Drosophila melanogaster

89 known processes

Gad1 (Dmel_CG14994)

Glutamic acid decarboxylase 1

(Aliases: Gad,CG14994,GAD,l(3)SH10,Glb,gad1,dGad1,GAD[[1]],DGad1,dgad1,Dmel\CG14994,l(3)64An,DGAD1,gad,GAD-1,GAD1)

Gad1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.844
adult locomotory behavior GO:0008344 76 0.715
synaptic transmission GO:0007268 288 0.673
courtship behavior GO:0007619 68 0.597
single organism membrane fusion GO:0044801 42 0.560
adult behavior GO:0030534 137 0.486
regulation of synaptic transmission GO:0050804 69 0.444
locomotory behavior GO:0007626 176 0.393
regulation of synapse organization GO:0050807 110 0.361
organelle fusion GO:0048284 46 0.352
response to ethanol GO:0045471 59 0.335
vesicle fusion GO:0006906 19 0.320
larval behavior GO:0030537 42 0.243
flight behavior GO:0007629 26 0.231
neuromuscular synaptic transmission GO:0007274 67 0.231
nucleoside catabolic process GO:0009164 112 0.230
multi organism reproductive behavior GO:0044705 121 0.226
heterocycle catabolic process GO:0046700 166 0.209
male mating behavior GO:0060179 70 0.209
synaptic vesicle recycling GO:0036465 28 0.205
positive regulation of signaling GO:0023056 243 0.205
sensory perception GO:0007600 196 0.203
regulation of localization GO:0032879 275 0.202
regulation of neurotransmitter levels GO:0001505 38 0.202
Zebrafish
nucleobase containing compound catabolic process GO:0034655 165 0.199
aromatic compound catabolic process GO:0019439 166 0.189
regulation of synapse structure and activity GO:0050803 128 0.187
neurotransmitter secretion GO:0007269 35 0.183
ion transmembrane transport GO:0034220 122 0.179
actin cytoskeleton organization GO:0030036 206 0.166
ribonucleoside triphosphate metabolic process GO:0009199 119 0.165
male courtship behavior veined wing generated song production GO:0045433 20 0.165
mating GO:0007618 120 0.164
regulation of synapse assembly GO:0051963 94 0.156
multi multicellular organism process GO:0044706 123 0.141
ion transport GO:0006811 145 0.140
organelle localization GO:0051640 148 0.139
negative regulation of response to stimulus GO:0048585 258 0.129
multi organism behavior GO:0051705 175 0.127
organonitrogen compound metabolic process GO:1901564 318 0.127
regulation of nucleoside metabolic process GO:0009118 50 0.124
transmembrane transport GO:0055085 139 0.122
male courtship behavior veined wing vibration GO:0016545 21 0.122
neurological system process GO:0050877 358 0.121
gtp catabolic process GO:0006184 72 0.119
male courtship behavior GO:0008049 63 0.119
actin filament based process GO:0030029 220 0.117
small molecule metabolic process GO:0044281 305 0.115
larval locomotory behavior GO:0008345 27 0.113
membrane fusion GO:0061025 42 0.111
positive regulation of cell communication GO:0010647 250 0.111
intraspecies interaction between organisms GO:0051703 4 0.104
positive regulation of response to stimulus GO:0048584 323 0.102
purine ribonucleotide catabolic process GO:0009154 109 0.102
catabolic process GO:0009056 409 0.101
reproductive behavior GO:0019098 122 0.094
vesicle organization GO:0016050 44 0.091
cognition GO:0050890 141 0.089
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.088
establishment of vesicle localization GO:0051650 51 0.088
organophosphate catabolic process GO:0046434 112 0.086
regulation of neuronal synaptic plasticity GO:0048168 8 0.084
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.084
mating behavior GO:0007617 106 0.082
single organism catabolic process GO:0044712 228 0.082
olfactory behavior GO:0042048 97 0.082
response to alcohol GO:0097305 95 0.082
regulation of cellular component biogenesis GO:0044087 201 0.079
organophosphate metabolic process GO:0019637 195 0.078
synaptic vesicle endocytosis GO:0048488 28 0.078
synapse organization GO:0050808 196 0.072
cell death GO:0008219 279 0.071
neurotransmitter transport GO:0006836 37 0.069
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.068
regulation of neurotransmitter secretion GO:0046928 14 0.068
oocyte differentiation GO:0009994 145 0.068
nucleotide catabolic process GO:0009166 109 0.068
vesicle mediated transport GO:0016192 381 0.068
intracellular signal transduction GO:0035556 300 0.068
learning or memory GO:0007611 141 0.067
establishment of localization in cell GO:0051649 402 0.066
regulation of ion transport GO:0043269 39 0.066
purine nucleotide catabolic process GO:0006195 109 0.066
synaptic vesicle transport GO:0048489 50 0.065
macromolecular complex assembly GO:0065003 256 0.064
dendrite morphogenesis GO:0048813 199 0.063
cellular nitrogen compound catabolic process GO:0044270 165 0.062
regulation of cell death GO:0010941 173 0.061
programmed cell death GO:0012501 257 0.061
response to light stimulus GO:0009416 124 0.061
