Drosophila melanogaster

39 known processes

DNApol-iota (Dmel_CG7602)

CG7602 gene product from transcript CG7602-RB

(Aliases: drad30B,AAF54198,CG7602,Dmel\CG7602,DNA Pol II-iota)

DNApol-iota biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.265
cellular catabolic process GO:0044248 372 0.218
chromosome organization GO:0051276 360 0.173
regionalization GO:0003002 416 0.156
regulation of cell differentiation GO:0045595 302 0.136
chromatin organization GO:0006325 207 0.108
positive regulation of rna biosynthetic process GO:1902680 266 0.102
protein modification process GO:0036211 438 0.085
imaginal disc derived appendage development GO:0048737 399 0.084
regulation of catalytic activity GO:0050790 185 0.082
negative regulation of transcription dna templated GO:0045892 237 0.081
positive regulation of transcription dna templated GO:0045893 266 0.075
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.074
regulation of phosphorus metabolic process GO:0051174 210 0.072
anterior posterior axis specification embryo GO:0008595 103 0.069
germarium derived egg chamber formation GO:0007293 101 0.067
chromatin modification GO:0016568 147 0.067
appendage development GO:0048736 401 0.063
cellular protein modification process GO:0006464 438 0.062
regulation of protein metabolic process GO:0051246 256 0.060
embryonic pattern specification GO:0009880 174 0.060
positive regulation of response to stimulus GO:0048584 323 0.059
negative regulation of gene expression GO:0010629 387 0.059
appendage morphogenesis GO:0035107 397 0.057
heterocycle catabolic process GO:0046700 166 0.053
covalent chromatin modification GO:0016569 106 0.052
negative regulation of cellular metabolic process GO:0031324 382 0.051
positive regulation of nucleic acid templated transcription GO:1903508 266 0.051
segmentation GO:0035282 207 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.049
regulation of cell death GO:0010941 173 0.049
intracellular signal transduction GO:0035556 300 0.049
regulation of programmed cell death GO:0043067 152 0.047
blastoderm segmentation GO:0007350 159 0.046
nucleobase containing compound catabolic process GO:0034655 165 0.045
positive regulation of rna metabolic process GO:0051254 271 0.045
oocyte development GO:0048599 124 0.045
positive regulation of protein metabolic process GO:0051247 128 0.045
cellular nitrogen compound catabolic process GO:0044270 165 0.045
negative regulation of nucleic acid templated transcription GO:1903507 240 0.044
proteolysis GO:0006508 192 0.043
purine nucleotide metabolic process GO:0006163 146 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.042
oocyte differentiation GO:0009994 145 0.042
histone modification GO:0016570 106 0.040
regulation of cellular protein metabolic process GO:0032268 243 0.039
negative regulation of cell communication GO:0010648 223 0.039
positive regulation of signal transduction GO:0009967 223 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
axis specification GO:0009798 167 0.037
dorsal ventral pattern formation GO:0009953 133 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.037
positive regulation of biosynthetic process GO:0009891 316 0.037
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.037
mitotic cell cycle checkpoint GO:0007093 88 0.037
response to radiation GO:0009314 155 0.036
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.036
protein ubiquitination GO:0016567 70 0.036
catabolic process GO:0009056 409 0.035
negative regulation of response to stimulus GO:0048585 258 0.035
regulation of cell cycle GO:0051726 291 0.035
positive regulation of catabolic process GO:0009896 105 0.035
cell death GO:0008219 279 0.034
peptidyl lysine modification GO:0018205 57 0.034
single organism catabolic process GO:0044712 228 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.034
regulation of proteolysis GO:0030162 87 0.033
organophosphate metabolic process GO:0019637 195 0.033
regulation of hydrolase activity GO:0051336 97 0.032
positive regulation of signaling GO:0023056 243 0.032
developmental maturation GO:0021700 172 0.032
wing disc morphogenesis GO:0007472 344 0.031
ribose phosphate metabolic process GO:0019693 145 0.031
embryonic axis specification GO:0000578 107 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
positive regulation of gene expression GO:0010628 290 0.031
post embryonic appendage morphogenesis GO:0035120 385 0.031
response to abiotic stimulus GO:0009628 341 0.031
positive regulation of cellular protein metabolic process GO:0032270 118 0.030
response to external biotic stimulus GO:0043207 293 0.030
ovarian follicle cell development GO:0030707 248 0.030
organic substance catabolic process GO:1901575 308 0.030
dna metabolic process GO:0006259 227 0.030
death GO:0016265 284 0.030
purine nucleoside catabolic process GO:0006152 112 0.030
regulation of catabolic process GO:0009894 170 0.030
protein maturation GO:0051604 71 0.029
nucleoside phosphate metabolic process GO:0006753 162 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
centrosome duplication GO:0051298 121 0.028
tripartite regional subdivision GO:0007351 103 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
purine nucleoside triphosphate metabolic process GO:0009144 119 0.028
anterior posterior axis specification GO:0009948 109 0.028
epithelial cell development GO:0002064 274 0.027
programmed cell death GO:0012501 257 0.027
ubiquitin dependent protein catabolic process GO:0006511 78 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
epithelial cell differentiation GO:0030855 322 0.027
regulation of cellular response to stress GO:0080135 89 0.027
regulation of intracellular signal transduction GO:1902531 236 0.026
ras protein signal transduction GO:0007265 88 0.026
negative regulation of developmental process GO:0051093 201 0.025
regulation of localization GO:0032879 275 0.025
response to light stimulus GO:0009416 124 0.025
positive regulation of cell communication GO:0010647 250 0.025
cell cycle phase transition GO:0044770 140 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
single organism biosynthetic process GO:0044711 206 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
body morphogenesis GO:0010171 2 0.024
regulation of cell development GO:0060284 215 0.024
aging GO:0007568 143 0.024
aromatic compound catabolic process GO:0019439 166 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
regulation of molecular function GO:0065009 217 0.023
regulation of response to stress GO:0080134 200 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
purine ribonucleotide catabolic process GO:0009154 109 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
