Drosophila melanogaster

246 known processes

wts (Dmel_CG12072)

warts

(Aliases: MENE (3R)-G,CG12072,Wts,wart,LATS,Lats,warts/lats,Warts/Lats,l(3)100Aa,lats,WTS/LATS,Wts/Lats,Dmel\CG12072,Dlats,wts/lats,Lats/Warts,Warts,lts,dmLATS)

wts biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of organ growth GO:0046621 15 0.985
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.976
compound eye morphogenesis GO:0001745 249 0.971
epithelial cell differentiation GO:0030855 322 0.968
eye development GO:0001654 323 0.966
growth GO:0040007 359 0.965
negative regulation of signal transduction GO:0009968 206 0.957
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.957
ovarian follicle cell development GO:0030707 248 0.952
localization of cell GO:0051674 257 0.951
negative regulation of response to stimulus GO:0048585 258 0.948
negative regulation of cell communication GO:0010648 223 0.940
positive regulation of macromolecule metabolic process GO:0010604 405 0.925
Human
compound eye development GO:0048749 307 0.924
regulation of protein metabolic process GO:0051246 256 0.918
Human
regulation of growth GO:0040008 233 0.916
Mouse
regulation of organ growth GO:0046620 42 0.908
Mouse
cell motility GO:0048870 251 0.901
compound eye photoreceptor cell differentiation GO:0001751 140 0.887
eye photoreceptor cell differentiation GO:0001754 145 0.886
tube morphogenesis GO:0035239 191 0.883
Worm
eye morphogenesis GO:0048592 260 0.875
regulation of cell proliferation GO:0042127 163 0.870
developmental growth GO:0048589 280 0.868
columnar cuboidal epithelial cell development GO:0002066 249 0.861
organ growth GO:0035265 56 0.855
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.838
hippo signaling GO:0035329 20 0.834
Human Mouse
ovarian follicle cell migration GO:0007297 121 0.829
regulation of intracellular signal transduction GO:1902531 236 0.825
intracellular signal transduction GO:0035556 300 0.808
sensory organ morphogenesis GO:0090596 260 0.798
regulation of developmental growth GO:0048638 174 0.794
Mouse
axon development GO:0061564 297 0.791
cell migration GO:0016477 238 0.761
regulation of hippo signaling GO:0035330 14 0.760
regulation of imaginal disc growth GO:0045570 26 0.760
negative regulation of glial cell proliferation GO:0060253 6 0.758
positive regulation of cellular protein metabolic process GO:0032270 118 0.736
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.713
response to radiation GO:0009314 155 0.712
negative regulation of gene expression GO:0010629 387 0.711
tube development GO:0035295 244 0.698
Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.691
actin cytoskeleton organization GO:0030036 206 0.678
Human
positive regulation of protein modification process GO:0031401 58 0.675
Human
open tracheal system development GO:0007424 204 0.666
regulation of wnt signaling pathway GO:0030111 68 0.630
gliogenesis GO:0042063 80 0.619
programmed cell death GO:0012501 257 0.605
border follicle cell migration GO:0007298 113 0.581
cell growth GO:0016049 108 0.581
actin filament organization GO:0007015 126 0.581
Human
negative regulation of rna metabolic process GO:0051253 251 0.576
negative regulation of cellular biosynthetic process GO:0031327 277 0.565
photoreceptor cell differentiation GO:0046530 170 0.556
negative regulation of imaginal disc growth GO:0045571 8 0.545
negative regulation of cellular metabolic process GO:0031324 382 0.545
regulation of epithelial cell proliferation GO:0050678 4 0.544
protein phosphorylation GO:0006468 169 0.542
Human Mouse
regulation of apoptotic process GO:0042981 130 0.540
enzyme linked receptor protein signaling pathway GO:0007167 179 0.534
establishment of localization in cell GO:0051649 402 0.520
striated muscle tissue development GO:0014706 27 0.519
cellular ketone metabolic process GO:0042180 24 0.509
regulation of cellular amino acid metabolic process GO:0006521 0 0.504
