Drosophila melanogaster

169 known processes

C3G (Dmel_CG42328)

CG42328 gene product from transcript CG42328-RC

(Aliases: Dmel_CG14436,CG3126,CG42328,DC3-G,C(3)G,Dmel\CG42328,Dmel_CG3126,CG14436,DC3G)

C3G biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage development GO:0048737 399 0.936
eye development GO:0001654 323 0.918
negative regulation of response to stimulus GO:0048585 258 0.884
negative regulation of cell communication GO:0010648 223 0.875
imaginal disc derived appendage morphogenesis GO:0035114 395 0.838
compound eye development GO:0048749 307 0.828
regulation of cell differentiation GO:0045595 302 0.778
regulation of multicellular organismal development GO:2000026 414 0.771
wing disc morphogenesis GO:0007472 344 0.766
enzyme linked receptor protein signaling pathway GO:0007167 179 0.750
negative regulation of signaling GO:0023057 219 0.734
post embryonic appendage morphogenesis GO:0035120 385 0.709
compound eye morphogenesis GO:0001745 249 0.683
compound eye photoreceptor cell differentiation GO:0001751 140 0.679
imaginal disc derived wing morphogenesis GO:0007476 337 0.663
negative regulation of signal transduction GO:0009968 206 0.627
compound eye cone cell differentiation GO:0042675 13 0.598
tube development GO:0035295 244 0.578
response to oxidative stress GO:0006979 86 0.578
skeletal muscle organ development GO:0060538 48 0.576
appendage morphogenesis GO:0035107 397 0.568
negative regulation of erbb signaling pathway GO:1901185 29 0.559
negative regulation of developmental process GO:0051093 201 0.558
synapse organization GO:0050808 196 0.558
epidermal growth factor receptor signaling pathway GO:0007173 58 0.468
photoreceptor cell differentiation GO:0046530 170 0.465
regulation of erbb signaling pathway GO:1901184 42 0.463
eye morphogenesis GO:0048592 260 0.444
regulation of cell development GO:0060284 215 0.443
sensory organ morphogenesis GO:0090596 260 0.435
appendage development GO:0048736 401 0.414
erbb signaling pathway GO:0038127 58 0.394
negative regulation of gene expression GO:0010629 387 0.392
negative regulation of transcription dna templated GO:0045892 237 0.392
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.389
muscle structure development GO:0061061 224 0.387
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.381
exocrine system development GO:0035272 162 0.362
intracellular signal transduction GO:0035556 300 0.316
protein modification process GO:0036211 438 0.289
cellular protein modification process GO:0006464 438 0.271
tube morphogenesis GO:0035239 191 0.259
neuromuscular junction development GO:0007528 149 0.240
regionalization GO:0003002 416 0.230
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.228
synapse assembly GO:0007416 143 0.223
regulation of neurogenesis GO:0050767 158 0.210
axon development GO:0061564 297 0.205
negative regulation of multicellular organismal process GO:0051241 142 0.204
positive regulation of cell communication GO:0010647 250 0.184
gland development GO:0048732 191 0.183
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.181
salivary gland development GO:0007431 162 0.169
tissue morphogenesis GO:0048729 297 0.168
muscle attachment GO:0016203 36 0.160
transcription from rna polymerase ii promoter GO:0006366 368 0.151
axonogenesis GO:0007409 290 0.147
positive regulation of response to stimulus GO:0048584 323 0.145
phosphorylation GO:0016310 294 0.144
regulation of small gtpase mediated signal transduction GO:0051056 93 0.143
positive regulation of signal transduction GO:0009967 223 0.140
myoblast fusion GO:0007520 43 0.136
regulation of neuron differentiation GO:0045664 103 0.135
negative regulation of cell differentiation GO:0045596 143 0.128
negative regulation of nervous system development GO:0051961 92 0.127
immune system process GO:0002376 347 0.123
salivary gland morphogenesis GO:0007435 145 0.121
negative regulation of rna metabolic process GO:0051253 251 0.113
positive regulation of phosphate metabolic process GO:0045937 139 0.112
gland morphogenesis GO:0022612 145 0.109
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.109
pigmentation GO:0043473 75 0.104
regulation of intracellular signal transduction GO:1902531 236 0.102
cell maturation GO:0048469 144 0.099
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.098
secretion by cell GO:0032940 101 0.098
regulation of cell projection organization GO:0031344 92 0.097
axon guidance GO:0007411 233 0.097
chemotaxis GO:0006935 249 0.096
larval development GO:0002164 104 0.094
regulation of nervous system development GO:0051960 248 0.091
negative regulation of cellular biosynthetic process GO:0031327 277 0.083
protein processing GO:0016485 68 0.082
