Drosophila melanogaster

79 known processes

vis (Dmel_CG8821)

vismay

(Aliases: TGIFa,zaa,Dmel\CG8821,achi/vis,dTGIFa,CG8821)

vis biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.140
transcription from rna polymerase ii promoter GO:0006366 368 0.120
positive regulation of macromolecule metabolic process GO:0010604 405 0.118
positive regulation of cellular biosynthetic process GO:0031328 316 0.115
positive regulation of rna biosynthetic process GO:1902680 266 0.102
spermatogenesis GO:0007283 200 0.100
positive regulation of gene expression GO:0010628 290 0.096
positive regulation of rna metabolic process GO:0051254 271 0.090
cell cell signaling involved in cell fate commitment GO:0045168 210 0.089
negative regulation of rna metabolic process GO:0051253 251 0.083
Human Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.077
positive regulation of nucleic acid templated transcription GO:1903508 266 0.076
lateral inhibition GO:0046331 206 0.074
cellularization GO:0007349 90 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.069
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
Human Yeast
positive regulation of biosynthetic process GO:0009891 316 0.065
camera type eye development GO:0043010 4 0.062
regionalization GO:0003002 416 0.060
eye development GO:0001654 323 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.059
Human Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
Human Yeast
cell division GO:0051301 248 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.052
negative regulation of signaling GO:0023057 219 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.051
Human Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.050
Human Yeast
negative regulation of cell communication GO:0010648 223 0.050
regulation of multicellular organismal development GO:2000026 414 0.049
negative regulation of rna biosynthetic process GO:1902679 240 0.049
Human Yeast
negative regulation of signal transduction GO:0009968 206 0.048
negative regulation of transcription dna templated GO:0045892 237 0.047
Human Yeast
regulation of nervous system development GO:0051960 248 0.046
response to organic substance GO:0010033 284 0.045
Rat
male gamete generation GO:0048232 201 0.045
negative regulation of response to stimulus GO:0048585 258 0.044
regulation of localization GO:0032879 275 0.041
Yeast
dorsal ventral pattern formation GO:0009953 133 0.041
spermatid differentiation GO:0048515 114 0.040
catabolic process GO:0009056 409 0.040
small molecule metabolic process GO:0044281 305 0.038
regulation of embryonic development GO:0045995 68 0.038
enzyme linked receptor protein signaling pathway GO:0007167 179 0.037
cellular response to dna damage stimulus GO:0006974 223 0.036
cellular catabolic process GO:0044248 372 0.035
organic substance transport GO:0071702 257 0.035
Yeast
cell projection assembly GO:0030031 94 0.033
cell proliferation GO:0008283 299 0.033
cellular component assembly involved in morphogenesis GO:0010927 151 0.033
appendage development GO:0048736 401 0.032
organonitrogen compound metabolic process GO:1901564 318 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.030
Human Yeast
regulation of cell development GO:0060284 215 0.030
retina development in camera type eye GO:0060041 4 0.030
maintenance of location GO:0051235 73 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
cellular response to chemical stimulus GO:0070887 199 0.029
Rat
organic substance catabolic process GO:1901575 308 0.029
regulation of cell differentiation GO:0045595 302 0.029
death GO:0016265 284 0.028
cellular protein modification process GO:0006464 438 0.027
response to abiotic stimulus GO:0009628 341 0.027
vesicle mediated transport GO:0016192 381 0.027
regulation of neuron differentiation GO:0045664 103 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
response to radiation GO:0009314 155 0.026
organelle fission GO:0048285 340 0.026
regulation of cell division GO:0051302 72 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
wing disc morphogenesis GO:0007472 344 0.026
protein modification process GO:0036211 438 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
protein localization GO:0008104 284 0.024
regulation of neurogenesis GO:0050767 158 0.024
appendage morphogenesis GO:0035107 397 0.024
regulation of cell cycle phase transition GO:1901987 130 0.024
cell death GO:0008219 279 0.024
cilium organization GO:0044782 41 0.024
organic acid metabolic process GO:0006082 103 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
forebrain development GO:0030900 2 0.023
organelle assembly GO:0070925 198 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
tube development GO:0035295 244 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
cellular macromolecule catabolic process GO:0044265 136 0.022
macromolecular complex assembly GO:0065003 256 0.022
lipid storage GO:0019915 38 0.022
regulation of protein metabolic process GO:0051246 256 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
regulation of transport GO:0051049 181 0.022
Yeast
regulation of cell proliferation GO:0042127 163 0.021
single organism catabolic process GO:0044712 228 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
cellular response to organic substance GO:0071310 132 0.021
Rat
tube morphogenesis GO:0035239 191 0.021
compound eye development GO:0048749 307 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
nitrogen compound transport GO:0071705 85 0.021
Yeast
phosphorylation GO:0016310 294 0.021
cellular response to abiotic stimulus GO:0071214 58 0.021
taxis GO:0042330 304 0.021
proteolysis GO:0006508 192 0.021
regulation of cell cycle GO:0051726 291 0.021
digestive tract development GO:0048565 149 0.021
phagocytosis GO:0006909 215 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
cell cycle phase transition GO:0044770 140 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
body morphogenesis GO:0010171 2 0.019
