Drosophila melanogaster

0 known processes

CG4653 (Dmel_CG4653)

CG4653 gene product from transcript CG4653-RA

(Aliases: SPH179,Dmel\CG4653)

CG4653 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 103 0.155
carboxylic acid metabolic process GO:0019752 92 0.140
oxoacid metabolic process GO:0043436 103 0.126
xenobiotic catabolic process GO:0042178 1 0.105
endocytosis GO:0006897 310 0.096
steroid catabolic process GO:0006706 1 0.094
response to abiotic stimulus GO:0009628 341 0.087
catabolic process GO:0009056 409 0.083
single organism catabolic process GO:0044712 228 0.081
androgen metabolic process GO:0008209 1 0.081
small molecule metabolic process GO:0044281 305 0.078
vesicle mediated transport GO:0016192 381 0.077
organic substance catabolic process GO:1901575 308 0.073
lipid metabolic process GO:0006629 121 0.069
lipid catabolic process GO:0016042 21 0.066
neurological system process GO:0050877 358 0.065
cellular catabolic process GO:0044248 372 0.059
monocarboxylic acid metabolic process GO:0032787 29 0.055
response to organic substance GO:0010033 284 0.054
aggressive behavior GO:0002118 63 0.053
cellular response to ethanol GO:0071361 4 0.053
phagocytosis GO:0006909 215 0.052
response to lipopolysaccharide GO:0032496 4 0.052
organonitrogen compound metabolic process GO:1901564 318 0.051
lateral inhibition GO:0046331 206 0.050
response to external biotic stimulus GO:0043207 293 0.050
Fly
hormone catabolic process GO:0042447 3 0.050
estrogen metabolic process GO:0008210 1 0.049
response to extracellular stimulus GO:0009991 116 0.048
imaginal disc derived appendage development GO:0048737 399 0.047
sensory perception GO:0007600 196 0.045
cellular protein modification process GO:0006464 438 0.042
appendage morphogenesis GO:0035107 397 0.042
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
defense response to other organism GO:0098542 225 0.040
Fly
protein modification process GO:0036211 438 0.040
post embryonic appendage morphogenesis GO:0035120 385 0.040
response to starvation GO:0042594 97 0.039
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
ethanolamine containing compound metabolic process GO:0042439 4 0.039
regulation of response to stress GO:0080134 200 0.037
appendage development GO:0048736 401 0.035
cellular lipid metabolic process GO:0044255 83 0.035
wing disc morphogenesis GO:0007472 344 0.035
oxidation reduction process GO:0055114 123 0.034
sensory perception of chemical stimulus GO:0007606 116 0.034
single organism behavior GO:0044708 391 0.034
lauric acid metabolic process GO:0048252 1 0.034
regionalization GO:0003002 416 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
response to nutrient levels GO:0031667 114 0.033
organic substance transport GO:0071702 257 0.033
sensory perception of smell GO:0007608 80 0.032
cholesterol homeostasis GO:0042632 3 0.032
response to organophosphorus GO:0046683 2 0.032
cellular response to dna damage stimulus GO:0006974 223 0.031
organelle fission GO:0048285 340 0.031
sterol homeostasis GO:0055092 4 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.028
nuclear division GO:0000280 332 0.027
amine metabolic process GO:0009308 12 0.027
phosphorylation GO:0016310 294 0.027
aging GO:0007568 143 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
inter male aggressive behavior GO:0002121 60 0.026
response to other organism GO:0051707 293 0.026
Fly
vitamin metabolic process GO:0006766 2 0.025
response to oxygen containing compound GO:1901700 200 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
cellular ketone metabolic process GO:0042180 24 0.025
regulation of hormone levels GO:0010817 40 0.025
regulation of anatomical structure size GO:0090066 163 0.025
body morphogenesis GO:0010171 2 0.024
positive regulation of cell communication GO:0010647 250 0.024
Fly
epithelial cell differentiation GO:0030855 322 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
aromatic compound catabolic process GO:0019439 166 0.024
cellular amine metabolic process GO:0044106 12 0.024
intracellular signal transduction GO:0035556 300 0.024
positive regulation of signaling GO:0023056 243 0.024
Fly
positive regulation of signal transduction GO:0009967 223 0.024
Fly
multi organism behavior GO:0051705 175 0.024
regulation of localization GO:0032879 275 0.023
benzene containing compound metabolic process GO:0042537 3 0.023
cellular response to endogenous stimulus GO:0071495 80 0.023
neuron projection guidance GO:0097485 241 0.023
defense response GO:0006952 300 0.023
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
positive regulation of response to stimulus GO:0048584 323 0.022
Fly
cellular lipid catabolic process GO:0044242 16 0.022
neutral lipid catabolic process GO:0046461 3 0.022
cell motility GO:0048870 251 0.022
acylglycerol biosynthetic process GO:0046463 2 0.022
heterocycle catabolic process GO:0046700 166 0.022
eye development GO:0001654 323 0.022
fatty acid metabolic process GO:0006631 20 0.022
chemotaxis GO:0006935 249 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
