Drosophila melanogaster

78 known processes

RfC4 (Dmel_CG14999)

Replication factor C subunit 4

(Aliases: BEST:GH24992,l(3)rfc40,l(3)e20,l(3)dsl1,DmRFC4,rfc[40],154910_at,rfc4,Rfc40,l(3)dsl-1,CG14999,rfc,l(3)Rfc4,RfC40,l(3)64Ai,l(3)SG13,Rfc4,l(3)A1,l(3)SH17,Dmel\CG14999,rfc40)

RfC4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 1.000
chromosome segregation GO:0007059 157 0.999
dna metabolic process GO:0006259 227 0.998
chromosome organization GO:0051276 360 0.997
nuclear division GO:0000280 332 0.996
meiotic cell cycle process GO:1903046 132 0.980
sister chromatid segregation GO:0000819 92 0.963
dna replication GO:0006260 48 0.956
mitotic nuclear division GO:0007067 213 0.953
mitotic sister chromatid segregation GO:0000070 87 0.911
dna dependent dna replication GO:0006261 17 0.909
female meiotic division GO:0007143 70 0.898
mitotic chromosome condensation GO:0007076 22 0.889
telomere maintenance GO:0000723 21 0.887
meiotic chromosome segregation GO:0045132 59 0.881
regulation of neurogenesis GO:0050767 158 0.871
cellular response to dna damage stimulus GO:0006974 223 0.864
meiotic nuclear division GO:0007126 151 0.860
lateral inhibition GO:0046331 206 0.808
dna repair GO:0006281 54 0.794
double strand break repair GO:0006302 26 0.789
telomere capping GO:0016233 11 0.733
spindle organization GO:0007051 253 0.729
cell cell signaling involved in cell fate commitment GO:0045168 210 0.727
dna conformation change GO:0071103 105 0.690
chromosome condensation GO:0030261 41 0.636
meiotic cell cycle GO:0051321 171 0.612
regulation of cell cycle GO:0051726 291 0.473
mitotic cell cycle phase transition GO:0044772 138 0.444
mitotic spindle organization GO:0007052 220 0.384
regulation of mitotic cell cycle GO:0007346 190 0.332
spindle assembly involved in mitosis GO:0090307 50 0.315
centrosome cycle GO:0007098 137 0.296
regulation of cell development GO:0060284 215 0.282
spindle assembly GO:0051225 80 0.270
telomere organization GO:0032200 21 0.269
cellular catabolic process GO:0044248 372 0.247
chromatin modification GO:0016568 147 0.244
regulation of cell cycle phase transition GO:1901987 130 0.242
sister chromatid cohesion GO:0007062 18 0.221
dendrite development GO:0016358 204 0.207
macromolecular complex disassembly GO:0032984 37 0.201
single organism biosynthetic process GO:0044711 206 0.200
regulation of organelle organization GO:0033043 196 0.194
protein complex disassembly GO:0043241 36 0.187
dna packaging GO:0006323 91 0.184
immune response GO:0006955 246 0.164
ribonucleotide catabolic process GO:0009261 109 0.163
mitotic dna damage checkpoint GO:0044773 74 0.162
embryo development ending in birth or egg hatching GO:0009792 152 0.155
purine nucleoside catabolic process GO:0006152 112 0.151
nuclear dna replication GO:0033260 1 0.148
ribonucleotide metabolic process GO:0009259 145 0.147
nucleobase containing small molecule metabolic process GO:0055086 174 0.146
neuroblast proliferation GO:0007405 74 0.143
nucleotide catabolic process GO:0009166 109 0.139
gliogenesis GO:0042063 80 0.136
nucleoside phosphate metabolic process GO:0006753 162 0.135
nucleoside triphosphate catabolic process GO:0009143 108 0.128
meiosis i GO:0007127 59 0.127
meiotic spindle organization GO:0000212 36 0.126
spindle midzone assembly GO:0051255 4 0.124
body morphogenesis GO:0010171 2 0.124
establishment of organelle localization GO:0051656 122 0.120
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.118
dendrite morphogenesis GO:0048813 199 0.117
regulation of phosphorus metabolic process GO:0051174 210 0.115
organic cyclic compound catabolic process GO:1901361 168 0.111
ribonucleoside triphosphate catabolic process GO:0009203 108 0.111
cell cycle dna replication GO:0044786 23 0.110
oocyte differentiation GO:0009994 145 0.110
regulation of multicellular organismal development GO:2000026 414 0.108
dna recombination GO:0006310 32 0.108
ribonucleoside catabolic process GO:0042454 112 0.106
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.104
cell division GO:0051301 248 0.103
meiotic chromosome condensation GO:0010032 3 0.101
regulation of cell differentiation GO:0045595 302 0.098
double strand break repair via nonhomologous end joining GO:0006303 5 0.098
purine nucleotide catabolic process GO:0006195 109 0.095
nucleoside catabolic process GO:0009164 112 0.095
cellular component disassembly GO:0022411 46 0.090
ribose phosphate metabolic process GO:0019693 145 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.090
nucleobase containing compound catabolic process GO:0034655 165 0.089
aromatic compound catabolic process GO:0019439 166 0.088
chromatin organization GO:0006325 207 0.088
cell cycle phase transition GO:0044770 140 0.087
female meiosis chromosome segregation GO:0016321 33 0.086
protein dna complex assembly GO:0065004 63 0.085
rna processing GO:0006396 147 0.082
negative regulation of cell cycle GO:0045786 116 0.081
negative regulation of mitotic cell cycle GO:0045930 109 0.080
single organism cellular localization GO:1902580 180 0.080
negative regulation of cell cycle process GO:0010948 109 0.079
