|
|
axon development
|
GO:0061564 |
297 |
1.000
|
|
|
|
dendrite guidance
|
GO:0070983 |
21 |
1.000
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
58 |
1.000
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
1.000
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
1.000
|
|
|
|
photoreceptor cell axon guidance
|
GO:0072499 |
23 |
1.000
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
1.000
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
28 |
0.999
|
Rat |
|
|
axon midline choice point recognition
|
GO:0016199 |
26 |
0.999
|
|
|
|
positive regulation of axonogenesis
|
GO:0050772 |
2 |
0.999
|
Human |
|
|
dorsal ventral axon guidance
|
GO:0033563 |
2 |
0.998
|
Worm |
|
|
cell recognition
|
GO:0008037 |
102 |
0.997
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
4 |
0.997
|
Zebrafish |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
12 |
0.997
|
Zebrafish Mouse |
|
|
dendrite development
|
GO:0016358 |
204 |
0.996
|
|
|
|
chemotaxis
|
GO:0006935 |
249 |
0.996
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
12 |
0.995
|
Human Zebrafish |
|
|
ventral cord development
|
GO:0007419 |
16 |
0.995
|
Fly |
|
|
axon choice point recognition
|
GO:0016198 |
26 |
0.995
|
|
|
|
synapse organization
|
GO:0050808 |
196 |
0.994
|
Zebrafish |
|
|
taxis
|
GO:0042330 |
304 |
0.993
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
10 |
0.992
|
Zebrafish |
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
6 |
0.992
|
Zebrafish |
|
|
dendrite morphogenesis
|
GO:0048813 |
199 |
0.991
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.989
|
Zebrafish |
|
|
formation of anatomical boundary
|
GO:0048859 |
37 |
0.989
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.988
|
|
|
|
olfactory bulb axon guidance
|
GO:0071678 |
3 |
0.982
|
|
|
|
central nervous system development
|
GO:0007417 |
201 |
0.976
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
69 |
0.975
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.969
|
|
|
|
brain development
|
GO:0007420 |
120 |
0.968
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.960
|
Human Zebrafish |
|
|
cell cell adhesion
|
GO:0098609 |
26 |
0.959
|
Human |
|
|
neuron recognition
|
GO:0008038 |
101 |
0.945
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.942
|
|
|
|
heart development
|
GO:0007507 |
82 |
0.941
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.940
|
Zebrafish |
|
|
glial cell migration
|
GO:0008347 |
31 |
0.940
|
|
|
|
lamellipodium organization
|
GO:0097581 |
21 |
0.938
|
Zebrafish |
|
|
growth
|
GO:0040007 |
359 |
0.934
|
Zebrafish Mouse |
|
|
formation of organ boundary
|
GO:0010160 |
30 |
0.932
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.926
|
|
|
|
roundabout signaling pathway
|
GO:0035385 |
4 |
0.925
|
|
|
|
regulation of photoreceptor cell axon guidance
|
GO:2000289 |
5 |
0.923
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
3 |
0.919
|
Zebrafish |
|
|
axon extension involved in axon guidance
|
GO:0048846 |
10 |
0.917
|
Zebrafish |
|
|
respiratory system development
|
GO:0060541 |
213 |
0.916
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
65 |
0.913
|
Zebrafish Mouse |
|
|
positive regulation of axon extension
|
GO:0045773 |
2 |
0.907
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
10 |
0.902
|
|
|
|
forebrain development
|
GO:0030900 |
2 |
0.900
|
Human Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
69 |
0.895
|
Human |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.889
|
Human |
|
|
tube development
|
GO:0035295 |
244 |
0.879
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
61 |
0.878
|
Human Zebrafish Rat |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.873
|
|
|
|
muscle organ development
|
GO:0007517 |
127 |
0.858
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
29 |
0.847
|
Human |
|
|
axon extension
|
GO:0048675 |
32 |
0.843
|
Zebrafish |
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.835
|
Zebrafish |
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.835
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.827
|
|
|
|
salivary gland boundary specification
|
GO:0007432 |
8 |
0.820
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
4 |
0.819
|
|
|
|
positive regulation of axon guidance
|
GO:1902669 |
1 |
0.817
|
|
|
|
branching involved in open tracheal system development
|
GO:0060446 |
45 |
0.816
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.813
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.811
|
|
|
|
convergent extension
|
GO:0060026 |
2 |
0.805
|
Zebrafish |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
89 |
0.796
|
|
|
|
negative regulation of growth
|
GO:0045926 |
84 |
0.790
|
Zebrafish |
|
|
synapse assembly
|
GO:0007416 |
143 |
0.789
|
Zebrafish |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
12 |
0.785
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
8 |
0.780
|
Human Zebrafish Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
22 |
0.756
|
|
|
|
spinal cord development
|
GO:0021510 |
1 |
0.753
|
Rat |
|
|
neuron projection extension involved in neuron projection guidance
|
GO:1902284 |
10 |
0.752
|
Zebrafish |
|
|
cell motility
|
GO:0048870 |
251 |
0.747
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