response to organic cyclic compound GO:0014070 89 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
forebrain development GO:0030900 2 0.021
single organism biosynthetic process GO:0044711 206 0.021
cell migration GO:0016477 238 0.021
response to biotic stimulus GO:0009607 294 0.021
Fly
negative regulation of cell communication GO:0010648 223 0.021
carbohydrate metabolic process GO:0005975 82 0.021
anion homeostasis GO:0055081 3 0.020
developmental growth GO:0048589 280 0.020
gland development GO:0048732 191 0.020
camera type eye development GO:0043010 4 0.020
monocarboxylic acid catabolic process GO:0072329 10 0.020
cell death GO:0008219 279 0.020
regulation of cell cycle GO:0051726 291 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
connective tissue development GO:0061448 3 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
localization of cell GO:0051674 257 0.020
regulation of cell differentiation GO:0045595 302 0.020
growth GO:0040007 359 0.020
ovarian follicle cell development GO:0030707 248 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
transmembrane transport GO:0055085 139 0.019
epithelial cell development GO:0002064 274 0.019
axon guidance GO:0007411 233 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
cell proliferation GO:0008283 299 0.019
compound eye development GO:0048749 307 0.019
death GO:0016265 284 0.019
response to bacterium GO:0009617 198 0.019
Fly
neutral lipid biosynthetic process GO:0046460 2 0.019
chromosome organization GO:0051276 360 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
cellular macromolecule localization GO:0070727 220 0.018
glycerolipid catabolic process GO:0046503 3 0.018
vitamin biosynthetic process GO:0009110 1 0.018
synaptic transmission GO:0007268 288 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
response to radiation GO:0009314 155 0.018
sensory organ morphogenesis GO:0090596 260 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
negative regulation of signaling GO:0023057 219 0.018
response to ethanol GO:0045471 59 0.018
immune response activating signal transduction GO:0002757 2 0.018
negative regulation of gene expression GO:0010629 387 0.018
response to endogenous stimulus GO:0009719 119 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
regulation of cell death GO:0010941 173 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
response to monosaccharide GO:0034284 4 0.018
regulation of sequestering of triglyceride GO:0010889 3 0.017
fat soluble vitamin metabolic process GO:0006775 1 0.017
taxis GO:0042330 304 0.017
secondary metabolite catabolic process GO:0090487 1 0.017
acetate ester metabolic process GO:1900619 2 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
cellular hormone metabolic process GO:0034754 23 0.017
phosphatidylethanolamine metabolic process GO:0046337 1 0.017
macromolecular complex assembly GO:0065003 256 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
secondary metabolic process GO:0019748 75 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
response to copper ion GO:0046688 4 0.017
triglyceride biosynthetic process GO:0019432 2 0.017
organophosphate metabolic process GO:0019637 195 0.017
positive regulation of cell motility GO:2000147 3 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
acetylcholine catabolic process GO:0006581 1 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
cellular response to hormone stimulus GO:0032870 44 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
fatty acid beta oxidation GO:0006635 6 0.016
eye morphogenesis GO:0048592 260 0.016
positive regulation of gene expression GO:0010628 290 0.016
regulation of transport GO:0051049 181 0.016
neurotransmitter metabolic process GO:0042133 2 0.016
response to nitrogen compound GO:1901698 90 0.016
response to light stimulus GO:0009416 124 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
single organism cellular localization GO:1902580 180 0.016
compound eye morphogenesis GO:0001745 249 0.016
chromosome segregation GO:0007059 157 0.016
l amino acid import GO:0043092 2 0.016
chaeta development GO:0022416 97 0.016
determination of adult lifespan GO:0008340 137 0.016
regulation of developmental growth GO:0048638 174 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
negative regulation of signal transduction GO:0009968 206 0.016
polyol biosynthetic process GO:0046173 3 0.016
epithelial cell migration GO:0010631 148 0.016
male gamete generation GO:0048232 201 0.016
choline catabolic process GO:0042426 1 0.016
cuticle development GO:0042335 86 0.016
establishment of protein localization GO:0045184 163 0.016
kidney development GO:0001822 3 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
acylglycerol catabolic process GO:0046464 3 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
immune system process GO:0002376 347 0.015
Fly
regulation of programmed cell death GO:0043067 152 0.015
cell adhesion GO:0007155 136 0.015
chemical homeostasis GO:0048878 92 0.015
peptidyl amino acid modification GO:0018193 105 0.015
regulation of cellular response to stress GO:0080135 89 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