negative regulation of protein complex disassembly GO:0043242 23 0.078
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.078
purine containing compound metabolic process GO:0072521 155 0.077
purine nucleotide metabolic process GO:0006163 146 0.077
centrosome organization GO:0051297 163 0.076
nucleotide metabolic process GO:0009117 161 0.076
purine ribonucleotide catabolic process GO:0009154 109 0.076
purine nucleoside triphosphate catabolic process GO:0009146 108 0.074
negative regulation of meiotic cell cycle GO:0051447 2 0.072
covalent chromatin modification GO:0016569 106 0.069
purine ribonucleoside catabolic process GO:0046130 112 0.067
organelle assembly GO:0070925 198 0.066
phosphorylation GO:0016310 294 0.065
purine ribonucleotide metabolic process GO:0009150 145 0.063
recombinational repair GO:0000725 13 0.062
purine nucleoside metabolic process GO:0042278 127 0.062
positive regulation of organelle organization GO:0010638 65 0.062
development of primary sexual characteristics GO:0045137 50 0.062
cell cycle checkpoint GO:0000075 95 0.061
regulation of neuron differentiation GO:0045664 103 0.060
cell cycle g1 s phase transition GO:0044843 31 0.058
protein localization GO:0008104 284 0.058
regulation of cell cycle process GO:0010564 181 0.058
regulation of small gtpase mediated signal transduction GO:0051056 93 0.057
dna geometric change GO:0032392 16 0.057
purine ribonucleoside metabolic process GO:0046128 127 0.056
establishment of localization in cell GO:0051649 402 0.053
nucleoside phosphate catabolic process GO:1901292 110 0.053
negative regulation of biosynthetic process GO:0009890 277 0.052
positive regulation of neurogenesis GO:0050769 41 0.051
nucleoside metabolic process GO:0009116 127 0.051
macromolecule catabolic process GO:0009057 161 0.050
mitotic cell cycle checkpoint GO:0007093 88 0.050
regulation of dna metabolic process GO:0051052 34 0.050
purine nucleoside triphosphate metabolic process GO:0009144 119 0.049
regulation of cellular protein metabolic process GO:0032268 243 0.048
protein complex biogenesis GO:0070271 201 0.048
homeostatic process GO:0042592 199 0.047
dna replication initiation GO:0006270 6 0.046
negative regulation of cellular metabolic process GO:0031324 382 0.045
heterocycle catabolic process GO:0046700 166 0.045
glycosyl compound catabolic process GO:1901658 112 0.044
macromolecule methylation GO:0043414 45 0.044
cellular macromolecule catabolic process GO:0044265 136 0.043
single organism catabolic process GO:0044712 228 0.042
regulation of mitotic cell cycle phase transition GO:1901990 130 0.042
mitotic sister chromatid separation GO:0051306 30 0.041
protein alkylation GO:0008213 43 0.041
establishment of spindle orientation GO:0051294 18 0.041
reproductive structure development GO:0048608 74 0.040
nucleoside triphosphate metabolic process GO:0009141 120 0.040
organophosphate catabolic process GO:0046434 112 0.040
positive regulation of biosynthetic process GO:0009891 316 0.039
positive regulation of cell cycle GO:0045787 43 0.039
response to other organism GO:0051707 293 0.039
immune system process GO:0002376 347 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
positive regulation of cellular component organization GO:0051130 156 0.037
regulation of molecular function GO:0065009 217 0.037
immune system development GO:0002520 57 0.036
regulation of nervous system development GO:0051960 248 0.036
carbohydrate derivative catabolic process GO:1901136 118 0.036
cellular protein complex disassembly GO:0043624 35 0.036
regulation of chromatin organization GO:1902275 32 0.035
purine containing compound catabolic process GO:0072523 112 0.035
axon development GO:0061564 297 0.035
microtubule depolymerization GO:0007019 25 0.034
organelle localization GO:0051640 148 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.032
intracellular transport GO:0046907 228 0.032
positive regulation of nucleoside metabolic process GO:0045979 47 0.032
cell proliferation GO:0008283 299 0.032
small molecule metabolic process GO:0044281 305 0.031
gonad development GO:0008406 50 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
regulation of ras protein signal transduction GO:0046578 93 0.031
negative regulation of organelle organization GO:0010639 56 0.030
genitalia development GO:0048806 26 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.030
microtubule polymerization or depolymerization GO:0031109 39 0.030
positive regulation of signaling GO:0023056 243 0.030
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.029
regulation of purine nucleotide metabolic process GO:1900542 62 0.029
regulation of chromosome organization GO:0033044 64 0.029
intermediate filament cytoskeleton organization GO:0045104 1 0.028
gene silencing GO:0016458 138 0.028
protein transport GO:0015031 155 0.027
regulation of nucleotide metabolic process GO:0006140 62 0.027
response to biotic stimulus GO:0009607 294 0.027
regulation of hydrolase activity GO:0051336 97 0.026
methylation GO:0032259 47 0.026
cellular protein catabolic process GO:0044257 83 0.025
regulation of catalytic activity GO:0050790 185 0.025