32 |
0.731
|
Human Zebrafish |
|
|
kidney development
|
GO:0001822 |
3 |
0.727
|
Human Mouse |
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.725
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
92 |
0.725
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
27 |
0.721
|
|
|
|
head development
|
GO:0060322 |
135 |
0.717
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.713
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.712
|
|
|
|
neuron projection extension
|
GO:1990138 |
32 |
0.711
|
Zebrafish |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.711
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
163 |
0.707
|
Human Zebrafish Rat |
|
|
regulation of dendrite development
|
GO:0050773 |
37 |
0.705
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
3 |
0.703
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.699
|
|
|
|
open tracheal system development
|
GO:0007424 |
204 |
0.698
|
|
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.689
|
Human Mouse |
|
|
neuron migration
|
GO:0001764 |
5 |
0.679
|
Mouse Worm Fly |
|
|
neuroblast development
|
GO:0014019 |
13 |
0.679
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
29 |
0.673
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
12 |
0.661
|
Human |
|
|
regionalization
|
GO:0003002 |
416 |
0.659
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.658
|
Zebrafish |
|
|
developmental growth
|
GO:0048589 |
280 |
0.643
|
Zebrafish Mouse |
|
|
compound eye photoreceptor cell differentiation
|
GO:0001751 |
140 |
0.643
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
41 |
0.631
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.625
|
Human |
|
|
eye development
|
GO:0001654 |
323 |
0.620
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
17 |
0.616
|
Fly |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
8 |
0.607
|
Human Zebrafish Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.604
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.597
|
Zebrafish Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
92 |
0.587
|
Zebrafish |
|
|
regulation of circadian rhythm
|
GO:0042752 |
49 |
0.584
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.578
|
Human Zebrafish Rat |
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.576
|
|
|
|
telencephalon development
|
GO:0021537 |
2 |
0.572
|
Human Mouse |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.566
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.559
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.556
|
|
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.548
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.542
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
62 |
0.535
|
Zebrafish |
|
|
cardioblast cell fate specification
|
GO:0042685 |
9 |
0.532
|
Fly |
|
|
localization of cell
|
GO:0051674 |
257 |
0.525
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.523
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.522
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.520
|
Zebrafish |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
25 |
0.512
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.503
|
|
|
|
developmental cell growth
|
GO:0048588 |
52 |
0.501
|
Zebrafish |
|
|
organ formation
|
GO:0048645 |
39 |
0.500
|
|
|
|
sex differentiation
|
GO:0007548 |
81 |
0.500
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.499
|
|
|
|
reproductive structure development
|
GO:0048608 |
74 |
0.497
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
50 |
0.481
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
45 |
0.473
|
|
|
|
regulation of growth
|
GO:0040008 |
233 |
0.472
|
Zebrafish |
|
|
regulation of peptidase activity
|
GO:0052547 |
39 |
0.472
|
Human |
|
|
digestive system development
|
GO:0055123 |
149 |
0.470
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.469
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
123 |
0.466
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
17 |
0.465
|
Human |
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.465
|
Zebrafish |
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.462
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.461
|
Human Zebrafish |
|
|
central complex development
|
GO:0048036 |
9 |
0.458
|
Fly |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.457
|
|
|
|
axonal fasciculation
|
GO:0007413 |
12 |
0.455
|
Zebrafish |
|
|
regulation of cell size
|
GO:0008361 |
63 |
0.445
|
Zebrafish |
|
|
circadian rhythm
|
GO:0007623 |
105 |
0.441
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.441
|
Zebrafish |
|
|
reproductive behavior
|
GO:0019098 |
122 |
0.436
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
98 |
0.436
|
Zebrafish |
|
|
renal system development
|
GO:0072001 |
72 |
0.429
|
Human Mouse |
|
|
mesoderm development
|
GO:0007498 |
78 |
0.426
|
|
|
|
heart morphogenesis
|
GO:0003007 |
32 |
0.422
|
|
|
|
synaptic target recognition
|
GO:0008039 |
45 |
0.416
|
Fly |
|
|
stem cell development
|
GO:0048864 |
79 |
0.412
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
26 |
0.411
|
Human |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.405
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
