Drosophila melanogaster

0 known processes

Lip3 (Dmel_CG8823)

CG8823 gene product from transcript CG8823-RA

(Aliases: Dmlip3,LIP3,Dmel\CG8823,dLip3,lip3,LIP3Dm,CG8823)

Lip3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.210
pigment metabolic process GO:0042440 84 0.169
response to external biotic stimulus GO:0043207 293 0.127
Worm
defense response GO:0006952 300 0.119
Worm
positive regulation of melanization defense response GO:0035008 1 0.116
vesicle mediated transport GO:0016192 381 0.114
response to other organism GO:0051707 293 0.113
Worm
response to biotic stimulus GO:0009607 294 0.097
Worm
defense response to bacterium GO:0042742 178 0.082
Worm
organic hydroxy compound metabolic process GO:1901615 83 0.080
Yeast Rat
secondary metabolic process GO:0019748 75 0.077
regulation of production of molecular mediator of immune response GO:0002700 44 0.073
imaginal disc derived appendage development GO:0048737 399 0.072
response to extracellular stimulus GO:0009991 116 0.072
Worm
sterol homeostasis GO:0055092 4 0.071
Fly
small molecule metabolic process GO:0044281 305 0.067
Yeast Rat
phagocytosis GO:0006909 215 0.066
imaginal disc derived appendage morphogenesis GO:0035114 395 0.063
immune system process GO:0002376 347 0.060
endocytosis GO:0006897 310 0.058
death GO:0016265 284 0.057
homeostatic process GO:0042592 199 0.055
Fly
response to copper ion GO:0046688 4 0.053
post embryonic appendage morphogenesis GO:0035120 385 0.053
regulation of defense response GO:0031347 102 0.052
phenol containing compound metabolic process GO:0018958 57 0.051
negative regulation of signaling GO:0023057 219 0.050
regulation of humoral immune response GO:0002920 51 0.050
oxoacid metabolic process GO:0043436 103 0.050
Rat
organonitrogen compound biosynthetic process GO:1901566 117 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
appendage development GO:0048736 401 0.047
cholesterol homeostasis GO:0042632 3 0.047
Fly
regionalization GO:0003002 416 0.047
ethanolamine containing compound metabolic process GO:0042439 4 0.046
innate immune response GO:0045087 144 0.045
immune effector process GO:0002252 98 0.045
peptide metabolic process GO:0006518 80 0.045
response to lipopolysaccharide GO:0032496 4 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
organic substance catabolic process GO:1901575 308 0.042
Worm
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.042
regulation of response to stress GO:0080134 200 0.042
Worm
production of molecular mediator of immune response GO:0002440 46 0.041
acylglycerol catabolic process GO:0046464 3 0.041
Worm
response to nutrient levels GO:0031667 114 0.041
Worm
axis specification GO:0009798 167 0.040
peptide biosynthetic process GO:0043043 42 0.040
positive regulation of antimicrobial peptide production GO:0002225 28 0.040
catabolic process GO:0009056 409 0.040
Worm
regulation of antimicrobial peptide production GO:0002784 44 0.039
wing disc morphogenesis GO:0007472 344 0.039
response to oxygen containing compound GO:1901700 200 0.039
carboxylic acid metabolic process GO:0019752 92 0.038
Rat
benzene containing compound metabolic process GO:0042537 3 0.038
dorsal ventral pattern formation GO:0009953 133 0.037
lateral inhibition GO:0046331 206 0.035
appendage morphogenesis GO:0035107 397 0.035
cell death GO:0008219 279 0.034
estrogen metabolic process GO:0008210 1 0.033
xenobiotic catabolic process GO:0042178 1 0.033
ovarian follicle cell development GO:0030707 248 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
regulation of antimicrobial humoral response GO:0002759 50 0.032
epithelial cell migration GO:0010631 148 0.032
steroid catabolic process GO:0006706 1 0.032
single organism catabolic process GO:0044712 228 0.032
Worm
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
antibacterial peptide biosynthetic process GO:0002780 22 0.032
negative regulation of cell communication GO:0010648 223 0.032
immune response GO:0006955 246 0.031
response to organic substance GO:0010033 284 0.031
pigment biosynthetic process GO:0046148 36 0.031
anion homeostasis GO:0055081 3 0.031
positive regulation of signal transduction GO:0009967 223 0.031
growth GO:0040007 359 0.030
gland development GO:0048732 191 0.030
response to abiotic stimulus GO:0009628 341 0.030
positive regulation of immune effector process GO:0002699 28 0.030
negative regulation of signal transduction GO:0009968 206 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
cellular amide metabolic process GO:0043603 80 0.029
ameboidal type cell migration GO:0001667 151 0.029
regulation of immune system process GO:0002682 176 0.029
positive regulation of response to stimulus GO:0048584 323 0.028
Worm
body morphogenesis GO:0010171 2 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.027
regulation of sequestering of triglyceride GO:0010889 3 0.027
organic acid metabolic process GO:0006082 103 0.027
