Drosophila melanogaster

44 known processes

CG4221 (Dmel_CG4221)

CG4221 gene product from transcript CG4221-RA

(Aliases: Dmel\CG4221)

CG4221 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
growth GO:0040007 359 0.101
negative regulation of cell communication GO:0010648 223 0.081
negative regulation of growth GO:0045926 84 0.074
regulation of multicellular organismal development GO:2000026 414 0.073
negative regulation of signaling GO:0023057 219 0.071
mitotic dna damage checkpoint GO:0044773 74 0.067
g2 dna damage checkpoint GO:0031572 69 0.062
mitotic dna integrity checkpoint GO:0044774 75 0.062
negative regulation of response to stimulus GO:0048585 258 0.061
negative regulation of developmental growth GO:0048640 64 0.060
developmental growth GO:0048589 280 0.060
programmed cell death GO:0012501 257 0.058
synapse assembly GO:0007416 143 0.057
organelle fission GO:0048285 340 0.052
phosphorylation GO:0016310 294 0.052
negative regulation of developmental process GO:0051093 201 0.049
response to oxygen containing compound GO:1901700 200 0.048
mitotic cell cycle phase transition GO:0044772 138 0.046
regulation of nervous system development GO:0051960 248 0.046
death GO:0016265 284 0.045
chromosome condensation GO:0030261 41 0.045
negative regulation of signal transduction GO:0009968 206 0.042
enzyme linked receptor protein signaling pathway GO:0007167 179 0.042
regulation of synapse assembly GO:0051963 94 0.041
protein localization GO:0008104 284 0.040
response to endogenous stimulus GO:0009719 119 0.040
chromosome organization GO:0051276 360 0.039
dna damage checkpoint GO:0000077 78 0.038
negative regulation of multicellular organismal process GO:0051241 142 0.038
intracellular signal transduction GO:0035556 300 0.037
regulation of intracellular signal transduction GO:1902531 236 0.037
negative regulation of cellular metabolic process GO:0031324 382 0.036
regulation of cell cycle GO:0051726 291 0.036
dna integrity checkpoint GO:0031570 81 0.036
regulation of programmed cell death GO:0043067 152 0.035
response to organic substance GO:0010033 284 0.035
positive regulation of response to stimulus GO:0048584 323 0.035
regulation of insulin receptor signaling pathway GO:0046626 17 0.035
regulation of phosphate metabolic process GO:0019220 210 0.035
single organism biosynthetic process GO:0044711 206 0.034
regulation of growth GO:0040008 233 0.034
posttranscriptional regulation of gene expression GO:0010608 145 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
compound eye development GO:0048749 307 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
response to nitrogen compound GO:1901698 90 0.033
cell cycle phase transition GO:0044770 140 0.033
developmental maturation GO:0021700 172 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
regulation of developmental growth GO:0048638 174 0.033
negative regulation of cell cycle phase transition GO:1901988 103 0.032
neuromuscular junction development GO:0007528 149 0.032
centrosome organization GO:0051297 163 0.032
mitotic nuclear division GO:0007067 213 0.032
appendage development GO:0048736 401 0.032
response to organonitrogen compound GO:0010243 75 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
regulation of response to stress GO:0080134 200 0.031
nuclear division GO:0000280 332 0.031
compound eye morphogenesis GO:0001745 249 0.031
positive regulation of signal transduction GO:0009967 223 0.030
dna conformation change GO:0071103 105 0.030
wing disc morphogenesis GO:0007472 344 0.030
forebrain development GO:0030900 2 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
appendage morphogenesis GO:0035107 397 0.029
positive regulation of signaling GO:0023056 243 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
cell death GO:0008219 279 0.028
synaptic growth at neuromuscular junction GO:0051124 119 0.028
innate immune response GO:0045087 144 0.028
protein modification process GO:0036211 438 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
dna metabolic process GO:0006259 227 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
microtubule organizing center organization GO:0031023 168 0.026
regulation of cell cycle phase transition GO:1901987 130 0.026
dna packaging GO:0006323 91 0.026
centrosome duplication GO:0051298 121 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
body morphogenesis GO:0010171 2 0.025
mitotic g2 m transition checkpoint GO:0044818 70 0.025
immune response GO:0006955 246 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
neurological system process GO:0050877 358 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
insulin receptor signaling pathway GO:0008286 25 0.024
organonitrogen compound biosynthetic process GO:1901566 117 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
negative regulation of nervous system development GO:0051961 92 0.023
negative regulation of cell cycle GO:0045786 116 0.023
regulation of apoptotic process GO:0042981 130 0.023
locomotory behavior GO:0007626 176 0.023
mitotic cell cycle checkpoint GO:0007093 88 0.022
actin cytoskeleton organization GO:0030036 206 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
defense response to bacterium GO:0042742 178 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
epithelial cell differentiation GO:0030855 322 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
synapse organization GO:0050808 196 0.022
