Drosophila melanogaster

122 known processes

sec8 (Dmel_CG2095)

CG2095 gene product from transcript CG2095-RA

(Aliases: CG2095,Sec8,Sec8p,Dmel\CG2095,dsec8)

sec8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokinetic process GO:0032506 27 0.993
cytoskeleton dependent cytokinesis GO:0061640 81 0.990
meiotic cytokinesis GO:0033206 33 0.975
regulation of protein complex disassembly GO:0043244 29 0.941
ovarian follicle cell migration GO:0007297 121 0.927
spermatogenesis GO:0007283 200 0.894
negative regulation of protein depolymerization GO:1901880 23 0.864
cytokinesis GO:0000910 90 0.836
meiosis ii cytokinesis GO:0007111 11 0.829
nuclear division GO:0000280 332 0.825
protein depolymerization GO:0051261 31 0.818
border follicle cell migration GO:0007298 113 0.804
meiosis i cytokinesis GO:0007110 12 0.800
synapse organization GO:0050808 196 0.792
cell division GO:0051301 248 0.778
contractile ring contraction GO:0036213 12 0.742
meiosis ii GO:0007135 23 0.741
regulation of protein depolymerization GO:1901879 27 0.736
spindle organization GO:0007051 253 0.699
negative regulation of microtubule depolymerization GO:0007026 21 0.687
spermatid development GO:0007286 98 0.671
cellular protein complex disassembly GO:0043624 35 0.664
spindle stabilization GO:0043146 14 0.631
cellularization GO:0007349 90 0.602
organelle fission GO:0048285 340 0.594
regulation of microtubule depolymerization GO:0031114 24 0.558
epithelial cell differentiation GO:0030855 322 0.552
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.504
actin cytoskeleton organization GO:0030036 206 0.498
male gamete generation GO:0048232 201 0.493
columnar cuboidal epithelial cell development GO:0002066 249 0.455
regulation of spindle organization GO:0090224 17 0.453
actomyosin contractile ring contraction GO:0000916 12 0.412
spermatid differentiation GO:0048515 114 0.379
cellular component disassembly GO:0022411 46 0.374
regulation of cell cycle GO:0051726 291 0.361
meiotic spindle stabilization GO:0043147 8 0.337
intracellular transport GO:0046907 228 0.332
meiotic cell cycle process GO:1903046 132 0.332
protein complex disassembly GO:0043241 36 0.324
establishment of localization in cell GO:0051649 402 0.293
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.285
microtubule depolymerization GO:0007019 25 0.272
cellular macromolecule localization GO:0070727 220 0.271
regulation of synapse structure and activity GO:0050803 128 0.259
epithelial cell development GO:0002064 274 0.249
negative regulation of protein complex disassembly GO:0043242 23 0.244
meiotic nuclear division GO:0007126 151 0.238
negative regulation of cytoskeleton organization GO:0051494 30 0.236
appendage morphogenesis GO:0035107 397 0.232
cell migration GO:0016477 238 0.226
regulation of cell cycle process GO:0010564 181 0.225
regulation of organelle organization GO:0033043 196 0.225
actomyosin structure organization GO:0031032 56 0.224
regulation of microtubule cytoskeleton organization GO:0070507 41 0.208
mitotic nuclear division GO:0007067 213 0.198
protein complex biogenesis GO:0070271 201 0.196
regulation of mitotic cell cycle GO:0007346 190 0.172
regulation of microtubule based process GO:0032886 49 0.169
anterior posterior axis specification embryo GO:0008595 103 0.163
nucleotide metabolic process GO:0009117 161 0.159
cellular response to heat GO:0034605 24 0.153
sperm individualization GO:0007291 48 0.152
neuromuscular junction development GO:0007528 149 0.149
segmentation GO:0035282 207 0.131
striated muscle cell differentiation GO:0051146 90 0.124
single organism intracellular transport GO:1902582 207 0.123
meiosis i GO:0007127 59 0.121
meiotic spindle organization GO:0000212 36 0.118
mitotic cell cycle phase transition GO:0044772 138 0.116
meiotic cell cycle GO:0051321 171 0.116
anterior posterior axis specification GO:0009948 109 0.115
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.114
regulation of cell cycle phase transition GO:1901987 130 0.109
actin filament based process GO:0030029 220 0.106
negative regulation of cellular component organization GO:0051129 108 0.102
synapse assembly GO:0007416 143 0.094
dendrite morphogenesis GO:0048813 199 0.094
rna splicing GO:0008380 83 0.093
protein localization GO:0008104 284 0.092
regulation of multicellular organismal development GO:2000026 414 0.091
intracellular signal transduction GO:0035556 300 0.087
