Drosophila melanogaster

137 known processes

gpp (Dmel_CG42803)

grappa

(Aliases: BcDNA:SD05230,Dmel_CG33324,CG42803,grp,dDot1,l(3)sA3484,dDOT1L,l(3)03342,Dmel_CG10272,Dmel\CG42803,CG10272,CG33324,Gpp,anon-WO0118547.319)

gpp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.998
negative regulation of transcription dna templated GO:0045892 237 0.991
chromatin silencing GO:0006342 76 0.988
negative regulation of rna biosynthetic process GO:1902679 240 0.986
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.984
negative regulation of nucleic acid templated transcription GO:1903507 240 0.984
negative regulation of gene expression GO:0010629 387 0.978
negative regulation of gene expression epigenetic GO:0045814 77 0.960
negative regulation of biosynthetic process GO:0009890 277 0.958
negative regulation of rna metabolic process GO:0051253 251 0.958
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.953
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.936
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.935
gene silencing GO:0016458 138 0.904
negative regulation of cellular biosynthetic process GO:0031327 277 0.750
transcription from rna polymerase ii promoter GO:0006366 368 0.711
chromatin remodeling GO:0006338 72 0.679
negative regulation of cellular metabolic process GO:0031324 382 0.612
chromosome organization GO:0051276 360 0.466
chromatin mediated maintenance of transcription GO:0048096 7 0.465
regulation of gene expression epigenetic GO:0040029 128 0.450
chromatin organization GO:0006325 207 0.431
positive regulation of nucleic acid templated transcription GO:1903508 266 0.374
chromatin silencing at centromere GO:0030702 3 0.364
spermatogenesis GO:0007283 200 0.329
positive regulation of macromolecule metabolic process GO:0010604 405 0.321
positive regulation of rna metabolic process GO:0051254 271 0.296
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.283
mating GO:0007618 120 0.270
male courtship behavior veined wing generated song production GO:0045433 20 0.266
striated muscle cell differentiation GO:0051146 90 0.255
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.248
positive regulation of transcription dna templated GO:0045893 266 0.231
dendrite morphogenesis GO:0048813 199 0.222
taxis GO:0042330 304 0.218
striated muscle cell development GO:0055002 50 0.210
stem cell differentiation GO:0048863 117 0.169
neuron projection guidance GO:0097485 241 0.168
dendrite development GO:0016358 204 0.158
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.155
regionalization GO:0003002 416 0.153
positive regulation of rna biosynthetic process GO:1902680 266 0.150
chromatin modification GO:0016568 147 0.149
male courtship behavior veined wing extension GO:0048065 22 0.144
growth GO:0040007 359 0.135
positive regulation of gene expression GO:0010628 290 0.134
heart development GO:0007507 82 0.132
dna conformation change GO:0071103 105 0.131
axon development GO:0061564 297 0.127
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.125
regulation of antimicrobial humoral response GO:0002759 50 0.119
muscle structure development GO:0061061 224 0.118
molting cycle GO:0042303 56 0.108
negative regulation of cell differentiation GO:0045596 143 0.106
cell motility GO:0048870 251 0.106
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.101
cellular component assembly involved in morphogenesis GO:0010927 151 0.098
dna metabolic process GO:0006259 227 0.096
macromolecular complex assembly GO:0065003 256 0.095
negative regulation of developmental process GO:0051093 201 0.095
antimicrobial peptide production GO:0002775 46 0.093
r3 r4 cell differentiation GO:0048056 12 0.093
male courtship behavior veined wing vibration GO:0016545 21 0.091
chemotaxis GO:0006935 249 0.089
regulation of neurogenesis GO:0050767 158 0.089
cellular response to dna damage stimulus GO:0006974 223 0.088
morphogenesis of follicular epithelium GO:0016333 36 0.087
cellular protein modification process GO:0006464 438 0.087
positive regulation of biosynthetic process GO:0009891 316 0.084
regulation of molecular function GO:0065009 217 0.084
muscle cell development GO:0055001 50 0.084
r7 cell differentiation GO:0045466 43 0.080
negative regulation of response to stimulus GO:0048585 258 0.080
axonogenesis GO:0007409 290 0.079
