Drosophila melanogaster

37 known processes

Klp68D (Dmel_CG7293)

Kinesin-like protein at 68D

(Aliases: KLP68D,DmKlp68D,klp68d,KLP-5,KLP5,KLP68Ddm,CG7293,Dmel\CG7293,Klp5,KLP[[64D/68D]],KIF3B)

Klp68D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium organization GO:0044782 41 0.513
Fly
neurological system process GO:0050877 358 0.448
cilium assembly GO:0042384 38 0.336
Fly
single organism intracellular transport GO:1902582 207 0.279
intracellular transport GO:0046907 228 0.255
cell motility GO:0048870 251 0.183
protein complex disassembly GO:0043241 36 0.151
eye development GO:0001654 323 0.137
cognition GO:0050890 141 0.128
organelle assembly GO:0070925 198 0.125
Human Fly
sensory perception GO:0007600 196 0.123
establishment of localization in cell GO:0051649 402 0.118
axon cargo transport GO:0008088 29 0.113
cell cell signaling involved in cell fate commitment GO:0045168 210 0.108
sensory perception of sound GO:0007605 56 0.106
Fly
cellular catabolic process GO:0044248 372 0.100
eye morphogenesis GO:0048592 260 0.097
cellular component assembly involved in morphogenesis GO:0010927 151 0.090
Fly
sensory perception of mechanical stimulus GO:0050954 72 0.086
Fly
taxis GO:0042330 304 0.084
Fly
organic substance transport GO:0071702 257 0.083
cell death GO:0008219 279 0.083
male gamete generation GO:0048232 201 0.080
learning or memory GO:0007611 141 0.080
microtubule based transport GO:0010970 42 0.078
axon development GO:0061564 297 0.074
Fly
programmed cell death GO:0012501 257 0.073
protein modification process GO:0036211 438 0.072
catabolic process GO:0009056 409 0.071
organonitrogen compound metabolic process GO:1901564 318 0.070
spermatogenesis GO:0007283 200 0.069
cellular protein modification process GO:0006464 438 0.066
defense response to other organism GO:0098542 225 0.066
neuron projection guidance GO:0097485 241 0.066
Fly
regulation of vesicle mediated transport GO:0060627 59 0.064
regulation of nervous system development GO:0051960 248 0.064
autophagic cell death GO:0048102 83 0.063
intracellular protein transport GO:0006886 104 0.063
regulation of anatomical structure morphogenesis GO:0022603 242 0.062
cellular protein localization GO:0034613 160 0.060
cellular protein complex disassembly GO:0043624 35 0.059
tissue death GO:0016271 102 0.059
cilium morphogenesis GO:0060271 39 0.058
Fly
localization of cell GO:0051674 257 0.058
vesicle mediated transport GO:0016192 381 0.057
positive regulation of multicellular organismal process GO:0051240 143 0.057
dendrite development GO:0016358 204 0.055
negative regulation of cellular metabolic process GO:0031324 382 0.054
response to external biotic stimulus GO:0043207 293 0.054
regulation of localization GO:0032879 275 0.053
positive regulation of response to stimulus GO:0048584 323 0.053
Fly
small molecule metabolic process GO:0044281 305 0.052
photoreceptor cell differentiation GO:0046530 170 0.051
embryonic morphogenesis GO:0048598 206 0.051
nonmotile primary cilium assembly GO:0035058 8 0.050
Fly
immune system process GO:0002376 347 0.048
lipid metabolic process GO:0006629 121 0.048
negative regulation of neuron death GO:1901215 18 0.048
sensory organ morphogenesis GO:0090596 260 0.048
regulation of cellular ketone metabolic process GO:0010565 3 0.048
regulation of molecular function GO:0065009 217 0.047
organic substance catabolic process GO:1901575 308 0.047
protein localization GO:0008104 284 0.047
positive regulation of molecular function GO:0044093 136 0.047
multicellular organismal aging GO:0010259 140 0.046
tube development GO:0035295 244 0.046
positive regulation of phosphate metabolic process GO:0045937 139 0.046
tube morphogenesis GO:0035239 191 0.045
positive regulation of transport GO:0051050 92 0.045
autophagy GO:0006914 108 0.044
nitrogen compound transport GO:0071705 85 0.044
positive regulation of phosphorus metabolic process GO:0010562 139 0.043
salivary gland development GO:0007431 162 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
salivary gland histolysis GO:0035070 88 0.042
developmental programmed cell death GO:0010623 138 0.042
amine metabolic process GO:0009308 12 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
apoptotic process GO:0006915 159 0.041
protein import into nucleus GO:0006606 51 0.041
axonogenesis GO:0007409 290 0.041
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.041
cellular lipid metabolic process GO:0044255 83 0.040
establishment of protein localization GO:0045184 163 0.040
dephosphorylation GO:0016311 51 0.040
regulation of hydrolase activity GO:0051336 97 0.040
protein transport GO:0015031 155 0.039
cytoskeleton dependent cytokinesis GO:0061640 81 0.039
lateral inhibition GO:0046331 206 0.039
organophosphate metabolic process GO:0019637 195 0.039
single organism cell adhesion GO:0098602 47 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
enzyme linked receptor protein signaling pathway GO:0007167 179 0.038
regulation of cell death GO:0010941 173 0.037
positive regulation of cell communication GO:0010647 250 0.037