cellular response to endogenous stimulus GO:0071495 80 0.494
Human Mouse
negative regulation of wnt signaling pathway GO:0030178 28 0.483
response to organic substance GO:0010033 284 0.482
Human Mouse
trachea morphogenesis GO:0060439 22 0.467
tissue homeostasis GO:0001894 36 0.462
positive regulation of endopeptidase activity GO:0010950 26 0.460
negative regulation of signaling GO:0023057 219 0.459
positive regulation of molecular function GO:0044093 136 0.457
epithelial cell development GO:0002064 274 0.453
response to oxidative stress GO:0006979 86 0.449
branching morphogenesis of an epithelial tube GO:0048754 45 0.443
proteolysis GO:0006508 192 0.439
imaginal disc growth GO:0007446 37 0.432
phosphorylation GO:0016310 294 0.415
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.415
Human
cellular response to chemical stimulus GO:0070887 199 0.414
Human Mouse
muscle tissue development GO:0060537 30 0.413
regulation of cell morphogenesis GO:0022604 163 0.411
negative regulation of transcription dna templated GO:0045892 237 0.401
positive regulation of proteolysis GO:0045862 52 0.399
regulation of cell death GO:0010941 173 0.393
eye photoreceptor cell fate commitment GO:0042706 37 0.393
positive regulation of programmed cell death GO:0043068 62 0.387
organic substance transport GO:0071702 257 0.383
Human
erbb signaling pathway GO:0038127 58 0.377
negative regulation of cell proliferation GO:0008285 69 0.371
positive regulation of protein metabolic process GO:0051247 128 0.371
Human
positive regulation of multicellular organismal process GO:0051240 143 0.367
regulation of molecular function GO:0065009 217 0.363
Human
cellular response to organic substance GO:0071310 132 0.360
Human Mouse
response to abiotic stimulus GO:0009628 341 0.358
regulation of mitotic cell cycle GO:0007346 190 0.357
epithelium migration GO:0090132 148 0.349
regulation of phosphorylation GO:0042325 147 0.349
Human
regulation of cell cycle GO:0051726 291 0.347
Human
oxoacid metabolic process GO:0043436 103 0.339
peptidyl lysine modification GO:0018205 57 0.334
regulation of glial cell proliferation GO:0060251 11 0.332
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.331
regulation of multicellular organismal development GO:2000026 414 0.328
death GO:0016265 284 0.327
axonogenesis GO:0007409 290 0.325
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.323
regulation of stem cell proliferation GO:0072091 40 0.322
regulation of proteolysis GO:0030162 87 0.321
cellular amine metabolic process GO:0044106 12 0.317
response to endogenous stimulus GO:0009719 119 0.315
Human Mouse
regulation of cell development GO:0060284 215 0.308
nuclear transport GO:0051169 72 0.301
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.297
compound eye photoreceptor development GO:0042051 78 0.295
regulation of phosphorus metabolic process GO:0051174 210 0.292
Human
male gamete generation GO:0048232 201 0.289
regulation of cellular ketone metabolic process GO:0010565 3 0.286
protein modification process GO:0036211 438 0.285
Human Mouse
cell death GO:0008219 279 0.276
actin filament based process GO:0030029 220 0.275
Human
regulation of cysteine type endopeptidase activity GO:2000116 27 0.273
cellular protein modification process GO:0006464 438 0.263
Human Mouse
positive regulation of cell death GO:0010942 69 0.263
small gtpase mediated signal transduction GO:0007264 88 0.262
peptidyl amino acid modification GO:0018193 105 0.258
Human
apoptotic process GO:0006915 159 0.254
trachea development GO:0060438 29 0.247
posttranscriptional regulation of gene expression GO:0010608 145 0.246
tissue morphogenesis GO:0048729 297 0.242
regulation of transport GO:0051049 181 0.241
Human
respiratory system development GO:0060541 213 0.236
regulation of transferase activity GO:0051338 58 0.235
Human
cell competition in a multicellular organism GO:0035212 10 0.229
cellular amino acid metabolic process GO:0006520 61 0.229