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.061
regulation of organelle organization GO:0033043 196 0.059
regulation of transport GO:0051049 181 0.059
serotonin uptake GO:0051610 1 0.057
regulation of transmembrane transport GO:0034762 27 0.057
single organism membrane organization GO:0044802 93 0.057
larval development GO:0002164 104 0.057
ribonucleotide catabolic process GO:0009261 109 0.056
purine containing compound catabolic process GO:0072523 112 0.055
organonitrogen compound catabolic process GO:1901565 128 0.054
sensory perception of mechanical stimulus GO:0050954 72 0.053
cell motility GO:0048870 251 0.053
sensory perception of chemical stimulus GO:0007606 116 0.053
ribonucleoside catabolic process GO:0042454 112 0.052
negative regulation of synapse assembly GO:0051964 39 0.052
positive regulation of nucleotide catabolic process GO:0030813 46 0.052
regulation of catabolic process GO:0009894 170 0.052
endocytosis GO:0006897 310 0.050
glycosyl compound catabolic process GO:1901658 112 0.050
organelle assembly GO:0070925 198 0.049
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.049
death GO:0016265 284 0.049
regulation of multicellular organismal development GO:2000026 414 0.048
amine metabolic process GO:0009308 12 0.048
positive regulation of synaptic transmission GO:0050806 15 0.048
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
carbohydrate derivative catabolic process GO:1901136 118 0.047
metal ion homeostasis GO:0055065 44 0.047
nucleoside triphosphate metabolic process GO:0009141 120 0.046
regulation of vesicle mediated transport GO:0060627 59 0.046
establishment of synaptic vesicle localization GO:0097480 50 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.045
regulation of synaptic transmission glutamatergic GO:0051966 5 0.044
cellular ion homeostasis GO:0006873 39 0.044
cell cell signaling involved in cell fate commitment GO:0045168 210 0.044
regulation of epithelial cell proliferation GO:0050678 4 0.043
protein complex assembly GO:0006461 200 0.042
response to radiation GO:0009314 155 0.042
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.042
purine nucleoside catabolic process GO:0006152 112 0.041
regulation of locomotion GO:0040012 42 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
regulation of cell differentiation GO:0045595 302 0.041
organic substance catabolic process GO:1901575 308 0.041
ribonucleoside metabolic process GO:0009119 127 0.040
nucleoside phosphate catabolic process GO:1901292 110 0.040
regulation of behavior GO:0050795 75 0.039
pole plasm oskar mrna localization GO:0045451 46 0.039
organic cyclic compound catabolic process GO:1901361 168 0.038
signal release GO:0023061 49 0.038
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.037
regulation of synaptic plasticity GO:0048167 14 0.037
cation transmembrane transport GO:0098655 88 0.037
response to mechanical stimulus GO:0009612 28 0.036
protein modification process GO:0036211 438 0.035
purine nucleoside triphosphate metabolic process GO:0009144 119 0.035
cellular metal ion homeostasis GO:0006875 31 0.035
purine nucleoside triphosphate catabolic process GO:0009146 108 0.034
cytoplasmic transport GO:0016482 130 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
purine nucleoside metabolic process GO:0042278 127 0.033
positive regulation of signal transduction GO:0009967 223 0.033
pole plasm mrna localization GO:0019094 49 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.031
dna conformation change GO:0071103 105 0.031
glycosyl compound metabolic process GO:1901657 127 0.031
vesicle localization GO:0051648 55 0.031
cation transport GO:0006812 110 0.031
behavioral response to ethanol GO:0048149 49 0.030
regulation of protein metabolic process GO:0051246 256 0.030
cellular catabolic process GO:0044248 372 0.030
nucleoside metabolic process GO:0009116 127 0.030
sensory perception of smell GO:0007608 80 0.030
rhythmic synaptic transmission GO:0060024 2 0.030
positive regulation of molecular function GO:0044093 136 0.029
sensory perception of sound GO:0007605 56 0.029
regulation of neuromuscular synaptic transmission GO:1900073 15 0.029
regulation of programmed cell death GO:0043067 152 0.029
nucleoside triphosphate catabolic process GO:0009143 108 0.029
neuron neuron synaptic transmission GO:0007270 14 0.029
Worm
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.029
regulation of necrotic cell death GO:0010939 1 0.029
positive regulation of transport GO:0051050 92 0.029
cellular chemical homeostasis GO:0055082 40 0.028
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.028
cellular calcium ion homeostasis GO:0006874 21 0.028
protein complex biogenesis GO:0070271 201 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
respiratory system development GO:0060541 213 0.027