branching involved in open tracheal system development GO:0060446 45 0.078
regulation of growth GO:0040008 233 0.078
dna methylation GO:0006306 4 0.077
humoral immune response GO:0006959 117 0.075
regulation of cellular protein metabolic process GO:0032268 243 0.074
epithelial cell differentiation GO:0030855 322 0.074
death GO:0016265 284 0.073
antimicrobial humoral response GO:0019730 99 0.072
urogenital system development GO:0001655 72 0.070
eye photoreceptor cell differentiation GO:0001754 145 0.069
immune system process GO:0002376 347 0.068
organonitrogen compound biosynthetic process GO:1901566 117 0.068
regulation of chromatin silencing GO:0031935 36 0.067
embryonic morphogenesis GO:0048598 206 0.067
dna alkylation GO:0006305 4 0.067
epithelial cell development GO:0002064 274 0.065
dna methylation or demethylation GO:0044728 4 0.065
malpighian tubule morphogenesis GO:0007443 44 0.064
female germ line stem cell asymmetric division GO:0048132 14 0.063
columnar cuboidal epithelial cell development GO:0002066 249 0.063
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.060
molting cycle chitin based cuticle GO:0007591 56 0.060
multi organism reproductive behavior GO:0044705 121 0.057
production of molecular mediator of immune response GO:0002440 46 0.057
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.057
axon guidance GO:0007411 233 0.056
male mating behavior GO:0060179 70 0.055
regulation of cellular component biogenesis GO:0044087 201 0.053
regulation of response to stress GO:0080134 200 0.051
muscle fiber development GO:0048747 12 0.050
ovarian follicle cell development GO:0030707 248 0.050
regulation of immune system process GO:0002682 176 0.048
stem cell development GO:0048864 79 0.048
central nervous system development GO:0007417 201 0.048
cellular macromolecular complex assembly GO:0034622 153 0.048
response to organic substance GO:0010033 284 0.048
reproductive system development GO:0061458 74 0.047
protein complex assembly GO:0006461 200 0.047
regulation of tube size GO:0035150 46 0.046
brain development GO:0007420 120 0.046
immune response GO:0006955 246 0.045
regulation of response to external stimulus GO:0032101 115 0.045
tissue death GO:0016271 102 0.044
positive regulation of endopeptidase activity GO:0010950 26 0.044
organonitrogen compound metabolic process GO:1901564 318 0.043
cranial nerve development GO:0021545 1 0.043
regulation of cell fate specification GO:0042659 27 0.043
reproductive structure development GO:0048608 74 0.042
development of primary sexual characteristics GO:0045137 50 0.042
mitotic cell cycle embryonic GO:0045448 38 0.042
germ line stem cell division GO:0042078 25 0.041
cellular response to reactive oxygen species GO:0034614 14 0.041
response to bacterium GO:0009617 198 0.041
photoreceptor cell differentiation GO:0046530 170 0.039
cell death GO:0008219 279 0.039
compound eye photoreceptor fate commitment GO:0001752 36 0.039
retina development in camera type eye GO:0060041 4 0.039
larval development GO:0002164 104 0.039
adult chitin containing cuticle pigmentation GO:0048085 16 0.038
neuron recognition GO:0008038 101 0.037
sex differentiation GO:0007548 81 0.036
renal system development GO:0072001 72 0.036
positive regulation of peptidase activity GO:0010952 29 0.036
eye photoreceptor cell development GO:0042462 81 0.036
negative regulation of signal transduction GO:0009968 206 0.035
germline stem cell asymmetric division GO:0098728 15 0.035
covalent chromatin modification GO:0016569 106 0.035
regulation of cuticle pigmentation GO:0048079 16 0.035
response to ecdysone GO:0035075 34 0.035
regulation of r7 cell differentiation GO:0045676 15 0.034
segment specification GO:0007379 33 0.034
single organism cellular localization GO:1902580 180 0.033
programmed cell death GO:0012501 257 0.033
regulation of cell death GO:0010941 173 0.032
response to abiotic stimulus GO:0009628 341 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
regulation of peptidase activity GO:0052547 39 0.032
negative regulation of cell communication GO:0010648 223 0.032
neurological system process GO:0050877 358 0.032
regulation of photoreceptor cell differentiation GO:0046532 34 0.031
chromatin assembly GO:0031497 48 0.030
protein complex biogenesis GO:0070271 201 0.030