blastoderm segmentation GO:0007350 159 0.086
muscle cell differentiation GO:0042692 103 0.085
regulation of cell death GO:0010941 173 0.082
spindle assembly GO:0051225 80 0.080
axonogenesis GO:0007409 290 0.080
endosomal transport GO:0016197 44 0.080
epithelium migration GO:0090132 148 0.078
regulation of synapse organization GO:0050807 110 0.075
positive regulation of cellular biosynthetic process GO:0031328 316 0.074
microtubule polymerization or depolymerization GO:0031109 39 0.072
epithelial cell migration GO:0010631 148 0.071
mitotic cytokinesis GO:0000281 50 0.071
macromolecular complex disassembly GO:0032984 37 0.071
single organism cellular localization GO:1902580 180 0.070
regulation of mitotic cell cycle phase transition GO:1901990 130 0.069
ovarian follicle cell development GO:0030707 248 0.069
macromolecular complex assembly GO:0065003 256 0.069
regulation of cytoskeleton organization GO:0051493 89 0.068
anterior posterior pattern specification GO:0009952 136 0.065
wing disc morphogenesis GO:0007472 344 0.065
organophosphate metabolic process GO:0019637 195 0.065
small molecule metabolic process GO:0044281 305 0.065
synaptic transmission GO:0007268 288 0.064
rna splicing via transesterification reactions GO:0000375 73 0.062
post embryonic appendage morphogenesis GO:0035120 385 0.062
centrosome organization GO:0051297 163 0.061
organonitrogen compound metabolic process GO:1901564 318 0.061
axon development GO:0061564 297 0.059
imaginal disc derived wing morphogenesis GO:0007476 337 0.058
regulation of cellular localization GO:0060341 136 0.058
determination of adult lifespan GO:0008340 137 0.056
purine ribonucleoside metabolic process GO:0046128 127 0.055
vesicle mediated transport GO:0016192 381 0.054
cellular protein localization GO:0034613 160 0.054
ribonucleotide metabolic process GO:0009259 145 0.054
purine ribonucleotide catabolic process GO:0009154 109 0.050
synaptic growth at neuromuscular junction GO:0051124 119 0.047
microtubule organizing center organization GO:0031023 168 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.047
positive regulation of transport GO:0051050 92 0.046
compound eye development GO:0048749 307 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
purine containing compound metabolic process GO:0072521 155 0.044
purine nucleotide metabolic process GO:0006163 146 0.044
imaginal disc derived appendage development GO:0048737 399 0.044
regulation of nervous system development GO:0051960 248 0.044
regulation of cell division GO:0051302 72 0.044
purine nucleoside triphosphate metabolic process GO:0009144 119 0.044
cell maturation GO:0048469 144 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.043
morphogenesis of an epithelium GO:0002009 276 0.042
intracellular mrna localization GO:0008298 66 0.042
regulation of cell shape GO:0008360 113 0.042
cell motility GO:0048870 251 0.041
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
head development GO:0060322 135 0.041
ameboidal type cell migration GO:0001667 151 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.041
tripartite regional subdivision GO:0007351 103 0.040
secretion GO:0046903 109 0.039
negative regulation of organelle organization GO:0010639 56 0.039
organic substance transport GO:0071702 257 0.039
nucleoside metabolic process GO:0009116 127 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.038
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
proteolysis GO:0006508 192 0.037
cellular macromolecule catabolic process GO:0044265 136 0.037
ribose phosphate metabolic process GO:0019693 145 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.037
nucleoside triphosphate metabolic process GO:0009141 120 0.036
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.036
brain development GO:0007420 120 0.036
forebrain development GO:0030900 2 0.035
protein maturation GO:0051604 71 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
telencephalon development GO:0021537 2 0.034
embryo development ending in birth or egg hatching GO:0009792 152 0.034
cellular protein modification process GO:0006464 438 0.034
protein complex assembly GO:0006461 200 0.034
eye morphogenesis GO:0048592 260 0.033
glycosyl compound metabolic process GO:1901657 127 0.033
intracellular protein transport GO:0006886 104 0.033
embryonic axis specification GO:0000578 107 0.033