digestive tract morphogenesis GO:0048546 127 0.223
Worm
positive regulation of transcription dna templated GO:0045893 266 0.221
protein modification by small protein conjugation or removal GO:0070647 106 0.216
negative regulation of intracellular signal transduction GO:1902532 57 0.216
catabolic process GO:0009056 409 0.213
regulation of catalytic activity GO:0050790 185 0.212
Human
regulation of cellular catabolic process GO:0031329 157 0.212
regulation of protein localization GO:0032880 76 0.207
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.200
negative regulation of growth GO:0045926 84 0.199
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.198
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.197
mitotic cell cycle embryonic GO:0045448 38 0.196
regulation of neurogenesis GO:0050767 158 0.192
epidermal growth factor receptor signaling pathway GO:0007173 58 0.188
developmental maturation GO:0021700 172 0.186
digestive tract development GO:0048565 149 0.184
Worm
cellular protein catabolic process GO:0044257 83 0.184
autophagy GO:0006914 108 0.182
terminal branching open tracheal system GO:0007430 17 0.181
establishment or maintenance of cell polarity GO:0007163 167 0.179
regulation of cytoskeleton organization GO:0051493 89 0.177
Human
positive regulation of autophagy GO:0010508 21 0.176
nucleocytoplasmic transport GO:0006913 72 0.176
positive regulation of signal transduction GO:0009967 223 0.174
cellular protein localization GO:0034613 160 0.173
Human Mouse
regulation of cell cycle process GO:0010564 181 0.172
regulation of protein ubiquitination GO:0031396 22 0.170
chromatin modification GO:0016568 147 0.168
morphogenesis of follicular epithelium GO:0016333 36 0.167
organic acid metabolic process GO:0006082 103 0.167
purine ribonucleotide catabolic process GO:0009154 109 0.167
regulation of canonical wnt signaling pathway GO:0060828 15 0.166
regulation of anatomical structure morphogenesis GO:0022603 242 0.165
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.165
establishment of epithelial cell apical basal polarity GO:0045198 10 0.164
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.162
response to ionizing radiation GO:0010212 32 0.160
cell fate specification GO:0001708 71 0.159
homeostatic process GO:0042592 199 0.158
regulation of protein modification process GO:0031399 112 0.156
Human
small molecule metabolic process GO:0044281 305 0.156
regulation of localization GO:0032879 275 0.154
Human
regulation of programmed cell death GO:0043067 152 0.153
protein localization GO:0008104 284 0.151
Human Mouse Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.151
urogenital system development GO:0001655 72 0.151
negative regulation of nucleic acid templated transcription GO:1903507 240 0.149
branching involved in open tracheal system development GO:0060446 45 0.145
regulation of protein transport GO:0051223 57 0.141
Human
endosomal transport GO:0016197 44 0.141
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.140
r3 r4 cell differentiation GO:0048056 12 0.139
positive regulation of peptidase activity GO:0010952 29 0.139
r7 cell differentiation GO:0045466 43 0.138
regulation of organelle organization GO:0033043 196 0.137
Human
positive regulation of gene expression GO:0010628 290 0.136
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.135
amine metabolic process GO:0009308 12 0.135
appendage morphogenesis GO:0035107 397 0.135
protein modification by small protein conjugation GO:0032446 79 0.134
regulation of cell cycle g1 s phase transition GO:1902806 23 0.134
sensory perception GO:0007600 196 0.133
regulation of actin cytoskeleton organization GO:0032956 42 0.131
Human
regulation of erbb signaling pathway GO:1901184 42 0.131
positive regulation of nucleic acid templated transcription GO:1903508 266 0.131
positive regulation of catalytic activity GO:0043085 118 0.130
