Drosophila melanogaster

2 known processes

Pbgs (Dmel_CG10335)

Porphobilinogen synthase

(Aliases: Dmel\CG10335,CG10335,DmPBGS)

Pbgs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 65 0.075
response to abiotic stimulus GO:0009628 341 0.074
cytoplasmic transport GO:0016482 130 0.070
sulfur compound metabolic process GO:0006790 59 0.067
oxoacid metabolic process GO:0043436 103 0.054
small molecule metabolic process GO:0044281 305 0.053
single organism cellular localization GO:1902580 180 0.051
organic substance transport GO:0071702 257 0.048
intracellular transport GO:0046907 228 0.045
protein modification process GO:0036211 438 0.040
establishment of localization in cell GO:0051649 402 0.040
protein transport GO:0015031 155 0.038
mitochondrial transport GO:0006839 8 0.038
cellular macromolecule localization GO:0070727 220 0.037
organic acid metabolic process GO:0006082 103 0.036
cellular protein modification process GO:0006464 438 0.034
intracellular protein transport GO:0006886 104 0.034
organonitrogen compound metabolic process GO:1901564 318 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
establishment of protein localization GO:0045184 163 0.031
protein localization GO:0008104 284 0.028
carboxylic acid metabolic process GO:0019752 92 0.027
cellular protein localization GO:0034613 160 0.027
body morphogenesis GO:0010171 2 0.026
ion transport GO:0006811 145 0.025
protein targeting GO:0006605 64 0.024
positive regulation of signaling GO:0023056 243 0.024
cellular modified amino acid metabolic process GO:0006575 45 0.024
response to oxygen containing compound GO:1901700 200 0.024
protein localization to organelle GO:0033365 82 0.022
regulation of molecular function GO:0065009 217 0.021
response to organic substance GO:0010033 284 0.021
spindle organization GO:0007051 253 0.021
macromolecular complex assembly GO:0065003 256 0.020
cellular amide metabolic process GO:0043603 80 0.020
regulation of cell cycle GO:0051726 291 0.019
regulation of catalytic activity GO:0050790 185 0.019
carbohydrate metabolic process GO:0005975 82 0.019
endocytosis GO:0006897 310 0.019
organic substance catabolic process GO:1901575 308 0.019
positive regulation of cell communication GO:0010647 250 0.018
response to other organism GO:0051707 293 0.018
positive regulation of signal transduction GO:0009967 223 0.018
pigment metabolic process GO:0042440 84 0.017
response to temperature stimulus GO:0009266 106 0.017
vesicle mediated transport GO:0016192 381 0.017
cellular catabolic process GO:0044248 372 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
catabolic process GO:0009056 409 0.016
homeostatic process GO:0042592 199 0.016
phosphorylation GO:0016310 294 0.016
central nervous system development GO:0007417 201 0.016
acyl coa metabolic process GO:0006637 3 0.016
regulation of localization GO:0032879 275 0.016
regulation of transport GO:0051049 181 0.016
regionalization GO:0003002 416 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
response to heat GO:0009408 63 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
axon development GO:0061564 297 0.015
oocyte differentiation GO:0009994 145 0.015
taxis GO:0042330 304 0.015
single organism catabolic process GO:0044712 228 0.015
response to nutrient levels GO:0031667 114 0.015
response to extracellular stimulus GO:0009991 116 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
lateral inhibition GO:0046331 206 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
protein complex biogenesis GO:0070271 201 0.015
peptide metabolic process GO:0006518 80 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
nucleoside metabolic process GO:0009116 127 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
positive regulation of molecular function GO:0044093 136 0.014
nitrogen compound transport GO:0071705 85 0.014
phagocytosis GO:0006909 215 0.014
response to biotic stimulus GO:0009607 294 0.014
glutathione metabolic process GO:0006749 37 0.014
pyridine containing compound metabolic process GO:0072524 3 0.014
regulation of cellular localization GO:0060341 136 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
nucleobase containing compound transport GO:0015931 56 0.014
negative regulation of gene expression GO:0010629 387 0.013
transmembrane transport GO:0055085 139 0.013
single organism biosynthetic process GO:0044711 206 0.013
pigmentation GO:0043473 75 0.013
neuron projection guidance GO:0097485 241 0.013
death GO:0016265 284 0.013
respiratory system development GO:0060541 213 0.013
mitotic spindle organization GO:0007052 220 0.013
organophosphate metabolic process GO:0019637 195 0.013
neurological system process GO:0050877 358 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
ion transmembrane transport GO:0034220 122 0.013
protein targeting to mitochondrion GO:0006626 1 0.013
regulation of immune system process GO:0002682 176 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
response to decreased oxygen levels GO:0036293 58 0.012
rna localization GO:0006403 115 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
rna processing GO:0006396 147 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
oocyte axis specification GO:0007309 108 0.012
eye pigment biosynthetic process GO:0006726 32 0.012
intracellular signal transduction GO:0035556 300 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
chromatin organization GO:0006325 207 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
chromosome organization GO:0051276 360 0.012
forebrain development GO:0030900 2 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
gland development GO:0048732 191 0.012
nucleotide metabolic process GO:0009117 161 0.012
response to organophosphorus GO:0046683 2 0.011
developmental pigmentation GO:0048066 68 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
protein complex assembly GO:0006461 200 0.011
glycoprotein metabolic process GO:0009100 41 0.011
purine containing compound metabolic process GO:0072521 155 0.011
negative regulation of signal transduction GO:0009968 206 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
xenobiotic catabolic process GO:0042178 1 0.011
response to hypoxia GO:0001666 53 0.011
retina development in camera type eye GO:0060041 4 0.011
protein glycosylation GO:0006486 32 0.011
amine metabolic process GO:0009308 12 0.011
regulation of cell death GO:0010941 173 0.011
positive regulation of cell migration GO:0030335 2 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
chaeta development GO:0022416 97 0.011
regulation of nervous system development GO:0051960 248 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
regulation of multi organism process GO:0043900 131 0.010
single organism intracellular transport GO:1902582 207 0.010
metal ion homeostasis GO:0055065 44 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
brain development GO:0007420 120 0.010
negative regulation of cell communication GO:0010648 223 0.010
positive regulation of lipid metabolic process GO:0045834 4 0.010
response to starvation GO:0042594 97 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010

Pbgs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of metabolism DOID:0014667 0 0.013
nervous system disease DOID:863 0 0.011