Rat
protein modification process GO:0036211 438 0.027
multi organism behavior GO:0051705 175 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
androgen metabolic process GO:0008209 1 0.026
tissue migration GO:0090130 155 0.026
epithelium migration GO:0090132 148 0.026
regulation of immune response GO:0050776 118 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
leg disc development GO:0035218 92 0.026
monocarboxylic acid transport GO:0015718 3 0.025
cholesterol transport GO:0030301 2 0.025
sensory perception of chemical stimulus GO:0007606 116 0.025
triglyceride biosynthetic process GO:0019432 2 0.025
hormone catabolic process GO:0042447 3 0.025
cellular amine metabolic process GO:0044106 12 0.025
regulation of notch signaling pathway GO:0008593 100 0.025
regulation of innate immune response GO:0045088 71 0.024
positive regulation of lipid storage GO:0010884 4 0.024
response to radiation GO:0009314 155 0.024
regulation of programmed cell death GO:0043067 152 0.024
organic substance transport GO:0071702 257 0.024
dorsal ventral axis specification GO:0009950 66 0.023
regulation of cellular amide metabolic process GO:0034248 39 0.023
phospholipid homeostasis GO:0055091 1 0.023
open tracheal system development GO:0007424 204 0.023
regulation of transport GO:0051049 181 0.023
toll signaling pathway GO:0008063 25 0.022
zymogen activation GO:0031638 20 0.022
melanization defense response GO:0035006 45 0.022
amide biosynthetic process GO:0043604 42 0.022
respiratory system development GO:0060541 213 0.022
lipid metabolic process GO:0006629 121 0.022
Yeast Rat Worm
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.022
notch signaling pathway GO:0007219 120 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
humoral immune response GO:0006959 117 0.021
phosphorylation GO:0016310 294 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
positive regulation of cell communication GO:0010647 250 0.021
Worm
melanin metabolic process GO:0006582 47 0.021
regulation of sterol transport GO:0032371 1 0.021
regulation of response to external stimulus GO:0032101 115 0.021
Worm
protein complex assembly GO:0006461 200 0.021
organophosphate metabolic process GO:0019637 195 0.021
protein complex biogenesis GO:0070271 201 0.021
inter male aggressive behavior GO:0002121 60 0.020
programmed cell death GO:0012501 257 0.020
positive regulation of signaling GO:0023056 243 0.020
lipid homeostasis GO:0055088 33 0.020
Fly
protein hydroxylation GO:0018126 1 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
regulation of response to biotic stimulus GO:0002831 63 0.020
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.020
acylglycerol biosynthetic process GO:0046463 2 0.020
establishment of localization in cell GO:0051649 402 0.020
triglyceride catabolic process GO:0019433 3 0.020
Worm
macromolecular complex assembly GO:0065003 256 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
response to light stimulus GO:0009416 124 0.020
amine metabolic process GO:0009308 12 0.020
cellular response to organic substance GO:0071310 132 0.020
cell division GO:0051301 248 0.020
positive regulation of response to biotic stimulus GO:0002833 31 0.020
neutral lipid biosynthetic process GO:0046460 2 0.020
regulation of defense response to bacterium GO:1900424 30 0.020
response to starvation GO:0042594 97 0.020
Worm
phosphatidic acid metabolic process GO:0046473 1 0.020
eye development GO:0001654 323 0.019
alditol phosphate metabolic process GO:0052646 2 0.019
positive regulation of cellular amide metabolic process GO:0034250 26 0.019
neurological system process GO:0050877 358 0.019
single organism behavior GO:0044708 391 0.019
regulation of anatomical structure size GO:0090066 163 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
positive regulation of humoral immune response GO:0002922 28 0.019
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
glycerolipid catabolic process GO:0046503 3 0.018
Worm
pigment metabolic process involved in pigmentation GO:0043474 33 0.018
phosphatidylethanolamine metabolic process GO:0046337 1 0.018
single organism biosynthetic process GO:0044711 206 0.018
response to fungus GO:0009620 50 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
taxis GO:0042330 304 0.017
wound healing GO:0042060 75 0.017
cytoplasmic transport GO:0016482 130 0.017
anatomical structure homeostasis GO:0060249 97 0.017
negative regulation of developmental process GO:0051093 201 0.017
sensory perception of smell GO:0007608 80 0.017
mating GO:0007618 120 0.017
positive regulation of sequestering of triglyceride GO:0010890 1 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
defense response to fungus GO:0050832 48 0.017
developmental pigmentation GO:0048066 68 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
regulation of localization GO:0032879 275 0.017
regulation of multi organism process GO:0043900 131 0.017