maintenance of gastrointestinal epithelium GO:0030277 3 0.130
dendrite morphogenesis GO:0048813 199 0.130
protein catabolic process GO:0030163 101 0.128
negative regulation of cell cycle GO:0045786 116 0.126
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.126
regulation of organ morphogenesis GO:2000027 78 0.123
head development GO:0060322 135 0.117
cognition GO:0050890 141 0.117
morphogenesis of an epithelium GO:0002009 276 0.116
body morphogenesis GO:0010171 2 0.116
regulation of neuron death GO:1901214 26 0.116
eye photoreceptor cell development GO:0042462 81 0.116
renal system development GO:0072001 72 0.115
modification dependent macromolecule catabolic process GO:0043632 79 0.115
outflow tract morphogenesis GO:0003151 4 0.114
cytoplasmic transport GO:0016482 130 0.111
ras protein signal transduction GO:0007265 88 0.110
positive regulation of cellular amine metabolic process GO:0033240 0 0.109
regulation of cell differentiation GO:0045595 302 0.108
negative regulation of mitotic cell cycle GO:0045930 109 0.108
nucleoside triphosphate catabolic process GO:0009143 108 0.107
cellular response to dna damage stimulus GO:0006974 223 0.107
cellular catabolic process GO:0044248 372 0.107
neurological system process GO:0050877 358 0.106
regulation of cell growth GO:0001558 43 0.105
decapentaplegic signaling pathway GO:0008101 19 0.105
spermatid development GO:0007286 98 0.104
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.103
nucleoside phosphate metabolic process GO:0006753 162 0.103
neuron fate commitment GO:0048663 50 0.103
stem cell development GO:0048864 79 0.102
negative regulation of phosphorylation GO:0042326 35 0.102
Human
cell proliferation GO:0008283 299 0.101
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.099
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.098
histone modification GO:0016570 106 0.098
compound eye photoreceptor fate commitment GO:0001752 36 0.097
negative regulation of biosynthetic process GO:0009890 277 0.097
actomyosin structure organization GO:0031032 56 0.096
cardiac muscle tissue development GO:0048738 9 0.094
regulation of axonogenesis GO:0050770 32 0.093
regulation of r7 cell differentiation GO:0045676 15 0.093
canonical wnt signaling pathway GO:0060070 21 0.093
regulation of endopeptidase activity GO:0052548 36 0.092
positive regulation of intracellular signal transduction GO:1902533 116 0.091
negative regulation of cell differentiation GO:0045596 143 0.091
gene silencing GO:0016458 138 0.091
regulation of neuron apoptotic process GO:0043523 16 0.089
positive regulation of signaling GO:0023056 243 0.089
protein maturation GO:0051604 71 0.089
ribonucleotide catabolic process GO:0009261 109 0.089
regulation of response to nutrient levels GO:0032107 18 0.087
taxis GO:0042330 304 0.085
dna metabolic process GO:0006259 227 0.084
regulation of peptidase activity GO:0052547 39 0.082
cardiovascular system development GO:0072358 82 0.081
larval midgut histolysis GO:0035069 22 0.081
epithelial tube morphogenesis GO:0060562 88 0.080
regulation of neuron differentiation GO:0045664 103 0.079
positive regulation of cell proliferation GO:0008284 47 0.079
photoreceptor cell development GO:0042461 96 0.079
regulation of gene expression epigenetic GO:0040029 128 0.079
regulation of protein phosphorylation GO:0001932 64 0.079
Human
embryonic organ development GO:0048568 50 0.078
regulation of rac protein signal transduction GO:0035020 3 0.078
purine nucleoside triphosphate catabolic process GO:0009146 108 0.078
secretion by cell GO:0032940 101 0.078
glycosyl compound metabolic process GO:1901657 127 0.077
protein complex assembly GO:0006461 200 0.076
Human
imaginal disc derived leg morphogenesis GO:0007480 80 0.076
positive regulation of developmental process GO:0051094 143 0.076
regulation of protein kinase activity GO:0045859 51 0.075
Human
regulation of neural precursor cell proliferation GO:2000177 35 0.075