muscle organ development GO:0007517 127 0.029
regulation of cell fate commitment GO:0010453 29 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
tissue morphogenesis GO:0048729 297 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
determination of adult lifespan GO:0008340 137 0.029
eye development GO:0001654 323 0.029
response to biotic stimulus GO:0009607 294 0.028
regulation of cell differentiation GO:0045595 302 0.028
histolysis GO:0007559 102 0.028
cell migration GO:0016477 238 0.028
response to oxygen containing compound GO:1901700 200 0.028
peptidyl lysine modification GO:0018205 57 0.028
defense response GO:0006952 300 0.027
regulation of nervous system development GO:0051960 248 0.027
regulation of catabolic process GO:0009894 170 0.027
open tracheal system development GO:0007424 204 0.027
gonad development GO:0008406 50 0.027
negative regulation of meiotic cell cycle GO:0051447 2 0.027
positive regulation of catalytic activity GO:0043085 118 0.027
courtship behavior GO:0007619 68 0.026
morphogenesis of embryonic epithelium GO:0016331 94 0.026
cell recognition GO:0008037 102 0.026
compound eye photoreceptor development GO:0042051 78 0.026
single organism behavior GO:0044708 391 0.026
respiratory system development GO:0060541 213 0.026
single organism biosynthetic process GO:0044711 206 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
dendrite guidance GO:0070983 21 0.026
branching morphogenesis of an epithelial tube GO:0048754 45 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
segmentation GO:0035282 207 0.025
ovarian follicle cell stalk formation GO:0030713 17 0.025
cellular amide metabolic process GO:0043603 80 0.025
methylation GO:0032259 47 0.025
response to external biotic stimulus GO:0043207 293 0.025
locomotory behavior GO:0007626 176 0.025
salivary gland histolysis GO:0035070 88 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
macromolecule methylation GO:0043414 45 0.025
embryonic development via the syncytial blastoderm GO:0001700 148 0.024
morphogenesis of a branching structure GO:0001763 45 0.024
response to sterol GO:0036314 34 0.024
apoptotic process GO:0006915 159 0.024
epithelial cell migration open tracheal system GO:0007427 32 0.024
regulation of multi organism process GO:0043900 131 0.024
regulation of synapse structure and activity GO:0050803 128 0.024
response to other organism GO:0051707 293 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
small molecule metabolic process GO:0044281 305 0.023
dorsal appendage formation GO:0046843 47 0.023
molting cycle process GO:0022404 29 0.023
telencephalon development GO:0021537 2 0.023
male courtship behavior GO:0008049 63 0.023
regulation of immune response GO:0050776 118 0.023
tube development GO:0035295 244 0.023
regulation of humoral immune response GO:0002920 51 0.023
positive regulation of protein metabolic process GO:0051247 128 0.022
gland development GO:0048732 191 0.022
regulation of immune effector process GO:0002697 52 0.022
terminal region determination GO:0007362 25 0.022
salivary gland morphogenesis GO:0007435 145 0.022
chorion containing eggshell formation GO:0007304 105 0.022
cellular response to nutrient levels GO:0031669 62 0.022
tripartite regional subdivision GO:0007351 103 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
myotube cell development GO:0014904 3 0.021
head development GO:0060322 135 0.021
regulation of protein modification process GO:0031399 112 0.021
regulation of apoptotic process GO:0042981 130 0.021
eggshell formation GO:0030703 105 0.021
positive regulation of molecular function GO:0044093 136 0.021
skeletal muscle fiber development GO:0048741 3 0.021
regulation of organelle organization GO:0033043 196 0.021
gland morphogenesis GO:0022612 145 0.021
protein modification process GO:0036211 438 0.021
regulation of anatomical structure size GO:0090066 163 0.020
response to alcohol GO:0097305 95 0.020
regulation of response to biotic stimulus GO:0002831 63 0.020
multicellular organismal aging GO:0010259 140 0.020
actin filament based process GO:0030029 220 0.020
acetylcholine catabolic process GO:0006581 1 0.020
chromosome condensation GO:0030261 41 0.020
appendage development GO:0048736 401 0.020
pigmentation GO:0043473 75 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
