Drosophila melanogaster

22 known processes

GstE5 (Dmel_CG17527)

Glutathione S transferase E5

(Aliases: DmGSTE5,Dmel\CG17527,CG17527,GSTE5)

GstE5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutathione metabolic process GO:0006749 37 0.534
cellular modified amino acid metabolic process GO:0006575 45 0.411
peptide metabolic process GO:0006518 80 0.162
small molecule metabolic process GO:0044281 305 0.156
oxoacid metabolic process GO:0043436 103 0.151
response to abiotic stimulus GO:0009628 341 0.151
Fly
carboxylic acid metabolic process GO:0019752 92 0.139
organic acid metabolic process GO:0006082 103 0.131
cellular amide metabolic process GO:0043603 80 0.129
organonitrogen compound metabolic process GO:1901564 318 0.123
polyol biosynthetic process GO:0046173 3 0.120
response to temperature stimulus GO:0009266 106 0.104
Fly
sulfur compound metabolic process GO:0006790 59 0.088
xenobiotic catabolic process GO:0042178 1 0.083
cellular amino acid metabolic process GO:0006520 61 0.074
anion homeostasis GO:0055081 3 0.057
vitamin biosynthetic process GO:0009110 1 0.050
response to organic substance GO:0010033 284 0.049
lauric acid metabolic process GO:0048252 1 0.048
steroid catabolic process GO:0006706 1 0.047
cellular lipid metabolic process GO:0044255 83 0.043
cellular catabolic process GO:0044248 372 0.041
regulation of localization GO:0032879 275 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
organic hydroxy compound metabolic process GO:1901615 83 0.039
organic substance catabolic process GO:1901575 308 0.037
toxin catabolic process GO:0009407 1 0.036
protein modification process GO:0036211 438 0.036
single organism biosynthetic process GO:0044711 206 0.036
catabolic process GO:0009056 409 0.036
response to radiation GO:0009314 155 0.035
multicellular organismal aging GO:0010259 140 0.035
vesicle mediated transport GO:0016192 381 0.034
taxis GO:0042330 304 0.034
ethanolamine containing compound metabolic process GO:0042439 4 0.034
fat soluble vitamin metabolic process GO:0006775 1 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
response to organophosphorus GO:0046683 2 0.033
cellular protein modification process GO:0006464 438 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
response to external biotic stimulus GO:0043207 293 0.033
epithelial cell development GO:0002064 274 0.033
imaginal disc derived appendage development GO:0048737 399 0.033
wing disc morphogenesis GO:0007472 344 0.032
appendage morphogenesis GO:0035107 397 0.032
lipid metabolic process GO:0006629 121 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
fat soluble vitamin biosynthetic process GO:0042362 1 0.031
aggressive behavior GO:0002118 63 0.031
insecticide catabolic process GO:0046701 1 0.031
cellular ketone metabolic process GO:0042180 24 0.030
secondary metabolite catabolic process GO:0090487 1 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
vitamin metabolic process GO:0006766 2 0.030
response to mercury ion GO:0046689 3 0.029
response to other organism GO:0051707 293 0.029
endocytosis GO:0006897 310 0.029
response to biotic stimulus GO:0009607 294 0.029
epithelial cell differentiation GO:0030855 322 0.028
regulation of transport GO:0051049 181 0.028
positive regulation of gene expression GO:0010628 290 0.028
organic substance transport GO:0071702 257 0.028
insecticide metabolic process GO:0017143 2 0.027
cell migration GO:0016477 238 0.027
cellular homeostasis GO:0019725 80 0.027
regionalization GO:0003002 416 0.027
response to oxygen containing compound GO:1901700 200 0.027
regulation of intracellular signal transduction GO:1902531 236 0.026
appendage development GO:0048736 401 0.026
ovarian follicle cell development GO:0030707 248 0.026
defense response GO:0006952 300 0.026
response to lipopolysaccharide GO:0032496 4 0.025
response to heat GO:0009408 63 0.025
Fly
androgen metabolic process GO:0008209 1 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
central nervous system development GO:0007417 201 0.024
organelle fission GO:0048285 340 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
cellular amine metabolic process GO:0044106 12 0.024
kidney development GO:0001822 3 0.024
multi organism behavior GO:0051705 175 0.024
medium chain fatty acid metabolic process GO:0051791 1 0.024
cell death GO:0008219 279 0.024
single organism catabolic process GO:0044712 228 0.024
