Drosophila melanogaster

25 known processes

Flo-2 (Dmel_CG32593)

flotillin 2

(Aliases: DmFlo2,FLO2,CG32593,CG11547,reggie1/flo2,flo2,FLO[Dm]-2,Dmel\CG32593,CG14409)

Flo-2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
melanotic encapsulation of foreign target GO:0035011 30 0.983
encapsulation of foreign target GO:0035010 38 0.977
melanin metabolic process GO:0006582 47 0.936
pigment metabolic process GO:0042440 84 0.931
melanization defense response GO:0035006 45 0.930
secondary metabolic process GO:0019748 75 0.879
phenol containing compound metabolic process GO:0018958 57 0.870
immune effector process GO:0002252 98 0.717
innate immune response GO:0045087 144 0.674
organic hydroxy compound metabolic process GO:1901615 83 0.634
immune system process GO:0002376 347 0.427
immune response GO:0006955 246 0.192
gtp catabolic process GO:0006184 72 0.174
purine nucleoside triphosphate catabolic process GO:0009146 108 0.173
gtp metabolic process GO:0046039 72 0.159
taxis GO:0042330 304 0.154
ribonucleotide metabolic process GO:0009259 145 0.153
organophosphate metabolic process GO:0019637 195 0.152
guanosine containing compound metabolic process GO:1901068 74 0.151
ribose phosphate metabolic process GO:0019693 145 0.151
small molecule metabolic process GO:0044281 305 0.140
regulation of cellular catabolic process GO:0031329 157 0.138
cellular protein modification process GO:0006464 438 0.135
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.133
carbohydrate derivative metabolic process GO:1901135 217 0.131
organonitrogen compound metabolic process GO:1901564 318 0.129
imaginal disc derived leg morphogenesis GO:0007480 80 0.128
neuron projection guidance GO:0097485 241 0.127
ribonucleoside metabolic process GO:0009119 127 0.126
ras protein signal transduction GO:0007265 88 0.126
imaginal disc derived appendage morphogenesis GO:0035114 395 0.120
regulation of catabolic process GO:0009894 170 0.119
purine nucleotide metabolic process GO:0006163 146 0.118
vesicle mediated transport GO:0016192 381 0.116
nucleoside catabolic process GO:0009164 112 0.109
nucleoside metabolic process GO:0009116 127 0.108
leg disc development GO:0035218 92 0.108
nucleoside triphosphate catabolic process GO:0009143 108 0.107
aromatic compound catabolic process GO:0019439 166 0.107
axon guidance GO:0007411 233 0.106
regulation of cellular component biogenesis GO:0044087 201 0.105
nucleobase containing small molecule metabolic process GO:0055086 174 0.104
imaginal disc derived appendage development GO:0048737 399 0.104
ribonucleoside triphosphate catabolic process GO:0009203 108 0.104
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.104
glycosyl compound metabolic process GO:1901657 127 0.101
purine ribonucleoside catabolic process GO:0046130 112 0.101
catabolic process GO:0009056 409 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.100
purine containing compound catabolic process GO:0072523 112 0.098
glycosyl compound catabolic process GO:1901658 112 0.097
organophosphate catabolic process GO:0046434 112 0.097
appendage development GO:0048736 401 0.092
post embryonic appendage morphogenesis GO:0035120 385 0.091
single organism catabolic process GO:0044712 228 0.089
purine nucleoside catabolic process GO:0006152 112 0.088
purine containing compound metabolic process GO:0072521 155 0.087
cellular catabolic process GO:0044248 372 0.087
regulation of nucleoside metabolic process GO:0009118 50 0.086
respiratory system development GO:0060541 213 0.086
cellular nitrogen compound catabolic process GO:0044270 165 0.085
sensory organ morphogenesis GO:0090596 260 0.085
small gtpase mediated signal transduction GO:0007264 88 0.083
purine ribonucleotide metabolic process GO:0009150 145 0.083
organonitrogen compound catabolic process GO:1901565 128 0.083
purine nucleotide catabolic process GO:0006195 109 0.082
endocytosis GO:0006897 310 0.081
nucleotide catabolic process GO:0009166 109 0.081
positive regulation of response to stimulus GO:0048584 323 0.080
organic cyclic compound catabolic process GO:1901361 168 0.079
nucleotide metabolic process GO:0009117 161 0.077
body morphogenesis GO:0010171 2 0.077
nucleoside phosphate metabolic process GO:0006753 162 0.075
guanosine containing compound catabolic process GO:1901069 74 0.072
neurological system process GO:0050877 358 0.072
regulation of molecular function GO:0065009 217 0.071
single organism behavior GO:0044708 391 0.071
defense response GO:0006952 300 0.070
carbohydrate derivative catabolic process GO:1901136 118 0.070
single organism biosynthetic process GO:0044711 206 0.070
positive regulation of phosphate metabolic process GO:0045937 139 0.068
organic substance catabolic process GO:1901575 308 0.067
developmental growth GO:0048589 280 0.067
peripheral nervous system development GO:0007422 52 0.067
regulation of multicellular organismal development GO:2000026 414 0.067