110 |
0.398
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
3 |
0.396
|
Zebrafish |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.392
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
59 |
0.391
|
|
|
|
mating behavior
|
GO:0007617 |
106 |
0.381
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.377
|
|
|
|
negative regulation of chemotaxis
|
GO:0050922 |
1 |
0.376
|
Human Zebrafish |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
31 |
0.376
|
|
|
|
regulation of lamellipodium organization
|
GO:1902743 |
15 |
0.372
|
|
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.372
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
21 |
0.372
|
Zebrafish |
|
|
exocrine system development
|
GO:0035272 |
162 |
0.370
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.369
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.361
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
93 |
0.352
|
Zebrafish |
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
15 |
0.350
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.345
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
9 |
0.343
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
7 |
0.339
|
Zebrafish |
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
9 |
0.336
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.336
|
|
|
|
nucleus localization
|
GO:0051647 |
34 |
0.335
|
|
|
|
gonad development
|
GO:0008406 |
50 |
0.330
|
|
|
|
actin filament polymerization
|
GO:0030041 |
27 |
0.329
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
2 |
0.327
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.325
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.322
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
14 |
0.322
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.322
|
Human |
|
|
phosphorylation
|
GO:0016310 |
294 |
0.318
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.313
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
21 |
0.310
|
|
|
|
gliogenesis
|
GO:0042063 |
80 |
0.309
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.303
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
39 |
0.302
|
Zebrafish |
|
|
positive regulation of cell development
|
GO:0010720 |
61 |
0.301
|
Human |
|
|
muscle structure development
|
GO:0061061 |
224 |
0.296
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.295
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.292
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.291
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.289
|
Human |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
45 |
0.288
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.284
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
121 |
0.282
|
|
|
|
cardiovascular system development
|
GO:0072358 |
82 |
0.282
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.280
|
Human |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.277
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.276
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.270
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.270
|
Zebrafish |
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.269
|
Zebrafish |
|
|
cell proliferation
|
GO:0008283 |
299 |
0.266
|
Human Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
27 |
0.264
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.262
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.261
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.257
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.254
|
Human |
|
|
mapk cascade
|
GO:0000165 |
107 |
0.253
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
26 |
0.253
|
Human |
|
|
epithelial cell migration open tracheal system
|
GO:0007427 |
32 |
0.250
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
29 |
0.248
|
Fly |
|
|
homeostatic process
|
GO:0042592 |
199 |
0.246
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
62 |
0.245
|
Human |
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.245
|
|
|
|
response to wounding
|
GO:0009611 |
94 |
0.243
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.243
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
47 |
0.240
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
110 |
0.238
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.235
|
|
|
|
gastrulation
|
GO:0007369 |
70 |
0.234
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
53 |
0.230
|
Zebrafish |
|
|
regulation of epithelial cell migration open tracheal system
|
GO:2000274 |
11 |
0.229
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
36 |
0.226
|
Human |
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
9 |
0.222
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
2 |
0.218
|
Zebrafish |
|
|
cell fate specification
|
GO:0001708 |
71 |
0.218
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
27 |
0.216
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
10 |
0.216
|
Zebrafish |
|
|
camera type eye development
|
GO:0043010 |
4 |
0.215
|
|
|
|
reproductive system development
|
GO:0061458 |
74 |
0.214
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.213
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.203
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
