Drosophila melanogaster

28 known processes

inx3 (Dmel_CG1448)

innexin 3

(Aliases: Inx3,CG1448,Dm-inx3,Dmel\CG1448,inx-3,Ix3,INX-3)

inx3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 191 0.404
regionalization GO:0003002 416 0.254
epithelial cell differentiation GO:0030855 322 0.167
digestive system development GO:0055123 149 0.140
morphogenesis of an epithelium GO:0002009 276 0.139
segmentation GO:0035282 207 0.122
detection of stimulus GO:0051606 156 0.118
embryonic morphogenesis GO:0048598 206 0.114
mitotic cytokinesis GO:0000281 50 0.113
tube development GO:0035295 244 0.109
tissue morphogenesis GO:0048729 297 0.109
embryonic pattern specification GO:0009880 174 0.105
cell proliferation GO:0008283 299 0.102
blastoderm segmentation GO:0007350 159 0.102
appendage morphogenesis GO:0035107 397 0.098
Fly
regulation of anatomical structure size GO:0090066 163 0.093
axis specification GO:0009798 167 0.090
post embryonic appendage morphogenesis GO:0035120 385 0.088
Fly
dorsal ventral axis specification GO:0009950 66 0.084
response to light stimulus GO:0009416 124 0.081
digestive tract morphogenesis GO:0048546 127 0.079
cell cycle phase transition GO:0044770 140 0.078
negative regulation of cell communication GO:0010648 223 0.075
response to radiation GO:0009314 155 0.074
respiratory system development GO:0060541 213 0.074
regulation of cell differentiation GO:0045595 302 0.066
detection of light stimulus GO:0009583 58 0.065
organic substance transport GO:0071702 257 0.065
digestive tract development GO:0048565 149 0.062
wnt signaling pathway GO:0016055 98 0.059
response to organic substance GO:0010033 284 0.058
cell division GO:0051301 248 0.056
imaginal disc derived wing morphogenesis GO:0007476 337 0.056
Fly
axonogenesis GO:0007409 290 0.055
regulation of cell cycle GO:0051726 291 0.054
olfactory behavior GO:0042048 97 0.054
phototransduction visible light GO:0007603 27 0.054
establishment of localization in cell GO:0051649 402 0.054
oocyte differentiation GO:0009994 145 0.054
regulation of multicellular organismal development GO:2000026 414 0.051
organelle fission GO:0048285 340 0.051
axon guidance GO:0007411 233 0.050
cell maturation GO:0048469 144 0.050
exocrine system development GO:0035272 162 0.049
dorsal ventral pattern formation GO:0009953 133 0.048
smoothened signaling pathway GO:0007224 49 0.048
connective tissue development GO:0061448 3 0.047
wing disc morphogenesis GO:0007472 344 0.047
Fly
negative regulation of gene expression GO:0010629 387 0.047
embryonic development via the syncytial blastoderm GO:0001700 148 0.047
phototransduction GO:0007602 52 0.047
regulation of smoothened signaling pathway GO:0008589 28 0.047
single organism behavior GO:0044708 391 0.046
Fly
organic substance catabolic process GO:1901575 308 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
Fly
cell recognition GO:0008037 102 0.045
forebrain development GO:0030900 2 0.045
open tracheal system development GO:0007424 204 0.044
columnar cuboidal epithelial cell development GO:0002066 249 0.044
learning or memory GO:0007611 141 0.044
Fly
regulation of mitotic cell cycle GO:0007346 190 0.043
morphogenesis of embryonic epithelium GO:0016331 94 0.041
regulation of localization GO:0032879 275 0.040
meiotic cell cycle GO:0051321 171 0.040
detection of external stimulus GO:0009581 66 0.040
epithelial cell development GO:0002064 274 0.040
nephron development GO:0072006 3 0.039
anterior posterior axis specification embryo GO:0008595 103 0.039
oocyte development GO:0048599 124 0.039
salivary gland morphogenesis GO:0007435 145 0.039
single organism biosynthetic process GO:0044711 206 0.039
appendage development GO:0048736 401 0.038
Fly
detection of stimulus involved in sensory perception GO:0050906 92 0.038
positive regulation of transcription dna templated GO:0045893 266 0.038
negative regulation of signaling GO:0023057 219 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.037
mesenchymal cell differentiation GO:0048762 1 0.036
vesicle mediated transport GO:0016192 381 0.036
cytokinesis GO:0000910 90 0.036
central nervous system development GO:0007417 201 0.036
regulation of cell cycle process GO:0010564 181 0.036
gland morphogenesis GO:0022612 145 0.036
organonitrogen compound metabolic process GO:1901564 318 0.035
negative regulation of nucleic acid templated transcription GO:1903507 240 0.035
