Drosophila melanogaster

125 known processes

hiw (Dmel_CG32592)

highwire

(Aliases: CG9041,Hiw,CG32592,CG9049,Dmel\CG32592)

hiw biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 1.000
synaptic vesicle transport GO:0048489 50 0.997
synapse organization GO:0050808 196 0.997
synaptic vesicle recycling GO:0036465 28 0.995
synaptic vesicle exocytosis GO:0016079 16 0.987
regulation of synaptic transmission GO:0050804 69 0.987
establishment of vesicle localization GO:0051650 51 0.987
axon development GO:0061564 297 0.985
Zebrafish Mouse
establishment of synaptic vesicle localization GO:0097480 50 0.979
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.944
axonogenesis GO:0007409 290 0.939
Zebrafish Mouse
regulation of synapse structure and activity GO:0050803 128 0.922
neuromuscular synaptic transmission GO:0007274 67 0.908
synaptic vesicle endocytosis GO:0048488 28 0.907
regulation of synapse organization GO:0050807 110 0.905
neurotransmitter secretion GO:0007269 35 0.893
establishment of localization in cell GO:0051649 402 0.848
neurotransmitter transport GO:0006836 37 0.836
vesicle localization GO:0051648 55 0.793
neuromuscular junction development GO:0007528 149 0.773
regulation of neurotransmitter levels GO:0001505 38 0.771
regulation of vesicle mediated transport GO:0060627 59 0.745
positive regulation of synaptic vesicle recycling GO:1903423 4 0.720
establishment of organelle localization GO:0051656 122 0.707
synaptic vesicle localization GO:0097479 53 0.707
neuron neuron synaptic transmission GO:0007270 14 0.686
neuron maturation GO:0042551 31 0.676
synapse assembly GO:0007416 143 0.649
rhythmic excitation GO:0043179 1 0.647
synaptic transmission glutamatergic GO:0035249 7 0.641
regulation of neurogenesis GO:0050767 158 0.629
signal release GO:0023061 49 0.626
developmental maturation GO:0021700 172 0.611
regulation of neurotransmitter secretion GO:0046928 14 0.604
maintenance of presynaptic active zone structure GO:0048790 8 0.568
secretion by cell GO:0032940 101 0.564
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.546
cell death GO:0008219 279 0.540
Worm
positive regulation of cellular component organization GO:0051130 156 0.521
regulation of terminal button organization GO:2000331 11 0.518
organelle localization GO:0051640 148 0.517
regulation of synapse assembly GO:0051963 94 0.507
regulation of cell development GO:0060284 215 0.495
vesicle mediated transport GO:0016192 381 0.474
regulation of multicellular organismal development GO:2000026 414 0.460
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.459
cell maturation GO:0048469 144 0.454
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.451
growth GO:0040007 359 0.451
regulation of cell differentiation GO:0045595 302 0.437
dendrite development GO:0016358 204 0.427
single organism membrane fusion GO:0044801 42 0.427
developmental growth involved in morphogenesis GO:0060560 65 0.426
terminal button organization GO:0072553 19 0.409
regulation of neuromuscular synaptic transmission GO:1900073 15 0.405
regulation of nervous system development GO:0051960 248 0.397
regulation of synaptic vesicle endocytosis GO:1900242 7 0.389
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.346
learning GO:0007612 75 0.341
locomotory behavior GO:0007626 176 0.334
regulation of cellular component biogenesis GO:0044087 201 0.332
positive regulation of cell development GO:0010720 61 0.318
synaptic growth at neuromuscular junction GO:0051124 119 0.316
regulation of neuron differentiation GO:0045664 103 0.312
developmental growth GO:0048589 280 0.301
vesicle organization GO:0016050 44 0.301
regulation of synaptic transmission glutamatergic GO:0051966 5 0.299
positive regulation of neurogenesis GO:0050769 41 0.298
positive regulation of synaptic transmission GO:0050806 15 0.291
regulation of secretion GO:0051046 44 0.275
membrane organization GO:0061024 112 0.274
regulation of localization GO:0032879 275 0.274
Mouse
death GO:0016265 284 0.250
Worm
positive regulation of developmental process GO:0051094 143 0.243
positive regulation of nervous system development GO:0051962 69 0.241
regulation of membrane potential GO:0042391 35 0.238
