Drosophila melanogaster

49 known processes

bmm (Dmel_CG5295)

brummer

(Aliases: Dmel\CG5295,CG5295,Atgl,Bmm)

bmm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.588
lipid homeostasis GO:0055088 33 0.503
multicellular organismal aging GO:0010259 140 0.386
lipid metabolic process GO:0006629 121 0.318
aging GO:0007568 143 0.266
behavioral response to ethanol GO:0048149 49 0.258
acylglycerol homeostasis GO:0055090 19 0.170
triglyceride homeostasis GO:0070328 18 0.151
response to oxidative stress GO:0006979 86 0.137
cellular response to ethanol GO:0071361 4 0.129
oxoacid metabolic process GO:0043436 103 0.123
appendage morphogenesis GO:0035107 397 0.121
positive regulation of transcription dna templated GO:0045893 266 0.096
triglyceride metabolic process GO:0006641 12 0.095
establishment of localization in cell GO:0051649 402 0.093
post embryonic appendage morphogenesis GO:0035120 385 0.087
neutral lipid biosynthetic process GO:0046460 2 0.084
Human
appendage development GO:0048736 401 0.082
small molecule metabolic process GO:0044281 305 0.080
positive regulation of rna biosynthetic process GO:1902680 266 0.079
single organism intracellular transport GO:1902582 207 0.078
response to organic substance GO:0010033 284 0.077
adult behavior GO:0030534 137 0.076
anion homeostasis GO:0055081 3 0.075
sterol homeostasis GO:0055092 4 0.073
cholesterol homeostasis GO:0042632 3 0.072
organic acid metabolic process GO:0006082 103 0.071
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.070
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
chemical homeostasis GO:0048878 92 0.067
wing disc morphogenesis GO:0007472 344 0.067
cell proliferation GO:0008283 299 0.065
gland development GO:0048732 191 0.065
phospholipid homeostasis GO:0055091 1 0.065
imaginal disc derived appendage development GO:0048737 399 0.063
developmental programmed cell death GO:0010623 138 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.061
positive regulation of nucleic acid templated transcription GO:1903508 266 0.060
positive regulation of rna metabolic process GO:0051254 271 0.056
death GO:0016265 284 0.056
peptidyl amino acid modification GO:0018193 105 0.055
growth GO:0040007 359 0.055
g protein coupled receptor signaling pathway GO:0007186 136 0.053
acylglycerol biosynthetic process GO:0046463 2 0.053
Human
regulation of cell cycle GO:0051726 291 0.053
response to oxygen containing compound GO:1901700 200 0.051
cellular response to oxygen containing compound GO:1901701 79 0.050
regulation of transport GO:0051049 181 0.050
triglyceride biosynthetic process GO:0019432 2 0.048
Human
response to radiation GO:0009314 155 0.048
cellular amine metabolic process GO:0044106 12 0.048
regulation of cell proliferation GO:0042127 163 0.047
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
organonitrogen compound metabolic process GO:1901564 318 0.046
lipid catabolic process GO:0016042 21 0.045
positive regulation of response to stimulus GO:0048584 323 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.044
carboxylic acid metabolic process GO:0019752 92 0.043
negative regulation of mitotic cell cycle GO:0045930 109 0.043
positive regulation of gene expression GO:0010628 290 0.042
cellular ketone metabolic process GO:0042180 24 0.042
histolysis GO:0007559 102 0.042
lipid modification GO:0030258 24 0.042
transcription from rna polymerase ii promoter GO:0006366 368 0.040
tissue death GO:0016271 102 0.040
negative regulation of multicellular organismal process GO:0051241 142 0.040
oxidation reduction process GO:0055114 123 0.040
organic substance catabolic process GO:1901575 308 0.040
extrinsic apoptotic signaling pathway GO:0097191 1 0.039
regulation of multicellular organismal development GO:2000026 414 0.039
single organism biosynthetic process GO:0044711 206 0.039
Human
mitochondrion organization GO:0007005 65 0.039
response to starvation GO:0042594 97 0.039
lipid biosynthetic process GO:0008610 46 0.038
Human
cellular lipid metabolic process GO:0044255 83 0.038
regulation of growth GO:0040008 233 0.038
protein localization GO:0008104 284 0.038
maintenance of location GO:0051235 73 0.037
regulation of protein transport GO:0051223 57 0.037
phototaxis GO:0042331 21 0.037
response to monosaccharide GO:0034284 4 0.037
regulation of molecular function GO:0065009 217 0.037
developmental growth GO:0048589 280 0.037
organic substance transport GO:0071702 257 0.036
tissue morphogenesis GO:0048729 297 0.036
macromolecular complex assembly GO:0065003 256 0.036
negative regulation of growth GO:0045926 84 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
locomotory behavior GO:0007626 176 0.035
hindbrain development GO:0030902 2 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.034