limb morphogenesis GO:0035108 1 0.035
response to abiotic stimulus GO:0009628 341 0.035
regulation of multi organism process GO:0043900 131 0.035
immune system process GO:0002376 347 0.034
detection of visible light GO:0009584 38 0.033
salivary gland development GO:0007431 162 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
regulation of tube size open tracheal system GO:0035151 43 0.033
detection of abiotic stimulus GO:0009582 66 0.032
response to external biotic stimulus GO:0043207 293 0.032
negative regulation of signal transduction GO:0009968 206 0.032
protein modification process GO:0036211 438 0.032
periodic partitioning GO:0007365 29 0.031
kidney epithelium development GO:0072073 3 0.031
catabolic process GO:0009056 409 0.031
intracellular signal transduction GO:0035556 300 0.031
imaginal disc pattern formation GO:0007447 91 0.031
transcription from rna polymerase ii promoter GO:0006366 368 0.031
sex differentiation GO:0007548 81 0.031
macromolecule catabolic process GO:0009057 161 0.030
positive regulation of developmental process GO:0051094 143 0.029
cytoskeleton dependent cytokinesis GO:0061640 81 0.029
neuron projection guidance GO:0097485 241 0.029
chemotaxis GO:0006935 249 0.029
protein localization GO:0008104 284 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.028
body morphogenesis GO:0010171 2 0.028
lateral inhibition GO:0046331 206 0.028
anatomical structure homeostasis GO:0060249 97 0.028
anterior posterior pattern specification GO:0009952 136 0.028
kidney development GO:0001822 3 0.028
protein catabolic process GO:0030163 101 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
Fly
microtubule organizing center organization GO:0031023 168 0.027
regulation of cell cycle phase transition GO:1901987 130 0.027
posttranscriptional regulation of gene expression GO:0010608 145 0.027
eye morphogenesis GO:0048592 260 0.027
establishment of tissue polarity GO:0007164 87 0.027
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.027
axon development GO:0061564 297 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
stem cell differentiation GO:0048863 117 0.026
mitotic cell cycle phase transition GO:0044772 138 0.025
cell cycle checkpoint GO:0000075 95 0.025
regulation of oocyte development GO:0060281 27 0.025
nephron epithelium development GO:0072009 3 0.025
protein transport GO:0015031 155 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
oocyte construction GO:0007308 112 0.025
morphogenesis of a polarized epithelium GO:0001738 93 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
tripartite regional subdivision GO:0007351 103 0.024
larval development GO:0002164 104 0.024
response to biotic stimulus GO:0009607 294 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
chemosensory behavior GO:0007635 106 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
endocytosis GO:0006897 310 0.023
regulation of cellular localization GO:0060341 136 0.023
phagocytosis GO:0006909 215 0.023
motor neuron axon guidance GO:0008045 58 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
negative regulation of cell cycle process GO:0010948 109 0.022
small molecule metabolic process GO:0044281 305 0.022
cell junction assembly GO:0034329 42 0.022
cellular macromolecule localization GO:0070727 220 0.022
embryonic axis specification GO:0000578 107 0.021
mesodermal cell migration GO:0008078 7 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
positive regulation of signal transduction GO:0009967 223 0.021
stem cell proliferation GO:0072089 88 0.021
negative regulation of cell cycle GO:0045786 116 0.021
sensory perception GO:0007600 196 0.021
determination of adult lifespan GO:0008340 137 0.021
regulation of cell development GO:0060284 215 0.021
regulation of epithelial cell proliferation GO:0050678 4 0.021
cellular protein modification process GO:0006464 438 0.020
eye development GO:0001654 323 0.020
oocyte axis specification GO:0007309 108 0.020
ameboidal type cell migration GO:0001667 151 0.020
detection of chemical stimulus GO:0009593 93 0.020
camera type eye development GO:0043010 4 0.020
cuticle development GO:0042335 86 0.020
ion transport GO:0006811 145 0.020
skin development GO:0043588 65 0.020
negative regulation of cell differentiation GO:0045596 143 0.019
positive regulation of signaling GO:0023056 243 0.019