membrane fusion GO:0061025 42 0.233
regulation of anatomical structure size GO:0090066 163 0.231
secretion GO:0046903 109 0.226
protein complex assembly GO:0006461 200 0.225
regulation of secretion by cell GO:1903530 39 0.225
adult locomotory behavior GO:0008344 76 0.221
positive regulation of synapse assembly GO:0051965 29 0.212
positive regulation of neuron differentiation GO:0045666 26 0.201
negative regulation of cellular component organization GO:0051129 108 0.199
protein localization GO:0008104 284 0.198
Mouse
positive regulation of axon guidance GO:1902669 1 0.193
dendrite morphogenesis GO:0048813 199 0.188
positive regulation of signaling GO:0023056 243 0.185
regulation of neuron projection development GO:0010975 69 0.179
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.178
negative regulation of gene expression GO:0010629 387 0.175
negative regulation of synapse assembly GO:0051964 39 0.169
axon guidance GO:0007411 233 0.166
Zebrafish Mouse
proteolysis GO:0006508 192 0.164
developmental cell growth GO:0048588 52 0.163
organelle fusion GO:0048284 46 0.162
regulation of endocytosis GO:0030100 37 0.162
positive regulation of multicellular organismal process GO:0051240 143 0.156
cognition GO:0050890 141 0.149
regulation of transmembrane transport GO:0034762 27 0.147
lipid modification GO:0030258 24 0.145
central nervous system development GO:0007417 201 0.144
Zebrafish Mouse
head development GO:0060322 135 0.143
Zebrafish
receptor clustering GO:0043113 3 0.140
multicellular organism growth GO:0035264 46 0.140
positive regulation of cell differentiation GO:0045597 64 0.139
positive regulation of cell communication GO:0010647 250 0.139
endocytosis GO:0006897 310 0.136
regulation of cell projection organization GO:0031344 92 0.133
regulation of dendrite morphogenesis GO:0048814 28 0.131
exocytosis GO:0006887 28 0.127
response to hydrogen peroxide GO:0042542 11 0.123
brain development GO:0007420 120 0.123
Zebrafish
regulation of necrotic cell death GO:0010939 1 0.120
neuromuscular process GO:0050905 21 0.114
positive regulation of transport GO:0051050 92 0.111
endomembrane system organization GO:0010256 119 0.109
positive regulation of cell death GO:0010942 69 0.107
regulation of neurotransmitter transport GO:0051588 14 0.106
cell growth GO:0016049 108 0.105
cortical cytoskeleton organization GO:0030865 29 0.104
regulation of receptor mediated endocytosis GO:0048259 9 0.104
positive regulation of biosynthetic process GO:0009891 316 0.103
ribonucleotide metabolic process GO:0009259 145 0.101
single organism behavior GO:0044708 391 0.101
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.100
single organism membrane organization GO:0044802 93 0.099
regulation of synaptic vesicle transport GO:1902803 10 0.098
catabolic process GO:0009056 409 0.098
intraspecies interaction between organisms GO:0051703 4 0.097
cell cell adhesion GO:0098609 26 0.096
positive regulation of dendrite morphogenesis GO:0050775 9 0.095
feeding behavior GO:0007631 50 0.093
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.091
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.091
protein heterooligomerization GO:0051291 4 0.090
regulation of cellular localization GO:0060341 136 0.087
protein complex biogenesis GO:0070271 201 0.087
purine ribonucleotide metabolic process GO:0009150 145 0.085
regulation of synaptic vesicle recycling GO:1903421 7 0.083
membrane depolarization GO:0051899 4 0.083
regulation of cell death GO:0010941 173 0.081
axon midline choice point recognition GO:0016199 26 0.077
neuron projection guidance GO:0097485 241 0.075
Zebrafish Mouse
rhythmic synaptic transmission GO:0060024 2 0.074
cellular protein modification process GO:0006464 438 0.074
Zebrafish Worm
positive regulation of exocytosis GO:0045921 4 0.073
single organism intracellular transport GO:1902582 207 0.072
neurological system process GO:0050877 358 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
regulation of system process GO:0044057 36 0.068
regulation of organelle organization GO:0033043 196 0.068
Mouse
neuron remodeling GO:0016322 29 0.067
kidney development GO:0001822 3 0.066
positive regulation of axonogenesis GO:0050772 2 0.065