chemosensory behavior GO:0007635 106 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
gtp metabolic process GO:0046039 72 0.027
regulation of cellular localization GO:0060341 136 0.026
muscle contraction GO:0006936 13 0.026
positive regulation of intracellular signal transduction GO:1902533 116 0.026
regulation of transmembrane transporter activity GO:0022898 6 0.026
regulation of secretion by cell GO:1903530 39 0.026
body morphogenesis GO:0010171 2 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
response to temperature stimulus GO:0009266 106 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.025
synapse assembly GO:0007416 143 0.025
positive regulation of hydrolase activity GO:0051345 78 0.025
eye antennal disc development GO:0035214 60 0.025
chemical homeostasis GO:0048878 92 0.025
cellular amide metabolic process GO:0043603 80 0.025
regulation of catalytic activity GO:0050790 185 0.025
striated muscle contraction GO:0006941 5 0.025
actin filament based movement GO:0030048 26 0.024
social behavior GO:0035176 4 0.024
positive regulation of phosphate metabolic process GO:0045937 139 0.024
synaptic growth at neuromuscular junction GO:0051124 119 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
positive regulation of cellular component biogenesis GO:0044089 80 0.024
purine containing compound metabolic process GO:0072521 155 0.024
regulation of purine nucleotide catabolic process GO:0033121 48 0.024
organic acid metabolic process GO:0006082 103 0.023
response to oxygen containing compound GO:1901700 200 0.023
circadian sleep wake cycle sleep GO:0050802 23 0.022
membrane organization GO:0061024 112 0.022
response to food GO:0032094 3 0.022
pole plasm rna localization GO:0007316 52 0.022
positive regulation of synaptic vesicle recycling GO:1903423 4 0.022
lipid modification GO:0030258 24 0.022
regulation of multi organism process GO:0043900 131 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
brain development GO:0007420 120 0.021
establishment of organelle localization GO:0051656 122 0.021
guanosine containing compound catabolic process GO:1901069 74 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
regulation of hydrolase activity GO:0051336 97 0.020
rhythmic behavior GO:0007622 76 0.020
cell migration GO:0016477 238 0.020
organic hydroxy compound metabolic process GO:1901615 83 0.020
neuromuscular junction development GO:0007528 149 0.020
cellular amine metabolic process GO:0044106 12 0.020
maternal determination of anterior posterior axis embryo GO:0008358 74 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
actomyosin structure organization GO:0031032 56 0.019
cellular macromolecule localization GO:0070727 220 0.019
glycerophospholipid metabolic process GO:0006650 23 0.019
positive regulation of catabolic process GO:0009896 105 0.019
synaptic vesicle localization GO:0097479 53 0.018
ameboidal type cell migration GO:0001667 151 0.018
rhythmic excitation GO:0043179 1 0.018
developmental maturation GO:0021700 172 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
retina development in camera type eye GO:0060041 4 0.018
regulation of ion transmembrane transport GO:0034765 27 0.018
musculoskeletal movement GO:0050881 3 0.018
regulation of cell maturation GO:1903429 27 0.018
eye photoreceptor cell development GO:0042462 81 0.018
regulation of embryonic pattern specification GO:1902875 27 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.018
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
phagocytosis GO:0006909 215 0.017
regulation of adenylate cyclase activity GO:0045761 12 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
organic substance transport GO:0071702 257 0.017
positive regulation of ras gtpase activity GO:0032320 36 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
regulation of cellular component movement GO:0051270 42 0.017
negative regulation of protein metabolic process GO:0051248 85 0.016
regulation of terminal button organization GO:2000331 11 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
apoptotic process GO:0006915 159 0.016
response to pain GO:0048265 3 0.016
immune system process GO:0002376 347 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.016
response to osmotic stress GO:0006970 14 0.015
cellular cation homeostasis GO:0030003 38 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
protein transport GO:0015031 155 0.015
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
circadian behavior GO:0048512 76 0.015
mitotic chromosome condensation GO:0007076 22 0.015
notch signaling pathway GO:0007219 120 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of ion transmembrane transporter activity GO:0032412 6 0.015
transmission of nerve impulse GO:0019226 12 0.014