gastrulation GO:0007369 70 0.079
morphogenesis of an epithelium GO:0002009 276 0.079
positive regulation of gene expression GO:0010628 290 0.077
muscle organ development GO:0007517 127 0.077
positive regulation of signaling GO:0023056 243 0.075
cell death GO:0008219 279 0.074
cell migration GO:0016477 238 0.072
intracellular transport GO:0046907 228 0.071
digestive system development GO:0055123 149 0.071
positive regulation of nucleic acid templated transcription GO:1903508 266 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.069
programmed cell death GO:0012501 257 0.069
imaginal disc derived wing vein specification GO:0007474 48 0.069
endocytosis GO:0006897 310 0.068
branching morphogenesis of an epithelial tube GO:0048754 45 0.068
regulation of ras protein signal transduction GO:0046578 93 0.066
protein phosphorylation GO:0006468 169 0.066
taxis GO:0042330 304 0.066
cellular macromolecule localization GO:0070727 220 0.065
regulation of protein phosphorylation GO:0001932 64 0.064
localization of cell GO:0051674 257 0.063
developmental pigmentation GO:0048066 68 0.063
positive regulation of rna metabolic process GO:0051254 271 0.062
regulation of phosphorylation GO:0042325 147 0.060
protein import into nucleus GO:0006606 51 0.059
peptidyl amino acid modification GO:0018193 105 0.059
negative regulation of cell development GO:0010721 62 0.058
single organism nuclear import GO:1902593 51 0.058
compound eye cone cell fate commitment GO:0042676 5 0.058
synaptic growth at neuromuscular junction GO:0051124 119 0.058
regulation of phosphate metabolic process GO:0019220 210 0.058
negative regulation of neurogenesis GO:0050768 53 0.056
death GO:0016265 284 0.055
eye photoreceptor cell differentiation GO:0001754 145 0.055
regulation of cellular component biogenesis GO:0044087 201 0.055
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
regulation of cellular ketone metabolic process GO:0010565 3 0.054
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.053
epithelial cell migration GO:0010631 148 0.053
chromatin modification GO:0016568 147 0.053
regulation of immune system process GO:0002682 176 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
ameboidal type cell migration GO:0001667 151 0.051
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.050
somatic muscle development GO:0007525 66 0.050
small gtpase mediated signal transduction GO:0007264 88 0.049
oocyte development GO:0048599 124 0.049
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.048
proteolysis GO:0006508 192 0.048
establishment of localization in cell GO:0051649 402 0.047
positive regulation of biosynthetic process GO:0009891 316 0.047
instar larval development GO:0002168 55 0.047
cell proliferation GO:0008283 299 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.046
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.046
hematopoietic or lymphoid organ development GO:0048534 57 0.046
regulation of localization GO:0032879 275 0.046
stem cell differentiation GO:0048863 117 0.046
establishment or maintenance of cell polarity GO:0007163 167 0.046
negative regulation of immune system process GO:0002683 50 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
cell motility GO:0048870 251 0.043
mitotic dna damage checkpoint GO:0044773 74 0.042
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.042
regulation of protein metabolic process GO:0051246 256 0.042
regulation of notch signaling pathway GO:0008593 100 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
regulation of cellular amine metabolic process GO:0033238 3 0.040
cardiovascular system development GO:0072358 82 0.040
gene silencing GO:0016458 138 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.039
positive regulation of cellular amine metabolic process GO:0033240 0 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.039
positive regulation of developmental process GO:0051094 143 0.038
aging GO:0007568 143 0.038
neurological system process GO:0050877 358 0.038
epithelial cell development GO:0002064 274 0.038
organic substance catabolic process GO:1901575 308 0.037
intracellular protein transport GO:0006886 104 0.037
peptidyl tyrosine phosphorylation GO:0018108 24 0.036
ras protein signal transduction GO:0007265 88 0.036
defense response GO:0006952 300 0.036
regulation of transport GO:0051049 181 0.036
organic substance transport GO:0071702 257 0.036
ovarian follicle cell development GO:0030707 248 0.035
regulation of transferase activity GO:0051338 58 0.035
regulation of phosphatase activity GO:0010921 3 0.035
single organism behavior GO:0044708 391 0.034
amine metabolic process GO:0009308 12 0.034
notch signaling pathway GO:0007219 120 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
