Drosophila melanogaster

113 known processes

A2bp1 (Dmel_CG32062)

Ataxin-2 binding protein 1

(Aliases: CG32062,dA2BP1,Dmel\CG32062,cg18441,BcDNA:GM06073,CG18441,CG14155)

A2bp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.581
post embryonic appendage morphogenesis GO:0035120 385 0.470
exocrine system development GO:0035272 162 0.335
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.255
rubidium ion transport GO:0035826 1 0.210
germ line stem cell maintenance GO:0030718 50 0.192
positive regulation of cellular biosynthetic process GO:0031328 316 0.189
stem cell maintenance GO:0019827 67 0.167
negative regulation of cell communication GO:0010648 223 0.150
positive regulation of biosynthetic process GO:0009891 316 0.150
gland development GO:0048732 191 0.149
regulation of cell development GO:0060284 215 0.142
regulation of cell differentiation GO:0045595 302 0.140
Mouse
sensory organ morphogenesis GO:0090596 260 0.118
single organism behavior GO:0044708 391 0.115
wing disc morphogenesis GO:0007472 344 0.112
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.110
gland morphogenesis GO:0022612 145 0.107
oocyte development GO:0048599 124 0.096
death GO:0016265 284 0.095
salivary gland development GO:0007431 162 0.094
imaginal disc derived wing vein specification GO:0007474 48 0.093
long term memory GO:0007616 62 0.091
muscle structure development GO:0061061 224 0.087
Zebrafish
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.079
chorion containing eggshell formation GO:0007304 105 0.077
salivary gland cell autophagic cell death GO:0035071 83 0.075
positive regulation of rna metabolic process GO:0051254 271 0.075
salivary gland morphogenesis GO:0007435 145 0.074
negative regulation of cell cycle phase transition GO:1901988 103 0.073
tissue morphogenesis GO:0048729 297 0.072
salivary gland histolysis GO:0035070 88 0.071
cell proliferation GO:0008283 299 0.067
regionalization GO:0003002 416 0.066
peptidyl threonine phosphorylation GO:0018107 2 0.064
dna metabolic process GO:0006259 227 0.062
nuclear division GO:0000280 332 0.058
stem cell differentiation GO:0048863 117 0.057
dna damage checkpoint GO:0000077 78 0.057
positive regulation of rna biosynthetic process GO:1902680 266 0.057
negative regulation of erbb signaling pathway GO:1901185 29 0.057
hemocyte migration GO:0035099 19 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.053
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.053
muscle organ development GO:0007517 127 0.053
Zebrafish
regulation of multicellular organismal development GO:2000026 414 0.049
Mouse
negative regulation of signaling GO:0023057 219 0.049
tube morphogenesis GO:0035239 191 0.049
negative regulation of receptor activity GO:2000272 3 0.048
learning or memory GO:0007611 141 0.048
homeostatic process GO:0042592 199 0.047
Mouse
head involution GO:0008258 35 0.044
small gtpase mediated signal transduction GO:0007264 88 0.044
positive regulation of multicellular organismal process GO:0051240 143 0.043
regulation of nervous system development GO:0051960 248 0.043
morphogenesis of an epithelium GO:0002009 276 0.043
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.042
cell death GO:0008219 279 0.042
regulation of localization GO:0032879 275 0.042
memory GO:0007613 94 0.042
spermatogenesis GO:0007283 200 0.042
autophagic cell death GO:0048102 83 0.042
tissue death GO:0016271 102 0.041
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.039
Mouse
positive regulation of gene expression GO:0010628 290 0.038
cytokinesis GO:0000910 90 0.036
regulation of cell proliferation GO:0042127 163 0.035
imaginal disc derived appendage development GO:0048737 399 0.035
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.035
protein modification process GO:0036211 438 0.034
adult behavior GO:0030534 137 0.034
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.033
tissue migration GO:0090130 155 0.033
regulation of cell cycle GO:0051726 291 0.032
immune system process GO:0002376 347 0.032
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.032
programmed cell death GO:0012501 257 0.032
oocyte differentiation GO:0009994 145 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
stem cell development GO:0048864 79 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
histolysis GO:0007559 102 0.030
appendage development GO:0048736 401 0.030
positive regulation of nervous system development GO:0051962 69 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
Human
negative regulation of signal transduction GO:0009968 206 0.030
response to abiotic stimulus GO:0009628 341 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
mitotic dna integrity checkpoint GO:0044774 75 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.028
Human
regulation of multi organism process GO:0043900 131 0.028
negative regulation of developmental process GO:0051093 201 0.028
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.028
head development GO:0060322 135 0.027
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.027
regulation of intracellular protein transport GO:0033157 46 0.026
regulation of neuron differentiation GO:0045664 103 0.026
intracellular signal transduction GO:0035556 300 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
dna integrity checkpoint GO:0031570 81 0.026
positive regulation of developmental process GO:0051094 143 0.025
neurological system process GO:0050877 358 0.025
Mouse
hemopoiesis GO:0030097 46 0.025
Mouse
digestive tract morphogenesis GO:0048546 127 0.025
negative regulation of protein metabolic process GO:0051248 85 0.025
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.025
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.025
regulation of mitotic cell cycle GO:0007346 190 0.024
negative regulation of response to stimulus GO:0048585 258 0.024
regulation of neurogenesis GO:0050767 158 0.024
ras protein signal transduction GO:0007265 88 0.023
establishment of localization in cell GO:0051649 402 0.023
bmp signaling pathway GO:0030509 27 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
maintenance of protein location in cell GO:0032507 26 0.023
positive regulation of cell development GO:0010720 61 0.022
eye development GO:0001654 323 0.022
eggshell chorion assembly GO:0007306 66 0.022
renal system process GO:0003014 12 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
nephron development GO:0072006 3 0.021
mapk cascade GO:0000165 107 0.021
