Drosophila melanogaster

0 known processes

alpha-Est1 (Dmel_CG1031)

alpha-Esterase-1

(Aliases: A,aE1,alphaE1,CG1031,DmalphaE1,Est1,Dmel\CG1031)

alpha-Est1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to organophosphorus GO:0046683 2 0.109
Fly
catabolic process GO:0009056 409 0.101
Fly
response to external biotic stimulus GO:0043207 293 0.096
Fly
cellular catabolic process GO:0044248 372 0.095
Fly
ovarian follicle cell development GO:0030707 248 0.088
Fly
response to other organism GO:0051707 293 0.088
Fly
organonitrogen compound metabolic process GO:1901564 318 0.081
Fly
insecticide metabolic process GO:0017143 2 0.079
anion homeostasis GO:0055081 3 0.077
response to biotic stimulus GO:0009607 294 0.074
Fly
steroid catabolic process GO:0006706 1 0.068
epithelial cell development GO:0002064 274 0.066
Fly
spermatid differentiation GO:0048515 114 0.063
Fly
acetylcholine metabolic process GO:0008291 2 0.063
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.061
Fly
response to organic substance GO:0010033 284 0.061
Fly
epithelial cell differentiation GO:0030855 322 0.059
Fly
wing disc morphogenesis GO:0007472 344 0.054
Fly
small molecule metabolic process GO:0044281 305 0.053
Fly
hormone catabolic process GO:0042447 3 0.052
organic substance catabolic process GO:1901575 308 0.052
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.051
Fly
vitamin metabolic process GO:0006766 2 0.051
fat soluble vitamin metabolic process GO:0006775 1 0.051
neurological system process GO:0050877 358 0.049
spermatogenesis GO:0007283 200 0.049
Fly
neurotransmitter catabolic process GO:0042135 1 0.049
Fly
secondary metabolite catabolic process GO:0090487 1 0.047
neurotransmitter metabolic process GO:0042133 2 0.047
Fly
multi organism behavior GO:0051705 175 0.047
Fly
organonitrogen compound catabolic process GO:1901565 128 0.046
Fly
appendage development GO:0048736 401 0.046
Fly
response to abiotic stimulus GO:0009628 341 0.045
Fly
imaginal disc derived appendage development GO:0048737 399 0.044
Fly
single organism catabolic process GO:0044712 228 0.044
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.044
Fly
acetate ester metabolic process GO:1900619 2 0.043
Fly
growth GO:0040007 359 0.043
medium chain fatty acid metabolic process GO:0051791 1 0.042
defense response GO:0006952 300 0.042
Fly
epithelium migration GO:0090132 148 0.042
Fly
cellular ketone metabolic process GO:0042180 24 0.040
ethanolamine containing compound metabolic process GO:0042439 4 0.040
Fly
chromosome segregation GO:0007059 157 0.039
Fly
cell motility GO:0048870 251 0.039
Fly
border follicle cell migration GO:0007298 113 0.039
Fly
lauric acid metabolic process GO:0048252 1 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
homeostatic process GO:0042592 199 0.039
defense response to other organism GO:0098542 225 0.038
Fly
cell migration GO:0016477 238 0.038
Fly
axon guidance GO:0007411 233 0.038
Fly
regionalization GO:0003002 416 0.038
Fly
epithelial cell migration GO:0010631 148 0.037
Fly
ameboidal type cell migration GO:0001667 151 0.037
Fly
appendage morphogenesis GO:0035107 397 0.037
Fly
xenobiotic catabolic process GO:0042178 1 0.037
single organism behavior GO:0044708 391 0.037
organic acid metabolic process GO:0006082 103 0.036
choline catabolic process GO:0042426 1 0.035
Fly
kidney development GO:0001822 3 0.035
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.035
Fly
response to bacterium GO:0009617 198 0.035
toxin catabolic process GO:0009407 1 0.035
open tracheal system development GO:0007424 204 0.035
Fly
lipid metabolic process GO:0006629 121 0.035
carboxylic acid metabolic process GO:0019752 92 0.034
oxoacid metabolic process GO:0043436 103 0.034
regulation of anatomical structure size GO:0090066 163 0.033
Fly
response to lipopolysaccharide GO:0032496 4 0.033
response to nutrient levels GO:0031667 114 0.033
vitamin biosynthetic process GO:0009110 1 0.033
insecticide catabolic process GO:0046701 1 0.033
organelle fission GO:0048285 340 0.033
Fly
nuclear division GO:0000280 332 0.032
Fly
amine metabolic process GO:0009308 12 0.032
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
Fly
biological adhesion GO:0022610 138 0.032
Fly
developmental growth GO:0048589 280 0.031
female meiosis chromosome segregation GO:0016321 33 0.031
Fly
localization of cell GO:0051674 257 0.031
Fly
cellular amine metabolic process GO:0044106 12 0.031
Fly
single organism biosynthetic process GO:0044711 206 0.031
female meiotic division GO:0007143 70 0.031
Fly
acetylcholine catabolic process GO:0006581 1 0.031
Fly
cell adhesion involved in heart morphogenesis GO:0061343 12 0.030
Fly
respiratory system development GO:0060541 213 0.030