synapse maturation GO:0060074 7 0.065
intracellular transport GO:0046907 228 0.065
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.064
forebrain development GO:0030900 2 0.064
Zebrafish
gliogenesis GO:0042063 80 0.064
transmembrane transport GO:0055085 139 0.064
anterograde synaptic vesicle transport GO:0048490 3 0.063
axon extension GO:0048675 32 0.063
regulation of gene expression epigenetic GO:0040029 128 0.062
nucleobase containing small molecule metabolic process GO:0055086 174 0.061
response to organic substance GO:0010033 284 0.061
negative regulation of cellular biosynthetic process GO:0031327 277 0.060
positive regulation of neurotransmitter secretion GO:0001956 2 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.058
modification dependent protein catabolic process GO:0019941 78 0.056
intracellular signal transduction GO:0035556 300 0.056
Worm
positive regulation of secretion by cell GO:1903532 20 0.056
response to radiation GO:0009314 155 0.055
regulation of intracellular signal transduction GO:1902531 236 0.054
Worm
protein phosphorylation GO:0006468 169 0.054
spinal cord development GO:0021510 1 0.051
synaptic vesicle priming GO:0016082 1 0.051
autophagy GO:0006914 108 0.051
regulation of synaptic vesicle exocytosis GO:2000300 3 0.051
neuron projection extension GO:1990138 32 0.051
associative learning GO:0008306 65 0.050
organonitrogen compound metabolic process GO:1901564 318 0.050
Zebrafish
single organism catabolic process GO:0044712 228 0.050
regulation of transport GO:0051049 181 0.049
macromolecular complex assembly GO:0065003 256 0.049
axon choice point recognition GO:0016198 26 0.048
Zebrafish
regulation of dendrite development GO:0050773 37 0.048
nucleoside catabolic process GO:0009164 112 0.047
telencephalon development GO:0021537 2 0.047
protein modification by small protein conjugation or removal GO:0070647 106 0.047
Zebrafish Worm
nucleoside triphosphate metabolic process GO:0009141 120 0.047
regulation of ion transmembrane transport GO:0034765 27 0.047
conditioned taste aversion GO:0001661 3 0.046
muscle contraction GO:0006936 13 0.046
hindbrain development GO:0030902 2 0.046
mating GO:0007618 120 0.046
positive regulation of neuron projection development GO:0010976 14 0.045
positive regulation of catalytic activity GO:0043085 118 0.045
lipid homeostasis GO:0055088 33 0.045
response to organic cyclic compound GO:0014070 89 0.045
organonitrogen compound catabolic process GO:1901565 128 0.043
filopodium assembly GO:0046847 33 0.042
ribonucleoside metabolic process GO:0009119 127 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
organophosphate metabolic process GO:0019637 195 0.041
small molecule metabolic process GO:0044281 305 0.041
neuron cell cell adhesion GO:0007158 1 0.041
protein catabolic process GO:0030163 101 0.041
Mouse
neuroblast proliferation GO:0007405 74 0.040
cellular protein complex disassembly GO:0043624 35 0.040
microtubule based transport GO:0010970 42 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.039
learning or memory GO:0007611 141 0.039
cellular protein complex assembly GO:0043623 71 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
negative regulation of nervous system development GO:0051961 92 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.037
organic cyclic compound catabolic process GO:1901361 168 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.037
Worm
negative regulation of biosynthetic process GO:0009890 277 0.037
regulation of neuroblast proliferation GO:1902692 34 0.036
ubiquitin dependent protein catabolic process GO:0006511 78 0.036
positive regulation of cell projection organization GO:0031346 29 0.036
regionalization GO:0003002 416 0.036
cellular amide metabolic process GO:0043603 80 0.036
negative regulation of growth GO:0045926 84 0.035
nucleobase containing compound catabolic process GO:0034655 165 0.035
embryonic pattern specification GO:0009880 174 0.035
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.035
protein kinase a signaling GO:0010737 2 0.034
cytoskeletal matrix organization at active zone GO:0048789 5 0.034
membrane budding GO:0006900 4 0.034
positive regulation of developmental growth GO:0048639 62 0.034