negative regulation of signaling GO:0023057 219 0.066
regulation of nucleotide metabolic process GO:0006140 62 0.066
purine nucleoside triphosphate metabolic process GO:0009144 119 0.065
regulation of neuron differentiation GO:0045664 103 0.065
positive regulation of gtp catabolic process GO:0033126 43 0.065
heterocycle catabolic process GO:0046700 166 0.063
intracellular signal transduction GO:0035556 300 0.063
regulation of small gtpase mediated signal transduction GO:0051056 93 0.062
protein modification process GO:0036211 438 0.062
regulation of nervous system development GO:0051960 248 0.061
purine ribonucleoside metabolic process GO:0046128 127 0.061
positive regulation of nucleotide metabolic process GO:0045981 55 0.061
salivary gland development GO:0007431 162 0.061
regulation of purine nucleotide metabolic process GO:1900542 62 0.060
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.060
positive regulation of biosynthetic process GO:0009891 316 0.059
axonogenesis GO:0007409 290 0.059
regulation of nucleotide catabolic process GO:0030811 48 0.057
photoreceptor cell differentiation GO:0046530 170 0.056
regulation of lamellipodium organization GO:1902743 15 0.056
purine ribonucleotide catabolic process GO:0009154 109 0.055
positive regulation of ras gtpase activity GO:0032320 36 0.055
organelle localization GO:0051640 148 0.055
regulation of response to external stimulus GO:0032101 115 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.054
negative regulation of response to stimulus GO:0048585 258 0.054
positive regulation of catabolic process GO:0009896 105 0.054
positive regulation of gtpase activity GO:0043547 43 0.053
nucleoside triphosphate metabolic process GO:0009141 120 0.052
cellular ketone metabolic process GO:0042180 24 0.051
positive regulation of cellular catabolic process GO:0031331 95 0.051
macromolecular complex assembly GO:0065003 256 0.050
leg disc morphogenesis GO:0007478 80 0.050
regulation of phosphorus metabolic process GO:0051174 210 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
regulation of intracellular signal transduction GO:1902531 236 0.048
ribonucleoside triphosphate metabolic process GO:0009199 119 0.048
open tracheal system development GO:0007424 204 0.048
protein acylation GO:0043543 42 0.047
purine nucleoside metabolic process GO:0042278 127 0.047
sensory perception GO:0007600 196 0.047
regulation of gtpase activity GO:0043087 44 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
gene silencing GO:0016458 138 0.046
response to endogenous stimulus GO:0009719 119 0.046
camera type eye development GO:0043010 4 0.045
neural precursor cell proliferation GO:0061351 75 0.045
cytoskeleton dependent cytokinesis GO:0061640 81 0.045
chemotaxis GO:0006935 249 0.044
epidermal cell differentiation GO:0009913 51 0.044
protein complex assembly GO:0006461 200 0.044
regulation of cell cycle process GO:0010564 181 0.044
regulation of purine nucleotide catabolic process GO:0033121 48 0.043
ommochrome biosynthetic process GO:0006727 19 0.043
positive regulation of catalytic activity GO:0043085 118 0.042
positive regulation of molecular function GO:0044093 136 0.042
positive regulation of lipid metabolic process GO:0045834 4 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
brain development GO:0007420 120 0.041
cell division GO:0051301 248 0.041
negative regulation of cellular metabolic process GO:0031324 382 0.041
epidermal growth factor receptor signaling pathway GO:0007173 58 0.040
biological adhesion GO:0022610 138 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.040
peptidyl amino acid modification GO:0018193 105 0.040
positive regulation of gene expression GO:0010628 290 0.039
nucleobase containing compound catabolic process GO:0034655 165 0.039
localization of cell GO:0051674 257 0.039
forebrain development GO:0030900 2 0.039
protein complex biogenesis GO:0070271 201 0.038
exocrine system development GO:0035272 162 0.038
regulation of ras protein signal transduction GO:0046578 93 0.037
regulation of phosphate metabolic process GO:0019220 210 0.037
phagocytosis GO:0006909 215 0.037
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.037
dendrite development GO:0016358 204 0.036
protein phosphorylation GO:0006468 169 0.036
rho protein signal transduction GO:0007266 14 0.036
regulation of organelle organization GO:0033043 196 0.036
actin cytoskeleton organization GO:0030036 206 0.036
ribonucleoside catabolic process GO:0042454 112 0.036
axon development GO:0061564 297 0.036
regulation of localization GO:0032879 275 0.036
amine metabolic process GO:0009308 12 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
lipid localization GO:0010876 54 0.034
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
membrane organization GO:0061024 112 0.034
regulation of cellular amine metabolic process GO:0033238 3 0.034
