Drosophila melanogaster

0 known processes

Prat2 (Dmel_CG10078)

Phosphoribosylamidotransferase 2

(Aliases: Dmel\CG10078,CG10078)

Prat2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment metabolic process GO:0042440 84 0.791
single organism biosynthetic process GO:0044711 206 0.379
Fly
carboxylic acid metabolic process GO:0019752 92 0.327
organic acid metabolic process GO:0006082 103 0.289
organic hydroxy compound metabolic process GO:1901615 83 0.224
organonitrogen compound metabolic process GO:1901564 318 0.213
Fly
oxoacid metabolic process GO:0043436 103 0.198
small molecule metabolic process GO:0044281 305 0.148
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.129
Fly
developmental pigmentation GO:0048066 68 0.105
organic hydroxy compound biosynthetic process GO:1901617 21 0.102
organic substance transport GO:0071702 257 0.097
cellular amino acid metabolic process GO:0006520 61 0.089
cellular ketone metabolic process GO:0042180 24 0.085
response to oxygen containing compound GO:1901700 200 0.084
phenol containing compound metabolic process GO:0018958 57 0.083
lipid metabolic process GO:0006629 121 0.083
single organism catabolic process GO:0044712 228 0.079
regulation of transport GO:0051049 181 0.076
xenobiotic catabolic process GO:0042178 1 0.070
camera type eye development GO:0043010 4 0.070
response to bacterium GO:0009617 198 0.070
vesicle mediated transport GO:0016192 381 0.069
phenol containing compound biosynthetic process GO:0046189 6 0.067
connective tissue development GO:0061448 3 0.067
nucleobase containing small molecule metabolic process GO:0055086 174 0.066
Fly
single organism carbohydrate metabolic process GO:0044723 72 0.066
dorsal ventral pattern formation GO:0009953 133 0.065
regulation of cellular ketone metabolic process GO:0010565 3 0.062
pigmentation GO:0043473 75 0.060
cellular response to chemical stimulus GO:0070887 199 0.056
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
phagocytosis GO:0006909 215 0.053
secondary metabolic process GO:0019748 75 0.053
nucleotide metabolic process GO:0009117 161 0.053
Fly
axis specification GO:0009798 167 0.051
positive regulation of biosynthetic process GO:0009891 316 0.050
cellular lipid metabolic process GO:0044255 83 0.049
endocytosis GO:0006897 310 0.048
toxin catabolic process GO:0009407 1 0.048
cellular carbohydrate biosynthetic process GO:0034637 7 0.048
muscle structure development GO:0061061 224 0.046
sensory perception of smell GO:0007608 80 0.046
mitotic cell cycle phase transition GO:0044772 138 0.045
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
organophosphate metabolic process GO:0019637 195 0.043
Fly
toxin metabolic process GO:0009404 2 0.043
regulation of epithelial cell proliferation GO:0050678 4 0.042
small molecule biosynthetic process GO:0044283 37 0.042
pigment biosynthetic process GO:0046148 36 0.041
response to temperature stimulus GO:0009266 106 0.041
response to biotic stimulus GO:0009607 294 0.041
response to abiotic stimulus GO:0009628 341 0.041
gland development GO:0048732 191 0.041
catechol containing compound biosynthetic process GO:0009713 3 0.041
carbohydrate biosynthetic process GO:0016051 17 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
learning or memory GO:0007611 141 0.040
mesenchymal cell differentiation GO:0048762 1 0.039
carbohydrate metabolic process GO:0005975 82 0.039
cognition GO:0050890 141 0.039
protein modification process GO:0036211 438 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
regulation of localization GO:0032879 275 0.038
regulation of cell cycle GO:0051726 291 0.036
cell division GO:0051301 248 0.036
Fly
purine containing compound metabolic process GO:0072521 155 0.036
Fly
organic substance catabolic process GO:1901575 308 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
dopamine metabolic process GO:0042417 7 0.035
defense response to gram negative bacterium GO:0050829 94 0.034
polyol biosynthetic process GO:0046173 3 0.034
positive regulation of lipid metabolic process GO:0045834 4 0.034
intracellular signal transduction GO:0035556 300 0.034
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.033
Fly
positive regulation of rna metabolic process GO:0051254 271 0.033
catabolic process GO:0009056 409 0.033
positive regulation of gene expression GO:0010628 290 0.033
sulfur compound metabolic process GO:0006790 59 0.033
positive regulation of cell communication GO:0010647 250 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