purine containing compound catabolic process GO:0072523 112 0.034
meiotic nuclear division GO:0007126 151 0.034
ion transmembrane transport GO:0034220 122 0.033
response to starvation GO:0042594 97 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.033
positive regulation of endocytosis GO:0045807 22 0.033
positive regulation of cellular component biogenesis GO:0044089 80 0.032
regulation of response to external stimulus GO:0032101 115 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
membrane biogenesis GO:0044091 8 0.032
oocyte development GO:0048599 124 0.032
nucleoside phosphate catabolic process GO:1901292 110 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
protein depolymerization GO:0051261 31 0.031
eye antennal disc development GO:0035214 60 0.031
gtp catabolic process GO:0006184 72 0.031
oocyte anterior posterior axis specification GO:0007314 72 0.030
vesicle fusion GO:0006906 19 0.030
purine nucleoside catabolic process GO:0006152 112 0.030
purine containing compound metabolic process GO:0072521 155 0.030
protein modification by small protein conjugation GO:0032446 79 0.030
Zebrafish Worm
regulation of cell projection assembly GO:0060491 30 0.030
sensory organ morphogenesis GO:0090596 260 0.029
response to external biotic stimulus GO:0043207 293 0.029
male courtship behavior veined wing vibration GO:0016545 21 0.029
regulation of bmp signaling pathway GO:0030510 23 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
purine nucleotide catabolic process GO:0006195 109 0.029
positive regulation of neuromuscular synaptic transmission GO:1900075 4 0.028
positive regulation of rna metabolic process GO:0051254 271 0.028
segmentation GO:0035282 207 0.028
isoprenoid transport GO:0046864 2 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
protein ubiquitination GO:0016567 70 0.028
Zebrafish Worm
organic hydroxy compound metabolic process GO:1901615 83 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
ribonucleotide catabolic process GO:0009261 109 0.027
notch signaling pathway GO:0007219 120 0.027
determination of dorsal ventral asymmetry GO:0048262 3 0.026
regulation of phosphatase activity GO:0010921 3 0.026
regulation of molecular function GO:0065009 217 0.026
ion transport GO:0006811 145 0.026
ovarian follicle cell development GO:0030707 248 0.026
protein complex disassembly GO:0043241 36 0.026
organelle fission GO:0048285 340 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
homeostatic process GO:0042592 199 0.025
regulation of growth GO:0040008 233 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
regulation of ion transmembrane transporter activity GO:0032412 6 0.024
regulation of neuronal synaptic plasticity GO:0048168 8 0.024
ribonucleoside catabolic process GO:0042454 112 0.024
regulation of exocytosis GO:0017157 6 0.024
positive regulation of neurotransmitter transport GO:0051590 2 0.024
positive regulation of signal transduction GO:0009967 223 0.024
nucleoside metabolic process GO:0009116 127 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
receptor mediated endocytosis GO:0006898 21 0.024
detection of light stimulus GO:0009583 58 0.024
detection of chemical stimulus GO:0009593 93 0.023
epithelial cell development GO:0002064 274 0.023
regulation of multi organism process GO:0043900 131 0.023
regulation of glial cell differentiation GO:0045685 1 0.023
glial cell differentiation GO:0010001 35 0.023
regulation of pole plasm oskar mrna localization GO:0007317 27 0.023
muscle system process GO:0003012 21 0.023
regulation of rac protein signal transduction GO:0035020 3 0.023
protein oligomerization GO:0051259 16 0.023
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.022
organic substance transport GO:0071702 257 0.022
blood circulation GO:0008015 26 0.022
limb morphogenesis GO:0035108 1 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
regulation of proteolysis GO:0030162 87 0.022
necrotic cell death GO:0070265 1 0.022
positive regulation of secretion GO:0051047 22 0.022
cellular macromolecule localization GO:0070727 220 0.021
anterior posterior pattern specification GO:0009952 136 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
mapk cascade GO:0000165 107 0.021