single organism intracellular transport GO:1902582 207 0.075
response to glucose GO:0009749 2 0.075
response to light stimulus GO:0009416 124 0.075
cell division GO:0051301 248 0.074
positive regulation of cellular catabolic process GO:0031331 95 0.074
protein processing GO:0016485 68 0.074
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.074
spermatid differentiation GO:0048515 114 0.073
cardiocyte differentiation GO:0035051 29 0.073
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.073
regulation of actin polymerization or depolymerization GO:0008064 27 0.072
Human
regulation of cellular component biogenesis GO:0044087 201 0.072
Human
regulation of macroautophagy GO:0016241 15 0.072
protein acetylation GO:0006473 39 0.071
purine nucleotide catabolic process GO:0006195 109 0.071
negative regulation of epithelial cell proliferation GO:0050680 4 0.071
vesicle mediated transport GO:0016192 381 0.071
regulation of cellular amine metabolic process GO:0033238 3 0.070
nucleoside catabolic process GO:0009164 112 0.069
chemotaxis GO:0006935 249 0.069
positive regulation of cell communication GO:0010647 250 0.069
nucleoside phosphate catabolic process GO:1901292 110 0.069
mesenchymal cell development GO:0014031 1 0.068
learning or memory GO:0007611 141 0.068
ribonucleoside triphosphate metabolic process GO:0009199 119 0.068
regulation of tube length open tracheal system GO:0035159 24 0.068
tissue migration GO:0090130 155 0.068
establishment of protein localization GO:0045184 163 0.067
Human
regulation of hydrolase activity GO:0051336 97 0.067
regulation of establishment of protein localization GO:0070201 61 0.066
Human
regulation of cellular protein metabolic process GO:0032268 243 0.066
Human
negative regulation of apoptotic process GO:0043066 63 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.066
protein ubiquitination GO:0016567 70 0.064
activation of cysteine type endopeptidase activity GO:0097202 17 0.063
proteasomal protein catabolic process GO:0010498 59 0.063
heart development GO:0007507 82 0.062
secretion GO:0046903 109 0.062
ribonucleoside metabolic process GO:0009119 127 0.062
axon guidance GO:0007411 233 0.061
positive regulation of stem cell proliferation GO:2000648 8 0.061
positive regulation of cellular component biogenesis GO:0044089 80 0.061
negative regulation of developmental process GO:0051093 201 0.061
purine containing compound catabolic process GO:0072523 112 0.061
regulation of gliogenesis GO:0014013 11 0.060
positive regulation of growth GO:0045927 75 0.060
ribonucleotide metabolic process GO:0009259 145 0.060
negative regulation of cellular component organization GO:0051129 108 0.059
neuron maturation GO:0042551 31 0.059
apoptotic signaling pathway GO:0097190 27 0.059
purine ribonucleoside metabolic process GO:0046128 127 0.059
negative regulation of multicellular organismal process GO:0051241 142 0.058
mesenchymal cell differentiation GO:0048762 1 0.058
organophosphate metabolic process GO:0019637 195 0.057
protein import GO:0017038 55 0.057
developmental growth involved in morphogenesis GO:0060560 65 0.057
regulation of anatomical structure size GO:0090066 163 0.057
Human
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.057
long term memory GO:0007616 62 0.057
cell cycle phase transition GO:0044770 140 0.057
equator specification GO:0045317 4 0.057
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.057
organic substance catabolic process GO:1901575 308 0.057
regulation of catabolic process GO:0009894 170 0.056
covalent chromatin modification GO:0016569 106 0.056
morphogenesis of a branching structure GO:0001763 45 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
response to monosaccharide GO:0034284 4 0.056
positive regulation of rna metabolic process GO:0051254 271 0.055
chaeta development GO:0022416 97 0.055
positive regulation of phosphorylation GO:0042327 87 0.055
