Drosophila melanogaster

47 known processes

scyl (Dmel_CG7590)

scylla

(Aliases: scy,CG7590,Dmel\CG7590,anon-WO0118547.215,7590)

scyl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.765
Mouse
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 5 0.738
Mouse
cellular carbohydrate metabolic process GO:0044262 22 0.509
Mouse
negative regulation of growth GO:0045926 84 0.488
death GO:0016265 284 0.468
programmed cell death GO:0012501 257 0.445
negative regulation of cellular metabolic process GO:0031324 382 0.435
Mouse
apoptotic signaling pathway GO:0097190 27 0.361
Mouse
regulation of growth GO:0040008 233 0.358
cellular response to dna damage stimulus GO:0006974 223 0.306
response to organic substance GO:0010033 284 0.299
apoptotic process GO:0006915 159 0.276
cell death GO:0008219 279 0.268
energy derivation by oxidation of organic compounds GO:0015980 32 0.263
cellular response to chemical stimulus GO:0070887 199 0.201
cellular response to organonitrogen compound GO:0071417 36 0.200
cellular respiration GO:0045333 26 0.194
imaginal disc derived appendage morphogenesis GO:0035114 395 0.171
enzyme linked receptor protein signaling pathway GO:0007167 179 0.163
carbohydrate metabolic process GO:0005975 82 0.157
Mouse
regulation of cellular response to insulin stimulus GO:1900076 17 0.150
tor signaling GO:0031929 32 0.149
cellular protein modification process GO:0006464 438 0.149
growth GO:0040007 359 0.149
small molecule metabolic process GO:0044281 305 0.146
Mouse
protein phosphorylation GO:0006468 169 0.137
regulation of apoptotic process GO:0042981 130 0.122
negative regulation of signaling GO:0023057 219 0.120
Human Mouse
regulation of tor signaling GO:0032006 21 0.119
carbohydrate catabolic process GO:0016052 7 0.116
Mouse
positive regulation of developmental process GO:0051094 143 0.115
response to nitrogen compound GO:1901698 90 0.114
transmembrane transport GO:0055085 139 0.114
single organism biosynthetic process GO:0044711 206 0.114
cellular carbohydrate catabolic process GO:0044275 2 0.110
Mouse
signal transduction by p53 class mediator GO:0072331 6 0.109
Mouse
cellular response to insulin stimulus GO:0032869 28 0.108
cellular response to organic substance GO:0071310 132 0.107
regulation of cell death GO:0010941 173 0.106
response to oxygen containing compound GO:1901700 200 0.103
response to insulin GO:0032868 29 0.103
positive regulation of macromolecule metabolic process GO:0010604 405 0.100
positive regulation of protein metabolic process GO:0051247 128 0.099
organic substance catabolic process GO:1901575 308 0.098
Mouse
embryonic morphogenesis GO:0048598 206 0.098
intracellular signal transduction GO:0035556 300 0.097
response to decreased oxygen levels GO:0036293 58 0.092
Human Mouse
negative regulation of heart rate GO:0010459 3 0.090
response to biotic stimulus GO:0009607 294 0.085
protein modification process GO:0036211 438 0.084
single organism carbohydrate metabolic process GO:0044723 72 0.083
Mouse
response to other organism GO:0051707 293 0.080
negative regulation of signal transduction GO:0009968 206 0.080
Human Mouse
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.078
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.075
positive regulation of cellular protein metabolic process GO:0032270 118 0.074
cellular catabolic process GO:0044248 372 0.073
Mouse
oxoacid metabolic process GO:0043436 103 0.072
Mouse
response to abiotic stimulus GO:0009628 341 0.071
Human Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.070
cell growth GO:0016049 108 0.067
response to external biotic stimulus GO:0043207 293 0.067
cell motility GO:0048870 251 0.067
cellular response to peptide GO:1901653 28 0.066
endocytosis GO:0006897 310 0.066
oxidation reduction process GO:0055114 123 0.066
regulation of cellular component biogenesis GO:0044087 201 0.065
camera type eye development GO:0043010 4 0.065
regulation of cell growth GO:0001558 43 0.065
response to endogenous stimulus GO:0009719 119 0.065
phosphorylation GO:0016310 294 0.065
response to bacterium GO:0009617 198 0.064
phagocytosis GO:0006909 215 0.064
regulation of programmed cell death GO:0043067 152 0.064
regulation of cellular carbohydrate metabolic process GO:0010675 7 0.064
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.064
homeostatic process GO:0042592 199 0.062
catabolic process GO:0009056 409 0.062
Mouse
regulation of cell proliferation GO:0042127 163 0.060
response to oxygen levels GO:0070482 59 0.060
Human Mouse
response to alcohol GO:0097305 95 0.059
cellular response to radiation GO:0071478 52 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.057
cell migration GO:0016477 238 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
localization of cell GO:0051674 257 0.051
cellular component disassembly GO:0022411 46 0.051