response to light stimulus GO:0009416 124 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
regulation of notch signaling pathway GO:0008593 100 0.033
developmental growth involved in morphogenesis GO:0060560 65 0.033
positive regulation of nucleoside metabolic process GO:0045979 47 0.033
embryonic development via the syncytial blastoderm GO:0001700 148 0.033
regulation of catalytic activity GO:0050790 185 0.033
cell projection assembly GO:0030031 94 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.032
establishment of localization in cell GO:0051649 402 0.032
mesoderm development GO:0007498 78 0.032
embryo development ending in birth or egg hatching GO:0009792 152 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.031
positive regulation of transcription dna templated GO:0045893 266 0.030
embryonic morphogenesis GO:0048598 206 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
dendrite morphogenesis GO:0048813 199 0.029
appendage morphogenesis GO:0035107 397 0.029
oxoacid metabolic process GO:0043436 103 0.029
regulation of hydrolase activity GO:0051336 97 0.029
carboxylic acid metabolic process GO:0019752 92 0.028
locomotory behavior GO:0007626 176 0.028
cellular response to radiation GO:0071478 52 0.028
response to radiation GO:0009314 155 0.028
hematopoietic or lymphoid organ development GO:0048534 57 0.028
mitotic cell cycle phase transition GO:0044772 138 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
hindbrain development GO:0030902 2 0.027
tube morphogenesis GO:0035239 191 0.027
regionalization GO:0003002 416 0.027
salivary gland morphogenesis GO:0007435 145 0.027
gland morphogenesis GO:0022612 145 0.027
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
regulation of cell proliferation GO:0042127 163 0.027
ocellus pigment metabolic process GO:0046158 19 0.027
central nervous system development GO:0007417 201 0.027
glial cell migration GO:0008347 31 0.026
nephron tubule development GO:0072080 3 0.026
cell motility GO:0048870 251 0.026
gastrulation GO:0007369 70 0.026
cellular response to light stimulus GO:0071482 37 0.026
carbohydrate derivative biosynthetic process GO:1901137 85 0.026
nephron epithelium development GO:0072009 3 0.025
muscle structure development GO:0061061 224 0.025
protein localization GO:0008104 284 0.025
regulation of gtp catabolic process GO:0033124 44 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
response to organic substance GO:0010033 284 0.024
cellular protein localization GO:0034613 160 0.024
cellular response to organic substance GO:0071310 132 0.024
cellular amine metabolic process GO:0044106 12 0.024
positive regulation of signaling GO:0023056 243 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
pigment metabolic process involved in pigmentation GO:0043474 33 0.024
positive regulation of developmental process GO:0051094 143 0.024
negative regulation of developmental process GO:0051093 201 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
adult behavior GO:0030534 137 0.023
ocellus pigmentation GO:0033060 19 0.023
regulation of multi organism process GO:0043900 131 0.023
multicellular organismal aging GO:0010259 140 0.023
regulation of rho gtpase activity GO:0032319 20 0.023
mitotic cytokinesis GO:0000281 50 0.023
response to lipopolysaccharide GO:0032496 4 0.023
organelle fusion GO:0048284 46 0.023
ion transport GO:0006811 145 0.023
proteasomal protein catabolic process GO:0010498 59 0.023
regulation of cellular localization GO:0060341 136 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
gland development GO:0048732 191 0.022
regulation of response to stress GO:0080134 200 0.022
notch signaling pathway GO:0007219 120 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
negative regulation of gene expression GO:0010629 387 0.022
striated muscle cell differentiation GO:0051146 90 0.022
tissue morphogenesis GO:0048729 297 0.022
actin filament based process GO:0030029 220 0.022
regulation of rho protein signal transduction GO:0035023 20 0.021
epithelial cell development GO:0002064 274 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
eye development GO:0001654 323 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
neuroblast proliferation GO:0007405 74 0.021
neuron recognition GO:0008038 101 0.021
epidermis development GO:0008544 65 0.021
response to abiotic stimulus GO:0009628 341 0.021
regulation of protein complex assembly GO:0043254 42 0.021
cell proliferation GO:0008283 299 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
positive regulation of nucleotide catabolic process GO:0030813 46 0.020
skin development GO:0043588 65 0.020
protein acetylation GO:0006473 39 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
sensory perception of mechanical stimulus GO:0050954 72 0.020
organic substance transport GO:0071702 257 0.020
synaptic growth at neuromuscular junction GO:0051124 119 0.020
retina development in camera type eye GO:0060041 4 0.020
