Drosophila melanogaster

41 known processes

SF1 (Dmel_CG5836)

Splicing factor 1

(Aliases: cg5836,Dmel\CG5836,CG5836,p70,dSF1)

SF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell proliferation GO:0008283 299 0.488
Rat
intracellular signal transduction GO:0035556 300 0.464
negative regulation of rna metabolic process GO:0051253 251 0.437
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.406
regulation of intracellular signal transduction GO:1902531 236 0.356
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.328
regulation of mrna splicing via spliceosome GO:0048024 64 0.321
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.291
positive regulation of cellular biosynthetic process GO:0031328 316 0.247
positive regulation of rna metabolic process GO:0051254 271 0.217
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.211
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.196
negative regulation of biosynthetic process GO:0009890 277 0.176
protein modification process GO:0036211 438 0.173
spindle organization GO:0007051 253 0.170
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.161
mitotic spindle organization GO:0007052 220 0.157
protein dna complex assembly GO:0065004 63 0.151
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.143
negative regulation of cellular metabolic process GO:0031324 382 0.143
transcription from rna polymerase ii promoter GO:0006366 368 0.143
leg disc morphogenesis GO:0007478 80 0.140
signal transduction by phosphorylation GO:0023014 107 0.134
nucleosome organization GO:0034728 59 0.133
negative regulation of cellular biosynthetic process GO:0031327 277 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.121
positive regulation of gene expression GO:0010628 290 0.120
negative regulation of gene expression GO:0010629 387 0.118
ras protein signal transduction GO:0007265 88 0.117
chromatin organization GO:0006325 207 0.116
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.116
mrna metabolic process GO:0016071 124 0.116
regulation of cell cycle GO:0051726 291 0.109
protein dna complex subunit organization GO:0071824 86 0.109
positive regulation of rna biosynthetic process GO:1902680 266 0.105
positive regulation of signaling GO:0023056 243 0.104
positive regulation of macromolecule metabolic process GO:0010604 405 0.104
chromosome organization GO:0051276 360 0.104
mapk cascade GO:0000165 107 0.101
mrna processing GO:0006397 104 0.101
regulation of cell cycle process GO:0010564 181 0.100
imaginal disc derived appendage development GO:0048737 399 0.099
post embryonic appendage morphogenesis GO:0035120 385 0.099
regulation of mapk cascade GO:0043408 92 0.098
positive regulation of nucleic acid templated transcription GO:1903508 266 0.097
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.095
positive regulation of biosynthetic process GO:0009891 316 0.094
positive regulation of transcription dna templated GO:0045893 266 0.094
head development GO:0060322 135 0.092
positive regulation of signal transduction GO:0009967 223 0.092
regulation of small gtpase mediated signal transduction GO:0051056 93 0.090
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.088
imaginal disc derived leg morphogenesis GO:0007480 80 0.087
appendage development GO:0048736 401 0.085
developmental growth GO:0048589 280 0.085
positive regulation of intracellular signal transduction GO:1902533 116 0.084
regulation of phosphorus metabolic process GO:0051174 210 0.083
chromatin remodeling GO:0006338 72 0.083
inter male aggressive behavior GO:0002121 60 0.080
erk1 and erk2 cascade GO:0070371 39 0.080
regulation of mrna metabolic process GO:1903311 72 0.079
regulation of mrna processing GO:0050684 71 0.079
immune system process GO:0002376 347 0.078
alternative mrna splicing via spliceosome GO:0000380 60 0.078
rna splicing via transesterification reactions GO:0000375 73 0.076
positive regulation of phosphate metabolic process GO:0045937 139 0.072
regulation of cell proliferation GO:0042127 163 0.071
Rat
negative regulation of signal transduction GO:0009968 206 0.070
regulation of phosphate metabolic process GO:0019220 210 0.070
cellular protein modification process GO:0006464 438 0.065
dendrite development GO:0016358 204 0.064
multi organism behavior GO:0051705 175 0.063
regulation of cellular response to stress GO:0080135 89 0.062
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.061
positive regulation of response to stimulus GO:0048584 323 0.061
compound eye development GO:0048749 307 0.060
regulation of rna splicing GO:0043484 69 0.057
leg disc development GO:0035218 92 0.057
covalent chromatin modification GO:0016569 106 0.057
regulation of phosphorylation GO:0042325 147 0.056
positive regulation of phosphorus metabolic process GO:0010562 139 0.056
rna splicing GO:0008380 83 0.055
axon development GO:0061564 297 0.053
regulation of response to stress GO:0080134 200 0.053
