Drosophila melanogaster

8 known processes

PGRP-LA (Dmel_CG32042)

Peptidoglycan recognition protein LA

(Aliases: Dmel\CG32042,CG4361,CG18614,CG32042,CG4384,PGRPLA)

PGRP-LA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external biotic stimulus GO:0043207 293 0.167
response to bacterium GO:0009617 198 0.137
response to biotic stimulus GO:0009607 294 0.124
defense response GO:0006952 300 0.090
defense response to bacterium GO:0042742 178 0.086
growth GO:0040007 359 0.085
developmental growth GO:0048589 280 0.084
response to other organism GO:0051707 293 0.080
defense response to other organism GO:0098542 225 0.075
epithelial cell development GO:0002064 274 0.063
organelle fission GO:0048285 340 0.061
small molecule metabolic process GO:0044281 305 0.057
immune system process GO:0002376 347 0.055
intracellular signal transduction GO:0035556 300 0.054
defense response to gram negative bacterium GO:0050829 94 0.054
innate immune response GO:0045087 144 0.054
single organism behavior GO:0044708 391 0.053
organonitrogen compound metabolic process GO:1901564 318 0.053
catabolic process GO:0009056 409 0.050
regulation of response to stress GO:0080134 200 0.050
proteolysis GO:0006508 192 0.048
response to abiotic stimulus GO:0009628 341 0.046
regulation of intracellular signal transduction GO:1902531 236 0.046
cellular catabolic process GO:0044248 372 0.045
organic substance catabolic process GO:1901575 308 0.040
nuclear division GO:0000280 332 0.040
ovarian follicle cell development GO:0030707 248 0.039
synapse assembly GO:0007416 143 0.039
transmembrane transport GO:0055085 139 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.037
regulation of multicellular organismal development GO:2000026 414 0.037
regulation of growth GO:0040008 233 0.037
nucleoside phosphate metabolic process GO:0006753 162 0.037
chromosome segregation GO:0007059 157 0.036
organic cyclic compound catabolic process GO:1901361 168 0.035
imaginal disc derived appendage morphogenesis GO:0035114 395 0.035
sensory perception of smell GO:0007608 80 0.035
epithelial cell differentiation GO:0030855 322 0.035
cellular protein modification process GO:0006464 438 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
negative regulation of multicellular organismal process GO:0051241 142 0.034
sensory perception GO:0007600 196 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
appendage development GO:0048736 401 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
response to light stimulus GO:0009416 124 0.033
response to radiation GO:0009314 155 0.033
imaginal disc derived leg morphogenesis GO:0007480 80 0.033
forebrain development GO:0030900 2 0.032
single organism catabolic process GO:0044712 228 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
axis specification GO:0009798 167 0.032
neurological system process GO:0050877 358 0.031
regulation of developmental growth GO:0048638 174 0.031
ion transport GO:0006811 145 0.030
organic hydroxy compound metabolic process GO:1901615 83 0.030
adult behavior GO:0030534 137 0.030
establishment of localization in cell GO:0051649 402 0.030
proteasomal protein catabolic process GO:0010498 59 0.030
actin cytoskeleton organization GO:0030036 206 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.029
regulation of innate immune response GO:0045088 71 0.029
positive regulation of response to stimulus GO:0048584 323 0.028
regulation of nervous system development GO:0051960 248 0.028
leg disc development GO:0035218 92 0.027
tube development GO:0035295 244 0.027
regulation of anatomical structure size GO:0090066 163 0.027
wing disc morphogenesis GO:0007472 344 0.027
ribonucleoside catabolic process GO:0042454 112 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
open tracheal system development GO:0007424 204 0.026
polyol biosynthetic process GO:0046173 3 0.026
appendage morphogenesis GO:0035107 397 0.026
regulation of cell cycle GO:0051726 291 0.025
tissue morphogenesis GO:0048729 297 0.025
salivary gland development GO:0007431 162 0.025
toxin catabolic process GO:0009407 1 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
response to temperature stimulus GO:0009266 106 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
leg disc morphogenesis GO:0007478 80 0.024
positive regulation of cell motility GO:2000147 3 0.024
developmental programmed cell death GO:0010623 138 0.023
meiotic cell cycle process GO:1903046 132 0.023
localization of cell GO:0051674 257 0.023
macromolecule catabolic process GO:0009057 161 0.023
positive regulation of immune system process GO:0002684 68 0.023
steroid catabolic process GO:0006706 1 0.023
response to organic substance GO:0010033 284 0.023
kidney development GO:0001822 3 0.023
synaptic transmission GO:0007268 288 0.022
regulation of cell projection organization GO:0031344 92 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
regulation of cell development GO:0060284 215 0.022
cell adhesion involved in heart morphogenesis GO:0061343 12 0.022
eggshell formation GO:0030703 105 0.022
mitotic cell cycle phase transition GO:0044772 138 0.022
cation transport GO:0006812 110 0.022
response to lipopolysaccharide GO:0032496 4 0.022
ras protein signal transduction GO:0007265 88 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
single organism biosynthetic process GO:0044711 206 0.022
response to organophosphorus GO:0046683 2 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
positive regulation of signal transduction GO:0009967 223 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
regulation of immune system process GO:0002682 176 0.021
sensory perception of chemical stimulus GO:0007606 116 0.021
nitrogen compound transport GO:0071705 85 0.021
regulation of tube architecture open tracheal system GO:0035152 68 0.021
ameboidal type cell migration GO:0001667 151 0.021
histolysis GO:0007559 102 0.021
immune response GO:0006955 246 0.021