Human
camera type eye development GO:0043010 4 0.054
purine nucleotide metabolic process GO:0006163 146 0.054
purine ribonucleoside catabolic process GO:0046130 112 0.054
protein import into nucleus GO:0006606 51 0.054
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.054
zymogen activation GO:0031638 20 0.052
gastrulation GO:0007369 70 0.051
positive regulation of rna biosynthetic process GO:1902680 266 0.051
cell maturation GO:0048469 144 0.051
negative regulation of catalytic activity GO:0043086 42 0.051
Human
ameboidal type cell migration GO:0001667 151 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.051
response to organonitrogen compound GO:0010243 75 0.050
regulation of kinase activity GO:0043549 53 0.050
Human
morphogenesis of a branching epithelium GO:0061138 45 0.050
defense response GO:0006952 300 0.049
chromosome organization GO:0051276 360 0.049
Human
oocyte microtubule cytoskeleton organization GO:0016325 35 0.049
tissue death GO:0016271 102 0.049
nuclear import GO:0051170 51 0.049
r8 cell fate commitment GO:0007460 6 0.048
heart morphogenesis GO:0003007 32 0.048
cellular response to abiotic stimulus GO:0071214 58 0.048
regulation of autophagy GO:0010506 62 0.048
rac protein signal transduction GO:0016601 3 0.048
neural precursor cell proliferation GO:0061351 75 0.047
organophosphate catabolic process GO:0046434 112 0.047
regulation of cellular response to stress GO:0080135 89 0.047
actin filament bundle assembly GO:0051017 26 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.047
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
renal tubule development GO:0061326 64 0.046
nephron development GO:0072006 3 0.046
skin development GO:0043588 65 0.046
Mouse
regulation of neuroblast proliferation GO:1902692 34 0.046
positive regulation of response to stimulus GO:0048584 323 0.046
negative regulation of cell cycle process GO:0010948 109 0.045
positive regulation of cytoskeleton organization GO:0051495 21 0.045
chemical homeostasis GO:0048878 92 0.045
signal transduction by phosphorylation GO:0023014 107 0.044
chromatin organization GO:0006325 207 0.044
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.044
glial cell migration GO:0008347 31 0.044
ribose phosphate metabolic process GO:0019693 145 0.044
single organism catabolic process GO:0044712 228 0.044
hindbrain development GO:0030902 2 0.044
cellular response to extracellular stimulus GO:0031668 64 0.044
imaginal disc derived appendage morphogenesis GO:0035114 395 0.044
carbohydrate derivative catabolic process GO:1901136 118 0.044
regulation of photoreceptor cell differentiation GO:0046532 34 0.044
negative regulation of neurogenesis GO:0050768 53 0.043
r3 r4 cell fate commitment GO:0007464 10 0.043
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.043
cell recognition GO:0008037 102 0.042
negative regulation of developmental growth GO:0048640 64 0.042
embryonic morphogenesis GO:0048598 206 0.042
positive regulation of phosphorus metabolic process GO:0010562 139 0.042
Human
response to hypoxia GO:0001666 53 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
positive regulation of kinase activity GO:0033674 25 0.041
regulation of protein polymerization GO:0032271 28 0.041
Human
protein acylation GO:0043543 42 0.041
epithelial cell proliferation GO:0050673 15 0.041
actin filament bundle organization GO:0061572 28 0.040
protein localization to nucleus GO:0034504 55 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.040
response to hormone GO:0009725 45 0.040
Human Mouse
regulation of tor signaling GO:0032006 21 0.039
negative regulation of hippo signaling GO:0035331 5 0.039
convergent extension GO:0060026 2 0.039
phagocytosis GO:0006909 215 0.038
organonitrogen compound metabolic process GO:1901564 318 0.038
modification dependent protein catabolic process GO:0019941 78 0.037
regulation of ras protein signal transduction GO:0046578 93 0.037