tissue migration GO:0090130 155 0.033
establishment of protein localization GO:0045184 163 0.032
oocyte axis specification GO:0007309 108 0.032
axis specification GO:0009798 167 0.031
embryonic development via the syncytial blastoderm GO:0001700 148 0.030
tissue morphogenesis GO:0048729 297 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
organelle assembly GO:0070925 198 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
maternal determination of anterior posterior axis embryo GO:0008358 74 0.030
cytoplasmic transport GO:0016482 130 0.029
developmental maturation GO:0021700 172 0.029
regulation of catabolic process GO:0009894 170 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
regulation of cell morphogenesis GO:0022604 163 0.029
protein catabolic process GO:0030163 101 0.029
growth GO:0040007 359 0.028
Worm
oocyte development GO:0048599 124 0.028
pole plasm rna localization GO:0007316 52 0.028
protein processing GO:0016485 68 0.028
neurotransmitter transport GO:0006836 37 0.027
rna localization GO:0006403 115 0.027
plasma membrane organization GO:0007009 26 0.027
chromatin assembly or disassembly GO:0006333 52 0.027
purine ribonucleoside catabolic process GO:0046130 112 0.027
muscle structure development GO:0061061 224 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
actomyosin contractile ring organization GO:0044837 10 0.026
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.026
rna processing GO:0006396 147 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
guanosine containing compound catabolic process GO:1901069 74 0.026
embryonic pattern specification GO:0009880 174 0.025
localization of cell GO:0051674 257 0.025
endocytic recycling GO:0032456 13 0.024
regulation of catalytic activity GO:0050790 185 0.024
actomyosin contractile ring assembly GO:0000915 10 0.024
heterocycle catabolic process GO:0046700 166 0.024
regulation of behavior GO:0050795 75 0.024
male meiosis cytokinesis GO:0007112 26 0.024
cell cycle checkpoint GO:0000075 95 0.024
regulation of nuclear division GO:0051783 58 0.024
regulation of programmed cell death GO:0043067 152 0.022
regulation of cell development GO:0060284 215 0.022
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.022
protein import into nucleus GO:0006606 51 0.022
gtp catabolic process GO:0006184 72 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
organic substance catabolic process GO:1901575 308 0.021
neuron recognition GO:0008038 101 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.021
dendrite development GO:0016358 204 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
cellular lipid metabolic process GO:0044255 83 0.021
regulation of transport GO:0051049 181 0.020
oocyte construction GO:0007308 112 0.020
cytoplasm organization GO:0007028 64 0.020
neurotransmitter secretion GO:0007269 35 0.020
eggshell formation GO:0030703 105 0.020
purine containing compound catabolic process GO:0072523 112 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
regulation of cellular component biogenesis GO:0044087 201 0.019
catabolic process GO:0009056 409 0.019
nucleoside catabolic process GO:0009164 112 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
endomembrane system organization GO:0010256 119 0.019
positive regulation of transcription dna templated GO:0045893 266 0.018
spermatocyte division GO:0048137 13 0.018
chorion containing eggshell formation GO:0007304 105 0.018
regulation of localization GO:0032879 275 0.018
regulation of nucleoside metabolic process GO:0009118 50 0.018
oocyte anterior posterior axis specification GO:0007314 72 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of phosphatase activity GO:0010921 3 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
nucleocytoplasmic transport GO:0006913 72 0.018
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.018
cellular catabolic process GO:0044248 372 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
cell type specific apoptotic process GO:0097285 38 0.017
positive regulation of endopeptidase activity GO:0010950 26 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
cell cycle phase transition GO:0044770 140 0.017
regulation of protein metabolic process GO:0051246 256 0.017
axon guidance GO:0007411 233 0.017
cell recognition GO:0008037 102 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
