Drosophila melanogaster

125 known processes

Taf2 (Dmel_CG6711)

TBP-associated factor 2

(Aliases: dTAF150,Dmel\CG6711,TAF2,TAF[[II]],Taf150,dTAF[[II]]150,TAF150,dTAF II 150,TAF,TAFII150,TFIID,TafII150,Taf[[II]]150,TAF[[II]]150,TAF[II]150,dTAFII150,CG6711)

Taf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone mrna metabolic process GO:0008334 8 0.334
dendrite development GO:0016358 204 0.250
protein modification process GO:0036211 438 0.209
dendrite morphogenesis GO:0048813 199 0.183
transcription from rna polymerase ii promoter GO:0006366 368 0.152
spindle organization GO:0007051 253 0.147
positive regulation of rna biosynthetic process GO:1902680 266 0.144
rna processing GO:0006396 147 0.136
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.121
imaginal disc derived appendage development GO:0048737 399 0.120
sister chromatid segregation GO:0000819 92 0.113
regulation of cell cycle process GO:0010564 181 0.110
mrna metabolic process GO:0016071 124 0.098
axon development GO:0061564 297 0.093
regulation of mitotic cell cycle GO:0007346 190 0.092
mitotic sister chromatid segregation GO:0000070 87 0.090
growth GO:0040007 359 0.084
imaginal disc derived appendage morphogenesis GO:0035114 395 0.083
vesicle mediated transport GO:0016192 381 0.083
protein modification by small protein conjugation or removal GO:0070647 106 0.079
endocytosis GO:0006897 310 0.078
eye development GO:0001654 323 0.074
positive regulation of response to stimulus GO:0048584 323 0.073
axonogenesis GO:0007409 290 0.072
mitotic spindle organization GO:0007052 220 0.072
ubiquitin dependent protein catabolic process GO:0006511 78 0.071
inter male aggressive behavior GO:0002121 60 0.071
mitotic nuclear division GO:0007067 213 0.064
positive regulation of transcription dna templated GO:0045893 266 0.062
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.061
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.061
chromosome segregation GO:0007059 157 0.060
positive regulation of gene expression GO:0010628 290 0.059
cell death GO:0008219 279 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.053
phagocytosis GO:0006909 215 0.051
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.051
cellular protein modification process GO:0006464 438 0.050
post embryonic appendage morphogenesis GO:0035120 385 0.050
positive regulation of signal transduction GO:0009967 223 0.049
positive regulation of rna metabolic process GO:0051254 271 0.049
chromatin assembly or disassembly GO:0006333 52 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.048
catabolic process GO:0009056 409 0.047
mrna polyadenylation GO:0006378 11 0.047
mitotic cell cycle phase transition GO:0044772 138 0.047
Human
negative regulation of cell cycle process GO:0010948 109 0.045
organelle assembly GO:0070925 198 0.044
cellular macromolecular complex assembly GO:0034622 153 0.043
wing disc morphogenesis GO:0007472 344 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
eye photoreceptor cell differentiation GO:0001754 145 0.042
neuron projection guidance GO:0097485 241 0.041
regulation of cell cycle GO:0051726 291 0.041
peptidyl amino acid modification GO:0018193 105 0.040
protein complex assembly GO:0006461 200 0.039
g2 dna damage checkpoint GO:0031572 69 0.039
cell cycle checkpoint GO:0000075 95 0.039
rna polyadenylation GO:0043631 12 0.039
multi organism behavior GO:0051705 175 0.038
spermatid differentiation GO:0048515 114 0.036
proteolysis GO:0006508 192 0.036
mitotic sister chromatid separation GO:0051306 30 0.036
modification dependent macromolecule catabolic process GO:0043632 79 0.036
proteasomal protein catabolic process GO:0010498 59 0.035
positive regulation of signaling GO:0023056 243 0.035
appendage morphogenesis GO:0035107 397 0.035
cellular response to dna damage stimulus GO:0006974 223 0.034
body morphogenesis GO:0010171 2 0.034
axon guidance GO:0007411 233 0.034
photoreceptor cell differentiation GO:0046530 170 0.034
macromolecular complex assembly GO:0065003 256 0.033
apoptotic process GO:0006915 159 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.033
spermatogenesis GO:0007283 200 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
regulation of rna splicing GO:0043484 69 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
non sensory hair organization GO:0035316 47 0.031
eye morphogenesis GO:0048592 260 0.031
regulation of cell cycle phase transition GO:1901987 130 0.031
positive regulation of intracellular signal transduction GO:1902533 116 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
negative regulation of neuroblast proliferation GO:0007406 27 0.030
regulation of proteasomal protein catabolic process GO:0061136 39 0.030
dna integrity checkpoint GO:0031570 81 0.030
mitotic cell cycle checkpoint GO:0007093 88 0.030
imaginal disc derived leg morphogenesis GO:0007480 80 0.030
aggressive behavior GO:0002118 63 0.029
programmed cell death GO:0012501 257 0.029
compound eye photoreceptor cell differentiation GO:0001751 140 0.029
hair cell differentiation GO:0035315 47 0.028
appendage development GO:0048736 401 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
cell proliferation GO:0008283 299 0.028
macromolecule catabolic process GO:0009057 161 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
establishment of rna localization GO:0051236 47 0.026
nitrogen compound transport GO:0071705 85 0.026
cell division GO:0051301 248 0.025
organic substance transport GO:0071702 257 0.025
rna localization GO:0006403 115 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
dna metabolic process GO:0006259 227 0.024
rna transport GO:0050658 46 0.024
protein dna complex subunit organization GO:0071824 86 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
regulation of protein catabolic process GO:0042176 55 0.023
gland development GO:0048732 191 0.023
internal protein amino acid acetylation GO:0006475 38 0.023
regulation of gene silencing GO:0060968 63 0.023
amine metabolic process GO:0009308 12 0.022
