Drosophila melanogaster

34 known processes

mus201 (Dmel_CG10890)

mutagen-sensitive 201

(Aliases: DmXPG,ESTS:55A11T,XPG[DM],XPG[Dm],XPG,55A11T,CG10890,mus-201,Dmel\CG10890,CG32956,xpg/mus201,rad202,mus(2)201)

mus201 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide excision repair GO:0006289 8 0.952
Mouse
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.908
dna repair GO:0006281 54 0.887
dna damage checkpoint GO:0000077 78 0.881
Worm
double strand break repair GO:0006302 26 0.856
Worm
cellular response to dna damage stimulus GO:0006974 223 0.729
dna synthesis involved in dna repair GO:0000731 5 0.728
non recombinational repair GO:0000726 7 0.707
recombinational repair GO:0000725 13 0.677
Worm
dna metabolic process GO:0006259 227 0.642
dna integrity checkpoint GO:0031570 81 0.619
Worm
dna double strand break processing GO:0000729 3 0.605
mitotic dna damage checkpoint GO:0044773 74 0.564
double strand break repair via nonhomologous end joining GO:0006303 5 0.525
g2 dna damage checkpoint GO:0031572 69 0.490
dna recombination GO:0006310 32 0.480
Worm
mitotic dna integrity checkpoint GO:0044774 75 0.396
female meiosis chromosome segregation GO:0016321 33 0.391
mitotic g2 m transition checkpoint GO:0044818 70 0.369
mitotic g2 dna damage checkpoint GO:0007095 69 0.343
double strand break repair via homologous recombination GO:0000724 13 0.325
Worm
response to oxidative stress GO:0006979 86 0.311
meiotic chromosome segregation GO:0045132 59 0.311
programmed cell death GO:0012501 257 0.305
Worm
reciprocal meiotic recombination GO:0007131 19 0.291
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.265
meiotic cell cycle process GO:1903046 132 0.250
negative regulation of cell cycle phase transition GO:1901988 103 0.230
Worm
response to abiotic stimulus GO:0009628 341 0.225
telomere maintenance via recombination GO:0000722 1 0.224
negative regulation of mitotic cell cycle GO:0045930 109 0.219
postreplication repair GO:0006301 2 0.198
regulation of cell cycle phase transition GO:1901987 130 0.195
Worm
response to ionizing radiation GO:0010212 32 0.189
meiotic cell cycle GO:0051321 171 0.186
cell cycle checkpoint GO:0000075 95 0.172
Worm
alternative mrna splicing via spliceosome GO:0000380 60 0.162
chromosome segregation GO:0007059 157 0.154
death GO:0016265 284 0.150
Worm
dna conformation change GO:0071103 105 0.144
regulation of cell death GO:0010941 173 0.142
regulation of cell cycle process GO:0010564 181 0.132
Worm
chorion containing eggshell formation GO:0007304 105 0.120
dna geometric change GO:0032392 16 0.107
response to light stimulus GO:0009416 124 0.103
growth GO:0040007 359 0.102
Mouse
cellular response to ionizing radiation GO:0071479 15 0.102
signal transduction in response to dna damage GO:0042770 3 0.100
Worm
regulation of cysteine type endopeptidase activity GO:2000116 27 0.097
aromatic compound catabolic process GO:0019439 166 0.096
Worm
regulation of endopeptidase activity GO:0052548 36 0.095
phosphorylation GO:0016310 294 0.095
mitotic cell cycle checkpoint GO:0007093 88 0.095
response to alkaloid GO:0043279 26 0.093
nucleoside phosphate metabolic process GO:0006753 162 0.090
cell death GO:0008219 279 0.090
Worm
mitotic cell cycle phase transition GO:0044772 138 0.087
developmental growth GO:0048589 280 0.083
positive regulation of cellular component organization GO:0051130 156 0.083
organophosphate metabolic process GO:0019637 195 0.080
response to other organism GO:0051707 293 0.080
negative regulation of cell cycle process GO:0010948 109 0.080
Worm
heterocycle catabolic process GO:0046700 166 0.078
Worm
translesion synthesis GO:0019985 2 0.078
meiosis i GO:0007127 59 0.077
organic cyclic compound catabolic process GO:1901361 168 0.073
Worm
apoptotic process GO:0006915 159 0.072
Worm
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.070
Worm
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.068
positive regulation of molecular function GO:0044093 136 0.066
organelle fission GO:0048285 340 0.066
defense response GO:0006952 300 0.066
positive regulation of endopeptidase activity GO:0010950 26 0.065
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.065
response to alcohol GO:0097305 95 0.063
locomotory behavior GO:0007626 176 0.063
cellular response to gamma radiation GO:0071480 10 0.061
compound eye development GO:0048749 307 0.059
cell cycle phase transition GO:0044770 140 0.058
Worm
regulation of neuron death GO:1901214 26 0.057
nucleotide metabolic process GO:0009117 161 0.057
protein complex assembly GO:0006461 200 0.056
regulation of apoptotic process GO:0042981 130 0.056
purine nucleoside metabolic process GO:0042278 127 0.056
telomere maintenance GO:0000723 21 0.054
single organism catabolic process GO:0044712 228 0.052
dna replication GO:0006260 48 0.051
intracellular signal transduction GO:0035556 300 0.051
Worm
neuron apoptotic process GO:0051402 17 0.050
cell aging GO:0007569 2 0.049
nucleobase containing small molecule metabolic process GO:0055086 174 0.048
homeostatic process GO:0042592 199 0.048
positive regulation of biosynthetic process GO:0009891 316 0.047
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.047
positive regulation of cell death GO:0010942 69 0.047
regulation of programmed cell death GO:0043067 152 0.047
rna splicing GO:0008380 83 0.045
purine containing compound metabolic process GO:0072521 155 0.044
negative regulation of programmed cell death GO:0043069 72 0.044
ribose phosphate metabolic process GO:0019693 145 0.044
response to uv GO:0009411 24 0.043
