Drosophila melanogaster

44 known processes

Kdm4A (Dmel_CG15835)

Histone demethylase 4A

(Aliases: dJMJD2(1),Dmel\CG15835,dKDM4A,CG15835)

Kdm4A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of response to stimulus GO:0048584 323 0.097
cell division GO:0051301 248 0.077
regionalization GO:0003002 416 0.075
intracellular signal transduction GO:0035556 300 0.061
positive regulation of macromolecule metabolic process GO:0010604 405 0.056
cellular catabolic process GO:0044248 372 0.055
catabolic process GO:0009056 409 0.055
positive regulation of signaling GO:0023056 243 0.055
positive regulation of signal transduction GO:0009967 223 0.053
chromosome organization GO:0051276 360 0.052
organonitrogen compound metabolic process GO:1901564 318 0.049
regulation of phosphate metabolic process GO:0019220 210 0.049
Yeast
regulation of mitotic cell cycle GO:0007346 190 0.049
establishment of localization in cell GO:0051649 402 0.047
positive regulation of cell communication GO:0010647 250 0.047
post embryonic appendage morphogenesis GO:0035120 385 0.046
growth GO:0040007 359 0.045
organic substance transport GO:0071702 257 0.045
organic substance catabolic process GO:1901575 308 0.041
regulation of cell cycle GO:0051726 291 0.041
reproductive behavior GO:0019098 122 0.040
defense response to other organism GO:0098542 225 0.040
segmentation GO:0035282 207 0.039
nuclear division GO:0000280 332 0.038
regulation of mitotic cell cycle phase transition GO:1901990 130 0.038
mitotic cell cycle phase transition GO:0044772 138 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
Yeast
regulation of cell cycle phase transition GO:1901987 130 0.035
small molecule metabolic process GO:0044281 305 0.034
male gamete generation GO:0048232 201 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
multi organism reproductive behavior GO:0044705 121 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
Human Yeast
protein localization GO:0008104 284 0.033
oocyte differentiation GO:0009994 145 0.033
spermatogenesis GO:0007283 200 0.032
vesicle mediated transport GO:0016192 381 0.032
negative regulation of signal transduction GO:0009968 206 0.032
multi organism behavior GO:0051705 175 0.032
protein modification process GO:0036211 438 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
Human Yeast
defense response GO:0006952 300 0.031
response to abiotic stimulus GO:0009628 341 0.030
mating GO:0007618 120 0.030
cellular macromolecular complex assembly GO:0034622 153 0.030
regulation of cell cycle process GO:0010564 181 0.030
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
cell proliferation GO:0008283 299 0.029
Human
neurological system process GO:0050877 358 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.028
body morphogenesis GO:0010171 2 0.028
cellular protein modification process GO:0006464 438 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
Yeast
single organism intracellular transport GO:1902582 207 0.027
organelle fission GO:0048285 340 0.027
germarium derived egg chamber formation GO:0007293 101 0.026
multi multicellular organism process GO:0044706 123 0.026
mrna metabolic process GO:0016071 124 0.026
cell cycle checkpoint GO:0000075 95 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
Yeast
regulation of multicellular organismal development GO:2000026 414 0.026
Rat
axis specification GO:0009798 167 0.025
wing disc morphogenesis GO:0007472 344 0.025
regulation of synapse assembly GO:0051963 94 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
heterocycle catabolic process GO:0046700 166 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
oocyte development GO:0048599 124 0.024
compound eye morphogenesis GO:0001745 249 0.024
cell maturation GO:0048469 144 0.024
dna metabolic process GO:0006259 227 0.024
developmental maturation GO:0021700 172 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
Yeast
mating behavior GO:0007617 106 0.023
cellular macromolecule localization GO:0070727 220 0.023
oocyte axis specification GO:0007309 108 0.023
axonogenesis GO:0007409 290 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
Human Yeast
aromatic compound catabolic process GO:0019439 166 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
Yeast
spermatid differentiation GO:0048515 114 0.022
intracellular transport GO:0046907 228 0.022
modification dependent macromolecule catabolic process GO:0043632 79 0.022
chromatin remodeling GO:0006338 72 0.022
negative regulation of cell cycle phase transition GO:1901988 103 0.021
single organism cellular localization GO:1902580 180 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
macromolecular complex assembly GO:0065003 256 0.021
centrosome organization GO:0051297 163 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
appendage morphogenesis GO:0035107 397 0.021
neuron projection guidance GO:0097485 241 0.020
appendage development GO:0048736 401 0.020
single organism catabolic process GO:0044712 228 0.020
phosphorylation GO:0016310 294 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
brain development GO:0007420 120 0.020
regulation of cell development GO:0060284 215 0.020
Rat
immune system process GO:0002376 347 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
macromolecule catabolic process GO:0009057 161 0.019
negative regulation of gene expression GO:0010629 387 0.019
Human Yeast
chemotaxis GO:0006935 249 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
fertilization GO:0009566 26 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.019
mitotic nuclear division GO:0007067 213 0.019
microtubule organizing center organization GO:0031023 168 0.019
regulation of response to stress GO:0080134 200 0.019
regulation of protein metabolic process GO:0051246 256 0.019
organic acid metabolic process GO:0006082 103 0.019
endocytosis GO:0006897 310 0.019
axon development GO:0061564 297 0.019
regulation of cell proliferation GO:0042127 163 0.019
Human
chromatin organization GO:0006325 207 0.019
spindle organization GO:0007051 253 0.019
response to organic substance GO:0010033 284 0.018
anatomical structure homeostasis GO:0060249 97 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