phosphorylation GO:0016310 294 0.031
homeostatic process GO:0042592 199 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
anion homeostasis GO:0055081 3 0.030
sensory perception of chemical stimulus GO:0007606 116 0.030
nitrogen compound transport GO:0071705 85 0.030
response to organic cyclic compound GO:0014070 89 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
dopamine biosynthetic process GO:0042416 3 0.029
single organism behavior GO:0044708 391 0.028
establishment of localization in cell GO:0051649 402 0.028
detection of stimulus GO:0051606 156 0.027
response to organic substance GO:0010033 284 0.027
production of molecular mediator of immune response GO:0002440 46 0.026
cellular macromolecule localization GO:0070727 220 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
cell cycle phase transition GO:0044770 140 0.026
ocellus pigment biosynthetic process GO:0008055 19 0.026
cellular carbohydrate metabolic process GO:0044262 22 0.025
adult behavior GO:0030534 137 0.025
response to glucose GO:0009749 2 0.025
response to lipopolysaccharide GO:0032496 4 0.025
hematopoietic progenitor cell differentiation GO:0002244 1 0.025
forebrain development GO:0030900 2 0.025
positive regulation of signaling GO:0023056 243 0.025
chemical homeostasis GO:0048878 92 0.025
cellular response to lipopolysaccharide GO:0071222 3 0.025
negative regulation of cell cycle GO:0045786 116 0.025
response to endogenous stimulus GO:0009719 119 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
neurological system process GO:0050877 358 0.024
defense response GO:0006952 300 0.024
toll signaling pathway GO:0008063 25 0.024
regulation of multi organism process GO:0043900 131 0.024
lipid biosynthetic process GO:0008610 46 0.024
regulation of catalytic activity GO:0050790 185 0.023
cellular ion homeostasis GO:0006873 39 0.023
protein localization to nucleus GO:0034504 55 0.023
response to hexose GO:0009746 3 0.023
dna metabolic process GO:0006259 227 0.023
response to nitrogen compound GO:1901698 90 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
regulation of organelle organization GO:0033043 196 0.023
cellular modified amino acid metabolic process GO:0006575 45 0.023
salivary gland development GO:0007431 162 0.022
cellular protein localization GO:0034613 160 0.022
positive regulation of signal transduction GO:0009967 223 0.022
eye pigment metabolic process GO:0042441 33 0.022
regulation of cell development GO:0060284 215 0.022
mesoderm development GO:0007498 78 0.022
dorsal ventral axis specification GO:0009950 66 0.021
oligosaccharide metabolic process GO:0009311 18 0.021
cellular homeostasis GO:0019725 80 0.021
myotube cell development GO:0014904 3 0.021
alpha amino acid metabolic process GO:1901605 20 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
cellular response to organic substance GO:0071310 132 0.021
body morphogenesis GO:0010171 2 0.021
nucleocytoplasmic transport GO:0006913 72 0.021
defense response to other organism GO:0098542 225 0.021
wing disc morphogenesis GO:0007472 344 0.021
immune effector process GO:0002252 98 0.021
defense response to bacterium GO:0042742 178 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
protein localization GO:0008104 284 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
multi organism behavior GO:0051705 175 0.020
cellular hormone metabolic process GO:0034754 23 0.020
cell cycle arrest GO:0007050 4 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
signal release GO:0023061 49 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
actin filament based process GO:0030029 220 0.020
response to nutrient levels GO:0031667 114 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
aggressive behavior GO:0002118 63 0.020
sulfur compound biosynthetic process GO:0044272 16 0.020
cellular response to molecule of bacterial origin GO:0071219 3 0.020
response to hormone GO:0009725 45 0.019
regulation of defense response GO:0031347 102 0.019
response to other organism GO:0051707 293 0.019
regulation of cell differentiation GO:0045595 302 0.019
cellular amine metabolic process GO:0044106 12 0.019
chromosome organization GO:0051276 360 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
cell cycle checkpoint GO:0000075 95 0.019
vitamin metabolic process GO:0006766 2 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
