Drosophila melanogaster

134 known processes

Nedd4 (Dmel_CG42279)

CG42279 gene product from transcript CG42279-RJ

(Aliases: dNedd4,CG42279,nedd4,CG7555,Dmel\CG42279,CG32184,Dmel_CG7555,dNedd4-1,DNedd4,Dmel_CG32184)

Nedd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.985
neuron projection guidance GO:0097485 241 0.979
axon development GO:0061564 297 0.926
motor neuron axon guidance GO:0008045 58 0.858
central nervous system development GO:0007417 201 0.848
axon guidance GO:0007411 233 0.708
taxis GO:0042330 304 0.687
r7 cell differentiation GO:0045466 43 0.586
chemotaxis GO:0006935 249 0.555
neuron fate commitment GO:0048663 50 0.424
epidermal growth factor receptor signaling pathway GO:0007173 58 0.355
long term memory GO:0007616 62 0.342
neuron recognition GO:0008038 101 0.331
positive regulation of cell communication GO:0010647 250 0.319
regulation of nervous system development GO:0051960 248 0.314
formation of anatomical boundary GO:0048859 37 0.267
erbb signaling pathway GO:0038127 58 0.265
negative regulation of signaling GO:0023057 219 0.257
positive regulation of response to stimulus GO:0048584 323 0.255
negative regulation of signal transduction GO:0009968 206 0.244
positive regulation of signal transduction GO:0009967 223 0.241
negative regulation of response to stimulus GO:0048585 258 0.236
negative regulation of cell communication GO:0010648 223 0.234
catabolic process GO:0009056 409 0.231
dendrite morphogenesis GO:0048813 199 0.224
regulation of cell development GO:0060284 215 0.215
regulation of erbb signaling pathway GO:1901184 42 0.213
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.180
organic substance catabolic process GO:1901575 308 0.157
regulation of neuron differentiation GO:0045664 103 0.144
formation of organ boundary GO:0010160 30 0.133
regulation of cell differentiation GO:0045595 302 0.131
compound eye development GO:0048749 307 0.125
positive regulation of cell projection organization GO:0031346 29 0.121
exocrine system development GO:0035272 162 0.115
regulation of cell death GO:0010941 173 0.111
positive regulation of signaling GO:0023056 243 0.110
positive regulation of multicellular organismal process GO:0051240 143 0.107
dendrite guidance GO:0070983 21 0.103
body morphogenesis GO:0010171 2 0.100
regulation of catabolic process GO:0009894 170 0.099
regulation of intracellular signal transduction GO:1902531 236 0.095
negative regulation of developmental process GO:0051093 201 0.095
regulation of developmental growth GO:0048638 174 0.093
cellular catabolic process GO:0044248 372 0.090
eye development GO:0001654 323 0.090
response to external biotic stimulus GO:0043207 293 0.090
regulation of cell cycle GO:0051726 291 0.087
regulation of dendrite morphogenesis GO:0048814 28 0.081
positive regulation of neuron projection development GO:0010976 14 0.081
hair cell differentiation GO:0035315 47 0.081
dendrite development GO:0016358 204 0.078
negative regulation of nervous system development GO:0051961 92 0.075
epithelial cell migration open tracheal system GO:0007427 32 0.074
salivary gland development GO:0007431 162 0.073
embryonic development via the syncytial blastoderm GO:0001700 148 0.071
photoreceptor cell differentiation GO:0046530 170 0.071
phosphorylation GO:0016310 294 0.070
axon choice point recognition GO:0016198 26 0.068
cellular protein modification process GO:0006464 438 0.066
epithelial cell differentiation GO:0030855 322 0.062
axon midline choice point recognition GO:0016199 26 0.062
positive regulation of cellular catabolic process GO:0031331 95 0.061
gland morphogenesis GO:0022612 145 0.059
mapk cascade GO:0000165 107 0.059
adult locomotory behavior GO:0008344 76 0.058
locomotory behavior GO:0007626 176 0.057
cell migration GO:0016477 238 0.055
nuclear division GO:0000280 332 0.055
negative regulation of gene expression GO:0010629 387 0.053
secretion by cell GO:0032940 101 0.052
compound eye photoreceptor cell differentiation GO:0001751 140 0.051
gland development GO:0048732 191 0.051
skin development GO:0043588 65 0.050
regulation of cellular component biogenesis GO:0044087 201 0.050
macromolecule catabolic process GO:0009057 161 0.049
intracellular transport GO:0046907 228 0.048
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.048
establishment of localization in cell GO:0051649 402 0.047
positive regulation of cellular component organization GO:0051130 156 0.047
death GO:0016265 284 0.047
intracellular signal transduction GO:0035556 300 0.047
detection of stimulus GO:0051606 156 0.046
notch signaling pathway GO:0007219 120 0.045
dna metabolic process GO:0006259 227 0.045
protein modification by small protein conjugation or removal GO:0070647 106 0.045
growth GO:0040007 359 0.045
cellular nitrogen compound catabolic process GO:0044270 165 0.045
establishment of organelle localization GO:0051656 122 0.044
posttranscriptional regulation of gene expression GO:0010608 145 0.043
brain development GO:0007420 120 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
single organism intracellular transport GO:1902582 207 0.041
positive regulation of catabolic process GO:0009896 105 0.040
protein ubiquitination GO:0016567 70 0.040
purine ribonucleotide catabolic process GO:0009154 109 0.040
protein modification process GO:0036211 438 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
regulation of multicellular organismal development GO:2000026 414 0.039