purine nucleoside catabolic process GO:0006152 112 0.043
negative regulation of stem cell proliferation GO:2000647 30 0.043
chromosome organization GO:0051276 360 0.043
cell proliferation GO:0008283 299 0.043
macromolecular complex assembly GO:0065003 256 0.042
rna processing GO:0006396 147 0.042
response to camptothecin GO:1901563 2 0.042
glycosyl compound metabolic process GO:1901657 127 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.041
response to starvation GO:0042594 97 0.041
response to organic cyclic compound GO:0014070 89 0.041
nuclear division GO:0000280 332 0.040
positive regulation of programmed cell death GO:0043068 62 0.040
meiotic chromosome separation GO:0051307 8 0.040
appendage development GO:0048736 401 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
response to radiation GO:0009314 155 0.038
response to x ray GO:0010165 8 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
negative regulation of cell cycle GO:0045786 116 0.037
Worm
ribonucleoside metabolic process GO:0009119 127 0.037
response to ethanol GO:0045471 59 0.036
regulation of mitotic cell cycle phase transition GO:1901990 130 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
axon extension GO:0048675 32 0.035
purine ribonucleotide metabolic process GO:0009150 145 0.035
cellular catabolic process GO:0044248 372 0.034
Worm
meiotic nuclear division GO:0007126 151 0.034
atp metabolic process GO:0046034 49 0.034
dna biosynthetic process GO:0071897 24 0.034
regulation of catalytic activity GO:0050790 185 0.033
purine nucleoside monophosphate catabolic process GO:0009128 38 0.033
exocrine system development GO:0035272 162 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
Worm
purine nucleotide metabolic process GO:0006163 146 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
negative regulation of cell death GO:0060548 81 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
catabolic process GO:0009056 409 0.031
Worm
positive regulation of hydrolase activity GO:0051345 78 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.030
ribonucleotide metabolic process GO:0009259 145 0.030
negative regulation of neuron death GO:1901215 18 0.030
nucleoside triphosphate catabolic process GO:0009143 108 0.029
negative regulation of apoptotic process GO:0043066 63 0.029
small molecule metabolic process GO:0044281 305 0.029
reciprocal dna recombination GO:0035825 19 0.028
immune response GO:0006955 246 0.028
positive regulation of signaling GO:0023056 243 0.028
positive regulation of protein metabolic process GO:0051247 128 0.028
regulation of response to stress GO:0080134 200 0.028
intrinsic apoptotic signaling pathway GO:0097193 16 0.027
Worm
regulation of developmental growth GO:0048638 174 0.027
protein localization to chromatin GO:0071168 3 0.027
apoptotic signaling pathway GO:0097190 27 0.026
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
regulation of cell cycle GO:0051726 291 0.025
Worm
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
sensory perception GO:0007600 196 0.025
nucleosome organization GO:0034728 59 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
regulation of cell proliferation GO:0042127 163 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
regulation of intracellular signal transduction GO:1902531 236 0.024
positive regulation of gene expression GO:0010628 290 0.024
single organism biosynthetic process GO:0044711 206 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.023
resolution of meiotic recombination intermediates GO:0000712 6 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
protein dna complex subunit organization GO:0071824 86 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
cell motility GO:0048870 251 0.022
positive regulation of apoptotic signaling pathway GO:2001235 4 0.022
response to caffeine GO:0031000 12 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
male sex differentiation GO:0046661 25 0.022
regulation of cellular response to stress GO:0080135 89 0.022
regulation of dna metabolic process GO:0051052 34 0.021
regulation of double strand break repair GO:2000779 3 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
learning or memory GO:0007611 141 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
multi organism reproductive behavior GO:0044705 121 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
regulation of cell shape GO:0008360 113 0.020
germarium derived oocyte fate determination GO:0007294 26 0.020
protein phosphorylation GO:0006468 169 0.020
purine containing compound catabolic process GO:0072523 112 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
regulation of actin filament polymerization GO:0030833 25 0.020
developmental cell growth GO:0048588 52 0.020
cellular response to abiotic stimulus GO:0071214 58 0.020
mrna splicing via spliceosome GO:0000398 73 0.019
response to organonitrogen compound GO:0010243 75 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
germarium derived egg chamber formation GO:0007293 101 0.019
regulation of catabolic process GO:0009894 170 0.019
organic substance catabolic process GO:1901575 308 0.019
Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.019
Worm
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
regulation of immune system process GO:0002682 176 0.018
response to bacterium GO:0009617 198 0.018
response to endogenous stimulus GO:0009719 119 0.018
immune system process GO:0002376 347 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