endocytosis GO:0006897 310 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
programmed cell death GO:0012501 257 0.019
macromolecule catabolic process GO:0009057 161 0.019
establishment of localization in cell GO:0051649 402 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
Human Yeast
segmentation GO:0035282 207 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
response to other organism GO:0051707 293 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
lipid localization GO:0010876 54 0.018
single organism biosynthetic process GO:0044711 206 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
regulation of response to stress GO:0080134 200 0.018
dendrite development GO:0016358 204 0.018
heterocycle catabolic process GO:0046700 166 0.018
epithelial cell differentiation GO:0030855 322 0.018
regulation of phosphorylation GO:0042325 147 0.018
epithelial cell development GO:0002064 274 0.017
response to lipopolysaccharide GO:0032496 4 0.017
protein complex assembly GO:0006461 200 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
mitotic dna damage checkpoint GO:0044773 74 0.017
chromosome organization GO:0051276 360 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
axon development GO:0061564 297 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
positive regulation of neurogenesis GO:0050769 41 0.017
telencephalon development GO:0021537 2 0.017
regulation of catabolic process GO:0009894 170 0.017
compound eye morphogenesis GO:0001745 249 0.017
positive regulation of cell communication GO:0010647 250 0.017
purine containing compound metabolic process GO:0072521 155 0.017
negative regulation of gene expression GO:0010629 387 0.017
Human Yeast Rat
regulation of cellular amine metabolic process GO:0033238 3 0.017
regulation of cell cycle process GO:0010564 181 0.017
intracellular transport GO:0046907 228 0.017
organophosphate metabolic process GO:0019637 195 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
positive regulation of cell differentiation GO:0045597 64 0.017
chemotaxis GO:0006935 249 0.016
homeostatic process GO:0042592 199 0.016
detection of stimulus GO:0051606 156 0.016
digestive system development GO:0055123 149 0.016
developmental maturation GO:0021700 172 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
kidney development GO:0001822 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
gastrulation GO:0007369 70 0.016
sperm individualization GO:0007291 48 0.016
g protein coupled receptor signaling pathway GO:0007186 136 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
intracellular signal transduction GO:0035556 300 0.016
regulation of catalytic activity GO:0050790 185 0.016
aromatic compound catabolic process GO:0019439 166 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
protein phosphorylation GO:0006468 169 0.016
cellular protein catabolic process GO:0044257 83 0.016
cellular ketone metabolic process GO:0042180 24 0.016
exocrine system development GO:0035272 162 0.016
mrna metabolic process GO:0016071 124 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
microtubule organizing center organization GO:0031023 168 0.015
regulation of molecular function GO:0065009 217 0.015
response to external biotic stimulus GO:0043207 293 0.015
protein catabolic process GO:0030163 101 0.015
localization of cell GO:0051674 257 0.015
dna integrity checkpoint GO:0031570 81 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
acyl coa metabolic process GO:0006637 3 0.015
central nervous system development GO:0007417 201 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
nucleotide metabolic process GO:0009117 161 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
response to glucose GO:0009749 2 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
regulation of anatomical structure size GO:0090066 163 0.015
protein dna complex subunit organization GO:0071824 86 0.015
cellular response to growth factor stimulus GO:0071363 30 0.014
Rat
small gtpase mediated signal transduction GO:0007264 88 0.014
positive regulation of cell development GO:0010720 61 0.014
defense response to other organism GO:0098542 225 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
ras protein signal transduction GO:0007265 88 0.014
single organism intracellular transport GO:1902582 207 0.014
nuclear division GO:0000280 332 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of organelle organization GO:0033043 196 0.014
positive regulation of nervous system development GO:0051962 69 0.014
spermatid development GO:0007286 98 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
positive regulation of cell motility GO:2000147 3 0.014
actin filament based process GO:0030029 220 0.014
connective tissue development GO:0061448 3 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
positive regulation of developmental process GO:0051094 143 0.014
axon guidance GO:0007411 233 0.014
developmental programmed cell death GO:0010623 138 0.014
eye morphogenesis GO:0048592 260 0.014
blastoderm segmentation GO:0007350 159 0.014
response to biotic stimulus GO:0009607 294 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
mitotic nuclear division GO:0007067 213 0.014
nucleoside metabolic process GO:0009116 127 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
response to hexose GO:0009746 3 0.014
response to oxygen containing compound GO:1901700 200 0.014
limb development GO:0060173 1 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
negative regulation of cell cycle process GO:0010948 109 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
tissue morphogenesis GO:0048729 297 0.013
cell motility GO:0048870 251 0.013
protein complex biogenesis GO:0070271 201 0.013
purine containing compound catabolic process GO:0072523 112 0.013
cilium morphogenesis GO:0060271 39 0.013
response to light stimulus GO:0009416 124 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
positive regulation of signal transduction GO:0009967 223 0.013