Worm
neurotransmitter gated ion channel clustering GO:0072578 2 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 1 0.021
regulation of hydrolase activity GO:0051336 97 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
negative regulation of developmental growth GO:0048640 64 0.020
regulation of glutamate receptor signaling pathway GO:1900449 1 0.020
single organismal cell cell adhesion GO:0016337 45 0.020
response to oxidative stress GO:0006979 86 0.020
cellular component assembly involved in morphogenesis GO:0010927 151 0.020
cellular response to extracellular stimulus GO:0031668 64 0.020
sensory perception of smell GO:0007608 80 0.020
macromolecular complex disassembly GO:0032984 37 0.020
axon cargo transport GO:0008088 29 0.019
regulation of cell size GO:0008361 63 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
cell recognition GO:0008037 102 0.019
Zebrafish
regulation of developmental growth GO:0048638 174 0.019
cation transport GO:0006812 110 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
Worm
cellular catabolic process GO:0044248 372 0.019
cellular response to organic substance GO:0071310 132 0.018
negative regulation of organelle organization GO:0010639 56 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
positive regulation of cell cycle process GO:0090068 28 0.018
phenol containing compound metabolic process GO:0018958 57 0.018
mating behavior sex discrimination GO:0048047 7 0.018
regulation of catabolic process GO:0009894 170 0.018
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.018
regulation of programmed cell death GO:0043067 152 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.018
positive regulation of organelle organization GO:0010638 65 0.017
intracellular protein transport GO:0006886 104 0.017
compound eye development GO:0048749 307 0.017
response to abiotic stimulus GO:0009628 341 0.017
cellular response to external stimulus GO:0071496 66 0.017
cell migration GO:0016477 238 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
negative regulation of protein complex disassembly GO:0043242 23 0.017
positive regulation of gene expression GO:0010628 290 0.017
nucleotide catabolic process GO:0009166 109 0.017
single organism cell adhesion GO:0098602 47 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
Mouse
positive regulation of molecular function GO:0044093 136 0.017
collateral sprouting GO:0048668 3 0.017
meiotic cell cycle GO:0051321 171 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
regulation of actin filament based process GO:0032970 42 0.016
protein maturation GO:0051604 71 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
synaptic transmission gabaergic GO:0051932 1 0.016
neurotransmitter receptor metabolic process GO:0045213 3 0.016
female meiotic division GO:0007143 70 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
programmed cell death GO:0012501 257 0.016
Worm
regulation of cellular protein metabolic process GO:0032268 243 0.016
adult behavior GO:0030534 137 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
epithelial cell differentiation GO:0030855 322 0.016
male gamete generation GO:0048232 201 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
organic substance catabolic process GO:1901575 308 0.016
Mouse
male courtship behavior veined wing generated song production GO:0045433 20 0.016
cellular response to starvation GO:0009267 61 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
regulation of receptor activity GO:0010469 10 0.016
peripheral nervous system development GO:0007422 52 0.016
golgi vesicle transport GO:0048193 27 0.016
cytoplasmic transport GO:0016482 130 0.016
establishment of mitochondrion localization GO:0051654 7 0.016
cellular macromolecular complex assembly GO:0034622 153 0.015
cardiac cell fate specification GO:0060912 10 0.015
cellular lipid metabolic process GO:0044255 83 0.015
carbohydrate metabolic process GO:0005975 82 0.015
inorganic cation transmembrane transport GO:0098662 61 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
negative regulation of cellular response to oxidative stress GO:1900408 1 0.015
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.015