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.019
mitotic spindle organization GO:0007052 220 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
protein maturation GO:0051604 71 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
regulation of embryonic development GO:0045995 68 0.019
negative regulation of developmental process GO:0051093 201 0.019
intracellular mrna localization GO:0008298 66 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
positive regulation of cell communication GO:0010647 250 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
regulation of growth GO:0040008 233 0.018
gastrulation GO:0007369 70 0.018
anterior posterior axis specification GO:0009948 109 0.018
cellular protein localization GO:0034613 160 0.018
chitin based cuticle development GO:0040003 49 0.018
regulation of molecular function GO:0065009 217 0.018
leg disc development GO:0035218 92 0.018
response to lipopolysaccharide GO:0032496 4 0.018
lipid localization GO:0010876 54 0.018
cellular response to ethanol GO:0071361 4 0.018
developmental maturation GO:0021700 172 0.017
establishment of planar polarity GO:0001736 87 0.017
compound eye morphogenesis GO:0001745 249 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
negative regulation of cell development GO:0010721 62 0.017
camera type eye morphogenesis GO:0048593 2 0.017
meiotic cell cycle process GO:1903046 132 0.017
single organism catabolic process GO:0044712 228 0.017
establishment of protein localization GO:0045184 163 0.017
nf kappab import into nucleus GO:0042348 1 0.017
sensory organ morphogenesis GO:0090596 260 0.017
imaginal disc derived wing hair organization GO:0035317 45 0.017
gland development GO:0048732 191 0.017
regulation of response to stress GO:0080134 200 0.017
hormone catabolic process GO:0042447 3 0.017
defense response GO:0006952 300 0.017
homeostatic process GO:0042592 199 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
growth GO:0040007 359 0.016
regulation of reproductive process GO:2000241 54 0.016
negative regulation of growth GO:0045926 84 0.016
gastrulation with mouth forming first GO:0001703 36 0.016
retina development in camera type eye GO:0060041 4 0.016
positive regulation of epithelial cell differentiation GO:0030858 1 0.016
cell migration GO:0016477 238 0.016
oocyte dorsal ventral axis specification GO:0007310 34 0.016
genital disc development GO:0035215 44 0.016
meiotic nuclear division GO:0007126 151 0.016
death GO:0016265 284 0.016
reproductive structure development GO:0048608 74 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
response to nitrogen compound GO:1901698 90 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
regulation of wnt signaling pathway GO:0030111 68 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
maintenance of location GO:0051235 73 0.016
cellular response to organic substance GO:0071310 132 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
regulation of protein transport GO:0051223 57 0.015
neuron recognition GO:0008038 101 0.015
chromosome organization GO:0051276 360 0.015
regulation of transport GO:0051049 181 0.015
positive regulation of defense response GO:0031349 59 0.015
cellular catabolic process GO:0044248 372 0.015
dna metabolic process GO:0006259 227 0.015
nitrogen compound transport GO:0071705 85 0.015
amine metabolic process GO:0009308 12 0.015
adult locomotory behavior GO:0008344 76 0.015
chromosome segregation GO:0007059 157 0.015
synaptic transmission GO:0007268 288 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
phosphorylation GO:0016310 294 0.015
segment polarity determination GO:0007367 25 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
heart development GO:0007507 82 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
establishment of organelle localization GO:0051656 122 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
spindle organization GO:0007051 253 0.014
cell cell junction assembly GO:0007043 38 0.014
cell growth GO:0016049 108 0.014
nuclear division GO:0000280 332 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
antimicrobial humoral response GO:0019730 99 0.014
regulation of catalytic activity GO:0050790 185 0.014
response to oxygen containing compound GO:1901700 200 0.014
single organism intracellular transport GO:1902582 207 0.014