immune system process GO:0002376 347 0.013
defense response to bacterium GO:0042742 178 0.013
limb morphogenesis GO:0035108 1 0.013
salivary gland development GO:0007431 162 0.013
cell maturation GO:0048469 144 0.013
single organism cellular localization GO:1902580 180 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
tripartite regional subdivision GO:0007351 103 0.013
positive regulation of signaling GO:0023056 243 0.013
cellular protein complex assembly GO:0043623 71 0.013
regulation of immune response GO:0050776 118 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
cell cycle checkpoint GO:0000075 95 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
ovarian follicle cell development GO:0030707 248 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
protein transport GO:0015031 155 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
defense response GO:0006952 300 0.013
regulation of cell death GO:0010941 173 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
dendrite morphogenesis GO:0048813 199 0.012
neuron projection guidance GO:0097485 241 0.012
apoptotic process GO:0006915 159 0.012
innate immune response GO:0045087 144 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
chromosome segregation GO:0007059 157 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
centrosome organization GO:0051297 163 0.012
amine metabolic process GO:0009308 12 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
regulation of apoptotic process GO:0042981 130 0.012
salivary gland morphogenesis GO:0007435 145 0.012
cell fate determination GO:0001709 91 0.012
organophosphate catabolic process GO:0046434 112 0.012
gland development GO:0048732 191 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
regulation of immune system process GO:0002682 176 0.012
negative regulation of developmental process GO:0051093 201 0.012
axis specification GO:0009798 167 0.012
cell migration GO:0016477 238 0.012
chaeta development GO:0022416 97 0.012
growth GO:0040007 359 0.012
head development GO:0060322 135 0.012
regulation of cellular response to stress GO:0080135 89 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of programmed cell death GO:0043067 152 0.012
positive regulation of molecular function GO:0044093 136 0.012
actin filament organization GO:0007015 126 0.012
chaeta morphogenesis GO:0008407 42 0.012
response to organophosphorus GO:0046683 2 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
cytoplasmic transport GO:0016482 130 0.011
embryonic pattern specification GO:0009880 174 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
response to monosaccharide GO:0034284 4 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
cellular protein localization GO:0034613 160 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
vitamin metabolic process GO:0006766 2 0.011
cellular amine metabolic process GO:0044106 12 0.011
embryonic axis specification GO:0000578 107 0.011
ion transport GO:0006811 145 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
mitotic spindle organization GO:0007052 220 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
sterol homeostasis GO:0055092 4 0.011
response to extracellular stimulus GO:0009991 116 0.011
dna damage checkpoint GO:0000077 78 0.011
endomembrane system organization GO:0010256 119 0.011
negative regulation of cell cycle GO:0045786 116 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
rna localization GO:0006403 115 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
chromatin modification GO:0016568 147 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of proteolysis GO:0030162 87 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
developmental growth GO:0048589 280 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
response to starvation GO:0042594 97 0.011
sensory organ morphogenesis GO:0090596 260 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
monocarboxylic acid transport GO:0015718 3 0.011
immune response activating signal transduction GO:0002757 2 0.011
nucleotide catabolic process GO:0009166 109 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
gene silencing GO:0016458 138 0.011
regulation of rna splicing GO:0043484 69 0.011
regulation of cellular component size GO:0032535 98 0.010
establishment of protein localization GO:0045184 163 0.010
wnt signaling pathway GO:0016055 98 0.010
response to nutrient levels GO:0031667 114 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
notch signaling pathway GO:0007219 120 0.010
regulation of response to external stimulus GO:0032101 115 0.010
cellular macromolecule localization GO:0070727 220 0.010
tissue death GO:0016271 102 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
response to bacterium GO:0009617 198 0.010
dorsal ventral axis specification GO:0009950 66 0.010
chromatin organization GO:0006325 207 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
hindbrain development GO:0030902 2 0.010
synapse assembly GO:0007416 143 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
actin cytoskeleton organization GO:0030036 206 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
response to endogenous stimulus GO:0009719 119 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
autophagic cell death GO:0048102 83 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
regulation of synapse organization GO:0050807 110 0.010
cellular response to radiation GO:0071478 52 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
single organism behavior GO:0044708 391 0.010
meiotic cell cycle GO:0051321 171 0.010

vis disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.020
acquired metabolic disease DOID:0060158 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.013
cardiovascular system disease DOID:1287 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
musculoskeletal system disease DOID:17 0 0.010
sensory system disease DOID:0050155 0 0.010