positive regulation of cell communication GO:0010647 250 0.021
cellular protein modification process GO:0006464 438 0.021
camera type eye development GO:0043010 4 0.021
stress activated protein kinase signaling cascade GO:0031098 55 0.021
defense response GO:0006952 300 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
organophosphate metabolic process GO:0019637 195 0.021
regulation of cell cycle process GO:0010564 181 0.020
cellular macromolecule localization GO:0070727 220 0.020
apoptotic process GO:0006915 159 0.020
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.020
cellular response to organic substance GO:0071310 132 0.020
humoral immune response GO:0006959 117 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
regulation of protein stability GO:0031647 43 0.020
response to abiotic stimulus GO:0009628 341 0.019
immune system process GO:0002376 347 0.019
cell maturation GO:0048469 144 0.019
negative regulation of gene expression GO:0010629 387 0.019
establishment of localization in cell GO:0051649 402 0.019
regulation of phosphorylation GO:0042325 147 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
vesicle mediated transport GO:0016192 381 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
regulation of cell development GO:0060284 215 0.018
small molecule metabolic process GO:0044281 305 0.018
proteolysis GO:0006508 192 0.018
regulation of synapse organization GO:0050807 110 0.018
eye morphogenesis GO:0048592 260 0.018
response to bacterium GO:0009617 198 0.018
response to other organism GO:0051707 293 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
tissue morphogenesis GO:0048729 297 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.018
regulation of localization GO:0032879 275 0.017
peptide metabolic process GO:0006518 80 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
ethanolamine containing compound metabolic process GO:0042439 4 0.017
regulation of cell death GO:0010941 173 0.017
response to lipopolysaccharide GO:0032496 4 0.017
cellular catabolic process GO:0044248 372 0.017
segmentation GO:0035282 207 0.017
organelle assembly GO:0070925 198 0.017
embryonic pattern specification GO:0009880 174 0.017
wound healing GO:0042060 75 0.017
regulation of cell differentiation GO:0045595 302 0.017
single organism cellular localization GO:1902580 180 0.017
regulation of transport GO:0051049 181 0.017
regulation of cellular component biogenesis GO:0044087 201 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
response to biotic stimulus GO:0009607 294 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
detection of chemical stimulus GO:0009593 93 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
cholesterol homeostasis GO:0042632 3 0.016
sensory organ morphogenesis GO:0090596 260 0.016
negative regulation of synapse assembly GO:0051964 39 0.016
connective tissue development GO:0061448 3 0.016
anterior posterior pattern specification GO:0009952 136 0.016
blastoderm segmentation GO:0007350 159 0.016
cilium morphogenesis GO:0060271 39 0.016
cellular amide metabolic process GO:0043603 80 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
jnk cascade GO:0007254 50 0.016
single organism behavior GO:0044708 391 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
sensory perception GO:0007600 196 0.015
organic substance transport GO:0071702 257 0.015
cellular protein localization GO:0034613 160 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
regionalization GO:0003002 416 0.015
amine metabolic process GO:0009308 12 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
eye development GO:0001654 323 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
protein transport GO:0015031 155 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
establishment of protein localization GO:0045184 163 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
intracellular transport GO:0046907 228 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
spermatogenesis GO:0007283 200 0.015
regulation of cellular response to stress GO:0080135 89 0.015
leg disc development GO:0035218 92 0.014
organic substance catabolic process GO:1901575 308 0.014
stress activated mapk cascade GO:0051403 52 0.014
central nervous system development GO:0007417 201 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
cell motility GO:0048870 251 0.014
phagocytosis GO:0006909 215 0.014
endocytosis GO:0006897 310 0.014
mapk cascade GO:0000165 107 0.014
cellular amine metabolic process GO:0044106 12 0.014
dna endoreduplication GO:0042023 22 0.014
actin filament based process GO:0030029 220 0.014
regulation of jnk cascade GO:0046328 40 0.014
response to starvation GO:0042594 97 0.014
macromolecular complex assembly GO:0065003 256 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
regulation of organelle organization GO:0033043 196 0.014
regulation of microtubule based process GO:0032886 49 0.014
response to nutrient levels GO:0031667 114 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.013
alditol phosphate metabolic process GO:0052646 2 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
centrosome cycle GO:0007098 137 0.013
chromatin modification GO:0016568 147 0.013
anterior posterior axis specification GO:0009948 109 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
response to external biotic stimulus GO:0043207 293 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