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
g protein coupled receptor signaling pathway GO:0007186 136 0.037
appendage morphogenesis GO:0035107 397 0.037
death GO:0016265 284 0.036
regulation of receptor mediated endocytosis GO:0048259 9 0.036
organonitrogen compound biosynthetic process GO:1901566 117 0.035
proteolysis GO:0006508 192 0.035
gland morphogenesis GO:0022612 145 0.035
regulation of endocytosis GO:0030100 37 0.035
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
eye photoreceptor cell differentiation GO:0001754 145 0.034
single organism cellular localization GO:1902580 180 0.034
establishment or maintenance of cell polarity GO:0007163 167 0.034
salivary gland cell autophagic cell death GO:0035071 83 0.034
defense response GO:0006952 300 0.034
response to biotic stimulus GO:0009607 294 0.033
macromolecular complex disassembly GO:0032984 37 0.033
exocrine system development GO:0035272 162 0.033
single organism catabolic process GO:0044712 228 0.033
membrane budding GO:0006900 4 0.033
protein modification by small protein conjugation or removal GO:0070647 106 0.032
cell projection assembly GO:0030031 94 0.032
Fly
inositol lipid mediated signaling GO:0048017 4 0.032
muscle structure development GO:0061061 224 0.032
dendrite morphogenesis GO:0048813 199 0.032
endomembrane system organization GO:0010256 119 0.032
positive regulation of nucleotide metabolic process GO:0045981 55 0.031
cellular response to nutrient levels GO:0031669 62 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
cellular amine metabolic process GO:0044106 12 0.031
gastrulation GO:0007369 70 0.031
response to other organism GO:0051707 293 0.030
purine nucleotide metabolic process GO:0006163 146 0.030
compound eye photoreceptor cell differentiation GO:0001751 140 0.030
histolysis GO:0007559 102 0.029
regulation of cell differentiation GO:0045595 302 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.028
actin filament based process GO:0030029 220 0.028
digestive tract morphogenesis GO:0048546 127 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
rhythmic process GO:0048511 106 0.027
determination of adult lifespan GO:0008340 137 0.027
positive regulation of rna biosynthetic process GO:1902680 266 0.027
positive regulation of immune response GO:0050778 63 0.027
nucleotide metabolic process GO:0009117 161 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
protein localization to organelle GO:0033365 82 0.026
organic acid metabolic process GO:0006082 103 0.026
secretion GO:0046903 109 0.026
positive regulation of signaling GO:0023056 243 0.026
Fly
cellular macromolecular complex assembly GO:0034622 153 0.026
regulation of cell development GO:0060284 215 0.026
intracellular signal transduction GO:0035556 300 0.026
positive regulation of cell motility GO:2000147 3 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
positive regulation of cell differentiation GO:0045597 64 0.025
developmental growth GO:0048589 280 0.025
regulation of catalytic activity GO:0050790 185 0.025
regulation of cell cycle process GO:0010564 181 0.024
Rat
immune effector process GO:0002252 98 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
cellular metal ion homeostasis GO:0006875 31 0.024
single organism biosynthetic process GO:0044711 206 0.024
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.024
response to oxidative stress GO:0006979 86 0.024
single organism behavior GO:0044708 391 0.024
vesicle organization GO:0016050 44 0.024
negative regulation of biosynthetic process GO:0009890 277 0.023
regulation of autophagy GO:0010506 62 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
regulation of rab protein signal transduction GO:0032483 7 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
maintenance of location GO:0051235 73 0.023
cellular ketone metabolic process GO:0042180 24 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.023
homeostatic process GO:0042592 199 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
centrosome organization GO:0051297 163 0.022
compound eye morphogenesis GO:0001745 249 0.022
transmembrane transport GO:0055085 139 0.022
positive regulation of nucleoside metabolic process GO:0045979 47 0.022
phosphatidylinositol mediated signaling GO:0048015 4 0.022
camera type eye development GO:0043010 4 0.022
regulation of neuron death GO:1901214 26 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
inorganic cation transmembrane transport GO:0098662 61 0.022
microtubule organizing center organization GO:0031023 168 0.022
glycerolipid metabolic process GO:0046486 34 0.021
protein processing GO:0016485 68 0.021
regulation of transport GO:0051049 181 0.021
periodic partitioning GO:0007365 29 0.021
cellular macromolecule localization GO:0070727 220 0.021
neuron death GO:0070997 27 0.021
positive regulation of ras gtpase activity GO:0032320 36 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.021
regulation of neuron differentiation GO:0045664 103 0.021