Mouse
defense response GO:0006952 300 0.051
embryo development ending in birth or egg hatching GO:0009792 152 0.051
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
monocarboxylic acid metabolic process GO:0032787 29 0.050
Mouse
synaptic growth at neuromuscular junction GO:0051124 119 0.049
cellular response to light stimulus GO:0071482 37 0.049
cell cycle phase transition GO:0044770 140 0.049
mitochondrion organization GO:0007005 65 0.048
regulation of phosphate metabolic process GO:0019220 210 0.048
regulation of catalytic activity GO:0050790 185 0.048
regulation of cell cycle GO:0051726 291 0.048
regulation of phosphorus metabolic process GO:0051174 210 0.047
generation of precursor metabolites and energy GO:0006091 42 0.047
Mouse
negative regulation of cell death GO:0060548 81 0.047
aging GO:0007568 143 0.047
cellular macromolecule localization GO:0070727 220 0.047
positive regulation of signaling GO:0023056 243 0.047
response to hormone GO:0009725 45 0.046
positive regulation of multicellular organismal process GO:0051240 143 0.046
regulation of molecular function GO:0065009 217 0.046
response to peptide GO:1901652 29 0.045
reactive oxygen species metabolic process GO:0072593 22 0.045
Mouse
positive regulation of reproductive process GO:2000243 7 0.044
regionalization GO:0003002 416 0.044
Zebrafish
negative regulation of catabolic process GO:0009895 36 0.043
Mouse
cellular response to hormone stimulus GO:0032870 44 0.043
dna damage checkpoint GO:0000077 78 0.042
negative regulation of gene expression GO:0010629 387 0.042
cellular response to endogenous stimulus GO:0071495 80 0.042
positive regulation of signal transduction GO:0009967 223 0.041
cellular protein localization GO:0034613 160 0.041
organic substance transport GO:0071702 257 0.040
organelle localization GO:0051640 148 0.040
regulation of nervous system development GO:0051960 248 0.040
positive regulation of response to stimulus GO:0048584 323 0.040
inositol lipid mediated signaling GO:0048017 4 0.039
g protein coupled receptor signaling pathway GO:0007186 136 0.039
mitochondrion distribution GO:0048311 10 0.038
positive regulation of protein modification process GO:0031401 58 0.038
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
regulation of protein modification process GO:0031399 112 0.036
dna integrity checkpoint GO:0031570 81 0.036
single organism catabolic process GO:0044712 228 0.036
Mouse
actin cytoskeleton organization GO:0030036 206 0.035
negative regulation of programmed cell death GO:0043069 72 0.035
determination of adult lifespan GO:0008340 137 0.035
regulation of phosphorylation GO:0042325 147 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
negative regulation of cell communication GO:0010648 223 0.034
Human Mouse
response to hypoxia GO:0001666 53 0.033
Human Mouse
regulation of mitotic cell cycle phase transition GO:1901990 130 0.033
intracellular protein transport GO:0006886 104 0.033
small gtpase mediated signal transduction GO:0007264 88 0.033
intracellular transport GO:0046907 228 0.032
regulation of cellular component size GO:0032535 98 0.032
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.031
regulation of catabolic process GO:0009894 170 0.031
Mouse
protein import into nucleus GO:0006606 51 0.031
response to peptide hormone GO:0043434 29 0.031
carboxylic acid metabolic process GO:0019752 92 0.031
Mouse
establishment of localization in cell GO:0051649 402 0.030
insulin receptor signaling pathway GO:0008286 25 0.030
organelle fission GO:0048285 340 0.030
single organism cellular localization GO:1902580 180 0.030
positive regulation of programmed cell death GO:0043068 62 0.029
protein transport GO:0015031 155 0.029
camera type eye morphogenesis GO:0048593 2 0.029
regulation of response to stress GO:0080134 200 0.029
positive regulation of cell migration GO:0030335 2 0.028
ion transport GO:0006811 145 0.028
response to oxidative stress GO:0006979 86 0.028
regulation of mitotic cell cycle GO:0007346 190 0.028
imaginal disc derived appendage development GO:0048737 399 0.028
appendage morphogenesis GO:0035107 397 0.028
single organism intracellular transport GO:1902582 207 0.028
dephosphorylation GO:0016311 51 0.027
nuclear transport GO:0051169 72 0.027
forebrain development GO:0030900 2 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.026
negative regulation of intracellular signal transduction GO:1902532 57 0.026
Human Mouse
stem cell differentiation GO:0048863 117 0.026
regulation of chromosome organization GO:0033044 64 0.026
response to nutrient levels GO:0031667 114 0.026
positive regulation of cell development GO:0010720 61 0.026
wing disc morphogenesis GO:0007472 344 0.025
positive regulation of cell death GO:0010942 69 0.025
