Drosophila melanogaster

37 known processes

Vmat (Dmel_CG33528)

Vesicular monoamine transporter

(Aliases: CG6119,DVMAT,CG6139,CG33528,l(2)SH0459,dVMAT,VMAT,l(2)SH2 0459,Dmel\CG33528,DVMAT-A)

Vmat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to gravity GO:0009629 26 0.993
mating behavior GO:0007617 106 0.990
mating GO:0007618 120 0.980
male courtship behavior veined wing extension GO:0048065 22 0.976
gravitaxis GO:0042332 26 0.941
male courtship behavior veined wing vibration GO:0016545 21 0.916
multicellular organismal reproductive behavior GO:0033057 110 0.897
rhythmic behavior GO:0007622 76 0.888
multi organism reproductive behavior GO:0044705 121 0.880
reproductive behavior GO:0019098 122 0.870
locomotory behavior GO:0007626 176 0.838
negative gravitaxis GO:0048060 7 0.814
multi organism behavior GO:0051705 175 0.719
multi multicellular organism process GO:0044706 123 0.666
courtship behavior GO:0007619 68 0.645
synaptic transmission GO:0007268 288 0.540
single organism behavior GO:0044708 391 0.528
male mating behavior GO:0060179 70 0.498
regulation of neurotransmitter levels GO:0001505 38 0.498
taxis GO:0042330 304 0.488
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.455
circadian behavior GO:0048512 76 0.386
larval behavior GO:0030537 42 0.385
neuromuscular junction development GO:0007528 149 0.375
growth GO:0040007 359 0.365
regulation of growth GO:0040008 233 0.364
rhythmic process GO:0048511 106 0.351
potassium ion transport GO:0006813 20 0.327
male courtship behavior GO:0008049 63 0.294
neurotransmitter transport GO:0006836 37 0.292
cyclic nucleotide metabolic process GO:0009187 28 0.288
circadian sleep wake cycle GO:0042745 28 0.259
neurotransmitter secretion GO:0007269 35 0.253
detection of stimulus GO:0051606 156 0.234
male courtship behavior veined wing generated song production GO:0045433 20 0.201
developmental growth GO:0048589 280 0.201
positive regulation of lyase activity GO:0051349 10 0.197
regulation of synapse organization GO:0050807 110 0.193
adult locomotory behavior GO:0008344 76 0.191
synaptic vesicle recycling GO:0036465 28 0.185
positive regulation of cgmp metabolic process GO:0030825 1 0.182
neuromuscular synaptic transmission GO:0007274 67 0.180
regulation of synapse structure and activity GO:0050803 128 0.178
positive regulation of cyclase activity GO:0031281 9 0.160
inorganic cation transmembrane transport GO:0098662 61 0.157
regulation of neurotransmitter secretion GO:0046928 14 0.157
positive regulation of purine nucleotide biosynthetic process GO:1900373 10 0.150
regulation of developmental growth GO:0048638 174 0.149
establishment of localization in cell GO:0051649 402 0.136
purine containing compound biosynthetic process GO:0072522 30 0.135
circadian rhythm GO:0007623 105 0.133
determination of adult lifespan GO:0008340 137 0.131
regulation of synapse assembly GO:0051963 94 0.130
positive regulation of multicellular organism growth GO:0040018 21 0.125
regulation of lyase activity GO:0051339 14 0.119
flight behavior GO:0007629 26 0.113
regulation of multicellular organism growth GO:0040014 40 0.112
adult behavior GO:0030534 137 0.111
positive regulation of neurotransmitter transport GO:0051590 2 0.104
circadian sleep wake cycle sleep GO:0050802 23 0.099
carbohydrate derivative biosynthetic process GO:1901137 85 0.089
anatomical structure homeostasis GO:0060249 97 0.085
cgmp biosynthetic process GO:0006182 8 0.084
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.083
positive regulation of neurotransmitter secretion GO:0001956 2 0.082
multicellular organism growth GO:0035264 46 0.081
regulation of synaptic transmission GO:0050804 69 0.078
nucleotide metabolic process GO:0009117 161 0.077
vesicle mediated transport GO:0016192 381 0.075
synaptic vesicle localization GO:0097479 53 0.075
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 9 0.072
developmental maturation GO:0021700 172 0.071
multicellular organismal aging GO:0010259 140 0.069
response to heat GO:0009408 63 0.069
secretion by cell GO:0032940 101 0.066
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.066
response to abiotic stimulus GO:0009628 341 0.064
positive regulation of developmental growth GO:0048639 62 0.060
establishment of organelle localization GO:0051656 122 0.059
ribose phosphate biosynthetic process GO:0046390 28 0.056
cyclic purine nucleotide metabolic process GO:0052652 25 0.055
larval locomotory behavior GO:0008345 27 0.055
regulation of circadian rhythm GO:0042752 49 0.054
inositol lipid mediated signaling GO:0048017 4 0.053
synaptic vesicle transport GO:0048489 50 0.052
dna packaging GO:0006323 91 0.052
secretion GO:0046903 109 0.050
larval feeding behavior GO:0030536 15 0.050
regulation of guanylate cyclase activity GO:0031282 1 0.049
purine ribonucleotide biosynthetic process GO:0009152 28 0.048
synapse assembly GO:0007416 143 0.048
calcium ion transmembrane transport GO:0070588 17 0.048