protein transport GO:0015031 155 0.015
cellular response to organic substance GO:0071310 132 0.015
protein complex assembly GO:0006461 200 0.015
maintenance of location GO:0051235 73 0.015
protein complex biogenesis GO:0070271 201 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
cell recognition GO:0008037 102 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
regulation of catalytic activity GO:0050790 185 0.015
meiotic cell cycle GO:0051321 171 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
protein phosphorylation GO:0006468 169 0.015
proteolysis GO:0006508 192 0.015
immune response GO:0006955 246 0.015
Fly
homeostatic process GO:0042592 199 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
chromatin modification GO:0016568 147 0.015
regulation of molecular function GO:0065009 217 0.014
open tracheal system development GO:0007424 204 0.014
protein localization GO:0008104 284 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
intracellular transport GO:0046907 228 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
programmed cell death GO:0012501 257 0.014
regulation of protein metabolic process GO:0051246 256 0.014
fat soluble vitamin biosynthetic process GO:0042362 1 0.014
response to alcohol GO:0097305 95 0.014
small molecule catabolic process GO:0044282 21 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
telencephalon development GO:0021537 2 0.014
toxin catabolic process GO:0009407 1 0.014
regulation of growth GO:0040008 233 0.014
response to organonitrogen compound GO:0010243 75 0.014
ameboidal type cell migration GO:0001667 151 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
response to glucose GO:0009749 2 0.014
multicellular organismal aging GO:0010259 140 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
biological adhesion GO:0022610 138 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
imaginal disc pattern formation GO:0007447 91 0.014
tissue migration GO:0090130 155 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
acetylcholine metabolic process GO:0008291 2 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
organophosphate catabolic process GO:0046434 112 0.014
respiratory system development GO:0060541 213 0.014
negative regulation of developmental process GO:0051093 201 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
organic acid catabolic process GO:0016054 16 0.014
toxin metabolic process GO:0009404 2 0.014
cell division GO:0051301 248 0.013
cholesterol transport GO:0030301 2 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
tube development GO:0035295 244 0.013
response to hexose GO:0009746 3 0.013
cellular response to organonitrogen compound GO:0071417 36 0.013
phospholipid homeostasis GO:0055091 1 0.013
lipid localization GO:0010876 54 0.013
neuron recognition GO:0008038 101 0.013
innate immune response GO:0045087 144 0.013
Fly
signal transduction by phosphorylation GO:0023014 107 0.013
regulation of cell development GO:0060284 215 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
cellular biogenic amine catabolic process GO:0042402 1 0.013
positive regulation of lipid storage GO:0010884 4 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
rna localization GO:0006403 115 0.013
segmentation GO:0035282 207 0.013
hormone metabolic process GO:0042445 33 0.013
macromolecule catabolic process GO:0009057 161 0.013
positive regulation of cell migration GO:0030335 2 0.013
cellular homeostasis GO:0019725 80 0.013
multi multicellular organism process GO:0044706 123 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of catabolic process GO:0009894 170 0.013
regulation of cell cycle process GO:0010564 181 0.013
dna metabolic process GO:0006259 227 0.012
chromatin remodeling GO:0006338 72 0.012
ovarian follicle cell migration GO:0007297 121 0.012
apoptotic process GO:0006915 159 0.012
response to ketone GO:1901654 34 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
fatty acid oxidation GO:0019395 6 0.012
sensory perception of pain GO:0019233 4 0.012
insecticide catabolic process GO:0046701 1 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
axon development GO:0061564 297 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
developmental maturation GO:0021700 172 0.012
spermatogenesis GO:0007283 200 0.012
chromatin organization GO:0006325 207 0.012
regulation of phosphorylation GO:0042325 147 0.012
locomotory behavior GO:0007626 176 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
mitotic nuclear division GO:0007067 213 0.012
hindbrain development GO:0030902 2 0.012
cellular protein localization GO:0034613 160 0.012
cellular response to peptide hormone stimulus GO:0071375 28 0.012
positive regulation of transport GO:0051050 92 0.012
triglyceride catabolic process GO:0019433 3 0.012
purine containing compound metabolic process GO:0072521 155 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
medium chain fatty acid metabolic process GO:0051791 1 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
developmental pigmentation GO:0048066 68 0.012