compound eye development GO:0048749 307 0.014
synapse assembly GO:0007416 143 0.014
programmed cell death GO:0012501 257 0.014
regulation of cytoskeleton organization GO:0051493 89 0.014
taxis GO:0042330 304 0.014
cognition GO:0050890 141 0.014
Fly
intracellular transport GO:0046907 228 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
positive regulation of cell cycle GO:0045787 43 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
deactivation of rhodopsin mediated signaling GO:0016059 17 0.013
regulation of tube length open tracheal system GO:0035159 24 0.013
cellular protein catabolic process GO:0044257 83 0.013
reproductive system development GO:0061458 74 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
nephron morphogenesis GO:0072028 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
neurological system process GO:0050877 358 0.013
Fly
positive regulation of response to stimulus GO:0048584 323 0.012
positive regulation of gene expression GO:0010628 290 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
limb development GO:0060173 1 0.012
spermatogenesis GO:0007283 200 0.012
renal filtration cell differentiation GO:0061318 12 0.012
regulation of protein metabolic process GO:0051246 256 0.012
positive regulation of cell motility GO:2000147 3 0.012
developmental programmed cell death GO:0010623 138 0.012
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
epidermis development GO:0008544 65 0.012
response to hexose GO:0009746 3 0.012
aging GO:0007568 143 0.012
macromolecular complex assembly GO:0065003 256 0.012
secretion by cell GO:0032940 101 0.012
synaptic target recognition GO:0008039 45 0.012
non sensory hair organization GO:0035316 47 0.012
protein complex assembly GO:0006461 200 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
single organism cellular localization GO:1902580 180 0.012
activation of innate immune response GO:0002218 4 0.012
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.012
response to alcohol GO:0097305 95 0.012
eggshell formation GO:0030703 105 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
adult behavior GO:0030534 137 0.012
ovarian follicle cell development GO:0030707 248 0.012
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.012
cell death GO:0008219 279 0.011
regulation of protein catabolic process GO:0042176 55 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
cell junction organization GO:0034330 57 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
regulation of cell proliferation GO:0042127 163 0.011
instar larval development GO:0002168 55 0.011
response to other organism GO:0051707 293 0.011
mesenchymal cell development GO:0014031 1 0.011
embryonic organ development GO:0048568 50 0.011
malpighian tubule development GO:0072002 64 0.011
monocarboxylic acid transport GO:0015718 3 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
peripheral nervous system development GO:0007422 52 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
olfactory learning GO:0008355 56 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
embryonic hindgut morphogenesis GO:0048619 48 0.011
positive regulation of protein transport GO:0051222 37 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
response to bacterium GO:0009617 198 0.011
regulation of proteolysis GO:0030162 87 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
response to organic cyclic compound GO:0014070 89 0.010
lipid metabolic process GO:0006629 121 0.010
carbohydrate metabolic process GO:0005975 82 0.010
hindgut development GO:0061525 58 0.010
dna repair GO:0006281 54 0.010
cell cell junction organization GO:0045216 55 0.010
protein processing GO:0016485 68 0.010
leg disc morphogenesis GO:0007478 80 0.010
cellular ketone metabolic process GO:0042180 24 0.010
male gamete generation GO:0048232 201 0.010
response to endogenous stimulus GO:0009719 119 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
rna localization GO:0006403 115 0.010
pattern recognition receptor signaling pathway GO:0002221 2 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010

inx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.029
disease of anatomical entity DOID:7 0 0.029
eye and adnexa disease DOID:1492 0 0.029
nervous system disease DOID:863 0 0.029
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.013
eye disease DOID:5614 0 0.011