chromosome organization involved in meiosis GO:0070192 10 0.025
positive regulation of mitotic cell cycle GO:0045931 34 0.025
catabolic process GO:0009056 409 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
glycosyl compound metabolic process GO:1901657 127 0.023
regulation of phosphatase activity GO:0010921 3 0.023
regulation of purine nucleotide catabolic process GO:0033121 48 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.023
regulation of localization GO:0032879 275 0.022
response to radiation GO:0009314 155 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
dna damage checkpoint GO:0000077 78 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.021
dna amplification GO:0006277 11 0.021
cellular protein modification process GO:0006464 438 0.021
eggshell chorion gene amplification GO:0007307 9 0.020
regulation of neuron projection development GO:0010975 69 0.020
histone modification GO:0016570 106 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
regulation of gtp catabolic process GO:0033124 44 0.020
reproductive system development GO:0061458 74 0.020
negative regulation of neuroblast proliferation GO:0007406 27 0.020
regulation of protein complex disassembly GO:0043244 29 0.020
neuroblast division GO:0055057 35 0.020
anatomical structure homeostasis GO:0060249 97 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regulation of heterochromatin assembly GO:0031445 8 0.019
regulation of mitotic sister chromatid segregation GO:0033047 28 0.019
regulation of protein metabolic process GO:0051246 256 0.019
positive regulation of hydrolase activity GO:0051345 78 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
eggshell formation GO:0030703 105 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.018
g2 dna damage checkpoint GO:0031572 69 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
innate immune response GO:0045087 144 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
sensory organ morphogenesis GO:0090596 260 0.017
maintenance of location GO:0051235 73 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
negative regulation of gene expression GO:0010629 387 0.017
regulation of microtubule depolymerization GO:0031114 24 0.016
spindle elongation GO:0051231 83 0.016
response to external biotic stimulus GO:0043207 293 0.016
larval development GO:0002164 104 0.016
neuron recognition GO:0008038 101 0.016
organophosphate metabolic process GO:0019637 195 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
vesicle mediated transport GO:0016192 381 0.016
regulation of nucleotide catabolic process GO:0030811 48 0.016
regulation of nucleoside metabolic process GO:0009118 50 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of cytoskeleton organization GO:0051493 89 0.015
ras protein signal transduction GO:0007265 88 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
meiotic dna double strand break formation GO:0042138 1 0.015
regulation of gtpase activity GO:0043087 44 0.015
axonogenesis GO:0007409 290 0.015
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
proteolysis GO:0006508 192 0.014
response to ionizing radiation GO:0010212 32 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
regulation of histone modification GO:0031056 20 0.014
histone lysine methylation GO:0034968 32 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of response to stress GO:0080134 200 0.014
regulation of cell division GO:0051302 72 0.013
organic substance catabolic process GO:1901575 308 0.013
metaphase anaphase transition of cell cycle GO:0044784 28 0.013
double strand break repair via homologous recombination GO:0000724 13 0.013
regulation of protein depolymerization GO:1901879 27 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
positive regulation of signal transduction GO:0009967 223 0.013
dna biosynthetic process GO:0071897 24 0.013
determination of adult lifespan GO:0008340 137 0.013
histone methylation GO:0016571 40 0.013
microtubule organizing center organization GO:0031023 168 0.013
protein dna complex subunit organization GO:0071824 86 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
macromolecular complex assembly GO:0065003 256 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
dna integrity checkpoint GO:0031570 81 0.012
male meiosis GO:0007140 52 0.012
protein methylation GO:0006479 43 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
aging GO:0007568 143 0.012
intracellular signal transduction GO:0035556 300 0.012
negative regulation of transcription dna templated GO:0045892 237 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
regulation of dendrite development GO:0050773 37 0.011
regulation of cell death GO:0010941 173 0.011
regulation of mitosis GO:0007088 56 0.011
cellularization GO:0007349 90 0.011
endocytosis GO:0006897 310 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
single organism intracellular transport GO:1902582 207 0.010
chromatin remodeling GO:0006338 72 0.010
negative regulation of signaling GO:0023057 219 0.010
protein modification process GO:0036211 438 0.010

RfC4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org