regulation of protein localization GO:0032880 76 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
macromolecular complex assembly GO:0065003 256 0.021
Human
glycosyl compound metabolic process GO:1901657 127 0.021
ion transport GO:0006811 145 0.021
phagocytosis GO:0006909 215 0.021
regulation of synapse organization GO:0050807 110 0.021
glycerophospholipid metabolic process GO:0006650 23 0.021
cytoskeleton dependent intracellular transport GO:0030705 44 0.021
protein maturation GO:0051604 71 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
organelle localization GO:0051640 148 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.020
regulation of intracellular transport GO:0032386 64 0.020
macromolecule catabolic process GO:0009057 161 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
phosphorylation GO:0016310 294 0.020
positive regulation of cell migration GO:0030335 2 0.020
neuron recognition GO:0008038 101 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of neurogenesis GO:0050767 158 0.020
regulation of cell cell adhesion GO:0022407 21 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
carbohydrate metabolic process GO:0005975 82 0.019
biological adhesion GO:0022610 138 0.019
regulation of cellular component size GO:0032535 98 0.019
single organismal cell cell adhesion GO:0016337 45 0.019
organophosphate catabolic process GO:0046434 112 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
negative regulation of gene expression GO:0010629 387 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
gland development GO:0048732 191 0.019
rhythmic behavior GO:0007622 76 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
cell adhesion GO:0007155 136 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
positive regulation of receptor mediated endocytosis GO:0048260 7 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
cytokinesis GO:0000910 90 0.018
Rat
memory GO:0007613 94 0.018
regulation of protein depolymerization GO:1901879 27 0.018
positive regulation of intracellular transport GO:0032388 42 0.018
protein import GO:0017038 55 0.018
head development GO:0060322 135 0.018
negative regulation of neuron apoptotic process GO:0043524 14 0.018
purine containing compound metabolic process GO:0072521 155 0.018
positive regulation of catabolic process GO:0009896 105 0.018
regulation of programmed cell death GO:0043067 152 0.018
protein phosphorylation GO:0006468 169 0.018
regulation of purine nucleotide metabolic process GO:1900542 62 0.018
positive regulation of cellular component organization GO:0051130 156 0.018
salivary gland morphogenesis GO:0007435 145 0.018
chromatin assembly or disassembly GO:0006333 52 0.017
regulation of protein transport GO:0051223 57 0.017
regulation of immune response GO:0050776 118 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
brain development GO:0007420 120 0.017
actin cytoskeleton organization GO:0030036 206 0.017
nuclear import GO:0051170 51 0.017
chemotaxis GO:0006935 249 0.017
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.017
protein localization to nucleus GO:0034504 55 0.017
positive regulation of rab gtpase activity GO:0032851 7 0.017
endosome organization GO:0007032 9 0.017
organic cyclic compound catabolic process GO:1901361 168 0.016
wing disc morphogenesis GO:0007472 344 0.016
cytoplasmic transport GO:0016482 130 0.016
circadian behavior GO:0048512 76 0.016
ras protein signal transduction GO:0007265 88 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
aromatic compound catabolic process GO:0019439 166 0.016
protein modification by small protein conjugation GO:0032446 79 0.015
aging GO:0007568 143 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
myotube cell development GO:0014904 3 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
single organism nuclear import GO:1902593 51 0.015
open tracheal system development GO:0007424 204 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
response to axon injury GO:0048678 12 0.015
positive regulation of immune system process GO:0002684 68 0.015
digestive tract development GO:0048565 149 0.015
microtubule based movement GO:0007018 51 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
cellular response to starvation GO:0009267 61 0.015
regulation of organelle organization GO:0033043 196 0.015
regulation of gtp catabolic process GO:0033124 44 0.015
regulation of protein import into nucleus GO:0042306 28 0.015
locomotory behavior GO:0007626 176 0.015
cell proliferation GO:0008283 299 0.015
positive regulation of developmental process GO:0051094 143 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.015
single organism membrane fusion GO:0044801 42 0.015
regulation of cellular localization GO:0060341 136 0.015
muscle cell differentiation GO:0042692 103 0.014
cellular component maintenance GO:0043954 23 0.014
negative regulation of cell death GO:0060548 81 0.014
membrane organization GO:0061024 112 0.014
positive regulation of nervous system development GO:0051962 69 0.014