muscle structure development GO:0061061 224 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
humoral immune response GO:0006959 117 0.025
negative regulation of biosynthetic process GO:0009890 277 0.025
cellular polysaccharide metabolic process GO:0044264 11 0.024
activation of ras gtpase activity GO:0032856 6 0.024
positive regulation of cell communication GO:0010647 250 0.024
single organism nuclear import GO:1902593 51 0.024
negative regulation of apoptotic process GO:0043066 63 0.024
nucleocytoplasmic transport GO:0006913 72 0.024
positive regulation of catalytic activity GO:0043085 118 0.023
regulation of localization GO:0032879 275 0.023
glycolytic process GO:0006096 6 0.023
Mouse
negative regulation of translation GO:0017148 28 0.023
regulation of immune system process GO:0002682 176 0.023
regulation of defense response GO:0031347 102 0.023
negative regulation of rna metabolic process GO:0051253 251 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.023
positive regulation of molecular function GO:0044093 136 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.023
neuromuscular synaptic transmission GO:0007274 67 0.022
positive regulation of lipid catabolic process GO:0050996 1 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
larval midgut histolysis GO:0035069 22 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.022
organophosphate metabolic process GO:0019637 195 0.022
regulation of protein phosphorylation GO:0001932 64 0.022
cell cycle g1 s phase transition GO:0044843 31 0.021
metal ion transport GO:0030001 74 0.021
positive regulation of mitotic cell cycle GO:0045931 34 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
regulation of cell size GO:0008361 63 0.021
retina development in camera type eye GO:0060041 4 0.021
defense response to bacterium GO:0042742 178 0.021
mesenchymal cell development GO:0014031 1 0.021
polysaccharide metabolic process GO:0005976 11 0.020
cell division GO:0051301 248 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.020
positive regulation of cell cycle GO:0045787 43 0.020
regulation of lipid metabolic process GO:0019216 15 0.020
macromolecular complex assembly GO:0065003 256 0.020
immune system development GO:0002520 57 0.019
extrinsic apoptotic signaling pathway GO:0097191 1 0.019
synapse organization GO:0050808 196 0.019
neural precursor cell proliferation GO:0061351 75 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
response to lipid GO:0033993 38 0.019
cellular response to decreased oxygen levels GO:0036294 30 0.019
pyruvate metabolic process GO:0006090 7 0.019
Mouse
negative regulation of response to stimulus GO:0048585 258 0.019
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
regulation of organelle organization GO:0033043 196 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
regulation of anatomical structure size GO:0090066 163 0.018
cellular response to growth factor stimulus GO:0071363 30 0.018
nuclear division GO:0000280 332 0.018
response to ketone GO:1901654 34 0.018
regulation of meiosis GO:0040020 3 0.018
gene silencing GO:0016458 138 0.017
monocarboxylic acid transport GO:0015718 3 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
multicellular organism growth GO:0035264 46 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
regulation of immune response GO:0050776 118 0.017
regulation of cell cycle g1 s phase transition GO:1902806 23 0.017
regulation of cell cycle process GO:0010564 181 0.017
myotube cell development GO:0014904 3 0.017
mitotic nuclear division GO:0007067 213 0.017
positive regulation of cell motility GO:2000147 3 0.017
semaphorin plexin signaling pathway GO:0071526 4 0.016
establishment of protein localization GO:0045184 163 0.016
regulation of mrna 3 end processing GO:0031440 7 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
regulation of multicellular organism growth GO:0040014 40 0.016
organelle assembly GO:0070925 198 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
positive regulation of defense response GO:0031349 59 0.016
muscle organ development GO:0007517 127 0.016
developmental pigmentation GO:0048066 68 0.016
macromolecular complex disassembly GO:0032984 37 0.016
Mouse
positive regulation of insulin receptor signaling pathway GO:0046628 3 0.016
regulation of response to external stimulus GO:0032101 115 0.016
cellular response to peptide hormone stimulus GO:0071375 28 0.016
autophagic vacuole assembly GO:0000045 2 0.016
positive regulation of gene expression GO:0010628 290 0.016
regulation of gene silencing GO:0060968 63 0.016
response to organonitrogen compound GO:0010243 75 0.016
g1 s transition of mitotic cell cycle GO:0000082 31 0.016
phosphatidylinositol mediated signaling GO:0048015 4 0.016
response to wounding GO:0009611 94 0.016
cation homeostasis GO:0055080 51 0.016
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.015