regulation of protein metabolic process GO:0051246 256 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
negative regulation of neural precursor cell proliferation GO:2000178 27 0.018
regulation of dna recombination GO:0000018 4 0.018
endocytosis GO:0006897 310 0.017
chromosome separation GO:0051304 42 0.017
regulation of hydrolase activity GO:0051336 97 0.017
cell cycle g1 s phase transition GO:0044843 31 0.017
response to heat GO:0009408 63 0.017
single organism behavior GO:0044708 391 0.017
positive regulation of peptidase activity GO:0010952 29 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
zymogen activation GO:0031638 20 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
response to oxygen containing compound GO:1901700 200 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
regulation of cellular component size GO:0032535 98 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
actin filament based process GO:0030029 220 0.016
appendage morphogenesis GO:0035107 397 0.016
macromolecule catabolic process GO:0009057 161 0.016
Worm
ectopic germ cell programmed cell death GO:0035234 8 0.016
cell cycle arrest GO:0007050 4 0.016
histolysis GO:0007559 102 0.016
stress activated mapk cascade GO:0051403 52 0.015
polarity specification of dorsal ventral axis GO:0009951 6 0.015
protein complex biogenesis GO:0070271 201 0.015
ovarian follicle cell development GO:0030707 248 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
neuron projection extension GO:1990138 32 0.015
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.015
response to nitrogen compound GO:1901698 90 0.015
central nervous system development GO:0007417 201 0.015
regulation of peptidase activity GO:0052547 39 0.014
nucleoside catabolic process GO:0009164 112 0.014
cell type specific apoptotic process GO:0097285 38 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
molting cycle GO:0042303 56 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
developmental growth involved in morphogenesis GO:0060560 65 0.014
ion transport GO:0006811 145 0.014
chaeta development GO:0022416 97 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
mapk cascade GO:0000165 107 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
response to gamma radiation GO:0010332 17 0.014
cellular response to oxidative stress GO:0034599 28 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
metal ion transport GO:0030001 74 0.014
pigmentation GO:0043473 75 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
wound healing GO:0042060 75 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
oocyte fate determination GO:0030716 27 0.013
response to external biotic stimulus GO:0043207 293 0.013
organophosphate catabolic process GO:0046434 112 0.013
regulation of molecular function GO:0065009 217 0.013
positive regulation of cell proliferation GO:0008284 47 0.013
response to organic substance GO:0010033 284 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
telomere organization GO:0032200 21 0.013
nucleosome assembly GO:0006334 35 0.013
dna catabolic process GO:0006308 16 0.013
Worm
regulation of actin cytoskeleton organization GO:0032956 42 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
regulation of rna splicing GO:0043484 69 0.012
positive regulation of macroautophagy GO:0016239 8 0.012
response to copper ion GO:0046688 4 0.012
salivary gland development GO:0007431 162 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
female meiotic division GO:0007143 70 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
response to inorganic substance GO:0010035 44 0.012
positive regulation of organelle organization GO:0010638 65 0.012
cellular response to radiation GO:0071478 52 0.012
nucleotide catabolic process GO:0009166 109 0.012
cellular response to organic substance GO:0071310 132 0.012
circadian behavior GO:0048512 76 0.012
regulation of actin filament length GO:0030832 27 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
regulation of organelle organization GO:0033043 196 0.012
actin cytoskeleton organization GO:0030036 206 0.012
jnk cascade GO:0007254 50 0.011
positive regulation of signal transduction GO:0009967 223 0.011
aging GO:0007568 143 0.011
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
chromatin organization GO:0006325 207 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
Worm
response to biotic stimulus GO:0009607 294 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
regulation of proteolysis GO:0030162 87 0.011
regulation of phosphorylation GO:0042325 147 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
response to oxygen radical GO:0000305 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
karyosome formation GO:0030717 22 0.011
positive regulation of cell communication GO:0010647 250 0.011
cell growth GO:0016049 108 0.011
gtp metabolic process GO:0046039 72 0.011
chromatin modification GO:0016568 147 0.011
nucleoside metabolic process GO:0009116 127 0.011
response to temperature stimulus GO:0009266 106 0.010
organ growth GO:0035265 56 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
forebrain development GO:0030900 2 0.010
response to metal ion GO:0010038 23 0.010
regulation of growth GO:0040008 233 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
cellular protein modification process GO:0006464 438 0.010

mus201 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.044
organ system cancer DOID:0050686 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
cancer DOID:162 0 0.044
disease of anatomical entity DOID:7 0 0.043
breast cancer DOID:1612 0 0.020