Fly
taxis GO:0042330 304 0.029
Fly
male gamete generation GO:0048232 201 0.029
Fly
polyol biosynthetic process GO:0046173 3 0.029
regulation of tube size GO:0035150 46 0.029
Fly
response to temperature stimulus GO:0009266 106 0.029
response to light stimulus GO:0009416 124 0.029
Fly
amine catabolic process GO:0009310 1 0.028
Fly
septate junction assembly GO:0019991 26 0.028
Fly
tissue migration GO:0090130 155 0.028
Fly
proteolysis GO:0006508 192 0.028
peptide metabolic process GO:0006518 80 0.027
drinking behavior GO:0042756 2 0.027
multi multicellular organism process GO:0044706 123 0.027
Fly
positive regulation of response to stimulus GO:0048584 323 0.027
response to extracellular stimulus GO:0009991 116 0.026
protein modification process GO:0036211 438 0.026
cellular biogenic amine catabolic process GO:0042402 1 0.026
Fly
ovarian follicle cell migration GO:0007297 121 0.026
Fly
toxin metabolic process GO:0009404 2 0.026
programmed cell death GO:0012501 257 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
positive regulation of gene expression GO:0010628 290 0.026
organic hydroxy compound metabolic process GO:1901615 83 0.025
Fly
camera type eye development GO:0043010 4 0.025
aging GO:0007568 143 0.025
Fly
morphogenesis of an epithelium GO:0002009 276 0.025
cellular response to chemical stimulus GO:0070887 199 0.024
axonogenesis GO:0007409 290 0.024
Fly
fat soluble vitamin biosynthetic process GO:0042362 1 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
axon development GO:0061564 297 0.023
Fly
death GO:0016265 284 0.023
neuron projection guidance GO:0097485 241 0.023
Fly
chemotaxis GO:0006935 249 0.023
Fly
cellular protein modification process GO:0006464 438 0.023
cell cell junction organization GO:0045216 55 0.023
Fly
sensory perception of smell GO:0007608 80 0.022
regulation of growth GO:0040008 233 0.022
meiotic cell cycle GO:0051321 171 0.022
Fly
regulation of multicellular organismal development GO:2000026 414 0.022
cellular lipid metabolic process GO:0044255 83 0.022
hormone metabolic process GO:0042445 33 0.022
sensory perception GO:0007600 196 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
cell death GO:0008219 279 0.022
mating behavior GO:0007617 106 0.022
Fly
intracellular signal transduction GO:0035556 300 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
response to oxygen containing compound GO:1901700 200 0.021
connective tissue development GO:0061448 3 0.021
heart development GO:0007507 82 0.021
Fly
body morphogenesis GO:0010171 2 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
lipid biosynthetic process GO:0008610 46 0.021
synaptic transmission GO:0007268 288 0.021
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.021
tissue morphogenesis GO:0048729 297 0.021
meiotic cell cycle process GO:1903046 132 0.021
Fly
organic substance transport GO:0071702 257 0.021
peripheral nervous system development GO:0007422 52 0.021
Fly
non sensory hair organization GO:0035316 47 0.021
Fly
imaginal disc derived wing hair organization GO:0035317 45 0.020
Fly
cell adhesion GO:0007155 136 0.020
Fly
telencephalon development GO:0021537 2 0.020
sensory perception of chemical stimulus GO:0007606 116 0.020
male mating behavior GO:0060179 70 0.020
Fly
multicellular organismal aging GO:0010259 140 0.020
Fly
response to nitrogen compound GO:1901698 90 0.020
histolysis GO:0007559 102 0.019
central nervous system development GO:0007417 201 0.019
choline metabolic process GO:0019695 1 0.019
Fly
immune system process GO:0002376 347 0.019
negative regulation of gene expression GO:0010629 387 0.019
cellular amide metabolic process GO:0043603 80 0.019
circadian behavior GO:0048512 76 0.019
alcohol metabolic process GO:0006066 25 0.019
Fly
compound eye morphogenesis GO:0001745 249 0.019
response to inorganic substance GO:0010035 44 0.019
forebrain development GO:0030900 2 0.019
defense response to bacterium GO:0042742 178 0.018
macromolecular complex assembly GO:0065003 256 0.018
cell proliferation GO:0008283 299 0.018
secondary metabolic process GO:0019748 75 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.017
skin development GO:0043588 65 0.017
Fly
rhythmic process GO:0048511 106 0.017
positive regulation of signal transduction GO:0009967 223 0.017
regulation of cell cycle GO:0051726 291 0.017
cardiovascular system development GO:0072358 82 0.017
Fly
eye development GO:0001654 323 0.017
response to radiation GO:0009314 155 0.017
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
positive regulation of cell motility GO:2000147 3 0.017
epidermis development GO:0008544 65 0.017
Fly
gland development GO:0048732 191 0.017
heart morphogenesis GO:0003007 32 0.017
Fly