42 |
0.203
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.202
|
Human |
|
|
cell growth
|
GO:0016049 |
108 |
0.201
|
Zebrafish |
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.199
|
|
|
|
dendrite self avoidance
|
GO:0070593 |
8 |
0.195
|
|
|
|
male gamete generation
|
GO:0048232 |
201 |
0.194
|
|
|
|
stem cell fate commitment
|
GO:0048865 |
25 |
0.194
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
88 |
0.192
|
Zebrafish |
|
|
mating
|
GO:0007618 |
120 |
0.191
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
16 |
0.190
|
Zebrafish |
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.188
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.188
|
|
|
|
hemopoiesis
|
GO:0030097 |
46 |
0.188
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.185
|
Human |
|
|
bmp signaling pathway
|
GO:0030509 |
27 |
0.184
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
22 |
0.182
|
Human Zebrafish |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.178
|
Zebrafish |
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
116 |
0.177
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.177
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.176
|
|
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.175
|
|
|
|
digestive tract development
|
GO:0048565 |
149 |
0.174
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.173
|
|
|
|
axonal defasciculation
|
GO:0007414 |
12 |
0.171
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
3 |
0.167
|
Zebrafish |
|
|
regulation of behavior
|
GO:0050795 |
75 |
0.166
|
Human Zebrafish |
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.165
|
Human Zebrafish |
|
|
embryonic heart tube development
|
GO:0035050 |
22 |
0.165
|
|
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.163
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.159
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.159
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
13 |
0.159
|
Zebrafish |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.157
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.157
|
Human Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.151
|
Zebrafish |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.150
|
Human Mouse |
|
|
eye photoreceptor cell fate commitment
|
GO:0042706 |
37 |
0.146
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
29 |
0.146
|
Human |
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.145
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.144
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
35 |
0.144
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
52 |
0.144
|
Human |
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.141
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.140
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.137
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
92 |
0.136
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
115 |
0.133
|
Human Zebrafish |
|
|
actin filament based process
|
GO:0030029 |
220 |
0.133
|
|
|
|
protein polymerization
|
GO:0051258 |
42 |
0.132
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.129
|
|
|
|
compound eye development
|
GO:0048749 |
307 |
0.128
|
|
|
|
cell fate determination
|
GO:0001709 |
91 |
0.127
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
4 |
0.127
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
10 |
0.124
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.123
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.122
|
Zebrafish |
|
|
tissue migration
|
GO:0090130 |
155 |
0.121
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
69 |
0.121
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.120
|
|
|
|
male courtship behavior veined wing extension
|
GO:0048065 |
22 |
0.114
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.113
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.112
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.112
|
Human |
|
|
cardioblast cell fate commitment
|
GO:0042684 |
14 |
0.109
|
Fly |
|
|
neuron maturation
|
GO:0042551 |
31 |
0.107
|
|
|
|
urogenital system development
|
GO:0001655 |
72 |
0.106
|
Human Mouse |
|
|
gland morphogenesis
|
GO:0022612 |
145 |
0.106
|
Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
26 |
0.105
|
Human |
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.105
|
Zebrafish |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
16 |
0.104
|
Human |
|
|
epithelium migration
|
GO:0090132 |
148 |
0.103
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
103 |
0.102
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.100
|
|
|
|
negative regulation of behavior
|
GO:0048521 |
8 |
0.099
|
Human Zebrafish |
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.097
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.097
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
18 |
0.096
|
|
|
|
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance
|
GO:2000305 |
2 |
0.096
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
8 |
0.096
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.095
|
|
|
|
cardioblast differentiation
|
GO:0010002 |
20 |
0.094
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.092