response to extracellular stimulus GO:0009991 116 0.034
response to nitrogen compound GO:1901698 90 0.034
negative regulation of cell proliferation GO:0008285 69 0.034
regulation of mitotic cell cycle GO:0007346 190 0.034
synaptic transmission GO:0007268 288 0.034
regulation of cytoskeleton organization GO:0051493 89 0.034
regulation of protein localization GO:0032880 76 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
protein modification process GO:0036211 438 0.034
cellular macromolecule localization GO:0070727 220 0.034
single organism nuclear import GO:1902593 51 0.033
regulation of intracellular transport GO:0032386 64 0.033
regulation of localization GO:0032879 275 0.033
regulation of intracellular protein transport GO:0033157 46 0.032
positive regulation of lipid metabolic process GO:0045834 4 0.032
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
chromosome segregation GO:0007059 157 0.032
acetaldehyde metabolic process GO:0006117 5 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.032
catabolic process GO:0009056 409 0.032
regulation of lipid storage GO:0010883 22 0.031
cellular response to external stimulus GO:0071496 66 0.031
carbohydrate homeostasis GO:0033500 12 0.030
regulation of microtubule cytoskeleton organization GO:0070507 41 0.030
regulation of catabolic process GO:0009894 170 0.030
Mouse
cellularization GO:0007349 90 0.030
single organism behavior GO:0044708 391 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.029
protein transport GO:0015031 155 0.028
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.028
response to light stimulus GO:0009416 124 0.028
protein localization to organelle GO:0033365 82 0.028
protein complex biogenesis GO:0070271 201 0.028
regulation of protein import into nucleus GO:0042306 28 0.027
leg disc development GO:0035218 92 0.027
chemotaxis GO:0006935 249 0.027
regulation of developmental growth GO:0048638 174 0.027
regulation of cytoplasmic transport GO:1903649 47 0.026
secondary metabolic process GO:0019748 75 0.026
response to organophosphorus GO:0046683 2 0.026
response to alcohol GO:0097305 95 0.026
homeostatic process GO:0042592 199 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
cellular protein localization GO:0034613 160 0.026
regulation of nucleocytoplasmic transport GO:0046822 35 0.026
regulation of protein metabolic process GO:0051246 256 0.026
wnt signaling pathway GO:0016055 98 0.026
cellular response to starvation GO:0009267 61 0.025
cell recognition GO:0008037 102 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
cellular lipid catabolic process GO:0044242 16 0.025
establishment of protein localization GO:0045184 163 0.025
response to hexose GO:0009746 3 0.025
taxis GO:0042330 304 0.025
fatty acid metabolic process GO:0006631 20 0.024
connective tissue development GO:0061448 3 0.024
cellular carbohydrate catabolic process GO:0044275 2 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
response to nutrient levels GO:0031667 114 0.024
ras protein signal transduction GO:0007265 88 0.024
neuron recognition GO:0008038 101 0.024
response to glucose GO:0009749 2 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
cellular response to radiation GO:0071478 52 0.023
defense response GO:0006952 300 0.023
response to abiotic stimulus GO:0009628 341 0.023
vesicle mediated transport GO:0016192 381 0.023
phenol containing compound metabolic process GO:0018958 57 0.023
axon guidance GO:0007411 233 0.023
chromatin remodeling GO:0006338 72 0.023
cell motility GO:0048870 251 0.022
immune effector process GO:0002252 98 0.022
alcohol metabolic process GO:0006066 25 0.022
protein targeting GO:0006605 64 0.022
protein import into nucleus GO:0006606 51 0.022
cytoplasmic transport GO:0016482 130 0.022
protein complex localization GO:0031503 4 0.022
gland morphogenesis GO:0022612 145 0.022
negative regulation of developmental process GO:0051093 201 0.022
spindle organization GO:0007051 253 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
response to ethanol GO:0045471 59 0.021
cellular response to nutrient levels GO:0031669 62 0.021
lipid localization GO:0010876 54 0.021
amine metabolic process GO:0009308 12 0.021
cellular protein modification process GO:0006464 438 0.021
single organism catabolic process GO:0044712 228 0.020
regulation of lipid metabolic process GO:0019216 15 0.020
Mouse
response to organonitrogen compound GO:0010243 75 0.020
stress activated protein kinase signaling cascade GO:0031098 55 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
protein complex assembly GO:0006461 200 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
regulation of lipid transport GO:0032368 3 0.020
intracellular transport GO:0046907 228 0.020
body morphogenesis GO:0010171 2 0.020
negative regulation of response to stimulus GO:0048585 258 0.019