axonogenesis GO:0007409 290 0.052
small gtpase mediated signal transduction GO:0007264 88 0.052
histone mrna metabolic process GO:0008334 8 0.052
dendrite morphogenesis GO:0048813 199 0.052
phosphorylation GO:0016310 294 0.051
organophosphate metabolic process GO:0019637 195 0.050
positive regulation of mapk cascade GO:0043410 63 0.048
wing disc morphogenesis GO:0007472 344 0.048
biological adhesion GO:0022610 138 0.047
central nervous system development GO:0007417 201 0.047
positive regulation of developmental process GO:0051094 143 0.046
regulation of molecular function GO:0065009 217 0.045
internal protein amino acid acetylation GO:0006475 38 0.045
nuclear division GO:0000280 332 0.044
regulation of multicellular organismal development GO:2000026 414 0.044
negative regulation of transcription dna templated GO:0045892 237 0.043
regulation of neuron projection development GO:0010975 69 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.043
chromosome segregation GO:0007059 157 0.042
regulation of multi organism process GO:0043900 131 0.042
regulation of neurogenesis GO:0050767 158 0.040
single organism behavior GO:0044708 391 0.039
negative regulation of response to stimulus GO:0048585 258 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
macromolecule methylation GO:0043414 45 0.038
regionalization GO:0003002 416 0.038
chromatin modification GO:0016568 147 0.037
cell cycle phase transition GO:0044770 140 0.037
organonitrogen compound metabolic process GO:1901564 318 0.036
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.036
regulation of catalytic activity GO:0050790 185 0.035
aging GO:0007568 143 0.034
regulation of erk1 and erk2 cascade GO:0070372 39 0.033
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.033
negative regulation of rna biosynthetic process GO:1902679 240 0.033
regulation of ras protein signal transduction GO:0046578 93 0.032
organic substance transport GO:0071702 257 0.032
regulation of localization GO:0032879 275 0.032
cellular component disassembly GO:0022411 46 0.031
embryo development ending in birth or egg hatching GO:0009792 152 0.031
purine containing compound metabolic process GO:0072521 155 0.031
macromolecular complex assembly GO:0065003 256 0.031
positive regulation of phosphorylation GO:0042327 87 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
body morphogenesis GO:0010171 2 0.030
ribonucleoside triphosphate catabolic process GO:0009203 108 0.030
gland development GO:0048732 191 0.029
neuroblast proliferation GO:0007405 74 0.029
mitotic cell cycle phase transition GO:0044772 138 0.029
endocytosis GO:0006897 310 0.029
methylation GO:0032259 47 0.028
rna processing GO:0006396 147 0.028
organelle fission GO:0048285 340 0.027
embryonic pattern specification GO:0009880 174 0.027
positive regulation of cell communication GO:0010647 250 0.027
negative regulation of signaling GO:0023057 219 0.027
muscle structure development GO:0061061 224 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
regulation of growth GO:0040008 233 0.026
purine nucleotide metabolic process GO:0006163 146 0.025
response to endogenous stimulus GO:0009719 119 0.025
cell division GO:0051301 248 0.025
dna metabolic process GO:0006259 227 0.024
regulation of neuron differentiation GO:0045664 103 0.024
eye development GO:0001654 323 0.024
actin cytoskeleton organization GO:0030036 206 0.024
histone modification GO:0016570 106 0.024
morphogenesis of an epithelium GO:0002009 276 0.023
single organism catabolic process GO:0044712 228 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
mitotic nuclear division GO:0007067 213 0.023
meiotic nuclear division GO:0007126 151 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
respiratory system development GO:0060541 213 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
peptidyl lysine acetylation GO:0018394 39 0.022
protein complex biogenesis GO:0070271 201 0.022
tube development GO:0035295 244 0.022
phagocytosis GO:0006909 215 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
regulation of chromosome organization GO:0033044 64 0.021
small molecule metabolic process GO:0044281 305 0.021
immune system development GO:0002520 57 0.021
peptidyl amino acid modification GO:0018193 105 0.021
catabolic process GO:0009056 409 0.021
mitotic sister chromatid segregation GO:0000070 87 0.020
gene silencing GO:0016458 138 0.020
signal transduction in response to dna damage GO:0042770 3 0.020
appendage morphogenesis GO:0035107 397 0.020
regulation of chromatin modification GO:1903308 28 0.019
forebrain development GO:0030900 2 0.019
epithelial cell differentiation GO:0030855 322 0.019
regulation of organelle organization GO:0033043 196 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
cell cycle dna replication GO:0044786 23 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.019