camera type eye morphogenesis GO:0048593 2 0.020
regulation of transport GO:0051049 181 0.020
proteolysis GO:0006508 192 0.020
pigmentation GO:0043473 75 0.020
hair cell differentiation GO:0035315 47 0.020
epithelial cell differentiation GO:0030855 322 0.020
cell migration GO:0016477 238 0.020
wing disc morphogenesis GO:0007472 344 0.019
digestive tract development GO:0048565 149 0.019
peptidyl lysine modification GO:0018205 57 0.019
gliogenesis GO:0042063 80 0.019
positive regulation of organelle organization GO:0010638 65 0.019
synaptic transmission GO:0007268 288 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
telencephalon development GO:0021537 2 0.019
regulation of tube length open tracheal system GO:0035159 24 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
positive regulation of rac gtpase activity GO:0032855 8 0.019
regulation of neurogenesis GO:0050767 158 0.019
regulation of erbb signaling pathway GO:1901184 42 0.019
apoptotic process GO:0006915 159 0.018
regulation of cell cycle GO:0051726 291 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
positive regulation of cell communication GO:0010647 250 0.018
single organism cellular localization GO:1902580 180 0.018
regulation of developmental growth GO:0048638 174 0.018
actin filament organization GO:0007015 126 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
cell cycle checkpoint GO:0000075 95 0.018
regulation of cell shape GO:0008360 113 0.018
embryonic organ development GO:0048568 50 0.018
ommochrome metabolic process GO:0046152 19 0.018
kidney development GO:0001822 3 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.017
synapse assembly GO:0007416 143 0.017
head development GO:0060322 135 0.017
regulation of gene silencing GO:0060968 63 0.017
positive regulation of signal transduction GO:0009967 223 0.017
response to wounding GO:0009611 94 0.017
regulation of secretion GO:0051046 44 0.017
lateral inhibition GO:0046331 206 0.017
ocellus pigment biosynthetic process GO:0008055 19 0.017
positive regulation of nervous system development GO:0051962 69 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
regulation of protein modification process GO:0031399 112 0.017
benzene containing compound metabolic process GO:0042537 3 0.017
eye morphogenesis GO:0048592 260 0.017
negative regulation of nervous system development GO:0051961 92 0.017
regulation of anatomical structure size GO:0090066 163 0.016
compound eye morphogenesis GO:0001745 249 0.016
centrosome organization GO:0051297 163 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
establishment of protein localization GO:0045184 163 0.016
histone acetylation GO:0016573 38 0.016
regulation of phosphorylation GO:0042325 147 0.016
secondary metabolite biosynthetic process GO:0044550 24 0.016
establishment of glial blood brain barrier GO:0060857 14 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
cytokinesis GO:0000910 90 0.016
ocellus development GO:0008056 4 0.016
memory GO:0007613 94 0.016
cell adhesion GO:0007155 136 0.016
regulation of cell development GO:0060284 215 0.016
morphogenesis of an epithelium GO:0002009 276 0.015
innate immune response activating signal transduction GO:0002758 2 0.015
negative regulation of signal transduction GO:0009968 206 0.015
chromosome organization GO:0051276 360 0.015
sensory perception of chemical stimulus GO:0007606 116 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
integrin mediated signaling pathway GO:0007229 3 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
myotube cell development GO:0014904 3 0.015
peptidyl lysine acetylation GO:0018394 39 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
lipid storage GO:0019915 38 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
stem cell proliferation GO:0072089 88 0.015
alpha amino acid metabolic process GO:1901605 20 0.015
mesenchymal cell development GO:0014031 1 0.015
histone modification GO:0016570 106 0.014
cortical cytoskeleton organization GO:0030865 29 0.014
regulation of embryonic development GO:0045995 68 0.014
nephron tubule morphogenesis GO:0072078 3 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
cell cycle phase transition GO:0044770 140 0.014
mitochondrion organization GO:0007005 65 0.014
single organism membrane organization GO:0044802 93 0.014
maintenance of location GO:0051235 73 0.014
regulation of microtubule based process GO:0032886 49 0.014
lamellipodium assembly GO:0030032 21 0.014
cellular protein catabolic process GO:0044257 83 0.014
phosphorylation GO:0016310 294 0.014
response to glucose GO:0009749 2 0.014
response to extracellular stimulus GO:0009991 116 0.014
cell cell junction organization GO:0045216 55 0.014
organic acid metabolic process GO:0006082 103 0.014
positive regulation of cell motility GO:2000147 3 0.014
learning or memory GO:0007611 141 0.014
endomembrane system organization GO:0010256 119 0.014