regulation of response to external stimulus GO:0032101 115 0.014
purine containing compound catabolic process GO:0072523 112 0.014
tracheal outgrowth open tracheal system GO:0007426 18 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
protein targeting GO:0006605 64 0.014
mitochondrion distribution GO:0048311 10 0.014
response to bacterium GO:0009617 198 0.014
hemocyte differentiation GO:0042386 38 0.014
regulation of cell shape GO:0008360 113 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
regulation of endopeptidase activity GO:0052548 36 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of protein metabolic process GO:0051246 256 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
protein targeting to nucleus GO:0044744 51 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
protein ubiquitination GO:0016567 70 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
cellular protein complex assembly GO:0043623 71 0.013
regulation of catabolic process GO:0009894 170 0.013
regulation of canonical wnt signaling pathway GO:0060828 15 0.013
heterocycle catabolic process GO:0046700 166 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
positive regulation of rho gtpase activity GO:0032321 19 0.013
central nervous system development GO:0007417 201 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
compound eye development GO:0048749 307 0.013
ameboidal type cell migration GO:0001667 151 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
neuron apoptotic process GO:0051402 17 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
rac protein signal transduction GO:0016601 3 0.013
immune response GO:0006955 246 0.013
positive regulation of cell development GO:0010720 61 0.013
activation of cysteine type endopeptidase activity GO:0097202 17 0.013
kidney development GO:0001822 3 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
positive regulation of endocytosis GO:0045807 22 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
regulation of phosphorylation GO:0042325 147 0.013
endocytosis GO:0006897 310 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
sperm motility GO:0030317 12 0.013
guanosine containing compound metabolic process GO:1901068 74 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of cell projection organization GO:0031344 92 0.012
positive regulation of autophagy GO:0010508 21 0.012
chitin based cuticle development GO:0040003 49 0.012
myotube differentiation GO:0014902 46 0.012
regulation of cellular component movement GO:0051270 42 0.012
regulation of lipid transport GO:0032368 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
border follicle cell migration GO:0007298 113 0.012
actomyosin structure organization GO:0031032 56 0.012
respiratory system development GO:0060541 213 0.012
hindbrain development GO:0030902 2 0.012
lipid localization GO:0010876 54 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
response to radiation GO:0009314 155 0.012
regulation of protein processing GO:0070613 32 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.012
regulation of cell adhesion GO:0030155 27 0.011
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.011
positive regulation of signal transduction GO:0009967 223 0.011
Fly
ribonucleoside catabolic process GO:0042454 112 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
positive regulation of protein modification process GO:0031401 58 0.011
vesicle fusion GO:0006906 19 0.011
positive regulation of gene expression GO:0010628 290 0.011
organelle fusion GO:0048284 46 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
regulation of rab gtpase activity GO:0032313 7 0.011
golgi organization GO:0007030 66 0.011
cation transport GO:0006812 110 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
skeletal muscle organ development GO:0060538 48 0.011
nucleotide catabolic process GO:0009166 109 0.011
gtp metabolic process GO:0046039 72 0.011
defense response to bacterium GO:0042742 178 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
response to abiotic stimulus GO:0009628 341 0.011
adult locomotory behavior GO:0008344 76 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
response to endogenous stimulus GO:0009719 119 0.011
peptidyl tyrosine modification GO:0018212 24 0.011
positive regulation of protein deacetylation GO:0090312 2 0.011
epithelial cell differentiation GO:0030855 322 0.010
developmental maturation GO:0021700 172 0.010
single organism membrane organization GO:0044802 93 0.010
protein modification by small protein removal GO:0070646 28 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
developmental cell growth GO:0048588 52 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
regulation of actin cytoskeleton organization GO:0032956 42 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
cellular homeostasis GO:0019725 80 0.010

Klp68D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.036
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.021
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.014
cancer DOID:162 0 0.013