regulation of vesicle mediated transport GO:0060627 59 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
negative regulation of cell communication GO:0010648 223 0.016
negative regulation of signaling GO:0023057 219 0.016
regulation of endopeptidase activity GO:0052548 36 0.016
protein modification process GO:0036211 438 0.016
immune response GO:0006955 246 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
regulation of molecular function GO:0065009 217 0.016
negative regulation of response to stimulus GO:0048585 258 0.015
chromosome segregation GO:0007059 157 0.015
eye development GO:0001654 323 0.015
regulation of developmental growth GO:0048638 174 0.015
Worm
appendage development GO:0048736 401 0.015
syncytium formation by plasma membrane fusion GO:0000768 43 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of secretion GO:0051046 44 0.015
cellular protein catabolic process GO:0044257 83 0.015
gtp metabolic process GO:0046039 72 0.014
endocytosis GO:0006897 310 0.014
regulation of protein localization GO:0032880 76 0.014
regulation of protein catabolic process GO:0042176 55 0.014
asymmetric protein localization GO:0008105 33 0.014
death GO:0016265 284 0.014
protein transport GO:0015031 155 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
negative regulation of developmental process GO:0051093 201 0.014
regulation of embryonic development GO:0045995 68 0.014
muscle cell development GO:0055001 50 0.014
cation transport GO:0006812 110 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.013
regulation of endocytosis GO:0030100 37 0.013
response to other organism GO:0051707 293 0.013
mrna metabolic process GO:0016071 124 0.013
chromosome organization GO:0051276 360 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
regulation of cysteine type endopeptidase activity GO:2000116 27 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
sister chromatid segregation GO:0000819 92 0.013
multicellular organismal aging GO:0010259 140 0.013
regulation of apoptotic process GO:0042981 130 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
regulation of neurotransmitter levels GO:0001505 38 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
camera type eye development GO:0043010 4 0.013
negative regulation of catabolic process GO:0009895 36 0.013
rrna processing GO:0006364 3 0.012
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.012
nucleus organization GO:0006997 45 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
carbohydrate metabolic process GO:0005975 82 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
regulation of synapse assembly GO:0051963 94 0.012
eye photoreceptor cell development GO:0042462 81 0.012
regulation of proteolysis GO:0030162 87 0.012
neuroblast proliferation GO:0007405 74 0.012
response to heat GO:0009408 63 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
phagocytosis GO:0006909 215 0.012
spindle assembly involved in mitosis GO:0090307 50 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
regionalization GO:0003002 416 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.011
sensory organ morphogenesis GO:0090596 260 0.011
cell death GO:0008219 279 0.011
membrane organization GO:0061024 112 0.011
protein localization to membrane GO:0072657 19 0.011
dorsal appendage formation GO:0046843 47 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
protein import GO:0017038 55 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
adult locomotory behavior GO:0008344 76 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
pole plasm assembly GO:0007315 61 0.011
regulation of gtpase activity GO:0043087 44 0.011
positive regulation of organelle organization GO:0010638 65 0.011
stem cell proliferation GO:0072089 88 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
central nervous system development GO:0007417 201 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.010
regulation of chromosome organization GO:0033044 64 0.010
embryonic organ development GO:0048568 50 0.010
ion transport GO:0006811 145 0.010
striated muscle cell development GO:0055002 50 0.010
secretion by cell GO:0032940 101 0.010

sec8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
parkinson s disease DOID:14330 0 0.024
synucleinopathy DOID:0050890 0 0.024
central nervous system disease DOID:331 0 0.024
neurodegenerative disease DOID:1289 0 0.024
nervous system disease DOID:863 0 0.024