positive regulation of cell migration GO:0030335 2 0.021
ion transmembrane transport GO:0034220 122 0.021
cellular ketone metabolic process GO:0042180 24 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
positive regulation of cell communication GO:0010647 250 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
negative regulation of developmental process GO:0051093 201 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
mitotic nuclear division GO:0007067 213 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
regulation of tube size GO:0035150 46 0.020
vitamin biosynthetic process GO:0009110 1 0.020
protein catabolic process GO:0030163 101 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
regulation of synapse organization GO:0050807 110 0.020
regulation of cell differentiation GO:0045595 302 0.020
l amino acid import GO:0043092 2 0.020
regionalization GO:0003002 416 0.019
respiratory system development GO:0060541 213 0.019
organic substance transport GO:0071702 257 0.019
behavioral response to ethanol GO:0048149 49 0.019
purine containing compound metabolic process GO:0072521 155 0.019
purine containing compound catabolic process GO:0072523 112 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
programmed cell death GO:0012501 257 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
nucleoside catabolic process GO:0009164 112 0.019
xenobiotic catabolic process GO:0042178 1 0.019
rna processing GO:0006396 147 0.019
actin filament based process GO:0030029 220 0.019
chromosome organization GO:0051276 360 0.019
developmental maturation GO:0021700 172 0.019
meiotic nuclear division GO:0007126 151 0.018
ecdysteroid biosynthetic process GO:0045456 15 0.018
lipid metabolic process GO:0006629 121 0.018
central nervous system development GO:0007417 201 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
protein localization GO:0008104 284 0.018
pattern recognition receptor signaling pathway GO:0002221 2 0.018
exocrine system development GO:0035272 162 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
ketone biosynthetic process GO:0042181 16 0.018
immune response regulating signaling pathway GO:0002764 2 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.017
segmentation GO:0035282 207 0.017
centrosome cycle GO:0007098 137 0.017
aggressive behavior GO:0002118 63 0.017
innate immune response activating signal transduction GO:0002758 2 0.017
cell cycle phase transition GO:0044770 140 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
salivary gland morphogenesis GO:0007435 145 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
eye development GO:0001654 323 0.017
salivary gland histolysis GO:0035070 88 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
antibacterial humoral response GO:0019731 44 0.017
regulation of cell death GO:0010941 173 0.017
cellular protein catabolic process GO:0044257 83 0.017
protein complex assembly GO:0006461 200 0.017
insecticide catabolic process GO:0046701 1 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
phagocytosis GO:0006909 215 0.016
tissue death GO:0016271 102 0.016
dorsal closure GO:0007391 79 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
regulation of catalytic activity GO:0050790 185 0.016
chromosome separation GO:0051304 42 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
positive regulation of signaling GO:0023056 243 0.016
cell motility GO:0048870 251 0.016
cell death GO:0008219 279 0.016
tissue migration GO:0090130 155 0.016
organophosphate metabolic process GO:0019637 195 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
meiotic cell cycle GO:0051321 171 0.016
spindle organization GO:0007051 253 0.016
autophagic cell death GO:0048102 83 0.016
positive regulation of catalytic activity GO:0043085 118 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
developmental cell growth GO:0048588 52 0.015
ovarian follicle cell migration GO:0007297 121 0.015
dna packaging GO:0006323 91 0.015
regulation of catabolic process GO:0009894 170 0.015
cuticle development GO:0042335 86 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
chemotaxis GO:0006935 249 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.015
nucleotide catabolic process GO:0009166 109 0.015
telencephalon development GO:0021537 2 0.015
regulation of cellular response to stress GO:0080135 89 0.015
medium chain fatty acid metabolic process GO:0051791 1 0.015
multi organism reproductive behavior GO:0044705 121 0.015
protein modification process GO:0036211 438 0.015
gland morphogenesis GO:0022612 145 0.015
apical junction assembly GO:0043297 32 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
autophagy GO:0006914 108 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.014
mating GO:0007618 120 0.014
metal ion transport GO:0030001 74 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
endocytosis GO:0006897 310 0.014
axonogenesis GO:0007409 290 0.014
multi organism behavior GO:0051705 175 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
regulation of jnk cascade GO:0046328 40 0.014
response to insecticide GO:0017085 14 0.014
septate junction assembly GO:0019991 26 0.014
embryonic morphogenesis GO:0048598 206 0.014
vitamin metabolic process GO:0006766 2 0.014
lauric acid metabolic process GO:0048252 1 0.014
taxis GO:0042330 304 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
regulation of response to external stimulus GO:0032101 115 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
epithelium migration GO:0090132 148 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
establishment of planar polarity GO:0001736 87 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
ecdysteroid metabolic process GO:0045455 19 0.014
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
mitotic spindle organization GO:0007052 220 0.013
aromatic compound catabolic process GO:0019439 166 0.013
embryonic pattern specification GO:0009880 174 0.013