negative regulation of cell development GO:0010721 62 0.038
head development GO:0060322 135 0.038
secretion GO:0046903 109 0.038
regulation of cellular localization GO:0060341 136 0.038
developmental programmed cell death GO:0010623 138 0.038
actin filament organization GO:0007015 126 0.037
protein localization GO:0008104 284 0.037
cell division GO:0051301 248 0.037
eye morphogenesis GO:0048592 260 0.036
actin cytoskeleton organization GO:0030036 206 0.036
protein modification by small protein conjugation GO:0032446 79 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.035
tissue morphogenesis GO:0048729 297 0.035
regulation of cell morphogenesis GO:0022604 163 0.035
negative regulation of biosynthetic process GO:0009890 277 0.033
negative regulation of cell differentiation GO:0045596 143 0.033
negative regulation of multicellular organismal process GO:0051241 142 0.033
eye photoreceptor cell differentiation GO:0001754 145 0.032
positive regulation of intracellular signal transduction GO:1902533 116 0.032
limb morphogenesis GO:0035108 1 0.032
single organism carbohydrate metabolic process GO:0044723 72 0.032
ribonucleotide catabolic process GO:0009261 109 0.032
regulation of cell migration GO:0030334 22 0.031
salivary gland morphogenesis GO:0007435 145 0.031
response to organic substance GO:0010033 284 0.030
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
ventral cord development GO:0007419 16 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.029
regulation of dendrite development GO:0050773 37 0.029
regulation of localization GO:0032879 275 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
dorsal ventral axon guidance GO:0033563 2 0.029
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.029
pigmentation GO:0043473 75 0.029
eye photoreceptor cell fate commitment GO:0042706 37 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.028
regulation of cellular component size GO:0032535 98 0.028
cranial nerve development GO:0021545 1 0.028
cellular protein complex assembly GO:0043623 71 0.027
signal transduction by phosphorylation GO:0023014 107 0.027
glycosyl compound catabolic process GO:1901658 112 0.027
regulation of axon guidance GO:1902667 10 0.027
protein catabolic process GO:0030163 101 0.026
small molecule metabolic process GO:0044281 305 0.026
kidney epithelium development GO:0072073 3 0.026
protein phosphorylation GO:0006468 169 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
regulation of cell motility GO:2000145 23 0.026
positive regulation of axon extension GO:0045773 2 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
regulation of notch signaling pathway GO:0008593 100 0.026
anterior posterior axis specification GO:0009948 109 0.026
proteolysis GO:0006508 192 0.025
single organism catabolic process GO:0044712 228 0.025
compound eye morphogenesis GO:0001745 249 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
regulation of cellular component movement GO:0051270 42 0.024
regulation of molecular function GO:0065009 217 0.024
regulation of organelle organization GO:0033043 196 0.024
purine nucleoside catabolic process GO:0006152 112 0.024
cell death GO:0008219 279 0.024
organelle fission GO:0048285 340 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
regulation of establishment of protein localization GO:0070201 61 0.023
regulation of cell projection organization GO:0031344 92 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
photoreceptor cell axon guidance GO:0072499 23 0.022
regulation of anatomical structure morphogenesis GO:0022603 242 0.022
smoothened signaling pathway GO:0007224 49 0.022
forebrain development GO:0030900 2 0.022
epidermal cell differentiation GO:0009913 51 0.022
defense response GO:0006952 300 0.022
autophagic vacuole assembly GO:0000045 2 0.022
axon extension involved in axon guidance GO:0048846 10 0.022
chaeta development GO:0022416 97 0.021
regulation of vesicle mediated transport GO:0060627 59 0.021
regulation of neuron projection development GO:0010975 69 0.021
response to alcohol GO:0097305 95 0.021
stem cell development GO:0048864 79 0.021
response to growth factor GO:0070848 31 0.021
limb development GO:0060173 1 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
central nervous system projection neuron axonogenesis GO:0021952 6 0.021
response to biotic stimulus GO:0009607 294 0.020
sensory organ morphogenesis GO:0090596 260 0.020
positive regulation of growth GO:0045927 75 0.020
regionalization GO:0003002 416 0.020
gene silencing GO:0016458 138 0.020
organic acid metabolic process GO:0006082 103 0.020
non sensory hair organization GO:0035316 47 0.020
appendage development GO:0048736 401 0.019
regulation of growth GO:0040008 233 0.019
regulation of transport GO:0051049 181 0.019
embryonic morphogenesis GO:0048598 206 0.019
aromatic compound catabolic process GO:0019439 166 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
membrane organization GO:0061024 112 0.019
purine containing compound catabolic process GO:0072523 112 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
mrna metabolic process GO:0016071 124 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cytoplasmic transport GO:0016482 130 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
regulation of cell proliferation GO:0042127 163 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
gliogenesis GO:0042063 80 0.018
positive regulation of neuron differentiation GO:0045666 26 0.018