photoreceptor cell development GO:0042461 96 0.020
cuticle development GO:0042335 86 0.020
digestive tract development GO:0048565 149 0.019
dna templated transcription elongation GO:0006354 18 0.019
protein targeting GO:0006605 64 0.019
developmental growth GO:0048589 280 0.019
vesicle mediated transport GO:0016192 381 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
response to oxidative stress GO:0006979 86 0.019
adult locomotory behavior GO:0008344 76 0.019
oxoacid metabolic process GO:0043436 103 0.019
cellular response to oxygen containing compound GO:1901701 79 0.019
organelle assembly GO:0070925 198 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.018
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
regulation of chromosome organization GO:0033044 64 0.018
response to superoxide GO:0000303 3 0.018
dna packaging GO:0006323 91 0.018
peptidyl lysine trimethylation GO:0018023 6 0.018
intracellular transport GO:0046907 228 0.017
border follicle cell migration GO:0007298 113 0.017
regulation of cellular amide metabolic process GO:0034248 39 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
cellular response to organic cyclic compound GO:0071407 32 0.017
lipid storage GO:0019915 38 0.017
endocytosis GO:0006897 310 0.017
renal tubule development GO:0061326 64 0.017
single organism catabolic process GO:0044712 228 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
lipid metabolic process GO:0006629 121 0.016
cell fate specification GO:0001708 71 0.016
regulation of heterochromatin assembly GO:0031445 8 0.016
response to organic cyclic compound GO:0014070 89 0.016
germarium derived female germ line cyst encapsulation GO:0030708 8 0.016
connective tissue development GO:0061448 3 0.016
stem cell maintenance GO:0019827 67 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
purine nucleoside biosynthetic process GO:0042451 3 0.016
leg disc morphogenesis GO:0007478 80 0.016
defense response to other organism GO:0098542 225 0.016
pole plasm protein localization GO:0007318 10 0.016
response to gravity GO:0009629 26 0.015
dna damage checkpoint GO:0000077 78 0.015
germ line stem cell maintenance GO:0030718 50 0.015
regulation of programmed cell death GO:0043067 152 0.015
positive regulation of immune response GO:0050778 63 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
localization of cell GO:0051674 257 0.015
sensory perception of mechanical stimulus GO:0050954 72 0.015
limb morphogenesis GO:0035108 1 0.015
embryonic hemopoiesis GO:0035162 26 0.015
proteolysis GO:0006508 192 0.015
cellular macromolecule localization GO:0070727 220 0.015
response to ketone GO:1901654 34 0.015
mitotic chromosome condensation GO:0007076 22 0.015
regulation of defense response GO:0031347 102 0.014
positive regulation of immune system process GO:0002684 68 0.014
cellular amine metabolic process GO:0044106 12 0.014
dna modification GO:0006304 5 0.014
mitotic spindle organization GO:0007052 220 0.014
catabolic process GO:0009056 409 0.014
forebrain development GO:0030900 2 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
developmental pigmentation GO:0048066 68 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
muscle cell differentiation GO:0042692 103 0.014
regulation of protein metabolic process GO:0051246 256 0.014
cardiovascular system development GO:0072358 82 0.014
cellular catabolic process GO:0044248 372 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.014
organophosphate catabolic process GO:0046434 112 0.014
germ cell migration GO:0008354 43 0.014
trunk segmentation GO:0035290 8 0.014
regulation of sequestering of triglyceride GO:0010889 3 0.013
peptidyl lysine methylation GO:0018022 16 0.013
histone ubiquitination GO:0016574 4 0.013
adult behavior GO:0030534 137 0.013
histone h3 k4 methylation GO:0051568 16 0.013
embryonic pattern specification GO:0009880 174 0.013
regulation of dna repair GO:0006282 5 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
negative regulation of neuroblast proliferation GO:0007406 27 0.013
phosphorylation GO:0016310 294 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
aggressive behavior GO:0002118 63 0.013
germ line cyst encapsulation GO:0048138 8 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