neuron projection guidance GO:0097485 241 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
adult behavior GO:0030534 137 0.013
single organism intracellular transport GO:1902582 207 0.013
localization of cell GO:0051674 257 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
response to radiation GO:0009314 155 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
male gamete generation GO:0048232 201 0.013
positive regulation of cell motility GO:2000147 3 0.013
embryonic axis specification GO:0000578 107 0.013
antimicrobial humoral response GO:0019730 99 0.013
lateral inhibition GO:0046331 206 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
epithelial cell development GO:0002064 274 0.013
homeostatic process GO:0042592 199 0.013
regulation of mapk cascade GO:0043408 92 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
response to peptide hormone GO:0043434 29 0.013
mesenchymal cell development GO:0014031 1 0.013
carbohydrate metabolic process GO:0005975 82 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
ras protein signal transduction GO:0007265 88 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
detection of stimulus GO:0051606 156 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
macromolecule catabolic process GO:0009057 161 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of molecular function GO:0065009 217 0.012
positive regulation of cell migration GO:0030335 2 0.012
defense response to other organism GO:0098542 225 0.012
regulation of catalytic activity GO:0050790 185 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
hindbrain development GO:0030902 2 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
catabolic process GO:0009056 409 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
purine containing compound metabolic process GO:0072521 155 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
axis specification GO:0009798 167 0.012
regulation of defense response GO:0031347 102 0.012
protein complex biogenesis GO:0070271 201 0.012
cilium organization GO:0044782 41 0.012
photoreceptor cell development GO:0042461 96 0.012
regulation of embryonic development GO:0045995 68 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
single organism catabolic process GO:0044712 228 0.012
telencephalon development GO:0021537 2 0.012
dna replication GO:0006260 48 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
axonogenesis GO:0007409 290 0.012
regulation of multi organism process GO:0043900 131 0.012
oxoacid metabolic process GO:0043436 103 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
leg disc morphogenesis GO:0007478 80 0.011
sterol homeostasis GO:0055092 4 0.011
head development GO:0060322 135 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
limb development GO:0060173 1 0.011
cellular response to insulin stimulus GO:0032869 28 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
chemotaxis GO:0006935 249 0.011
response to extracellular stimulus GO:0009991 116 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
imaginal disc pattern formation GO:0007447 91 0.011
determination of adult lifespan GO:0008340 137 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
notch signaling pathway GO:0007219 120 0.011
axon development GO:0061564 297 0.011
cellular response to organonitrogen compound GO:0071417 36 0.011
positive regulation of transport GO:0051050 92 0.011
tripartite regional subdivision GO:0007351 103 0.011
regulation of protein localization GO:0032880 76 0.011
exocrine system development GO:0035272 162 0.011
response to organophosphorus GO:0046683 2 0.011
developmental programmed cell death GO:0010623 138 0.011
circadian rhythm GO:0007623 105 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of innate immune response GO:0045088 71 0.011
protein complex assembly GO:0006461 200 0.011
ion transport GO:0006811 145 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
regulation of catabolic process GO:0009894 170 0.011
protein localization to organelle GO:0033365 82 0.011
spindle organization GO:0007051 253 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
kidney development GO:0001822 3 0.011
organic acid metabolic process GO:0006082 103 0.011
regulation of cell shape GO:0008360 113 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
wnt signaling pathway GO:0016055 98 0.011
cellular response to peptide GO:1901653 28 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
regulation of protein metabolic process GO:0051246 256 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
cellular protein catabolic process GO:0044257 83 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
protein phosphorylation GO:0006468 169 0.010
cell migration GO:0016477 238 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
salivary gland morphogenesis GO:0007435 145 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
response to organic cyclic compound GO:0014070 89 0.010
axon guidance GO:0007411 233 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
response to wounding GO:0009611 94 0.010
establishment of planar polarity GO:0001736 87 0.010
stem cell differentiation GO:0048863 117 0.010
cyclic nucleotide biosynthetic process GO:0009190 25 0.010
regulation of immune response GO:0050776 118 0.010

CG4221 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.019
nervous system disease DOID:863 0 0.015