purine ribonucleoside metabolic process GO:0046128 127 0.018
developmental maturation GO:0021700 172 0.018
olfactory bulb axon guidance GO:0071678 3 0.017
telencephalon development GO:0021537 2 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
cellular response to organic substance GO:0071310 132 0.017
camera type eye development GO:0043010 4 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
regulation of axonogenesis GO:0050770 32 0.017
head involution GO:0008258 35 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
membrane invagination GO:0010324 11 0.017
jak stat cascade GO:0007259 49 0.017
open tracheal system development GO:0007424 204 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
regulation of photoreceptor cell axon guidance GO:2000289 5 0.016
protein transport GO:0015031 155 0.016
cellular response to growth factor stimulus GO:0071363 30 0.016
detection of external stimulus GO:0009581 66 0.016
vesicle mediated transport GO:0016192 381 0.016
actin filament based process GO:0030029 220 0.016
reproductive system development GO:0061458 74 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
regulation of programmed cell death GO:0043067 152 0.016
positive regulation of cell migration GO:0030335 2 0.016
appendage morphogenesis GO:0035107 397 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.015
regulation of response to stress GO:0080134 200 0.015
blood circulation GO:0008015 26 0.015
heterocycle catabolic process GO:0046700 166 0.015
hindbrain development GO:0030902 2 0.015
regulation of mapk cascade GO:0043408 92 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
ameboidal type cell migration GO:0001667 151 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
regulation of cell size GO:0008361 63 0.015
purine nucleoside metabolic process GO:0042278 127 0.014
neurological system process GO:0050877 358 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of gtp catabolic process GO:0033124 44 0.014
negative regulation of developmental growth GO:0048640 64 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
carbohydrate metabolic process GO:0005975 82 0.014
anterior commissure morphogenesis GO:0021960 2 0.014
larval development GO:0002164 104 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
regulation of synaptic transmission GO:0050804 69 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
somatic muscle development GO:0007525 66 0.014
cell growth GO:0016049 108 0.014
regulation of secretion by cell GO:1903530 39 0.014
organic substance transport GO:0071702 257 0.013
neuroblast development GO:0014019 13 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
detection of light stimulus GO:0009583 58 0.013
negative regulation of immune system process GO:0002683 50 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
oocyte differentiation GO:0009994 145 0.013
positive regulation of nucleoside metabolic process GO:0045979 47 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
regulation of embryonic development GO:0045995 68 0.013
single organism behavior GO:0044708 391 0.013
establishment of cell polarity GO:0030010 40 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
programmed cell death GO:0012501 257 0.013
determination of dorsal ventral asymmetry GO:0048262 3 0.012
organelle assembly GO:0070925 198 0.012
single organism cellular localization GO:1902580 180 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
multi organism behavior GO:0051705 175 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
organelle localization GO:0051640 148 0.012
regulation of protein metabolic process GO:0051246 256 0.012
nucleotide catabolic process GO:0009166 109 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
gtp catabolic process GO:0006184 72 0.012
autophagy GO:0006914 108 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of intracellular transport GO:0032386 64 0.012
golgi vesicle transport GO:0048193 27 0.012
defense response to other organism GO:0098542 225 0.012
negative regulation of growth GO:0045926 84 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of dendrite development GO:1900006 9 0.012
epithelial cell development GO:0002064 274 0.012
regulation of synapse organization GO:0050807 110 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.011
synapse assembly GO:0007416 143 0.011
protein polymerization GO:0051258 42 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
lipid metabolic process GO:0006629 121 0.011
sodium ion transport GO:0006814 22 0.011
developmental pigmentation GO:0048066 68 0.011
regulation of cell shape GO:0008360 113 0.011
developmental growth GO:0048589 280 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
chaeta morphogenesis GO:0008407 42 0.011
glial cell development GO:0021782 27 0.011
retina development in camera type eye GO:0060041 4 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
anterior posterior pattern specification GO:0009952 136 0.011
biological adhesion GO:0022610 138 0.011
phagocytosis GO:0006909 215 0.011
cell proliferation GO:0008283 299 0.010
nucleus localization GO:0051647 34 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
tor signaling GO:0031929 32 0.010
spindle organization GO:0007051 253 0.010
negative regulation of axon extension GO:0030517 3 0.010
positive regulation of tor signaling GO:0032008 13 0.010
nucleocytoplasmic transport GO:0006913 72 0.010

Nedd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.010