaling GO:0023057 219 0.018
regulation of establishment of protein localization GO:0070201 61 0.017
cell proliferation GO:0008283 299 0.017
protein catabolic process GO:0030163 101 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
epithelial cell differentiation GO:0030855 322 0.017
cognition GO:0050890 141 0.017
positive regulation of proteolysis GO:0045862 52 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
response to organonitrogen compound GO:0010243 75 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
protein localization to organelle GO:0033365 82 0.017
locomotory behavior GO:0007626 176 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
cellular protein localization GO:0034613 160 0.016
spermatogenesis GO:0007283 200 0.016
anatomical structure homeostasis GO:0060249 97 0.016
cytokinesis GO:0000910 90 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
gtp metabolic process GO:0046039 72 0.016
cytoplasm organization GO:0007028 64 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
protein localization GO:0008104 284 0.015
gene silencing GO:0016458 138 0.015
embryonic axis specification GO:0000578 107 0.015
acylglycerol biosynthetic process GO:0046463 2 0.015
cell motility GO:0048870 251 0.015
regulation of proteolysis GO:0030162 87 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
regulation of cellular localization GO:0060341 136 0.014
response to lipopolysaccharide GO:0032496 4 0.014
response to light stimulus GO:0009416 124 0.014
positive regulation of gene expression GO:0010628 290 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
meiotic cell cycle process GO:1903046 132 0.014
response to biotic stimulus GO:0009607 294 0.014
eye development GO:0001654 323 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
meiosis i GO:0007127 59 0.014
nuclear transcribed mrna catabolic process GO:0000956 24 0.014
compound eye morphogenesis GO:0001745 249 0.014
positive regulation of developmental growth GO:0048639 62 0.014
protein complex assembly GO:0006461 200 0.014
regulation of hydrolase activity GO:0051336 97 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of gtpase activity GO:0043087 44 0.014
response to bacterium GO:0009617 198 0.014
spindle organization GO:0007051 253 0.014
cellular homeostasis GO:0019725 80 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
lipid homeostasis GO:0055088 33 0.013
response to nitrogen compound GO:1901698 90 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
pole plasm assembly GO:0007315 61 0.013
non sensory hair organization GO:0035316 47 0.013
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.013
microtubule organizing center organization GO:0031023 168 0.013
positive regulation of cell cycle GO:0045787 43 0.013
chromatin organization GO:0006325 207 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
compound eye development GO:0048749 307 0.013
defense response to other organism GO:0098542 225 0.013
protein import GO:0017038 55 0.013
cellular amino acid metabolic process GO:0006520 61 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
regulation of translation GO:0006417 56 0.012
regulation of reproductive process GO:2000241 54 0.012
larval development GO:0002164 104 0.012
establishment of nucleus localization GO:0040023 26 0.012
cellular response to organic substance GO:0071310 132 0.012
intracellular signal transduction GO:0035556 300 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of gtp catabolic process GO:0033124 44 0.012
oxoacid metabolic process GO:0043436 103 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
translation GO:0006412 69 0.012
kidney development GO:0001822 3 0.012
ovarian follicle cell development GO:0030707 248 0.012
regulation of protein transport GO:0051223 57 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
reproductive structure development GO:0048608 74 0.011
imaginal disc derived wing hair organization GO:0035317 45 0.011
multicellular organism growth GO:0035264 46 0.011
developmental maturation GO:0021700 172 0.011
positive regulation of cell communication GO:0010647 250 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
appendage development GO:0048736 401 0.011
regulation of endocytosis GO:0030100 37 0.011
cell death GO:0008219 279 0.011
ion transmembrane transport GO:0034220 122 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
male meiosis GO:0007140 52 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of oocyte development GO:0060281 27 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of cell division GO:0051302 72 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
single organism biosynthetic process GO:0044711 206 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of phosphorylation GO:0042325 147 0.011
response to other organism GO:0051707 293 0.011
negative regulation of cytoskeleton organization GO:0051494 30 0.011
chitin based cuticle development GO:0040003 49 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
gastrulation GO:0007369 70 0.011
axis specification GO:0009798 167 0.010
regulation of secretion by cell GO:1903530 39 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
negative regulation of developmental process GO:0051093 201 0.010
positive regulation of nucleoside metabolic process GO:0045979 47 0.010
establishment of rna localization GO:0051236 47 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
chromosome condensation GO:0030261 41 0.010
regulation of rho gtpase activity GO:0032319 20 0.010
sperm competition GO:0046692 21 0.010
positive regulation of protein catabolic process GO:0045732 34 0.010
synaptic transmission GO:0007268 288 0.010
mitotic g2 dna damage checkpoint GO:0007095 69 0.010
regulation of protein catabolic process GO:0042176 55 0.010

smg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011