vesicle localization GO:0051648 55 0.047
axonogenesis GO:0007409 290 0.047
developmental cell growth GO:0048588 52 0.047
synaptic vesicle endocytosis GO:0048488 28 0.047
cellular macromolecule localization GO:0070727 220 0.045
regulation of nervous system development GO:0051960 248 0.044
regulation of cellular localization GO:0060341 136 0.044
exocytosis GO:0006887 28 0.044
synapse organization GO:0050808 196 0.044
chromatin assembly GO:0031497 48 0.043
nucleoside phosphate metabolic process GO:0006753 162 0.042
detection of light stimulus GO:0009583 58 0.042
protein localization GO:0008104 284 0.042
chemosensory behavior GO:0007635 106 0.040
regulation of behavior GO:0050795 75 0.038
ion transmembrane transport GO:0034220 122 0.038
organelle localization GO:0051640 148 0.038
nucleus organization GO:0006997 45 0.038
regulation of nucleotide biosynthetic process GO:0030808 14 0.037
organonitrogen compound biosynthetic process GO:1901566 117 0.037
sensory organ morphogenesis GO:0090596 260 0.036
single organism cellular localization GO:1902580 180 0.035
organonitrogen compound metabolic process GO:1901564 318 0.034
regulation of neurotransmitter transport GO:0051588 14 0.034
aging GO:0007568 143 0.034
adult walking behavior GO:0007628 9 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
positive regulation of growth GO:0045927 75 0.032
protein localization to nucleus GO:0034504 55 0.032
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.030
aromatic amino acid family metabolic process GO:0009072 3 0.029
anesthesia resistant memory GO:0007615 6 0.029
positive regulation of exocytosis GO:0045921 4 0.029
response to radiation GO:0009314 155 0.029
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.028
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
molting cycle chitin based cuticle GO:0007591 56 0.028
single organism intracellular transport GO:1902582 207 0.028
cellular response to endogenous stimulus GO:0071495 80 0.027
regulation of synaptic vesicle exocytosis GO:2000300 3 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
regulation of synaptic activity GO:0060025 9 0.027
axon development GO:0061564 297 0.026
neuromuscular process GO:0050905 21 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
cell proliferation GO:0008283 299 0.026
lipid homeostasis GO:0055088 33 0.026
detection of external stimulus GO:0009581 66 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
mrna processing GO:0006397 104 0.025
signal release GO:0023061 49 0.024
tube morphogenesis GO:0035239 191 0.024
protein heterooligomerization GO:0051291 4 0.024
regulation of transport GO:0051049 181 0.024
positive regulation of nucleotide biosynthetic process GO:0030810 10 0.023
carbohydrate utilization GO:0009758 1 0.023
organic substance transport GO:0071702 257 0.023
transmembrane transport GO:0055085 139 0.023
regulation of circadian sleep wake cycle GO:0042749 25 0.023
ribonucleotide biosynthetic process GO:0009260 28 0.023
alternative mrna splicing via spliceosome GO:0000380 60 0.023
macromolecular complex assembly GO:0065003 256 0.023
maintenance of presynaptic active zone structure GO:0048790 8 0.022
cgmp metabolic process GO:0046068 11 0.022
response to light stimulus GO:0009416 124 0.022
compound eye photoreceptor development GO:0042051 78 0.022
spinal cord development GO:0021510 1 0.022
regulation of organ growth GO:0046620 42 0.021
small molecule metabolic process GO:0044281 305 0.021
cell growth GO:0016049 108 0.021
ribose phosphate metabolic process GO:0019693 145 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
positive regulation of synaptic vesicle recycling GO:1903423 4 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
organophosphate biosynthetic process GO:0090407 46 0.020
membrane biogenesis GO:0044091 8 0.020
neurological system process GO:0050877 358 0.020
locomotor rhythm GO:0045475 56 0.020
membrane organization GO:0061024 112 0.020
regulation of vesicle mediated transport GO:0060627 59 0.019
necrotic cell death GO:0070265 1 0.019
regulation of membrane potential GO:0042391 35 0.019
appendage development GO:0048736 401 0.019
phagocytosis GO:0006909 215 0.019
regulation of secretion by cell GO:1903530 39 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.019
insulin receptor signaling pathway GO:0008286 25 0.019
regulation of glutamate receptor signaling pathway GO:1900449 1 0.019
cortical cytoskeleton organization GO:0030865 29 0.019
rna splicing GO:0008380 83 0.018
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.018
cytoskeleton dependent cytokinesis GO:0061640 81 0.018
regulation of exocytosis GO:0017157 6 0.018
chromosome segregation GO:0007059 157 0.018
rna splicing via transesterification reactions GO:0000375 73 0.018
sensory perception GO:0007600 196 0.018
ribonucleoside monophosphate catabolic process GO:0009158 39 0.017
detection of stimulus involved in sensory perception GO:0050906 92 0.017