regulation of synapse structure and activity GO:0050803 128 0.037
single organism behavior GO:0044708 391 0.037
autophagic vacuole assembly GO:0000045 2 0.036
camera type eye morphogenesis GO:0048593 2 0.036
gland development GO:0048732 191 0.036
nucleotide catabolic process GO:0009166 109 0.036
smoothened signaling pathway GO:0007224 49 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
regulation of defense response GO:0031347 102 0.035
cellular macromolecule localization GO:0070727 220 0.035
Human Mouse
peptidyl tyrosine phosphorylation GO:0018108 24 0.035
response to nitrogen compound GO:1901698 90 0.035
negative regulation of immune response GO:0050777 39 0.035
positive regulation of r7 cell differentiation GO:0045678 7 0.035
response to transforming growth factor beta GO:0071559 18 0.035
regulation of response to extracellular stimulus GO:0032104 18 0.035
positive regulation of catabolic process GO:0009896 105 0.034
establishment of planar polarity GO:0001736 87 0.034
nucleotide metabolic process GO:0009117 161 0.034
stem cell proliferation GO:0072089 88 0.034
glycosyl compound catabolic process GO:1901658 112 0.034
positive regulation of organ growth GO:0046622 12 0.034
positive regulation of transport GO:0051050 92 0.034
regulation of actin filament polymerization GO:0030833 25 0.034
Human
regulation of establishment of planar polarity GO:0090175 22 0.034
regulation of neuron projection development GO:0010975 69 0.034
muscle structure development GO:0061061 224 0.034
regulation of ras gtpase activity GO:0032318 38 0.033
eggshell chorion assembly GO:0007306 66 0.033
establishment of protein localization to organelle GO:0072594 62 0.033
regulation of endocytosis GO:0030100 37 0.033
spermatogenesis GO:0007283 200 0.033
gtp catabolic process GO:0006184 72 0.033
positive regulation of cell development GO:0010720 61 0.033
regulation of nucleocytoplasmic transport GO:0046822 35 0.033
neuron apoptotic process GO:0051402 17 0.033
developmental programmed cell death GO:0010623 138 0.032
epithelial cell migration GO:0010631 148 0.032
positive regulation of biosynthetic process GO:0009891 316 0.032
response to organic cyclic compound GO:0014070 89 0.032
negative regulation of nervous system development GO:0051961 92 0.032
regulation of immune system process GO:0002682 176 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
chorion containing eggshell formation GO:0007304 105 0.032
protein targeting to nucleus GO:0044744 51 0.032
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.032
positive regulation of mapk cascade GO:0043410 63 0.031
limb morphogenesis GO:0035108 1 0.031
endocytosis GO:0006897 310 0.031
regulation of response to stress GO:0080134 200 0.031
tor signaling GO:0031929 32 0.030
positive regulation of organelle organization GO:0010638 65 0.030
protein localization to organelle GO:0033365 82 0.030
ribonucleoside catabolic process GO:0042454 112 0.030
nucleoside metabolic process GO:0009116 127 0.030
asymmetric protein localization GO:0008105 33 0.030
Worm
muscle organ development GO:0007517 127 0.029
purine nucleoside catabolic process GO:0006152 112 0.029
regulation of small gtpase mediated signal transduction GO:0051056 93 0.029
membrane organization GO:0061024 112 0.029
cell cycle g1 s phase transition GO:0044843 31 0.029
vesicle organization GO:0016050 44 0.029
development of primary female sexual characteristics GO:0046545 12 0.028
renal tubule morphogenesis GO:0061333 44 0.028
purine containing compound metabolic process GO:0072521 155 0.028
positive regulation of developmental growth GO:0048639 62 0.028

wts disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.108
disease of anatomical entity DOID:7 0 0.077
cancer DOID:162 0 0.068
organ system cancer DOID:0050686 0 0.068
nervous system disease DOID:863 0 0.056
disease of metabolism DOID:0014667 0 0.041
cardiovascular system disease DOID:1287 0 0.034