regulation of proteolysis GO:0030162 87 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
response to nitrogen compound GO:1901698 90 0.014
digestive system development GO:0055123 149 0.014
myotube differentiation GO:0014902 46 0.014
response to monosaccharide GO:0034284 4 0.014
lamellipodium organization GO:0097581 21 0.014
response to nutrient levels GO:0031667 114 0.014
pattern recognition receptor signaling pathway GO:0002221 2 0.013
regulation of cell division GO:0051302 72 0.013
cell recognition GO:0008037 102 0.013
heart development GO:0007507 82 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
male mating behavior GO:0060179 70 0.013
internal peptidyl lysine acetylation GO:0018393 38 0.013
positive regulation of protein deacetylation GO:0090312 2 0.013
growth GO:0040007 359 0.013
maintenance of cell polarity GO:0030011 18 0.013
protein heterooligomerization GO:0051291 4 0.013
cellular macromolecule localization GO:0070727 220 0.013
cell death GO:0008219 279 0.013
retina morphogenesis in camera type eye GO:0060042 2 0.013
mushroom body development GO:0016319 70 0.013
wing disc pattern formation GO:0035222 66 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
positive regulation of immune effector process GO:0002699 28 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.013
initiation of dorsal closure GO:0007392 12 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
microtubule organizing center organization GO:0031023 168 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
death GO:0016265 284 0.012
monocarboxylic acid transport GO:0015718 3 0.012
nucleoside phosphate biosynthetic process GO:1901293 34 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
imaginal disc derived wing hair organization GO:0035317 45 0.012
sex differentiation GO:0007548 81 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
branching morphogenesis of an epithelial tube GO:0048754 45 0.012
tube development GO:0035295 244 0.012
establishment of organelle localization GO:0051656 122 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of cell differentiation GO:0045595 302 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
nucleus localization GO:0051647 34 0.012
cognition GO:0050890 141 0.012
regulation of locomotion GO:0040012 42 0.012
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
organelle assembly GO:0070925 198 0.012
immune response activating signal transduction GO:0002757 2 0.012
cell junction assembly GO:0034329 42 0.012
stem cell differentiation GO:0048863 117 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
cell growth GO:0016049 108 0.012
defense response to other organism GO:0098542 225 0.012
nephron development GO:0072006 3 0.011
protein polymerization GO:0051258 42 0.011
erbb signaling pathway GO:0038127 58 0.011
regulation of programmed cell death GO:0043067 152 0.011
actin cytoskeleton reorganization GO:0031532 22 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
anion transport GO:0006820 41 0.011
positive regulation of proteolysis GO:0045862 52 0.011
reproductive system development GO:0061458 74 0.011
carbohydrate metabolic process GO:0005975 82 0.011
positive regulation of cell migration GO:0030335 2 0.011
response to organic cyclic compound GO:0014070 89 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
adult locomotory behavior GO:0008344 76 0.011
regulation of actin filament based process GO:0032970 42 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
protein ubiquitination GO:0016567 70 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
myoblast fusion GO:0007520 43 0.011
response to endoplasmic reticulum stress GO:0034976 28 0.011
response to oxygen containing compound GO:1901700 200 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
internal protein amino acid acetylation GO:0006475 38 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
chromatin modification GO:0016568 147 0.010
limb development GO:0060173 1 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
protein transport GO:0015031 155 0.010
photoreceptor cell development GO:0042461 96 0.010
regulation of ras gtpase activity GO:0032318 38 0.010
mitotic cell cycle checkpoint GO:0007093 88 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
cilium assembly GO:0042384 38 0.010
intracellular transport GO:0046907 228 0.010
single organismal cell cell adhesion GO:0016337 45 0.010
nuclear division GO:0000280 332 0.010
positive regulation of cell proliferation GO:0008284 47 0.010
single organism intracellular transport GO:1902582 207 0.010
immune system development GO:0002520 57 0.010
regulation of microtubule cytoskeleton organization GO:0070507 41 0.010
pigment biosynthetic process GO:0046148 36 0.010
larval development GO:0002164 104 0.010

Flo-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.012
bone disease DOID:0080001 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011