presynaptic membrane organization GO:0097090 4 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
membrane tubulation GO:0097320 4 0.015
cellular response to hexose stimulus GO:0071331 1 0.015
response to heat GO:0009408 63 0.014
cellular component maintenance GO:0043954 23 0.014
positive regulation of receptor mediated endocytosis GO:0048260 7 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
heterochromatin organization GO:0070828 25 0.014
gene silencing by mirna GO:0035195 22 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
negative regulation of developmental process GO:0051093 201 0.014
regulation of transporter activity GO:0032409 6 0.014
chromosome segregation GO:0007059 157 0.014
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
nuclear division GO:0000280 332 0.014
mushroom body development GO:0016319 70 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
central nervous system neuron axonogenesis GO:0021955 7 0.014
Mouse
cellular component disassembly GO:0022411 46 0.014
cellular protein localization GO:0034613 160 0.014
regulation of cell cycle process GO:0010564 181 0.014
positive regulation of programmed cell death GO:0043068 62 0.013
regulation of steroid metabolic process GO:0019218 2 0.013
response to ketone GO:1901654 34 0.013
neuroblast differentiation GO:0014016 29 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
organophosphate catabolic process GO:0046434 112 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
Worm
positive regulation of phosphorylation GO:0042327 87 0.013
mitotic nuclear division GO:0007067 213 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
compound eye morphogenesis GO:0001745 249 0.013
oocyte fate determination GO:0030716 27 0.013
germline stem cell asymmetric division GO:0098728 15 0.013
cellular response to nutrient levels GO:0031669 62 0.013
eye development GO:0001654 323 0.013
positive regulation of multicellular organism growth GO:0040018 21 0.013
neuron recognition GO:0008038 101 0.013
Zebrafish
protein transport GO:0015031 155 0.013
regulation of neuron death GO:1901214 26 0.013
response to monosaccharide GO:0034284 4 0.012
carbohydrate homeostasis GO:0033500 12 0.012
regulation of cell maturation GO:1903429 27 0.012
regulation of embryonic pattern specification GO:1902875 27 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
response to alkaloid GO:0043279 26 0.012
wnt signaling pathway GO:0016055 98 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
central nervous system neuron differentiation GO:0021953 8 0.012
Mouse
nucleotide metabolic process GO:0009117 161 0.012
autophagic vacuole assembly GO:0000045 2 0.012
blastoderm segmentation GO:0007350 159 0.012
actin cytoskeleton organization GO:0030036 206 0.012
collateral sprouting of injured axon GO:0048674 3 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
jak stat cascade GO:0007259 49 0.011
regulation of axon extension involved in axon guidance GO:0048841 4 0.011
regulation of axonogenesis GO:0050770 32 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
negative regulation of cell communication GO:0010648 223 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
vitamin transport GO:0051180 2 0.011
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.011
humoral immune response GO:0006959 117 0.011
response to reactive oxygen species GO:0000302 24 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.011
dendrite guidance GO:0070983 21 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
positive regulation of axon extension GO:0045773 2 0.011
anterior posterior axis specification GO:0009948 109 0.011
negative regulation of protein processing GO:0010955 31 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
lipid localization GO:0010876 54 0.011

hiw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.168
central nervous system disease DOID:331 0 0.030
neurodegenerative disease DOID:1289 0 0.030
nervous system disease DOID:863 0 0.030
cardiovascular system disease DOID:1287 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
neuromuscular disease DOID:440 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuropathy DOID:870 0 0.012
synucleinopathy DOID:0050890 0 0.011