purine containing compound metabolic process GO:0072521 155 0.017
determination of adult lifespan GO:0008340 137 0.017
Worm
compound eye development GO:0048749 307 0.017
germarium derived egg chamber formation GO:0007293 101 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
response to organic cyclic compound GO:0014070 89 0.017
cell proliferation GO:0008283 299 0.017
secondary metabolite biosynthetic process GO:0044550 24 0.017
response to temperature stimulus GO:0009266 106 0.016
response to nitrogen compound GO:1901698 90 0.016
positive regulation of multi organism process GO:0043902 40 0.016
neuron projection guidance GO:0097485 241 0.016
chemotaxis GO:0006935 249 0.016
positive regulation of antibacterial peptide production GO:0002803 20 0.016
cell migration GO:0016477 238 0.016
response to organophosphorus GO:0046683 2 0.016
exocrine system development GO:0035272 162 0.016
rna splicing GO:0008380 83 0.016
antimicrobial peptide biosynthetic process GO:0002777 38 0.016
proteolysis GO:0006508 192 0.016
acetylcholine metabolic process GO:0008291 2 0.016
epithelial cell development GO:0002064 274 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
response to metal ion GO:0010038 23 0.016
spindle organization GO:0007051 253 0.015
endomembrane system organization GO:0010256 119 0.015
kidney development GO:0001822 3 0.015
axon guidance GO:0007411 233 0.015
camera type eye development GO:0043010 4 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
organophosphate catabolic process GO:0046434 112 0.015
aggressive behavior GO:0002118 63 0.015
regulation of antibacterial peptide production GO:0002786 22 0.015
cellular macromolecule localization GO:0070727 220 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
male mating behavior GO:0060179 70 0.015
nucleoside metabolic process GO:0009116 127 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
developmental maturation GO:0021700 172 0.015
heterocycle catabolic process GO:0046700 166 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
regulation of catalytic activity GO:0050790 185 0.015
biological adhesion GO:0022610 138 0.015
cellular catabolic process GO:0044248 372 0.015
Worm
mating behavior GO:0007617 106 0.015
neurotransmitter metabolic process GO:0042133 2 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
regulation of cholesterol transport GO:0032374 1 0.014
rna processing GO:0006396 147 0.014
organelle assembly GO:0070925 198 0.014
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.014
carbohydrate metabolic process GO:0005975 82 0.014
eye pigment metabolic process GO:0042441 33 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
regulation of cell death GO:0010941 173 0.014
response to bacterium GO:0009617 198 0.014
Worm
defense response to other organism GO:0098542 225 0.014
Worm
small gtpase mediated signal transduction GO:0007264 88 0.014
maintenance of location GO:0051235 73 0.014
Worm
actin filament based process GO:0030029 220 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
actin filament organization GO:0007015 126 0.014
epithelial cell differentiation GO:0030855 322 0.014
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.014
aromatic compound catabolic process GO:0019439 166 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
peripheral nervous system development GO:0007422 52 0.014
connective tissue development GO:0061448 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of growth GO:0040008 233 0.014
chaeta development GO:0022416 97 0.014
cell motility GO:0048870 251 0.013
purine containing compound catabolic process GO:0072523 112 0.013
response to inorganic substance GO:0010035 44 0.013
regulation of toll signaling pathway GO:0008592 17 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
leg disc morphogenesis GO:0007478 80 0.013
pigmentation GO:0043473 75 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
cellular protein catabolic process GO:0044257 83 0.013
cellular protein modification process GO:0006464 438 0.013
organelle fusion GO:0048284 46 0.013
response to organonitrogen compound GO:0010243 75 0.013
positive regulation of cell migration GO:0030335 2 0.013
ion transport GO:0006811 145 0.013
response to alcohol GO:0097305 95 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
dorsal closure GO:0007391 79 0.013
segmentation GO:0035282 207 0.013
synaptic transmission GO:0007268 288 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
peptidyl proline hydroxylation GO:0019511 1 0.013
courtship behavior GO:0007619 68 0.013
cellular response to dna damage stimulus GO:0006974 223 0.012
chorion containing eggshell formation GO:0007304 105 0.012
multicellular organismal aging GO:0010259 140 0.012
Worm
regulation of mrna processing GO:0050684 71 0.012
single organism intracellular transport GO:1902582 207 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