immune system process GO:0002376 347 0.015
cell type specific apoptotic process GO:0097285 38 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
protein catabolic process GO:0030163 101 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
ameboidal type cell migration GO:0001667 151 0.015
cytoplasmic transport GO:0016482 130 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
actin filament based process GO:0030029 220 0.015
response to extracellular stimulus GO:0009991 116 0.015
response to temperature stimulus GO:0009266 106 0.015
chemical homeostasis GO:0048878 92 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
Mouse
immune response GO:0006955 246 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
response to lipopolysaccharide GO:0032496 4 0.015
positive regulation of cell size GO:0045793 21 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
protein targeting to nucleus GO:0044744 51 0.015
mitotic cell cycle phase transition GO:0044772 138 0.014
positive regulation of growth GO:0045927 75 0.014
cellular response to nitrogen compound GO:1901699 51 0.014
response to paraquat GO:1901562 4 0.014
digestive system development GO:0055123 149 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
positive regulation of nurse cell apoptotic process GO:0045850 5 0.014
skeletal muscle fiber development GO:0048741 3 0.014
cell proliferation GO:0008283 299 0.014
appendage development GO:0048736 401 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
body morphogenesis GO:0010171 2 0.014
regulation of developmental growth GO:0048638 174 0.014
divalent metal ion transport GO:0070838 26 0.014
autophagy GO:0006914 108 0.014
smoothened signaling pathway GO:0007224 49 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
lipid localization GO:0010876 54 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
lipid metabolic process GO:0006629 121 0.013
regulation of response to extracellular stimulus GO:0032104 18 0.013
regulation of mapk cascade GO:0043408 92 0.013
striated muscle adaptation GO:0014888 1 0.013
regulation of cellular localization GO:0060341 136 0.013
peptidyl threonine phosphorylation GO:0018107 2 0.013
response to hexose GO:0009746 3 0.013
positive regulation of glycogen biosynthetic process GO:0045725 1 0.013
dna replication GO:0006260 48 0.013
establishment of epithelial cell polarity GO:0090162 13 0.013
cellular response to abiotic stimulus GO:0071214 58 0.013
regulation of carbohydrate metabolic process GO:0006109 10 0.012
Mouse
response to growth factor GO:0070848 31 0.012
spinal cord development GO:0021510 1 0.012
negative regulation of immune system process GO:0002683 50 0.012
mitotic spindle organization GO:0007052 220 0.012
regulation of autophagy GO:0010506 62 0.012
gland development GO:0048732 191 0.012
positive regulation of lipid biosynthetic process GO:0046889 3 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
chaeta development GO:0022416 97 0.012
salivary gland development GO:0007431 162 0.012
tissue migration GO:0090130 155 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
neuron death GO:0070997 27 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
innate immune response GO:0045087 144 0.012
regulation of transport GO:0051049 181 0.012
cell cycle dna replication GO:0044786 23 0.011
regulation of synapse organization GO:0050807 110 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
regulation of innate immune response GO:0045088 71 0.011
regulation of protein localization GO:0032880 76 0.011
lipid biosynthetic process GO:0008610 46 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
protein localization to organelle GO:0033365 82 0.011
ras protein signal transduction GO:0007265 88 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
divalent inorganic cation transport GO:0072511 30 0.011
regulation of transferase activity GO:0051338 58 0.011
regulation of response to nutrient levels GO:0032107 18 0.011
developmental programmed cell death GO:0010623 138 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of intracellular transport GO:0032386 64 0.011
maintenance of gastrointestinal epithelium GO:0030277 3 0.011
glycerolipid metabolic process GO:0046486 34 0.011
regulation of cell differentiation GO:0045595 302 0.011
mapk cascade GO:0000165 107 0.011
vesicle mediated transport GO:0016192 381 0.011
defense response to other organism GO:0098542 225 0.011
actin cytoskeleton reorganization GO:0031532 22 0.011
nuclear import GO:0051170 51 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
developmental growth GO:0048589 280 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
wound healing GO:0042060 75 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
Zebrafish

scyl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org