positive regulation of catabolic process GO:0009896 105 0.012
cell cycle phase transition GO:0044770 140 0.012
meiotic cell cycle process GO:1903046 132 0.012
ion transport GO:0006811 145 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
camera type eye morphogenesis GO:0048593 2 0.012
somatic muscle development GO:0007525 66 0.011
nitrogen compound transport GO:0071705 85 0.011
intracellular protein transport GO:0006886 104 0.011
regulation of cellular localization GO:0060341 136 0.011
ion homeostasis GO:0050801 55 0.011
tube morphogenesis GO:0035239 191 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
synaptic target recognition GO:0008039 45 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
l glutamate import GO:0051938 1 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
activation of innate immune response GO:0002218 4 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
regulation of lipid transport GO:0032368 3 0.011
rna processing GO:0006396 147 0.011
regulation of multi organism process GO:0043900 131 0.011
epithelium migration GO:0090132 148 0.011
positive regulation of molecular function GO:0044093 136 0.011
insecticide metabolic process GO:0017143 2 0.011
limb development GO:0060173 1 0.011
positive regulation of sequestering of triglyceride GO:0010890 1 0.011
establishment of localization in cell GO:0051649 402 0.011
response to decreased oxygen levels GO:0036293 58 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of mapk cascade GO:0043408 92 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
reproductive behavior GO:0019098 122 0.011
notch signaling pathway GO:0007219 120 0.011
adult behavior GO:0030534 137 0.011
lipid biosynthetic process GO:0008610 46 0.011
ion transmembrane transport GO:0034220 122 0.011
axis specification GO:0009798 167 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
tissue morphogenesis GO:0048729 297 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
endomembrane system organization GO:0010256 119 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
response to mercury ion GO:0046689 3 0.011
regulation of organelle organization GO:0033043 196 0.011
cytoplasmic transport GO:0016482 130 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
wound healing GO:0042060 75 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
ras protein signal transduction GO:0007265 88 0.011
defense response to bacterium GO:0042742 178 0.011
Fly
monocarboxylic acid transport GO:0015718 3 0.011
phosphate ion transport GO:0006817 4 0.011
embryonic pattern specification GO:0009880 174 0.011
histone modification GO:0016570 106 0.011
choline metabolic process GO:0019695 1 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of apoptotic process GO:0042981 130 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
meiotic chromosome segregation GO:0045132 59 0.010
establishment of rna localization GO:0051236 47 0.010
response to peptide GO:1901652 29 0.010
peripheral nervous system development GO:0007422 52 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
cation transport GO:0006812 110 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
alcohol metabolic process GO:0006066 25 0.010
synapse organization GO:0050808 196 0.010
cellular chemical homeostasis GO:0055082 40 0.010
negative regulation of cell death GO:0060548 81 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
steroid metabolic process GO:0008202 20 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
wing disc pattern formation GO:0035222 66 0.010
anterior posterior pattern specification GO:0009952 136 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
organelle localization GO:0051640 148 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
cellular response to ketone GO:1901655 17 0.010
positive regulation of immune response GO:0050778 63 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
dna integrity checkpoint GO:0031570 81 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
carboxylic acid catabolic process GO:0046395 16 0.010

CG4653 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
diabetes mellitus DOID:9351 0 0.023
type 2 diabetes mellitus DOID:9352 0 0.023
disease of metabolism DOID:0014667 0 0.023
carbohydrate metabolism disease DOID:0050013 0 0.023
glucose metabolism disease DOID:4194 0 0.023
acquired metabolic disease DOID:0060158 0 0.023
nervous system disease DOID:863 0 0.022
cardiovascular system disease DOID:1287 0 0.020
inherited metabolic disorder DOID:655 0 0.019
familial hyperlipidemia DOID:1168 0 0.016
lipid metabolism disorder DOID:3146 0 0.016
sensory system disease DOID:0050155 0 0.016
vascular disease DOID:178 0 0.016
hypertension DOID:10763 0 0.015
artery disease DOID:0050828 0 0.015
essential hypertension DOID:10825 0 0.015
hair disease DOID:421 0 0.014
integumentary system disease DOID:16 0 0.014
hypotrichosis DOID:4535 0 0.014
renal tubular transport disease DOID:447 0 0.014
kidney disease DOID:557 0 0.014
urinary system disease DOID:18 0 0.014
musculoskeletal system disease DOID:17 0 0.012
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010