regulation of intracellular signal transduction GO:1902531 236 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
gland morphogenesis GO:0022612 145 0.018
cell death GO:0008219 279 0.018
response to organonitrogen compound GO:0010243 75 0.018
response to alcohol GO:0097305 95 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
cellular response to biotic stimulus GO:0071216 4 0.018
nuclear transport GO:0051169 72 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.017
antimicrobial humoral response GO:0019730 99 0.017
pigment metabolic process involved in pigmentation GO:0043474 33 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
cellular protein modification process GO:0006464 438 0.017
eye development GO:0001654 323 0.017
actin cytoskeleton organization GO:0030036 206 0.017
regulation of molecular function GO:0065009 217 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
macromolecular complex assembly GO:0065003 256 0.017
mitotic nuclear division GO:0007067 213 0.017
response to alkaloid GO:0043279 26 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
positive regulation of defense response GO:0031349 59 0.017
response to monosaccharide GO:0034284 4 0.017
exocrine system development GO:0035272 162 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
regulation of growth GO:0040008 233 0.016
regulation of protein metabolic process GO:0051246 256 0.016
regulation of response to stress GO:0080134 200 0.016
compound eye development GO:0048749 307 0.016
regulation of developmental growth GO:0048638 174 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of anatomical structure size GO:0090066 163 0.016
memory GO:0007613 94 0.016
spindle organization GO:0007051 253 0.016
regulation of cellular localization GO:0060341 136 0.016
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.016
death GO:0016265 284 0.016
immune response GO:0006955 246 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
negative regulation of gene expression GO:0010629 387 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
negative regulation of cell death GO:0060548 81 0.015
regulation of secretion GO:0051046 44 0.015
digestive system development GO:0055123 149 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
extracellular matrix assembly GO:0085029 13 0.015
ion homeostasis GO:0050801 55 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
protein transport GO:0015031 155 0.015
eye pigmentation GO:0048069 43 0.015
amine metabolic process GO:0009308 12 0.015
aromatic compound catabolic process GO:0019439 166 0.015
digestive tract development GO:0048565 149 0.015
chromatin modification GO:0016568 147 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
eye pigment biosynthetic process GO:0006726 32 0.015
cellular catabolic process GO:0044248 372 0.015
regulation of cell cycle process GO:0010564 181 0.015
neuron maturation GO:0042551 31 0.015
regulation of cell death GO:0010941 173 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
kidney development GO:0001822 3 0.015
regulation of neuron death GO:1901214 26 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
protein localization to organelle GO:0033365 82 0.015
neuron death GO:0070997 27 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
nucleoside monophosphate metabolic process GO:0009123 52 0.015
organelle fission GO:0048285 340 0.014
positive regulation of response to external stimulus GO:0032103 44 0.014
regulation of secretion by cell GO:1903530 39 0.014
response to extracellular stimulus GO:0009991 116 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
mushroom body development GO:0016319 70 0.014
response to drug GO:0042493 17 0.014
salivary gland morphogenesis GO:0007435 145 0.014
sensory perception GO:0007600 196 0.014
melanization defense response GO:0035006 45 0.014
polysaccharide biosynthetic process GO:0000271 7 0.014
mesenchymal cell development GO:0014031 1 0.014
circulatory system process GO:0003013 37 0.014
regulation of catabolic process GO:0009894 170 0.014
positive regulation of cell migration GO:0030335 2 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
autophagic cell death GO:0048102 83 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
nuclear division GO:0000280 332 0.013
regulation of neurogenesis GO:0050767 158 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
macromolecule catabolic process GO:0009057 161 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
gene silencing GO:0016458 138 0.013