positive regulation of cell migration GO:0030335 2 0.019
ethanolamine containing compound metabolic process GO:0042439 4 0.019
digestive system development GO:0055123 149 0.019
wound healing GO:0042060 75 0.019
neurotransmitter metabolic process GO:0042133 2 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
single organism cellular localization GO:1902580 180 0.019
negative regulation of signaling GO:0023057 219 0.018
pigment metabolic process GO:0042440 84 0.018
salivary gland histolysis GO:0035070 88 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of nf kappab import into nucleus GO:0042345 1 0.018
lipid oxidation GO:0034440 7 0.018
positive regulation of signal transduction GO:0009967 223 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
regulation of organelle organization GO:0033043 196 0.018
cell death GO:0008219 279 0.018
exocrine system development GO:0035272 162 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
cholesterol transport GO:0030301 2 0.018
regulation of establishment of protein localization GO:0070201 61 0.017
programmed cell death GO:0012501 257 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
neutral lipid metabolic process GO:0006638 12 0.017
mitotic spindle organization GO:0007052 220 0.017
nuclear division GO:0000280 332 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
digestive tract development GO:0048565 149 0.017
neuron projection guidance GO:0097485 241 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
regulation of cell differentiation GO:0045595 302 0.017
autophagic cell death GO:0048102 83 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
phosphorylation GO:0016310 294 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
Mouse
jak stat cascade GO:0007259 49 0.016
regulation of anatomical structure size GO:0090066 163 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.016
leg disc morphogenesis GO:0007478 80 0.016
protein import GO:0017038 55 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
nuclear import GO:0051170 51 0.016
negative regulation of cell cycle GO:0045786 116 0.016
peptidyl tyrosine phosphorylation GO:0018108 24 0.016
salivary gland development GO:0007431 162 0.016
nuclear transport GO:0051169 72 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
negative regulation of signal transduction GO:0009968 206 0.016
glycerolipid catabolic process GO:0046503 3 0.015
neuropeptide signaling pathway GO:0007218 45 0.015
gastrulation GO:0007369 70 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.015
negative regulation of cell communication GO:0010648 223 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
tube development GO:0035295 244 0.015
outflow tract morphogenesis GO:0003151 4 0.015
epithelial cell differentiation GO:0030855 322 0.015
protein localization to nucleus GO:0034504 55 0.015
response to lipopolysaccharide GO:0032496 4 0.015
mitotic cytokinesis GO:0000281 50 0.015
salivary gland morphogenesis GO:0007435 145 0.015
pole cell formation GO:0007279 19 0.015
immune system process GO:0002376 347 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.015
defense response to other organism GO:0098542 225 0.015
skin development GO:0043588 65 0.015
response to temperature stimulus GO:0009266 106 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
protein targeting to nucleus GO:0044744 51 0.014
regulation of response to oxidative stress GO:1902882 4 0.014
response to other organism GO:0051707 293 0.014
cellular amide metabolic process GO:0043603 80 0.014
camera type eye development GO:0043010 4 0.014
circadian rhythm GO:0007623 105 0.014
regulation of cell size GO:0008361 63 0.014
endoplasmic reticulum organization GO:0007029 13 0.014
cellular response to organic substance GO:0071310 132 0.014
cell growth GO:0016049 108 0.014
phagocytosis GO:0006909 215 0.014
non sensory hair organization GO:0035316 47 0.014
cellular catabolic process GO:0044248 372 0.014
regulation of steroid metabolic process GO:0019218 2 0.014
endocytosis GO:0006897 310 0.014
positive regulation of cell motility GO:2000147 3 0.014
response to biotic stimulus GO:0009607 294 0.014
regulation of bmp signaling pathway GO:0030510 23 0.014
mesenchymal cell development GO:0014031 1 0.014
neurological system process GO:0050877 358 0.014
regulation of actin cytoskeleton organization GO:0032956 42 0.014
regulation of cell death GO:0010941 173 0.014
regulation of actin filament based process GO:0032970 42 0.014
regulation of stress activated mapk cascade GO:0032872 41 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.013
cell cycle phase transition GO:0044770 140 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
positive regulation of catabolic process GO:0009896 105 0.013
Mouse