positive regulation of synaptic transmission GO:0050806 15 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
organelle assembly GO:0070925 198 0.017
dna conformation change GO:0071103 105 0.017
protein import into nucleus GO:0006606 51 0.016
female mating behavior GO:0060180 30 0.016
negative regulation of response to oxidative stress GO:1902883 1 0.016
sleep GO:0030431 49 0.016
primary amino compound biosynthetic process GO:1901162 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
molting cycle GO:0042303 56 0.016
cellular response to chemical stimulus GO:0070887 199 0.015
phosphatidylinositol mediated signaling GO:0048015 4 0.015
cellular protein localization GO:0034613 160 0.015
regulation of necrotic cell death GO:0010939 1 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
regionalization GO:0003002 416 0.015
single organism membrane organization GO:0044802 93 0.015
positive regulation of secretion GO:0051047 22 0.015
protein complex biogenesis GO:0070271 201 0.015
neuron projection extension GO:1990138 32 0.015
compound eye development GO:0048749 307 0.015
triglyceride homeostasis GO:0070328 18 0.015
response to temperature stimulus GO:0009266 106 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.014
eye morphogenesis GO:0048592 260 0.014
regulation of membrane depolarization GO:0003254 1 0.014
determination of bilateral symmetry GO:0009855 13 0.014
regulation of protein complex disassembly GO:0043244 29 0.014
positive regulation of signal transduction GO:0009967 223 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
sensory perception of sound GO:0007605 56 0.014
intracellular protein transport GO:0006886 104 0.014
larval development GO:0002164 104 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
positive regulation of synapse assembly GO:0051965 29 0.013
endocytosis GO:0006897 310 0.013
action potential GO:0001508 13 0.013
purine containing compound metabolic process GO:0072521 155 0.013
circadian sleep wake cycle process GO:0022410 24 0.013
protein targeting to nucleus GO:0044744 51 0.013
synaptic transmission glutamatergic GO:0035249 7 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
regulation of localization GO:0032879 275 0.013
detection of abiotic stimulus GO:0009582 66 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
regulation of growth rate GO:0040009 3 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
chromatin assembly or disassembly GO:0006333 52 0.012
appendage morphogenesis GO:0035107 397 0.012
regulation of cellular response to oxidative stress GO:1900407 4 0.012
mitotic chromosome condensation GO:0007076 22 0.012
embryonic morphogenesis GO:0048598 206 0.012
purine nucleotide biosynthetic process GO:0006164 29 0.012
positive regulation of transport GO:0051050 92 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
regulation of response to oxidative stress GO:1902882 4 0.012
positive regulation of developmental process GO:0051094 143 0.012
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.012
rhythmic synaptic transmission GO:0060024 2 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
acid secretion GO:0046717 1 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
regulation of secretion GO:0051046 44 0.011
nucleotide biosynthetic process GO:0009165 34 0.011
regulation of cell proliferation GO:0042127 163 0.011
spindle organization GO:0007051 253 0.011
protein transport GO:0015031 155 0.011
regulation of neuron differentiation GO:0045664 103 0.011
indole containing compound biosynthetic process GO:0042435 4 0.011
sister chromatid segregation GO:0000819 92 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.011
developmental growth involved in morphogenesis GO:0060560 65 0.011
regulation of mrna processing GO:0050684 71 0.011
negative regulation of cellular response to oxidative stress GO:1900408 1 0.011
regulation of cell projection organization GO:0031344 92 0.011
synaptic vesicle exocytosis GO:0016079 16 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
immune system process GO:0002376 347 0.010
muscle tissue morphogenesis GO:0060415 2 0.010
negative regulation of hormone biosynthetic process GO:0032353 1 0.010
mrna metabolic process GO:0016071 124 0.010
spindle localization GO:0051653 22 0.010
positive regulation of cgmp biosynthetic process GO:0030828 1 0.010
carboxylic acid metabolic process GO:0019752 92 0.010
establishment of vesicle localization GO:0051650 51 0.010
regulation of cellular component size GO:0032535 98 0.010
axon extension GO:0048675 32 0.010

Vmat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.037
disease of anatomical entity DOID:7 0 0.037
musculoskeletal system disease DOID:17 0 0.037
muscle tissue disease DOID:66 0 0.023
myopathy DOID:423 0 0.018
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
cardiovascular system disease DOID:1287 0 0.018
neuromuscular disease DOID:440 0 0.010
nervous system disease DOID:863 0 0.010
neuropathy DOID:870 0 0.010