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.092
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.092
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.091
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
13 |
0.091
|
|
|
|
regulation of locomotion
|
GO:0040012 |
42 |
0.090
|
|
|
|
neuron remodeling
|
GO:0016322 |
29 |
0.090
|
|
|
|
branch fusion open tracheal system
|
GO:0035147 |
17 |
0.090
|
|
|
|
positive chemotaxis
|
GO:0050918 |
4 |
0.089
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.089
|
|
|
|
actin filament organization
|
GO:0007015 |
126 |
0.088
|
|
|
|
response to growth factor
|
GO:0070848 |
31 |
0.088
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.087
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.087
|
Zebrafish Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
27 |
0.087
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.086
|
|
|
|
cell projection assembly
|
GO:0030031 |
94 |
0.085
|
Zebrafish |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
45 |
0.084
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.084
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.084
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.083
|
|
|
|
neuron fate commitment
|
GO:0048663 |
50 |
0.083
|
|
|
|
immune system development
|
GO:0002520 |
57 |
0.083
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.080
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
88 |
0.080
|
Zebrafish |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
3 |
0.077
|
Zebrafish |
|
|
negative regulation of organelle organization
|
GO:0010639 |
56 |
0.077
|
|
|
|
mushroom body development
|
GO:0016319 |
70 |
0.076
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.076
|
|
|
|
specification of symmetry
|
GO:0009799 |
13 |
0.075
|
Zebrafish |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.074
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.073
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.073
|
Human |
|
|
spermatid differentiation
|
GO:0048515 |
114 |
0.071
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.071
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.071
|
|
|
|
filopodium assembly
|
GO:0046847 |
33 |
0.069
|
Zebrafish |
|
|
cytoplasmic transport
|
GO:0016482 |
130 |
0.069
|
|
|
|
anterior commissure morphogenesis
|
GO:0021960 |
2 |
0.069
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
19 |
0.068
|
|
|
|
limb morphogenesis
|
GO:0035108 |
1 |
0.067
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.067
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
1 |
0.067
|
Zebrafish |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.067
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.066
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
25 |
0.066
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
27 |
0.065
|
Human |
|
|
death
|
GO:0016265 |
284 |
0.065
|
Human |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.065
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.065
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.064
|
Human |
|
|
protein modification process
|
GO:0036211 |
438 |
0.064
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.064
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.064
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
28 |
0.064
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.063
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.063
|
Mouse |
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.063
|
Zebrafish |
|
|
cranial nerve development
|
GO:0021545 |
1 |
0.062
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
3 |
0.062
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.061
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.060
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
98 |
0.060
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.060
|
Human |
|
|
regulation of transport
|
GO:0051049 |
181 |
0.058
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.058
|
|
|
|
larval development
|
GO:0002164 |
104 |
0.058
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
30 |
0.057
|
|
|
|
spermatid development
|
GO:0007286 |
98 |
0.057
|
|
|
|
neural retina development
|
GO:0003407 |
4 |
0.056
|
|
|
|
myotube differentiation
|
GO:0014902 |
46 |
0.056
|
|
|
|
hindbrain development
|
GO:0030902 |
2 |
0.055
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.055
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
43 |
0.055
|
Zebrafish |
|
|
muscle tissue development
|
GO:0060537 |
30 |
0.054
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
64 |
0.054
|
Zebrafish |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
30 |
0.054
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.053
|
|
|
|
determination of muscle attachment site
|
GO:0016204 |
7 |
0.052
|
|
|
|
neuroblast fate commitment
|
GO:0014017 |
19 |
0.052
|
|
|
|
chaeta development
|
GO:0022416 |
97 |
0.051
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
14 |
0.051
|
|
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.050
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
3 |
0.050
|
|
|
|
organelle localization
|
GO:0051640 |
148 |
0.049
|
|
|
|