Yeast
covalent chromatin modification GO:0016569 106 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
rna processing GO:0006396 147 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
establishment of protein localization GO:0045184 163 0.017
cell cycle phase transition GO:0044770 140 0.017
regulation of behavior GO:0050795 75 0.017
ras protein signal transduction GO:0007265 88 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
phagocytosis GO:0006909 215 0.017
aggressive behavior GO:0002118 63 0.017
cellular protein localization GO:0034613 160 0.017
nuclear transport GO:0051169 72 0.017
eye morphogenesis GO:0048592 260 0.017
organophosphate metabolic process GO:0019637 195 0.017
Yeast
positive regulation of biosynthetic process GO:0009891 316 0.016
Yeast
oxoacid metabolic process GO:0043436 103 0.016
amine metabolic process GO:0009308 12 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
innate immune response GO:0045087 144 0.016
axon guidance GO:0007411 233 0.016
protein complex biogenesis GO:0070271 201 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
intracellular protein transport GO:0006886 104 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
Human Yeast
regulation of notch signaling pathway GO:0008593 100 0.015
compound eye development GO:0048749 307 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
rna localization GO:0006403 115 0.015
homeostatic process GO:0042592 199 0.015
Yeast
dna damage checkpoint GO:0000077 78 0.015
localization of cell GO:0051674 257 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
protein transport GO:0015031 155 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
muscle attachment GO:0016203 36 0.014
response to biotic stimulus GO:0009607 294 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
central nervous system development GO:0007417 201 0.014
Rat
regulation of catalytic activity GO:0050790 185 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
sensory organ morphogenesis GO:0090596 260 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
regulation of localization GO:0032879 275 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
Human Yeast
photoreceptor cell differentiation GO:0046530 170 0.014
forebrain development GO:0030900 2 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
cell death GO:0008219 279 0.014
Rat
locomotory behavior GO:0007626 176 0.014
dna integrity checkpoint GO:0031570 81 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
mrna processing GO:0006397 104 0.014
positive regulation of gene expression GO:0010628 290 0.014
oocyte construction GO:0007308 112 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
histone lysine demethylation GO:0070076 6 0.013
organophosphate catabolic process GO:0046434 112 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
tube development GO:0035295 244 0.013
regulation of cell differentiation GO:0045595 302 0.013
Rat
single fertilization GO:0007338 24 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
chromatin modification GO:0016568 147 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
tube morphogenesis GO:0035239 191 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of developmental growth GO:0048638 174 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
Human Yeast
actin filament based process GO:0030029 220 0.013
developmental growth GO:0048589 280 0.013
telencephalon development GO:0021537 2 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
rna transport GO:0050658 46 0.013
negative regulation of developmental process GO:0051093 201 0.013
Rat
larval development GO:0002164 104 0.013
skeletal muscle organ development GO:0060538 48 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.012
head development GO:0060322 135 0.012
adult behavior GO:0030534 137 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
Mouse
proteolysis GO:0006508 192 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
gene silencing GO:0016458 138 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
gliogenesis GO:0042063 80 0.012
Rat
negative regulation of multicellular organismal process GO:0051241 142 0.012
Rat
pigment metabolic process GO:0042440 84 0.012
response to extracellular stimulus GO:0009991 116 0.012
Yeast Rat
response to oxygen containing compound GO:1901700 200 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of defense response GO:0031347 102 0.012
organelle assembly GO:0070925 198 0.012
positive regulation of catabolic process GO:0009896 105 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
negative regulation of cell communication GO:0010648 223 0.011
stem cell division GO:0017145 69 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
leg disc development GO:0035218 92 0.011
translation GO:0006412 69 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
Yeast
digestive tract development GO:0048565 149 0.011
protein dna complex assembly GO:0065004 63 0.011
notch signaling pathway GO:0007219 120 0.011
death GO:0016265 284 0.011
Rat
regulation of nervous system development GO:0051960 248 0.011
Rat
cell motility GO:0048870 251 0.011
anterior posterior pattern specification GO:0009952 136 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
multicellular organismal aging GO:0010259 140 0.011
Worm
spermatid development GO:0007286 98 0.011
meiotic cell cycle process GO:1903046 132 0.011
nucleoside catabolic process GO:0009164 112 0.011
cytoplasmic transport GO:0016482 130 0.011
photoreceptor cell development GO:0042461 96 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
protein alkylation GO:0008213 43 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
Yeast
mitotic spindle organization GO:0007052 220 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.010
negative regulation of signaling GO:0023057 219 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
nuclear export GO:0051168 24 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
Human Yeast
muscle organ development GO:0007517 127 0.010
nitrogen compound transport GO:0071705 85 0.010
dorsal ventral axis specification GO:0009950 66 0.010

Kdm4A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.010