response to organic cyclic compound GO:0014070 89 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of organelle organization GO:0033043 196 0.013
activation of innate immune response GO:0002218 4 0.013
reproductive behavior GO:0019098 122 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
androgen metabolic process GO:0008209 1 0.013
gland development GO:0048732 191 0.013
centrosome organization GO:0051297 163 0.013
multi multicellular organism process GO:0044706 123 0.013
axon development GO:0061564 297 0.013
regulation of cell shape GO:0008360 113 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of immune response GO:0050776 118 0.013
neuromuscular junction development GO:0007528 149 0.013
dna metabolic process GO:0006259 227 0.013
cellular amide metabolic process GO:0043603 80 0.013
dorsal ventral axis specification GO:0009950 66 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
regulation of hormone levels GO:0010817 40 0.013
humoral immune response GO:0006959 117 0.013
gene silencing GO:0016458 138 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
oxidation reduction process GO:0055114 123 0.013
biological adhesion GO:0022610 138 0.013
response to oxygen containing compound GO:1901700 200 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of response to external stimulus GO:0032103 44 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
cell proliferation GO:0008283 299 0.013
jnk cascade GO:0007254 50 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.012
body morphogenesis GO:0010171 2 0.012
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
rho protein signal transduction GO:0007266 14 0.012
epithelial cell migration GO:0010631 148 0.012
phosphorylation GO:0016310 294 0.012
cytokinesis GO:0000910 90 0.012
protein maturation GO:0051604 71 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
hormone metabolic process GO:0042445 33 0.012
nucleotide metabolic process GO:0009117 161 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of defense response GO:0031347 102 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
mapk cascade GO:0000165 107 0.012
regulation of antimicrobial peptide production GO:0002784 44 0.012
l glutamate import GO:0051938 1 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
cell migration GO:0016477 238 0.012
response to wounding GO:0009611 94 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
organophosphate catabolic process GO:0046434 112 0.012
cellular homeostasis GO:0019725 80 0.012
positive regulation of molecular function GO:0044093 136 0.012
camera type eye development GO:0043010 4 0.012
regulation of rho gtpase activity GO:0032319 20 0.012
amide biosynthetic process GO:0043604 42 0.012
antimicrobial peptide production GO:0002775 46 0.012
regulation of cellular amide metabolic process GO:0034248 39 0.012
centrosome duplication GO:0051298 121 0.012
molting cycle GO:0042303 56 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
regulation of localization GO:0032879 275 0.011
positive regulation of defense response GO:0031349 59 0.011
cell maturation GO:0048469 144 0.011
digestive tract development GO:0048565 149 0.011
protein alkylation GO:0008213 43 0.011
connective tissue development GO:0061448 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
actin filament organization GO:0007015 126 0.011
protein processing GO:0016485 68 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
negative regulation of nervous system development GO:0051961 92 0.011
negative regulation of cell communication GO:0010648 223 0.011
compound eye development GO:0048749 307 0.011
compound eye morphogenesis GO:0001745 249 0.011
meiotic chromosome segregation GO:0045132 59 0.011
histone modification GO:0016570 106 0.011
dephosphorylation GO:0016311 51 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
muscle organ development GO:0007517 127 0.011
nucleoside metabolic process GO:0009116 127 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
meiosis i GO:0007127 59 0.011
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.011
anion transport GO:0006820 41 0.011
learning or memory GO:0007611 141 0.011
death GO:0016265 284 0.011
imaginal disc pattern formation GO:0007447 91 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
regulation of programmed cell death GO:0043067 152 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
antimicrobial humoral response GO:0019730 99 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010
embryonic axis specification GO:0000578 107 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
wound healing GO:0042060 75 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of transport GO:0051049 181 0.010
oxoacid metabolic process GO:0043436 103 0.010
mating behavior GO:0007617 106 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
positive regulation of developmental process GO:0051094 143 0.010
detection of external stimulus GO:0009581 66 0.010
regulation of production of molecular mediator of immune response GO:0002700 44 0.010
gliogenesis GO:0042063 80 0.010
courtship behavior GO:0007619 68 0.010
protein complex biogenesis GO:0070271 201 0.010
response to ethanol GO:0045471 59 0.010
negative regulation of growth GO:0045926 84 0.010
blastoderm segmentation GO:0007350 159 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
cell projection assembly GO:0030031 94 0.010

PGRP-LA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.122
urinary system disease DOID:18 0 0.026
hypertension DOID:10763 0 0.021
artery disease DOID:0050828 0 0.021
vascular disease DOID:178 0 0.021
essential hypertension DOID:10825 0 0.021
cardiovascular system disease DOID:1287 0 0.021
nervous system disease DOID:863 0 0.014
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
kidney disease DOID:557 0 0.013
disease of metabolism DOID:0014667 0 0.013
renal tubular transport disease DOID:447 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011