single organism cell adhesion GO:0098602 47 0.019
carbohydrate metabolic process GO:0005975 82 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
multicellular organismal aging GO:0010259 140 0.018
chemosensory behavior GO:0007635 106 0.018
growth GO:0040007 359 0.018
histone acetylation GO:0016573 38 0.018
positive regulation of catalytic activity GO:0043085 118 0.017
regulation of protein deacetylation GO:0090311 2 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
stem cell maintenance GO:0019827 67 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
protein complex assembly GO:0006461 200 0.017
nucleotide metabolic process GO:0009117 161 0.016
regulation of response to dna damage stimulus GO:2001020 23 0.016
limb morphogenesis GO:0035108 1 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
jak stat cascade GO:0007259 49 0.016
death GO:0016265 284 0.016
negative regulation of molecular function GO:0044092 51 0.016
dna templated transcription elongation GO:0006354 18 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
brain development GO:0007420 120 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
hematopoietic or lymphoid organ development GO:0048534 57 0.015
positive regulation of ras protein signal transduction GO:0046579 43 0.015
atp dependent chromatin remodeling GO:0043044 22 0.015
nucleoside catabolic process GO:0009164 112 0.015
regulation of cell differentiation GO:0045595 302 0.015
peptidyl lysine modification GO:0018205 57 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
humoral immune response GO:0006959 117 0.015
centrosome organization GO:0051297 163 0.015
sister chromatid segregation GO:0000819 92 0.015
regulation of circadian rhythm GO:0042752 49 0.015
protein acetylation GO:0006473 39 0.015
meiotic cell cycle GO:0051321 171 0.015
regulation of immune system process GO:0002682 176 0.014
organic substance catabolic process GO:1901575 308 0.014
dephosphorylation GO:0016311 51 0.014
dna integrity checkpoint GO:0031570 81 0.014
actin filament based process GO:0030029 220 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
neuron projection guidance GO:0097485 241 0.014
embryonic hindgut morphogenesis GO:0048619 48 0.014
organophosphate catabolic process GO:0046434 112 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
histone deacetylation GO:0016575 9 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
positive regulation of organelle organization GO:0010638 65 0.013
regulation of protein modification process GO:0031399 112 0.013
segmentation GO:0035282 207 0.013
cytoplasmic transport GO:0016482 130 0.013
multicellular organism growth GO:0035264 46 0.013
meiotic cytokinesis GO:0033206 33 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
single organism biosynthetic process GO:0044711 206 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
regulation of chromatin organization GO:1902275 32 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of nervous system development GO:0051960 248 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
vesicle mediated transport GO:0016192 381 0.012
negative regulation of nervous system development GO:0051961 92 0.012
egg activation GO:0007343 9 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of cell shape GO:0008360 113 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
amine metabolic process GO:0009308 12 0.011
spliceosomal complex assembly GO:0000245 1 0.011
spindle assembly GO:0051225 80 0.011
somatic muscle development GO:0007525 66 0.011
regulation of cell division GO:0051302 72 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
positive regulation of catabolic process GO:0009896 105 0.011
reproductive behavior GO:0019098 122 0.011
programmed cell death GO:0012501 257 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
axon guidance GO:0007411 233 0.011
olfactory behavior GO:0042048 97 0.011
tissue morphogenesis GO:0048729 297 0.011
muscle cell differentiation GO:0042692 103 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cell death GO:0008219 279 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
epithelial cell development GO:0002064 274 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
protein complex disassembly GO:0043241 36 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
cell adhesion GO:0007155 136 0.010
cellular response to hormone stimulus GO:0032870 44 0.010
regulation of gene silencing GO:0060968 63 0.010
regulation of map kinase activity GO:0043405 17 0.010
cell fate specification GO:0001708 71 0.010
establishment of spindle orientation GO:0051294 18 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
positive regulation of molecular function GO:0044093 136 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
mrna splice site selection GO:0006376 1 0.010

SF1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
nervous system disease DOID:863 0 0.011