body morphogenesis GO:0010171 2 0.023
neuron projection guidance GO:0097485 241 0.023
cell proliferation GO:0008283 299 0.023
response to bacterium GO:0009617 198 0.023
localization of cell GO:0051674 257 0.023
response to light stimulus GO:0009416 124 0.022
response to extracellular stimulus GO:0009991 116 0.022
axon development GO:0061564 297 0.022
forebrain development GO:0030900 2 0.022
developmental growth GO:0048589 280 0.022
estrogen metabolic process GO:0008210 1 0.021
chemotaxis GO:0006935 249 0.021
sensory perception GO:0007600 196 0.021
nuclear division GO:0000280 332 0.021
ketone biosynthetic process GO:0042181 16 0.021
epithelium migration GO:0090132 148 0.021
ameboidal type cell migration GO:0001667 151 0.021
amine metabolic process GO:0009308 12 0.021
axon guidance GO:0007411 233 0.021
phagocytosis GO:0006909 215 0.021
phosphorylation GO:0016310 294 0.021
homeostatic process GO:0042592 199 0.021
transmembrane transport GO:0055085 139 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
determination of adult lifespan GO:0008340 137 0.020
cell motility GO:0048870 251 0.020
single organism behavior GO:0044708 391 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
neuron recognition GO:0008038 101 0.020
organophosphate metabolic process GO:0019637 195 0.020
regulation of molecular function GO:0065009 217 0.020
neurological system process GO:0050877 358 0.020
positive regulation of cell communication GO:0010647 250 0.020
axonogenesis GO:0007409 290 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
chaeta development GO:0022416 97 0.019
hormone catabolic process GO:0042447 3 0.019
macromolecular complex assembly GO:0065003 256 0.019
lipid biosynthetic process GO:0008610 46 0.019
chemical homeostasis GO:0048878 92 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
aging GO:0007568 143 0.019
positive regulation of cell motility GO:2000147 3 0.019
triglyceride biosynthetic process GO:0019432 2 0.019
defense response to bacterium GO:0042742 178 0.019
negative regulation of gene expression GO:0010629 387 0.019
mating GO:0007618 120 0.019
secondary metabolic process GO:0019748 75 0.019
regulation of cell cycle GO:0051726 291 0.018
toxin metabolic process GO:0009404 2 0.018
growth GO:0040007 359 0.018
death GO:0016265 284 0.018
immune response GO:0006955 246 0.018
positive regulation of signaling GO:0023056 243 0.018
detection of stimulus GO:0051606 156 0.018
response to nitrogen compound GO:1901698 90 0.018
establishment of localization in cell GO:0051649 402 0.018
telencephalon development GO:0021537 2 0.018
response to monosaccharide GO:0034284 4 0.017
regulation of anatomical structure size GO:0090066 163 0.017
protein complex biogenesis GO:0070271 201 0.017
sterol homeostasis GO:0055092 4 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
aromatic compound catabolic process GO:0019439 166 0.016
cellular response to ethanol GO:0071361 4 0.016
compound eye development GO:0048749 307 0.016
meiotic cell cycle process GO:1903046 132 0.016
negative regulation of signal transduction GO:0009968 206 0.016
cuticle development GO:0042335 86 0.016
chromosome segregation GO:0007059 157 0.016
negative regulation of cell communication GO:0010648 223 0.016
epithelial cell migration GO:0010631 148 0.016
response to nutrient levels GO:0031667 114 0.016
intracellular signal transduction GO:0035556 300 0.016
adult behavior GO:0030534 137 0.016
immune system process GO:0002376 347 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
heterocycle catabolic process GO:0046700 166 0.016
positive regulation of signal transduction GO:0009967 223 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
morphogenesis of an epithelium GO:0002009 276 0.015
ecdysteroid metabolic process GO:0045455 19 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
positive regulation of cell migration GO:0030335 2 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
protein phosphorylation GO:0006468 169 0.015
open tracheal system development GO:0007424 204 0.015
neutral lipid biosynthetic process GO:0046460 2 0.015
rna processing GO:0006396 147 0.015
tube development GO:0035295 244 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
regulation of growth GO:0040008 233 0.015
response to organonitrogen compound GO:0010243 75 0.015
actin cytoskeleton organization GO:0030036 206 0.015