tube development GO:0035295 244 0.017
protein localization GO:0008104 284 0.017
meiotic chromosome segregation GO:0045132 59 0.017
Fly
embryonic morphogenesis GO:0048598 206 0.017
adult behavior GO:0030534 137 0.017
cellularization GO:0007349 90 0.017
regulation of localization GO:0032879 275 0.017
response to mercury ion GO:0046689 3 0.017
chemical homeostasis GO:0048878 92 0.017
negative regulation of biosynthetic process GO:0009890 277 0.016
mating GO:0007618 120 0.016
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
ketone biosynthetic process GO:0042181 16 0.016
protein complex assembly GO:0006461 200 0.016
compound eye development GO:0048749 307 0.016
regulation of cell differentiation GO:0045595 302 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
Fly
digestive tract development GO:0048565 149 0.016
response to organic cyclic compound GO:0014070 89 0.016
developmental maturation GO:0021700 172 0.016
circadian sleep wake cycle GO:0042745 28 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
establishment of localization in cell GO:0051649 402 0.016
establishment of blood nerve barrier GO:0008065 2 0.016
Fly
circadian rhythm GO:0007623 105 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
neuron recognition GO:0008038 101 0.016
Fly
cellular macromolecule localization GO:0070727 220 0.016
lateral inhibition GO:0046331 206 0.016
sensory organ morphogenesis GO:0090596 260 0.015
eye morphogenesis GO:0048592 260 0.015
response to organonitrogen compound GO:0010243 75 0.015
acid secretion GO:0046717 1 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
cell recognition GO:0008037 102 0.015
Fly
spermatid development GO:0007286 98 0.015
aromatic compound catabolic process GO:0019439 166 0.015
cuticle development GO:0042335 86 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
heterocycle catabolic process GO:0046700 166 0.015
energy taxis GO:0009453 21 0.015
Fly
positive regulation of biosynthetic process GO:0009891 316 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
hair cell differentiation GO:0035315 47 0.015
Fly
maintenance of location GO:0051235 73 0.015
Fly
phototaxis GO:0042331 21 0.015
Fly
positive regulation of signaling GO:0023056 243 0.015
phosphorylation GO:0016310 294 0.015
monocarboxylic acid transport GO:0015718 3 0.015
response to endogenous stimulus GO:0009719 119 0.014
protein complex biogenesis GO:0070271 201 0.014
l amino acid import GO:0043092 2 0.014
feeding behavior GO:0007631 50 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
developmental programmed cell death GO:0010623 138 0.014
lipid localization GO:0010876 54 0.014
Fly
positive regulation of cell communication GO:0010647 250 0.014
regulation of tube architecture open tracheal system GO:0035152 68 0.014
Fly
organic hydroxy compound catabolic process GO:1901616 4 0.014
Fly
intracellular transport GO:0046907 228 0.014
ion transport GO:0006811 145 0.014
cellular homeostasis GO:0019725 80 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
single organism cellular localization GO:1902580 180 0.014
small molecule biosynthetic process GO:0044283 37 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
determination of adult lifespan GO:0008340 137 0.014
Fly
cellular response to dna damage stimulus GO:0006974 223 0.014
regulation of protein metabolic process GO:0051246 256 0.014
response to toxic substance GO:0009636 22 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of response to stress GO:0080134 200 0.014
alcohol biosynthetic process GO:0046165 14 0.014
establishment of protein localization GO:0045184 163 0.013
ecdysteroid metabolic process GO:0045455 19 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
synaptic target recognition GO:0008039 45 0.013
Fly
response to glucose GO:0009749 2 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of immune system process GO:0002682 176 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
ecdysteroid biosynthetic process GO:0045456 15 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
tissue death GO:0016271 102 0.013
apoptotic process GO:0006915 159 0.013
salivary gland morphogenesis GO:0007435 145 0.013
regulation of developmental growth GO:0048638 174 0.013
secretion GO:0046903 109 0.013
oxidation reduction process GO:0055114 123 0.013
regulation of tube size open tracheal system GO:0035151 43 0.013
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.013
androgen metabolic process GO:0008209 1 0.013
salivary gland histolysis GO:0035070 88 0.013
sperm individualization GO:0007291 48 0.013
exocrine system development GO:0035272 162 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
rhythmic behavior GO:0007622 76 0.013