regulation of erk1 and erk2 cascade GO:0070372 39 0.022
chromatin silencing GO:0006342 76 0.022
response to oxidative stress GO:0006979 86 0.022
cellular catabolic process GO:0044248 372 0.022
negative regulation of gene expression GO:0010629 387 0.022
peptidyl lysine acetylation GO:0018394 39 0.022
mrna processing GO:0006397 104 0.021
chromosome organization GO:0051276 360 0.021
cell cycle phase transition GO:0044770 140 0.021
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.021
gonad development GO:0008406 50 0.021
organic substance catabolic process GO:1901575 308 0.021
protein modification by small protein conjugation GO:0032446 79 0.020
regulation of neuron differentiation GO:0045664 103 0.020
alternative mrna splicing via spliceosome GO:0000380 60 0.020
gene silencing GO:0016458 138 0.020
chromatin modification GO:0016568 147 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
neuron fate commitment GO:0048663 50 0.020
cellular protein catabolic process GO:0044257 83 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
regulation of neuroblast proliferation GO:1902692 34 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
single organism biosynthetic process GO:0044711 206 0.018
centriole replication GO:0007099 24 0.018
chemotaxis GO:0006935 249 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
chromosome separation GO:0051304 42 0.017
regulation of chromosome organization GO:0033044 64 0.017
regionalization GO:0003002 416 0.017
nuclear division GO:0000280 332 0.017
jak stat cascade GO:0007259 49 0.017
open tracheal system development GO:0007424 204 0.017
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.017
regulation of proteolysis GO:0030162 87 0.017
compound eye development GO:0048749 307 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.016
regulation of molecular function GO:0065009 217 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
regulation of neuron projection development GO:0010975 69 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
cellular response to oxidative stress GO:0034599 28 0.015
imaginal disc derived wing vein specification GO:0007474 48 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
regulation of mitotic sister chromatid separation GO:0010965 28 0.015
negative regulation of cell cycle GO:0045786 116 0.015
histone acetylation GO:0016573 38 0.015
regulation of erbb signaling pathway GO:1901184 42 0.015
ribosomal large subunit biogenesis GO:0042273 1 0.014
chromatin organization GO:0006325 207 0.014
imaginal disc derived wing hair organization GO:0035317 45 0.014
developmental growth GO:0048589 280 0.014
negative regulation of protein catabolic process GO:0042177 17 0.014
ncrna metabolic process GO:0034660 43 0.014
regulation of organelle organization GO:0033043 196 0.014
mrna splice site selection GO:0006376 1 0.014
positive regulation of cell communication GO:0010647 250 0.014
regulation of chromosome segregation GO:0051983 32 0.013
sex differentiation GO:0007548 81 0.013
embryonic hindgut morphogenesis GO:0048619 48 0.013
regulation of intracellular transport GO:0032386 64 0.013
establishment of spindle localization GO:0051293 22 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
meiotic cell cycle process GO:1903046 132 0.013
histone h3 acetylation GO:0043966 11 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
actin cytoskeleton organization GO:0030036 206 0.013
regulation of microtubule based process GO:0032886 49 0.013
exocrine system development GO:0035272 162 0.013
nucleobase containing compound transport GO:0015931 56 0.013
response to heat GO:0009408 63 0.013
regulation of neurogenesis GO:0050767 158 0.013
regulation of mrna metabolic process GO:1903311 72 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
photoreceptor cell development GO:0042461 96 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
protein acetylation GO:0006473 39 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
negative regulation of organelle organization GO:0010639 56 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
histone h4 acetylation GO:0043967 13 0.012
regulation of catabolic process GO:0009894 170 0.012
protein complex biogenesis GO:0070271 201 0.012
establishment of localization in cell GO:0051649 402 0.012
response to light stimulus GO:0009416 124 0.012
dorsal ventral pattern formation GO:0009953 133 0.011
imaginal disc pattern formation GO:0007447 91 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
response to abiotic stimulus GO:0009628 341 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
organelle fission GO:0048285 340 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
mrna 3 end processing GO:0031124 28 0.011
intracellular transport GO:0046907 228 0.011
male gamete generation GO:0048232 201 0.011
histone lysine demethylation GO:0070076 6 0.011
centrosome cycle GO:0007098 137 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
outflow tract morphogenesis GO:0003151 4 0.011
spindle assembly involved in mitosis GO:0090307 50 0.011
peptidyl lysine modification GO:0018205 57 0.011
localization of cell GO:0051674 257 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
nucleic acid transport GO:0050657 46 0.011
aromatic compound catabolic process GO:0019439 166 0.011
protein localization GO:0008104 284 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.010
histone mrna 3 end processing GO:0006398 8 0.010
death GO:0016265 284 0.010
regulation of growth GO:0040008 233 0.010
taxis GO:0042330 304 0.010
multi multicellular organism process GO:0044706 123 0.010
protein dna complex assembly GO:0065004 63 0.010
single organism intracellular transport GO:1902582 207 0.010
reproductive structure development GO:0048608 74 0.010
atp dependent chromatin remodeling GO:0043044 22 0.010

Taf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 0 0.015
central nervous system disease DOID:331 0 0.015
disease of anatomical entity DOID:7 0 0.015
neurodegenerative disease DOID:1289 0 0.015
nervous system disease DOID:863 0 0.015