cellular response to organic substance GO:0071310 132 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
maintenance of location GO:0051235 73 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
mating behavior GO:0007617 106 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of protein metabolic process GO:0051246 256 0.015
tissue migration GO:0090130 155 0.015
protein complex assembly GO:0006461 200 0.015
tissue morphogenesis GO:0048729 297 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.014
sensory perception of smell GO:0007608 80 0.014
regulation of response to stress GO:0080134 200 0.014
camera type eye development GO:0043010 4 0.014
response to alcohol GO:0097305 95 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
biological adhesion GO:0022610 138 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
amine catabolic process GO:0009310 1 0.014
regulation of developmental growth GO:0048638 174 0.014
respiratory system development GO:0060541 213 0.014
actin filament based process GO:0030029 220 0.014
protein localization GO:0008104 284 0.014
segmentation GO:0035282 207 0.014
connective tissue development GO:0061448 3 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
regulation of catalytic activity GO:0050790 185 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
chromosome organization GO:0051276 360 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
regulation of hormone levels GO:0010817 40 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
response to glucose GO:0009749 2 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
regulation of cellular localization GO:0060341 136 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
gland development GO:0048732 191 0.014
cellular macromolecule localization GO:0070727 220 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
cell cycle phase transition GO:0044770 140 0.013
ras protein signal transduction GO:0007265 88 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
response to endogenous stimulus GO:0009719 119 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
single organism intracellular transport GO:1902582 207 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
positive regulation of molecular function GO:0044093 136 0.013
ovarian follicle cell migration GO:0007297 121 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
cell recognition GO:0008037 102 0.013
response to hexose GO:0009746 3 0.013
programmed cell death GO:0012501 257 0.013
pigmentation GO:0043473 75 0.013
male gamete generation GO:0048232 201 0.013
phosphatidylethanolamine metabolic process GO:0046337 1 0.013
oxidation reduction process GO:0055114 123 0.013
single organism cellular localization GO:1902580 180 0.013
developmental maturation GO:0021700 172 0.013
nucleotide metabolic process GO:0009117 161 0.013
actin filament organization GO:0007015 126 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
protein transport GO:0015031 155 0.013
cell adhesion GO:0007155 136 0.013
intracellular transport GO:0046907 228 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
eye pigment biosynthetic process GO:0006726 32 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
synaptic target recognition GO:0008039 45 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
ion homeostasis GO:0050801 55 0.013
regulation of catabolic process GO:0009894 170 0.013
lipid storage GO:0019915 38 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
small molecule biosynthetic process GO:0044283 37 0.013
cellular response to high light intensity GO:0071486 1 0.013
spindle organization GO:0007051 253 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
cytoplasmic transport GO:0016482 130 0.012
acetylcholine metabolic process GO:0008291 2 0.012
negative regulation of developmental process GO:0051093 201 0.012
regulation of lipid transport GO:0032368 3 0.012
proteolysis GO:0006508 192 0.012
compound eye morphogenesis GO:0001745 249 0.012
carbohydrate metabolic process GO:0005975 82 0.012
spermatogenesis GO:0007283 200 0.012
border follicle cell migration GO:0007298 113 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
regulation of phosphorylation GO:0042325 147 0.012
wnt signaling pathway GO:0016055 98 0.012
positive regulation of lipid storage GO:0010884 4 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
response to copper ion GO:0046688 4 0.012