endomembrane system organization GO:0010256 119 0.014
regulation of response to external stimulus GO:0032101 115 0.014
growth GO:0040007 359 0.014
male courtship behavior veined wing extension GO:0048065 22 0.014
sensory perception of pain GO:0019233 4 0.014
ras protein signal transduction GO:0007265 88 0.014
necrotic cell death GO:0070265 1 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
regulation of glutamate receptor signaling pathway GO:1900449 1 0.014
neuromuscular process GO:0050905 21 0.014
terminal button organization GO:0072553 19 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.013
cellular lipid metabolic process GO:0044255 83 0.013
nitrogen compound transport GO:0071705 85 0.013
positive regulation of exocytosis GO:0045921 4 0.013
response to hypoxia GO:0001666 53 0.013
maintenance of location GO:0051235 73 0.013
synaptic vesicle exocytosis GO:0016079 16 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of apoptotic process GO:0042981 130 0.013
cell junction assembly GO:0034329 42 0.013
intracellular transport GO:0046907 228 0.013
neurotransmitter uptake GO:0001504 1 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
response to heat GO:0009408 63 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
response to abiotic stimulus GO:0009628 341 0.013
epithelium migration GO:0090132 148 0.012
regulation of protein modification process GO:0031399 112 0.012
divalent inorganic cation homeostasis GO:0072507 29 0.012
positive regulation of neurotransmitter secretion GO:0001956 2 0.012
membrane depolarization GO:0051899 4 0.012
anesthesia resistant memory GO:0007615 6 0.012
cellular homeostasis GO:0019725 80 0.012
heart process GO:0003015 37 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
cell junction organization GO:0034330 57 0.012
secretion GO:0046903 109 0.012
negative regulation of developmental process GO:0051093 201 0.012
protein catabolic process GO:0030163 101 0.012
regulation of protein localization GO:0032880 76 0.012
single organism cellular localization GO:1902580 180 0.012
regulation of cell development GO:0060284 215 0.012
negative regulation of gene expression GO:0010629 387 0.012
embryonic axis specification GO:0000578 107 0.012
negative regulation of homeostatic process GO:0032845 2 0.012
regulation of nervous system development GO:0051960 248 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
oocyte construction GO:0007308 112 0.012
metal ion transport GO:0030001 74 0.012
forebrain development GO:0030900 2 0.011
positive regulation of synapse assembly GO:0051965 29 0.011
regulated secretory pathway GO:0045055 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
regionalization GO:0003002 416 0.011
limb development GO:0060173 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 2 0.011
multicellular organismal movement GO:0050879 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
visual behavior GO:0007632 18 0.011
Fly
nucleotide metabolic process GO:0009117 161 0.011
regulation of cellular amide metabolic process GO:0034248 39 0.011
response to acid chemical GO:0001101 25 0.011
secretion by cell GO:0032940 101 0.011
action potential GO:0001508 13 0.011
ovarian follicle cell development GO:0030707 248 0.011
intracellular mrna localization GO:0008298 66 0.011
regulation of neurogenesis GO:0050767 158 0.011
mitochondrion organization GO:0007005 65 0.011
organelle fission GO:0048285 340 0.011
visual learning GO:0008542 4 0.011
regulation of cellular response to stress GO:0080135 89 0.011
protein localization GO:0008104 284 0.011
spermatogenesis GO:0007283 200 0.011
urogenital system development GO:0001655 72 0.011
regulation of actin filament based process GO:0032970 42 0.011
compound eye morphogenesis GO:0001745 249 0.011
cellular divalent inorganic cation homeostasis GO:0072503 23 0.011
regulation of molecular function GO:0065009 217 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
dendrite development GO:0016358 204 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
carboxylic acid metabolic process GO:0019752 92 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
striated muscle myosin thick filament assembly GO:0071688 3 0.010
regulation of phosphatase activity GO:0010921 3 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
synaptic target recognition GO:0008039 45 0.010
regulation of synaptic vesicle exocytosis GO:2000300 3 0.010
central nervous system development GO:0007417 201 0.010
humoral immune response GO:0006959 117 0.010
positive regulation of protein import into nucleus GO:0042307 21 0.010
lipid metabolic process GO:0006629 121 0.010
cell proliferation GO:0008283 299 0.010

Gad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.022
neuromuscular disease DOID:440 0 0.012
neuropathy DOID:870 0 0.012