response to external biotic stimulus GO:0043207 293 0.013
locomotory behavior GO:0007626 176 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
appendage development GO:0048736 401 0.013
regulation of apoptotic process GO:0042981 130 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
regulation of gene silencing GO:0060968 63 0.013
developmental maturation GO:0021700 172 0.013
positive regulation of transport GO:0051050 92 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.013
regulation of immune effector process GO:0002697 52 0.013
developmental growth GO:0048589 280 0.013
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
innate immune response GO:0045087 144 0.012
wound healing GO:0042060 75 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
sterol homeostasis GO:0055092 4 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
cellular response to monosaccharide stimulus GO:0071326 2 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of cell communication GO:0010648 223 0.012
skeletal muscle fiber development GO:0048741 3 0.012
negative regulation of signaling GO:0023057 219 0.012
histolysis GO:0007559 102 0.012
nucleoside metabolic process GO:0009116 127 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
positive regulation of cell motility GO:2000147 3 0.012
secretion by cell GO:0032940 101 0.012
negative regulation of signal transduction GO:0009968 206 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
eye morphogenesis GO:0048592 260 0.012
chromosome separation GO:0051304 42 0.012
molting cycle process GO:0022404 29 0.011
regionalization GO:0003002 416 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
regulation of immune system process GO:0002682 176 0.011
telencephalon development GO:0021537 2 0.011
intracellular transport GO:0046907 228 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
nuclear import GO:0051170 51 0.011
kidney epithelium development GO:0072073 3 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
positive regulation of multi organism process GO:0043902 40 0.011
reactive oxygen species metabolic process GO:0072593 22 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
protein processing GO:0016485 68 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
regulation of nervous system development GO:0051960 248 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
response to peptide GO:1901652 29 0.011
regulation of neuron differentiation GO:0045664 103 0.011
skeletal muscle organ development GO:0060538 48 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
Fly
regulation of programmed cell death GO:0043067 152 0.011
adult locomotory behavior GO:0008344 76 0.011
proteolysis GO:0006508 192 0.011
protein complex biogenesis GO:0070271 201 0.011
secretion GO:0046903 109 0.011
catecholamine biosynthetic process GO:0042423 3 0.011
renal system development GO:0072001 72 0.011
indole containing compound biosynthetic process GO:0042435 4 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
taxis GO:0042330 304 0.010
positive regulation of developmental process GO:0051094 143 0.010
protein maturation GO:0051604 71 0.010
positive regulation of stem cell differentiation GO:2000738 3 0.010
positive regulation of cell death GO:0010942 69 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
anatomical structure homeostasis GO:0060249 97 0.010
insecticide catabolic process GO:0046701 1 0.010
skeletal muscle tissue development GO:0007519 13 0.010
response to lipid GO:0033993 38 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
programmed cell death GO:0012501 257 0.010
cell adhesion mediated by integrin GO:0033627 12 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
Fly
small gtpase mediated signal transduction GO:0007264 88 0.010
negative regulation of organelle organization GO:0010639 56 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010

Prat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
disease of metabolism DOID:0014667 0 0.026
musculoskeletal system disease DOID:17 0 0.016
artery disease DOID:0050828 0 0.014
vascular disease DOID:178 0 0.014
cardiovascular system disease DOID:1287 0 0.014
diabetes mellitus DOID:9351 0 0.013
type 2 diabetes mellitus DOID:9352 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
glucose metabolism disease DOID:4194 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
inherited metabolic disorder DOID:655 0 0.012
hypertension DOID:10763 0 0.011