glycerolipid catabolic process GO:0046503 3 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
immune response activating signal transduction GO:0002757 2 0.012
positive regulation of sequestering of triglyceride GO:0010890 1 0.012
negative regulation of signaling GO:0023057 219 0.012
eye morphogenesis GO:0048592 260 0.012
establishment of protein localization GO:0045184 163 0.012
choline metabolic process GO:0019695 1 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
positive regulation of transport GO:0051050 92 0.012
organophosphate catabolic process GO:0046434 112 0.012
eye development GO:0001654 323 0.012
hormone metabolic process GO:0042445 33 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
cation transport GO:0006812 110 0.012
multi organism reproductive behavior GO:0044705 121 0.012
cellular protein localization GO:0034613 160 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
ion transport GO:0006811 145 0.012
triglyceride catabolic process GO:0019433 3 0.012
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.012
macromolecule catabolic process GO:0009057 161 0.011
dna metabolic process GO:0006259 227 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
regulation of cell proliferation GO:0042127 163 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
mrna processing GO:0006397 104 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
jak stat cascade GO:0007259 49 0.011
nucleoside metabolic process GO:0009116 127 0.011
acetylcholine catabolic process GO:0006581 1 0.011
lateral inhibition GO:0046331 206 0.011
establishment of tissue polarity GO:0007164 87 0.011
cell projection assembly GO:0030031 94 0.011
innate immune response GO:0045087 144 0.011
regulation of cell death GO:0010941 173 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of immune response GO:0050776 118 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
intracellular protein transport GO:0006886 104 0.011
endomembrane system organization GO:0010256 119 0.011
cellular biogenic amine catabolic process GO:0042402 1 0.011
acetate ester metabolic process GO:1900619 2 0.011
regulation of cell differentiation GO:0045595 302 0.011
choline catabolic process GO:0042426 1 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
purine containing compound metabolic process GO:0072521 155 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
activation of innate immune response GO:0002218 4 0.011
regulation of lipid storage GO:0010883 22 0.011
regulation of multi organism process GO:0043900 131 0.011
mitotic nuclear division GO:0007067 213 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
wound healing GO:0042060 75 0.010
cellularization GO:0007349 90 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
meiotic nuclear division GO:0007126 151 0.010
response to ketone GO:1901654 34 0.010
head development GO:0060322 135 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
nucleotide catabolic process GO:0009166 109 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
cellular response to radiation GO:0071478 52 0.010
cholesterol homeostasis GO:0042632 3 0.010
brain development GO:0007420 120 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
limb development GO:0060173 1 0.010
neurotransmitter catabolic process GO:0042135 1 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
embryonic pattern specification GO:0009880 174 0.010
negative regulation of cell death GO:0060548 81 0.010
response to alkaloid GO:0043279 26 0.010
motor neuron axon guidance GO:0008045 58 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
mapk cascade GO:0000165 107 0.010
cellular response to hexose stimulus GO:0071331 1 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
axis specification GO:0009798 167 0.010
detection of abiotic stimulus GO:0009582 66 0.010
spermatid differentiation GO:0048515 114 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
pattern recognition receptor signaling pathway GO:0002221 2 0.010
response to wounding GO:0009611 94 0.010
response to ethanol GO:0045471 59 0.010

GstE5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
cardiovascular system disease DOID:1287 0 0.040
vascular disease DOID:178 0 0.040
artery disease DOID:0050828 0 0.040
hypertension DOID:10763 0 0.040
essential hypertension DOID:10825 0 0.025
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.010
disease of cellular proliferation DOID:14566 0 0.010