regulation of rna splicing GO:0043484 69 0.013
stem cell division GO:0017145 69 0.013
digestive tract morphogenesis GO:0048546 127 0.013
amine metabolic process GO:0009308 12 0.013
anterior posterior axis specification GO:0009948 109 0.013
ion transport GO:0006811 145 0.013
negative regulation of molecular function GO:0044092 51 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
embryonic axis specification GO:0000578 107 0.013
phagocytosis GO:0006909 215 0.013
small rna loading onto risc GO:0070922 6 0.013
negative regulation of growth GO:0045926 84 0.013
regulation of cellular response to oxidative stress GO:1900407 4 0.012
regulation of antimicrobial peptide production GO:0002784 44 0.012
regulation of synapse organization GO:0050807 110 0.012
protein dna complex subunit organization GO:0071824 86 0.012
response to oxygen radical GO:0000305 3 0.012
wing disc pattern formation GO:0035222 66 0.012
regulation of dna templated transcription in response to stress GO:0043620 4 0.012
digestive system development GO:0055123 149 0.012
leg disc development GO:0035218 92 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
regulation of tube diameter GO:0035296 14 0.012
outflow tract morphogenesis GO:0003151 4 0.012
sensory perception of sound GO:0007605 56 0.012
defense response to bacterium GO:0042742 178 0.012
negative regulation of erbb signaling pathway GO:1901185 29 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of catalytic activity GO:0050790 185 0.012
homeostatic process GO:0042592 199 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
cellular lipid metabolic process GO:0044255 83 0.012
male gamete generation GO:0048232 201 0.012
purine containing compound catabolic process GO:0072523 112 0.011
regulation of gene silencing GO:0060968 63 0.011
myoblast fusion GO:0007520 43 0.011
regulation of response to oxidative stress GO:1902882 4 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
protein modification by small protein removal GO:0070646 28 0.011
aging GO:0007568 143 0.011
ovarian follicle cell migration GO:0007297 121 0.011
neuron fate commitment GO:0048663 50 0.011
intracellular protein transport GO:0006886 104 0.011
positive regulation of chromatin silencing GO:0031937 16 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
malpighian tubule development GO:0072002 64 0.011
regulation of hydrolase activity GO:0051336 97 0.011
positive regulation of gene expression epigenetic GO:0045815 16 0.011
chemosensory behavior GO:0007635 106 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
camera type eye development GO:0043010 4 0.011
ameboidal type cell migration GO:0001667 151 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
neuroblast differentiation GO:0014016 29 0.011
developmental programmed cell death GO:0010623 138 0.011
dna repair GO:0006281 54 0.011
autophagy GO:0006914 108 0.011
autophagic cell death GO:0048102 83 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.011
female germ line cyst encapsulation GO:0048139 8 0.011
positive regulation of catabolic process GO:0009896 105 0.011
nucleoside metabolic process GO:0009116 127 0.011
circulatory system development GO:0072359 82 0.011
mesenchymal cell development GO:0014031 1 0.011
regulation of dna templated transcription elongation GO:0032784 17 0.011
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.011
protein localization GO:0008104 284 0.010
protein acetylation GO:0006473 39 0.010
negative regulation of signaling GO:0023057 219 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.010
reproductive behavior GO:0019098 122 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
protein methylation GO:0006479 43 0.010
erbb signaling pathway GO:0038127 58 0.010
vesicle fusion GO:0006906 19 0.010
r3 r4 cell fate commitment GO:0007464 10 0.010
neurotransmitter catabolic process GO:0042135 1 0.010
mushroom body development GO:0016319 70 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
positive regulation of organelle organization GO:0010638 65 0.010
regulation of cellular response to stress GO:0080135 89 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
specification of segmental identity trunk GO:0035292 7 0.010
response to radiation GO:0009314 155 0.010

gpp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.013