hair cell differentiation GO:0035315 47 0.013
regulation of protein localization to nucleus GO:1900180 29 0.013
forebrain development GO:0030900 2 0.013
positive regulation of molecular function GO:0044093 136 0.013
retina development in camera type eye GO:0060041 4 0.013
cardiac cell fate commitment GO:0060911 17 0.013
acylglycerol metabolic process GO:0006639 12 0.013
negative regulation of gene expression GO:0010629 387 0.013
tube morphogenesis GO:0035239 191 0.013
notch signaling pathway GO:0007219 120 0.013
nucleus organization GO:0006997 45 0.013
regulation of sterol transport GO:0032371 1 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
developmental maturation GO:0021700 172 0.012
imaginal disc derived wing hair organization GO:0035317 45 0.012
response to reactive oxygen species GO:0000302 24 0.012
melanotic encapsulation of foreign target GO:0035011 30 0.012
positive regulation of transport GO:0051050 92 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
acylglycerol catabolic process GO:0046464 3 0.012
stem cell proliferation GO:0072089 88 0.012
bmp signaling pathway GO:0030509 27 0.012
spermatogenesis GO:0007283 200 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
energy taxis GO:0009453 21 0.012
central nervous system development GO:0007417 201 0.012
pole cell development GO:0007277 26 0.012
regulation of cell projection organization GO:0031344 92 0.012
cell division GO:0051301 248 0.012
secretion GO:0046903 109 0.012
organelle fission GO:0048285 340 0.012
defense response to bacterium GO:0042742 178 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
regulation of protein targeting GO:1903533 29 0.012
monocarboxylic acid metabolic process GO:0032787 29 0.012
axonogenesis GO:0007409 290 0.012
epidermal cell differentiation GO:0009913 51 0.012
localization of cell GO:0051674 257 0.012
telencephalon development GO:0021537 2 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.011
Mouse
actin filament based process GO:0030029 220 0.011
positive regulation of lipid storage GO:0010884 4 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
cellular response to cadmium ion GO:0071276 6 0.011
stem cell differentiation GO:0048863 117 0.011
mushroom body development GO:0016319 70 0.011
convergent extension GO:0060026 2 0.011
response to heat GO:0009408 63 0.011
acetylcholine metabolic process GO:0008291 2 0.011
regulation of cell cycle process GO:0010564 181 0.011
cardiocyte differentiation GO:0035051 29 0.011
regulation of hydrolase activity GO:0051336 97 0.011
regulation of lipid biosynthetic process GO:0046890 6 0.011
eye morphogenesis GO:0048592 260 0.011
endodermal cell fate commitment GO:0001711 3 0.011
metal ion homeostasis GO:0055065 44 0.011
organelle assembly GO:0070925 198 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
intracellular protein transport GO:0006886 104 0.011
microtubule based movement GO:0007018 51 0.011
neuromuscular synaptic transmission GO:0007274 67 0.011
positive regulation of lipid catabolic process GO:0050996 1 0.011
Mouse
response to trehalose GO:0010353 3 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
positive regulation of lipid biosynthetic process GO:0046889 3 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
regulation of phosphorylation GO:0042325 147 0.011
neural retina development GO:0003407 4 0.011
endomembrane system organization GO:0010256 119 0.011
camera type eye morphogenesis GO:0048593 2 0.011
steroid biosynthetic process GO:0006694 16 0.011
negative regulation of molecular function GO:0044092 51 0.010
generation of precursor metabolites and energy GO:0006091 42 0.010
synaptic target recognition GO:0008039 45 0.010
hindgut morphogenesis GO:0007442 58 0.010
negative regulation of phosphorylation GO:0042326 35 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
positive regulation of cell communication GO:0010647 250 0.010
protein catabolic process GO:0030163 101 0.010
nitrogen compound transport GO:0071705 85 0.010
regulation of sequestering of calcium ion GO:0051282 3 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
cellular carbohydrate metabolic process GO:0044262 22 0.010
response to wounding GO:0009611 94 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
peptidyl tyrosine modification GO:0018212 24 0.010

bmm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
acquired metabolic disease DOID:0060158 0 0.024
artery disease DOID:0050828 0 0.023
disease of anatomical entity DOID:7 0 0.023
vascular disease DOID:178 0 0.023
cardiovascular system disease DOID:1287 0 0.023
carbohydrate metabolism disease DOID:0050013 0 0.018
glucose metabolism disease DOID:4194 0 0.018
diabetes mellitus DOID:9351 0 0.016
type 2 diabetes mellitus DOID:9352 0 0.016
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010