carboxylic acid metabolic process GO:0019752 92 0.033
regulation of organelle organization GO:0033043 196 0.033
urogenital system development GO:0001655 72 0.032
histolysis GO:0007559 102 0.032
nuclear transport GO:0051169 72 0.032
embryonic morphogenesis GO:0048598 206 0.032
single organism intracellular transport GO:1902582 207 0.032
digestive tract development GO:0048565 149 0.031
glial cell differentiation GO:0010001 35 0.031
protein targeting to nucleus GO:0044744 51 0.031
embryo development ending in birth or egg hatching GO:0009792 152 0.031
organelle localization GO:0051640 148 0.031
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
response to hydrogen peroxide GO:0042542 11 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
biological adhesion GO:0022610 138 0.029
regulation of epithelial cell proliferation GO:0050678 4 0.029
aromatic compound catabolic process GO:0019439 166 0.029
vesicle mediated transport GO:0016192 381 0.029
negative regulation of epithelial cell proliferation GO:0050680 4 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.028
cellular amine metabolic process GO:0044106 12 0.028
protein transport GO:0015031 155 0.028
chromosome segregation GO:0007059 157 0.028
positive regulation of phosphorylation GO:0042327 87 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
cellular response to oxidative stress GO:0034599 28 0.027
small molecule metabolic process GO:0044281 305 0.027
immune system development GO:0002520 57 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.027
r7 cell differentiation GO:0045466 43 0.027
regulation of cytoplasmic transport GO:1903649 47 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
chromatin organization GO:0006325 207 0.026
learning or memory GO:0007611 141 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
protein maturation GO:0051604 71 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
protein targeting GO:0006605 64 0.024
gastrulation with mouth forming first GO:0001703 36 0.024
camera type eye development GO:0043010 4 0.024
actin cytoskeleton organization GO:0030036 206 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
regulation of cellular localization GO:0060341 136 0.024
nuclear import GO:0051170 51 0.024
nucleocytoplasmic transport GO:0006913 72 0.024
regulation of developmental growth GO:0048638 174 0.023
regulation of protein modification process GO:0031399 112 0.023
organic acid metabolic process GO:0006082 103 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
jak stat cascade GO:0007259 49 0.022
regulation of synapse assembly GO:0051963 94 0.022
regulation of nucleotide catabolic process GO:0030811 48 0.022
regulation of cell proliferation GO:0042127 163 0.022
single organism cellular localization GO:1902580 180 0.022
digestive tract morphogenesis GO:0048546 127 0.022
myotube differentiation GO:0014902 46 0.022
developmental maturation GO:0021700 172 0.022
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.021
synaptic transmission GO:0007268 288 0.021
negative regulation of cell cycle GO:0045786 116 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
response to abiotic stimulus GO:0009628 341 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.020
response to organophosphorus GO:0046683 2 0.020
oxoacid metabolic process GO:0043436 103 0.020
lipid localization GO:0010876 54 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.020
regulation of molecular function GO:0065009 217 0.019
central nervous system development GO:0007417 201 0.019
peptidyl tyrosine modification GO:0018212 24 0.019
renal tubule morphogenesis GO:0061333 44 0.019
stem cell division GO:0017145 69 0.019
positive regulation of nucleotide catabolic process GO:0030813 46 0.019
axis specification GO:0009798 167 0.019
larval somatic muscle development GO:0007526 19 0.019
regulation of neuron projection development GO:0010975 69 0.019
growth GO:0040007 359 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
regulation of r7 cell differentiation GO:0045676 15 0.019
eye photoreceptor cell development GO:0042462 81 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
positive regulation of gtp catabolic process GO:0033126 43 0.018
single organism catabolic process GO:0044712 228 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
erk1 and erk2 cascade GO:0070371 39 0.018
regulation of cysteine type endopeptidase activity GO:2000116 27 0.017
catabolic process GO:0009056 409 0.017
positive regulation of immune system process GO:0002684 68 0.017
mrna metabolic process GO:0016071 124 0.017
cellular protein localization GO:0034613 160 0.017
pigment cell differentiation GO:0050931 3 0.017
positive regulation of cell motility GO:2000147 3 0.017