circulatory system development GO:0072359 82 0.012
Fly
regulation of molecular function GO:0065009 217 0.012
regulation of programmed cell death GO:0043067 152 0.012
dna metabolic process GO:0006259 227 0.012
vesicle mediated transport GO:0016192 381 0.012
epidermal cell differentiation GO:0009913 51 0.012
Fly
response to monosaccharide GO:0034284 4 0.012
aggressive behavior GO:0002118 63 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
gland morphogenesis GO:0022612 145 0.012
digestive system development GO:0055123 149 0.012
regulation of catalytic activity GO:0050790 185 0.012
regulation of catabolic process GO:0009894 170 0.012
salivary gland development GO:0007431 162 0.012
response to hexose GO:0009746 3 0.012
regulation of organelle organization GO:0033043 196 0.012
positive regulation of cell migration GO:0030335 2 0.012
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.012
Fly
monocarboxylic acid metabolic process GO:0032787 29 0.012
chromosome organization GO:0051276 360 0.012
intracellular protein transport GO:0006886 104 0.012
sterol homeostasis GO:0055092 4 0.012
dorsal closure GO:0007391 79 0.012
macromolecule catabolic process GO:0009057 161 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
regulation of cell death GO:0010941 173 0.012
regulation of apoptotic process GO:0042981 130 0.012
renal system development GO:0072001 72 0.012
organophosphate metabolic process GO:0019637 195 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
regulation of cell cycle process GO:0010564 181 0.012
cell junction assembly GO:0034329 42 0.012
Fly
positive regulation of catabolic process GO:0009896 105 0.012
motor neuron axon guidance GO:0008045 58 0.012
Fly
multi organism reproductive behavior GO:0044705 121 0.012
Fly
phagocytosis GO:0006909 215 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
cellular macromolecule catabolic process GO:0044265 136 0.011
spindle organization GO:0007051 253 0.011
cell cell junction assembly GO:0007043 38 0.011
Fly
protein transport GO:0015031 155 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
negative regulation of developmental process GO:0051093 201 0.011
hormone biosynthetic process GO:0042446 20 0.011
wound healing GO:0042060 75 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
regulation of blood circulation GO:1903522 21 0.011
fatty acid metabolic process GO:0006631 20 0.011
cellular protein localization GO:0034613 160 0.011
lipid catabolic process GO:0016042 21 0.011
regulation of behavior GO:0050795 75 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
regulation of nervous system development GO:0051960 248 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
blood circulation GO:0008015 26 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
protein phosphorylation GO:0006468 169 0.011
nucleus organization GO:0006997 45 0.011
long chain fatty acid metabolic process GO:0001676 3 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
regulation of hormone levels GO:0010817 40 0.011
hindbrain development GO:0030902 2 0.011
ras protein signal transduction GO:0007265 88 0.011
regulation of transport GO:0051049 181 0.011
regulation of cell proliferation GO:0042127 163 0.011
retina development in camera type eye GO:0060041 4 0.011
mrna metabolic process GO:0016071 124 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
mitotic nuclear division GO:0007067 213 0.010
regulation of cell development GO:0060284 215 0.010
kidney epithelium development GO:0072073 3 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
wnt signaling pathway GO:0016055 98 0.010
autophagic cell death GO:0048102 83 0.010
segmentation GO:0035282 207 0.010
response to alkaloid GO:0043279 26 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
actin filament based process GO:0030029 220 0.010
negative regulation of cell communication GO:0010648 223 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
rna processing GO:0006396 147 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
regulation of defense response GO:0031347 102 0.010
mrna processing GO:0006397 104 0.010
cell junction organization GO:0034330 57 0.010
Fly
purine containing compound metabolic process GO:0072521 155 0.010

alpha-Est1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
cardiovascular system disease DOID:1287 0 0.033
hypertension DOID:10763 0 0.029
artery disease DOID:0050828 0 0.029
vascular disease DOID:178 0 0.029
nervous system disease DOID:863 0 0.029
essential hypertension DOID:10825 0 0.027
disease of metabolism DOID:0014667 0 0.021
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
acquired metabolic disease DOID:0060158 0 0.012
inherited metabolic disorder DOID:655 0 0.012