regulation of r7 cell differentiation
|
GO:0045676 |
15 |
0.049
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
11 |
0.048
|
|
|
|
cognition
|
GO:0050890 |
141 |
0.048
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.048
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.048
|
|
|
|
male courtship behavior
|
GO:0008049 |
63 |
0.047
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.046
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
1 |
0.045
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.045
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
37 |
0.044
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
22 |
0.044
|
|
|
|
entrainment of circadian clock
|
GO:0009649 |
16 |
0.044
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.044
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
68 |
0.043
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
223 |
0.043
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.043
|
Zebrafish |
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.042
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
109 |
0.041
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
195 |
0.040
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.040
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
8 |
0.040
|
Zebrafish |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.039
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
23 |
0.039
|
Human |
|
|
wound healing
|
GO:0042060 |
75 |
0.038
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.038
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
13 |
0.038
|
Zebrafish |
|
|
formation of primary germ layer
|
GO:0001704 |
24 |
0.038
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
52 |
0.038
|
|
|
|
positive regulation of receptor mediated endocytosis
|
GO:0048260 |
7 |
0.037
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
8 |
0.037
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
51 |
0.037
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.037
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
45 |
0.036
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.036
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.036
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
109 |
0.036
|
|
|
|
chaeta morphogenesis
|
GO:0008407 |
42 |
0.035
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
7 |
0.035
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
71 |
0.035
|
|
|
|
response to nutrient levels
|
GO:0031667 |
114 |
0.035
|
|
|
|
regulation of cell growth
|
GO:0001558 |
43 |
0.033
|
Zebrafish |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
93 |
0.033
|
|
|
|
leg disc development
|
GO:0035218 |
92 |
0.033
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
44 |
0.032
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
29 |
0.032
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
127 |
0.032
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.031
|
|
|
|
somatic muscle development
|
GO:0007525 |
66 |
0.031
|
|
|
|
photoreceptor cell fate commitment
|
GO:0046552 |
41 |
0.031
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.031
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.031
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.031
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.031
|
|
|
|
circulatory system process
|
GO:0003013 |
37 |
0.030
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.030
|
|
|
|
blood circulation
|
GO:0008015 |
26 |
0.030
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.030
|
Human |
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.030
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.029
|
Human Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.029
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
50 |
0.029
|
|
|
|
protein transport
|
GO:0015031 |
155 |
0.029
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
9 |
0.029
|
|
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
24 |
0.029
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
26 |
0.028
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
17 |
0.028
|
|
|
|
nephron epithelium development
|
GO:0072009 |
3 |
0.028
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
155 |
0.028
|
|
|
|
collateral sprouting
|
GO:0048668 |
3 |
0.027
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.027
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
174 |
0.026
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
78 |
0.026
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.026
|
|
|
|
ectoderm development
|
GO:0007398 |
6 |
0.026
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
145 |
0.026
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
162 |
0.026
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
48 |
0.026
|
|
|
|
glial cell differentiation
|
GO:0010001 |
35 |
0.026
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
136 |
0.026
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.026
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.025
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.025
|
|
|
|
response to light stimulus
|
GO:0009416 |
124 |
0.025
|
|
|
|
axon regeneration
|
GO:0031103 |
8 |
0.025
|
|