regulation of nervous system development GO:0051960 248 0.022
protein catabolic process GO:0030163 101 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
nucleotide catabolic process GO:0009166 109 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
meiosis i GO:0007127 59 0.021
regulation of cell cycle process GO:0010564 181 0.021
determination of adult lifespan GO:0008340 137 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
neurological system process GO:0050877 358 0.021
organelle assembly GO:0070925 198 0.021
apoptotic process GO:0006915 159 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
negative regulation of cell cycle process GO:0010948 109 0.020
response to biotic stimulus GO:0009607 294 0.020
regulation of neuron differentiation GO:0045664 103 0.020
response to other organism GO:0051707 293 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
nucleotide metabolic process GO:0009117 161 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
anterior posterior pattern specification GO:0009952 136 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
modification dependent protein catabolic process GO:0019941 78 0.019
multicellular organismal aging GO:0010259 140 0.019
oocyte dorsal ventral axis specification GO:0007310 34 0.019
histone lysine methylation GO:0034968 32 0.019
response to bacterium GO:0009617 198 0.019
positive regulation of proteolysis GO:0045862 52 0.019
negative regulation of signal transduction GO:0009968 206 0.019
organophosphate catabolic process GO:0046434 112 0.019
phosphorylation GO:0016310 294 0.018
dna integrity checkpoint GO:0031570 81 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
regulation of peptidase activity GO:0052547 39 0.018
positive regulation of molecular function GO:0044093 136 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
macromolecule catabolic process GO:0009057 161 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
defense response GO:0006952 300 0.018
purine containing compound catabolic process GO:0072523 112 0.018
leg disc development GO:0035218 92 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
gtp catabolic process GO:0006184 72 0.017
small molecule metabolic process GO:0044281 305 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
immune system process GO:0002376 347 0.016
double strand break repair GO:0006302 26 0.016
regulation of cell cycle phase transition GO:1901987 130 0.016
peptidyl lysine acetylation GO:0018394 39 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
myotube differentiation GO:0014902 46 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
defense response to other organism GO:0098542 225 0.016
telomere maintenance GO:0000723 21 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
protein localization GO:0008104 284 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
cellular ketone metabolic process GO:0042180 24 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
regulation of apoptotic process GO:0042981 130 0.015
homeostatic process GO:0042592 199 0.015
regulation of stress activated mapk cascade GO:0032872 41 0.015
regulation of transport GO:0051049 181 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
oocyte construction GO:0007308 112 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
signal transduction in response to dna damage GO:0042770 3 0.014
regulation of mapk cascade GO:0043408 92 0.014
cell aging GO:0007569 2 0.014
cellular protein catabolic process GO:0044257 83 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of gtpase activity GO:0043087 44 0.014
negative regulation of cell cycle GO:0045786 116 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
regulation of gtp catabolic process GO:0033124 44 0.014
microtubule organizing center organization GO:0031023 168 0.014
cellular response to external stimulus GO:0071496 66 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
protein processing GO:0016485 68 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
oocyte axis specification GO:0007309 108 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
cell proliferation GO:0008283 299 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
rna localization GO:0006403 115 0.013
regulation of neurogenesis GO:0050767 158 0.013
purine containing compound metabolic process GO:0072521 155 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
muscle structure development GO:0061061 224 0.013
response to extracellular stimulus GO:0009991 116 0.013
signal transduction by phosphorylation GO:0023014 107 0.012
defense response to bacterium GO:0042742 178 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
gtp metabolic process GO:0046039 72 0.012
pigment metabolic process GO:0042440 84 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
muscle cell differentiation GO:0042692 103 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of chromosome organization GO:0033044 64 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
leg disc morphogenesis GO:0007478 80 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
cell cycle checkpoint GO:0000075 95 0.011
dorsal ventral axis specification GO:0009950 66 0.011
regulation of cell shape GO:0008360 113 0.011
histone lysine demethylation GO:0070076 6 0.011
response to lipopolysaccharide GO:0032496 4 0.011
immune response GO:0006955 246 0.011
response to nutrient levels GO:0031667 114 0.011
growth GO:0040007 359 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
methylation GO:0032259 47 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
lipid storage GO:0019915 38 0.011
asymmetric stem cell division GO:0098722 49 0.011
macromolecule methylation GO:0043414 45 0.011
mrna metabolic process GO:0016071 124 0.011
regulation of cell projection organization GO:0031344 92 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
internal peptidyl lysine acetylation GO:0018393 38 0.011
positive regulation of developmental process GO:0051094 143 0.010
dendrite development GO:0016358 204 0.010
organic substance transport GO:0071702 257 0.010
dna repair GO:0006281 54 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
spindle organization GO:0007051 253 0.010
ameboidal type cell migration GO:0001667 151 0.010
negative regulation of cell death GO:0060548 81 0.010
dna damage checkpoint GO:0000077 78 0.010
pigment biosynthetic process GO:0046148 36 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
nucleoside metabolic process GO:0009116 127 0.010

DNApol-iota disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
cardiovascular system disease DOID:1287 0 0.013
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.011
nervous system disease DOID:863 0 0.011