positive regulation of protein modification process GO:0031401 58 0.017
gastrulation involving germ band extension GO:0010004 36 0.017
positive regulation of ras gtpase activity GO:0032320 36 0.017
regulation of protein transport GO:0051223 57 0.017
cytoplasmic transport GO:0016482 130 0.016
response to glucose GO:0009749 2 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
protein import GO:0017038 55 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.016
positive regulation of nucleoside metabolic process GO:0045979 47 0.016
myotube cell development GO:0014904 3 0.016
oocyte differentiation GO:0009994 145 0.016
maintenance of location GO:0051235 73 0.016
regulation of catalytic activity GO:0050790 185 0.016
lipid storage GO:0019915 38 0.016
protein localization to nucleus GO:0034504 55 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
negative regulation of intracellular signal transduction GO:1902532 57 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
connective tissue development GO:0061448 3 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
regulation of mapk cascade GO:0043408 92 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
single organism biosynthetic process GO:0044711 206 0.015
actin filament based process GO:0030029 220 0.015
phagocytosis GO:0006909 215 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
sterol homeostasis GO:0055092 4 0.015
chromatin silencing GO:0006342 76 0.015
regulation of hydrolase activity GO:0051336 97 0.015
negative regulation of cell death GO:0060548 81 0.015
morphogenesis of a branching epithelium GO:0061138 45 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
open tracheal system development GO:0007424 204 0.015
positive regulation of protein metabolic process GO:0051247 128 0.014
epithelium migration GO:0090132 148 0.014
syncytium formation GO:0006949 43 0.014
regulation of photoreceptor cell differentiation GO:0046532 34 0.014
mrna splicing via spliceosome GO:0000398 73 0.014
heart development GO:0007507 82 0.014
regulation of cell motility GO:2000145 23 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
positive regulation of catabolic process GO:0009896 105 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.014
immune response GO:0006955 246 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
associative learning GO:0008306 65 0.013
actin filament organization GO:0007015 126 0.013
embryonic pattern specification GO:0009880 174 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
mapk cascade GO:0000165 107 0.013
negative regulation of protein modification process GO:0031400 29 0.013
regulation of protein kinase activity GO:0045859 51 0.013
lateral inhibition GO:0046331 206 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
response to radiation GO:0009314 155 0.013
nucleoside catabolic process GO:0009164 112 0.012
germ line stem cell maintenance GO:0030718 50 0.012
anatomical structure homeostasis GO:0060249 97 0.012
bmp signaling pathway GO:0030509 27 0.012
organelle fission GO:0048285 340 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
cell cycle arrest GO:0007050 4 0.012
determination of muscle attachment site GO:0016204 7 0.011
response to monosaccharide GO:0034284 4 0.011
establishment of tissue polarity GO:0007164 87 0.011
response to temperature stimulus GO:0009266 106 0.011
hemopoiesis GO:0030097 46 0.011
cellular response to nutrient levels GO:0031669 62 0.011
oxidation reduction process GO:0055114 123 0.011
negative regulation of developmental growth GO:0048640 64 0.011
secretion GO:0046903 109 0.011
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.011
regulation of programmed cell death GO:0043067 152 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
developmental growth GO:0048589 280 0.011
regulation of cell cycle GO:0051726 291 0.011
response to growth factor GO:0070848 31 0.011
tissue death GO:0016271 102 0.011
heterocycle catabolic process GO:0046700 166 0.011
nucleotide metabolic process GO:0009117 161 0.010
cell division GO:0051301 248 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010
negative regulation of smoothened signaling pathway GO:0045879 16 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.010
cellular protein catabolic process GO:0044257 83 0.010
rho protein signal transduction GO:0007266 14 0.010
organophosphate catabolic process GO:0046434 112 0.010
regulation of cell death GO:0010941 173 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010

C3G disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.062
disease of cellular proliferation DOID:14566 0 0.062
organ system cancer DOID:0050686 0 0.062
disease of anatomical entity DOID:7 0 0.030