cytoplasmic transport GO:0016482 130 0.021
maintenance of location in cell GO:0051651 28 0.021
immune response GO:0006955 246 0.021
dendrite morphogenesis GO:0048813 199 0.020
Mouse
positive regulation of cell communication GO:0010647 250 0.020
regulation of erbb signaling pathway GO:1901184 42 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
oocyte maturation GO:0001556 3 0.020
ion homeostasis GO:0050801 55 0.020
myotube cell development GO:0014904 3 0.020
Zebrafish
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.019
secretion GO:0046903 109 0.019
developmental programmed cell death GO:0010623 138 0.019
ovarian follicle cell development GO:0030707 248 0.019
regulation of wnt signaling pathway GO:0030111 68 0.019
cell activation GO:0001775 9 0.019
male gamete generation GO:0048232 201 0.019
rna processing GO:0006396 147 0.018
Zebrafish Mouse
protein modification by small protein removal GO:0070646 28 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
neuromuscular process GO:0050905 21 0.018
Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.018
multi organism behavior GO:0051705 175 0.018
Worm
forebrain development GO:0030900 2 0.018
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 81 0.018
regulation of cell junction assembly GO:1901888 2 0.017
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.017
central nervous system development GO:0007417 201 0.017
Zebrafish Mouse
sister chromatid segregation GO:0000819 92 0.017
skeletal muscle organ development GO:0060538 48 0.017
Zebrafish
negative regulation of wnt signaling pathway GO:0030178 28 0.017
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
Human
regulation of molecular function GO:0065009 217 0.017
cellular response to dna damage stimulus GO:0006974 223 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
anatomical structure homeostasis GO:0060249 97 0.016
protein transport GO:0015031 155 0.016
morphogenesis of a polarized epithelium GO:0001738 93 0.016
eye morphogenesis GO:0048592 260 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.016
rrna processing GO:0006364 3 0.016
tube development GO:0035295 244 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
cell maturation GO:0048469 144 0.016
peptidyl threonine modification GO:0018210 3 0.016
regulation of transport GO:0051049 181 0.016
regulation of cell cycle process GO:0010564 181 0.016
reproductive behavior GO:0019098 122 0.016
Worm
negative regulation of gene expression GO:0010629 387 0.016
Human
dendrite development GO:0016358 204 0.015
Mouse
cognition GO:0050890 141 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
negative regulation of insulin secretion GO:0046676 1 0.015
female germ line stem cell maintenance GO:0036099 8 0.015
axis specification GO:0009798 167 0.015
intracellular transport GO:0046907 228 0.015
response to oxidative stress GO:0006979 86 0.014
regulation of dendrite development GO:0050773 37 0.014
nuclear transcribed mrna catabolic process GO:0000956 24 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
locomotory behavior GO:0007626 176 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
brain development GO:0007420 120 0.014
Zebrafish Mouse
chromosome segregation GO:0007059 157 0.014
eggshell formation GO:0030703 105 0.014
cellular amide metabolic process GO:0043603 80 0.014
oocyte axis specification GO:0007309 108 0.014
cell recognition GO:0008037 102 0.014
defense response GO:0006952 300 0.014
oxoacid metabolic process GO:0043436 103 0.014
response to oxygen containing compound GO:1901700 200 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
catabolic process GO:0009056 409 0.013
cell junction assembly GO:0034329 42 0.013
cellular response to oxidative stress GO:0034599 28 0.013
cellular protein modification process GO:0006464 438 0.013
immune response activating signal transduction GO:0002757 2 0.013
torc1 signaling GO:0038202 12 0.013
embryonic hemopoiesis GO:0035162 26 0.013
positive regulation of signal transduction GO:0009967 223 0.013
response to monosaccharide GO:0034284 4 0.013
camera type eye development GO:0043010 4 0.013
peptidyl lysine acetylation GO:0018394 39 0.013
cell migration GO:0016477 238 0.013
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.013
response to osmotic stress GO:0006970 14 0.012
histone acetylation GO:0016573 38 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.012
intracellular protein transport GO:0006886 104 0.012
response to fungus GO:0009620 50 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
Human
cell cycle checkpoint GO:0000075 95 0.012
positive regulation of signaling GO:0023056 243 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
mitotic nuclear division GO:0007067 213 0.012
embryonic axis specification GO:0000578 107 0.012
negative regulation of cell cycle GO:0045786 116 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
response to oxygen levels GO:0070482 59 0.012
open tracheal system development GO:0007424 204 0.012
appendage morphogenesis GO:0035107 397 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
developmental maturation GO:0021700 172 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
aromatic compound catabolic process GO:0019439 166 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
negative regulation of protein modification process GO:0031400 29 0.011
nuclear transport GO:0051169 72 0.011
negative regulation of hormone biosynthetic process GO:0032353 1 0.011
proteolysis GO:0006508 192 0.011
response to organic substance GO:0010033 284 0.011
rna splicing GO:0008380 83 0.011
Zebrafish Mouse
positive regulation of innate immune response GO:0045089 38 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
r7 cell differentiation GO:0045466 43 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
convergent extension involved in gastrulation GO:0060027 2 0.010
amide biosynthetic process GO:0043604 42 0.010
stem cell proliferation GO:0072089 88 0.010
oocyte dorsal ventral axis specification GO:0007310 34 0.010
cellular protein localization GO:0034613 160 0.010
regulation of cellular response to oxidative stress GO:1900407 4 0.010
cell cycle phase transition GO:0044770 140 0.010
detection of stimulus involved in sensory perception GO:0050906 92 0.010
segment specification GO:0007379 33 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
negative regulation of catalytic activity GO:0043086 42 0.010

A2bp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.044