border follicle cell migration GO:0007298 113 0.012
ocellus pigment biosynthetic process GO:0008055 19 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
chemical homeostasis GO:0048878 92 0.012
Fly
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
protein transport GO:0015031 155 0.012
somatic muscle development GO:0007525 66 0.012
protein maturation GO:0051604 71 0.012
acetate ester metabolic process GO:1900619 2 0.012
steroid metabolic process GO:0008202 20 0.012
Yeast Rat
protein processing GO:0016485 68 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
response to wounding GO:0009611 94 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
positive regulation of immune system process GO:0002684 68 0.012
cellular response to ethanol GO:0071361 4 0.012
ovarian follicle cell migration GO:0007297 121 0.012
establishment of protein localization GO:0045184 163 0.012
telencephalon development GO:0021537 2 0.012
alternative mrna splicing via spliceosome GO:0000380 60 0.012
eye pigment biosynthetic process GO:0006726 32 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
peptidyl amino acid modification GO:0018193 105 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
histolysis GO:0007559 102 0.011
regulation of tube size open tracheal system GO:0035151 43 0.011
sulfur compound metabolic process GO:0006790 59 0.011
intracellular transport GO:0046907 228 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of developmental growth GO:0048638 174 0.011
nucleotide metabolic process GO:0009117 161 0.011
localization of cell GO:0051674 257 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
positive regulation of immune response GO:0050778 63 0.011
ras protein signal transduction GO:0007265 88 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.011
response to endogenous stimulus GO:0009719 119 0.011
cell adhesion GO:0007155 136 0.011
negative regulation of growth GO:0045926 84 0.011
compound eye morphogenesis GO:0001745 249 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
response to monosaccharide GO:0034284 4 0.011
lipid storage GO:0019915 38 0.011
Worm
apoptotic process GO:0006915 159 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
sensory perception GO:0007600 196 0.011
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
salivary gland morphogenesis GO:0007435 145 0.011
autophagic cell death GO:0048102 83 0.011
response to glucose GO:0009749 2 0.011
multi multicellular organism process GO:0044706 123 0.011
phosphatidylcholine metabolic process GO:0046470 3 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
gtp metabolic process GO:0046039 72 0.011
cellular modified amino acid metabolic process GO:0006575 45 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of molecular function GO:0044093 136 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
peptidyl proline modification GO:0018208 3 0.010
regulation of rna splicing GO:0043484 69 0.010
sensory perception of pain GO:0019233 4 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
carboxylic acid transport GO:0046942 18 0.010
response to oxidative stress GO:0006979 86 0.010
medium chain fatty acid metabolic process GO:0051791 1 0.010
cellular protein localization GO:0034613 160 0.010
forebrain development GO:0030900 2 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
positive regulation of gene expression GO:0010628 290 0.010
response to hexose GO:0009746 3 0.010
vesicle organization GO:0016050 44 0.010
cellular ketone metabolic process GO:0042180 24 0.010
cell cell junction organization GO:0045216 55 0.010
peptidyl tyrosine modification GO:0018212 24 0.010
behavioral response to pain GO:0048266 3 0.010
antimicrobial humoral response GO:0019730 99 0.010
lipid localization GO:0010876 54 0.010
Worm
salivary gland histolysis GO:0035070 88 0.010
regulation of molecular function GO:0065009 217 0.010

Lip3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
disease of metabolism DOID:0014667 0 0.037
inherited metabolic disorder DOID:655 0 0.034
lipid metabolism disorder DOID:3146 0 0.030
nervous system disease DOID:863 0 0.021
familial hyperlipidemia DOID:1168 0 0.019
familial combined hyperlipidemia DOID:13809 0 0.019
diabetes mellitus DOID:9351 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.017
glucose metabolism disease DOID:4194 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
familial hypertriglyceridemia DOID:0050527 0 0.015
hair disease DOID:421 0 0.015
integumentary system disease DOID:16 0 0.015
hypotrichosis DOID:4535 0 0.015
cardiovascular system disease DOID:1287 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
renal tubular transport disease DOID:447 0 0.014
kidney disease DOID:557 0 0.014
urinary system disease DOID:18 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
familial lipoprotein lipase deficiency DOID:14118 0 0.011
sensory system disease DOID:0050155 0 0.010